Journal of the National Cancer Institute

Journal of the National Cancer Institute
Author: Anonim
Publsiher: Anonim
Total Pages: 329
Release: 2008
ISBN 10:
ISBN 13: OSU:32435080704174
Language: EN, FR, DE, ES & NL

Journal of the National Cancer Institute Book Review:

JAMA

JAMA
Author: Anonim
Publsiher: Anonim
Total Pages: 329
Release: 2003
ISBN 10:
ISBN 13: NWU:35558004989311
Language: EN, FR, DE, ES & NL

JAMA Book Review:

Journal of the National Cancer Institute

Journal of the National Cancer Institute
Author: Anonim
Publsiher: Anonim
Total Pages: 329
Release: 2003
ISBN 10:
ISBN 13: NWU:35558004949935
Language: EN, FR, DE, ES & NL

Journal of the National Cancer Institute Book Review:

"Summaries of papers" contained in the journal accompany each issue, 19--

The New England Journal of Medicine

The New England Journal of Medicine
Author: Anonim
Publsiher: Anonim
Total Pages: 329
Release: 2008
ISBN 10:
ISBN 13: UCSD:31822034143735
Language: EN, FR, DE, ES & NL

The New England Journal of Medicine Book Review:

Designing Clinical Research

Designing Clinical Research
Author: Stephen B. Hulley,Steven R. Cummings,Warren S. Browner,Deborah G. Grady,Thomas B. Newman
Publsiher: Lippincott Williams & Wilkins
Total Pages: 384
Release: 2011-11-30
ISBN 10: 1451165854
ISBN 13: 9781451165852
Language: EN, FR, DE, ES & NL

Designing Clinical Research Book Review:

Designing Clinical Research sets the standard for providing a practical guide to planning, tabulating, formulating, and implementing clinical research, with an easy-to-read, uncomplicated presentation. This edition incorporates current research methodology—including molecular and genetic clinical research—and offers an updated syllabus for conducting a clinical research workshop. Emphasis is on common sense as the main ingredient of good science. The book explains how to choose well-focused research questions and details the steps through all the elements of study design, data collection, quality assurance, and basic grant-writing. All chapters have been thoroughly revised, updated, and made more user-friendly.

The Vanishing Physician-Scientist?

The Vanishing Physician-Scientist?
Author: Andrew I. Schafer
Publsiher: Cornell University Press
Total Pages: 304
Release: 2011-06-15
ISBN 10: 0801462428
ISBN 13: 9780801462429
Language: EN, FR, DE, ES & NL

The Vanishing Physician-Scientist? Book Review:

Throughout history, physicians have played a vital role in medical discovery. These physician-scientists devote the majority of their professional effort to seeking new knowledge about health and disease through research and represent the entire continuum of biomedical investigation. They bring a unique perspective to their work and often base their scientific questions on the experience of caring for patients. Physician-scientists also effectively communicate between researchers in the "pure sciences" and practicing health care providers. Yet there has been growing concern in recent decades that, due to complex changes, physician-scientists are vanishing from the scene. In this book, leading physician-scientists and academic physicians examine the problem from a variety of perspectives: historical, demographic, scientific, cultural, sociological, and economic. They make valuable recommendations that—if heeded—should preserve and revitalize the community of physician-scientists as the profession continues to evolve and boundaries between doctors and researchers shift.

Peptide Drug Discovery and Development

Peptide Drug Discovery and Development
Author: Miguel Castanho,Nuno Santos
Publsiher: John Wiley & Sons
Total Pages: 390
Release: 2011-10-24
ISBN 10: 3527636749
ISBN 13: 9783527636747
Language: EN, FR, DE, ES & NL

Peptide Drug Discovery and Development Book Review:

Filling a real knowledge gap, this handbook and ready reference is both modern and forward-looking in its emphasis on the "bench to bedside" translational approach to drug development. Clearly structured into three major parts, the book stakes out the boundaries of peptide drug development in the preclinical as well as clinical stages. The first part provides a general background and focuses on the characteristic strengths and weaknesses of peptide drugs. The second section contains five cases studies of peptides from diverse therapeutic fields, and the lessons to be learned from them, while the final part looks at new targets and opportunities, discussing several drug targets and diseases for which peptide drugs are currently being developed.

Intervention Research

Intervention Research
Author: Bernadette Mazurek Melnyk, PhD, RN, CPNP/ PMHNP, FNAP, FAAN,Dianne Morrison-Beedy, PhD, RN, WHNP, FNAP, FAANP, FAAN
Publsiher: Springer Publishing Company
Total Pages: 496
Release: 2012-04-23
ISBN 10: 0826109586
ISBN 13: 9780826109583
Language: EN, FR, DE, ES & NL

Intervention Research Book Review:

2012 First Place AJN Book of the Year Award Winner in Nursing Research! "This is a resource for success and should be a part of any researcher's library."--Doody's Medical Reviews This book is a practical, user-friendly guide for health care researchers across multiple disciplines who are involved in intervention research. It provides all of the essential elements needed for understanding how to design, conduct, analyze, and fund intervention studies that are replicable and can withstand the scrutiny of the Institutional Review Board and peer review. Developed from an annual continuing education workshop on intervention studies conducted by Dr. Melnyk, this text is the most comprehensive body of information available on this topic. Contributors address the design of interventions that are ethically considerate and sensitive to culture, race/ethnicity, and gender, minimizing threats to external and internal validity, measurement, and budgeting. The guide explores such implementation issues as subject recruitment and retention, data management, and specialized settings, cost analysis, and explaining intervention effects. The text also guides readers in writing grant applications that fund , and addresses how to move intervention study findings into the real world. A unique addition to the book is the availability of digital examples of progress reports, final reports, and research grant applications that have received funding from the National Institutes of Health and other relevant organizations. This text is a valuable resource for all health care professionals conducting research and for doctoral students in health care studies. Key Features: Presents the essential tools for designing, conducting, analyzing, and funding intervention studies Designed for use by health care professionals conducting intervention research Provides comprehensive, accessible guidelines for doctoral students across all health care disciplines Instructs readers on writing grant applications that fund Includes digital examples of funded research grants, progress reports, and final reports

Research Report

Research Report
Author: Anonim
Publsiher: Anonim
Total Pages: 329
Release: 1999
ISBN 10:
ISBN 13: CHI:58625848
Language: EN, FR, DE, ES & NL

Research Report Book Review:

Integrating Clinical Research into Epidemic Response

Integrating Clinical Research into Epidemic Response
Author: National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Sciences Policy,Board on Global Health,Committee on Clinical Trials During the 2014-2015 Ebola Outbreak
Publsiher: National Academies Press
Total Pages: 342
Release: 2017-07-26
ISBN 10: 0309457769
ISBN 13: 9780309457767
Language: EN, FR, DE, ES & NL

Integrating Clinical Research into Epidemic Response Book Review:

The 2014â€"2015 Ebola epidemic in western Africa was the longest and most deadly Ebola epidemic in history, resulting in 28,616 cases and 11,310 deaths in Guinea, Liberia, and Sierra Leone. The Ebola virus has been known since 1976, when two separate outbreaks were identified in the Democratic Republic of Congo (then Zaire) and South Sudan (then Sudan). However, because all Ebola outbreaks prior to that in West Africa in 2014â€"2015 were relatively isolated and of short duration, little was known about how to best manage patients to improve survival, and there were no approved therapeutics or vaccines. When the World Heath Organization declared the 2014-2015 epidemic a public health emergency of international concern in August 2014, several teams began conducting formal clinical trials in the Ebola affected countries during the outbreak. Integrating Clinical Research into Epidemic Response: The Ebola Experience assesses the value of the clinical trials held during the 2014â€"2015 epidemic and makes recommendations about how the conduct of trials could be improved in the context of a future international emerging or re-emerging infectious disease events.

Issues in Discovery, Experimental, and Laboratory Medicine: 2011 Edition

Issues in Discovery, Experimental, and Laboratory Medicine: 2011 Edition
Author: Anonim
Publsiher: ScholarlyEditions
Total Pages: 3453
Release: 2012-01-09
ISBN 10: 1464963509
ISBN 13: 9781464963506
Language: EN, FR, DE, ES & NL

Issues in Discovery, Experimental, and Laboratory Medicine: 2011 Edition Book Review:

Issues in Discovery, Experimental, and Laboratory Medicine: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Discovery, Experimental, and Laboratory Medicine. The editors have built Issues in Discovery, Experimental, and Laboratory Medicine: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Discovery, Experimental, and Laboratory Medicine in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Discovery, Experimental, and Laboratory Medicine: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Mixed Methods in Health Sciences Research

Mixed Methods in Health Sciences Research
Author: Leslie Curry,Marcella Nunez-Smith
Publsiher: SAGE Publications
Total Pages: 432
Release: 2014-09-30
ISBN 10: 1483347141
ISBN 13: 9781483347141
Language: EN, FR, DE, ES & NL

Mixed Methods in Health Sciences Research Book Review:

Mixed Methods in Health Sciences Research: A Practical Primer, by Leslie Curry and Marcella Nunez-Smith, presents key theories, concepts, and approaches in an accessible way. Packed with illustrations from the health sciences literature, this ready-to-use guidebook shows readers how to design, conduct, review, and use mixed methods research findings. Helpful checklists, figures, tables, templates, and much more give readers examples that will elevate the quality of their research, facilitate communication about their methods, and improve efficiency over the course of their projects. Real-world examples and insights from mixed methods researchers provide unique perspectives on every aspect of mixed methods research. This book successfully pulls together foundational mixed methods principles, synthesizes the knowledge base in the field, and translates it for a health science researcher audience. “The content is highly applicable to real life research teams in the areas of clinical research, health services research, and implementation science, providing sound content and practical advice. The authors have synthesized and pull key concepts from a variety of sources to provide a concise resource.” —Linda M. Herrick, South Dakota State University “Everything from the references, to the topics, checklists, conceptual graphic representations, and organizers, interviews, and resources, all contribute to the content and aid with understanding and/or application. … It addresses specific MM research as it pertains to health sciences in a way that other texts just do not even attempt.” —Denise L. Winsor, University of Memphis “[This text is] a very pragmatic approach to mixed methods research; excellent resources, tables, and figures [are] provided, along with cases and examples of value to researchers and grant reviewers. Its relevance to practice, education, and research, as well as to potential policy implications, is a strong focus that would make this a valued textbook for any researcher!” ? —Karen Devereaux Melillo, University of Massachusetts Lowell “The text is cutting edge. It leads the way with its focus on team dynamics. [The authors] succeed in making the book relevant and practical. They also articulate a number of key insights in the area of mixed methods that rarely get addressed, such as teams and conflict. Great read with a lot of good, practical information for mixed methods researchers at all levels. The practical approach of this text makes it an innovative and valuable resource.” —John G. Schumacher, University of Maryland

Design and Analysis of Clinical Trials

Design and Analysis of Clinical Trials
Author: Shein-Chung Chow,Jen-Pei Liu
Publsiher: Wiley-Interscience
Total Pages: 649
Release: 1998-06-23
ISBN 10:
ISBN 13: UOM:39015047055416
Language: EN, FR, DE, ES & NL

Design and Analysis of Clinical Trials Book Review:

A unique, unifying treatment for statistics and science in clinical trials What sets this volume apart from the many books dealing with clinical trials is its integration of statistical and clinical disciplines. Stressing communication between biostatisticians and clinical scientists, this work clearly relates statistical interpretation to clinical issues arising in different stages of pharmaceutical research and development. Plus, the principles presented here are universal enough to be easily adapted in non-biopharmaceutical settings. Design and Analysis of Clinical Trials tackles concepts and methodologies. It not only covers statistical basics such as uncertainty and bias, design considerations such as patient selection, randomization, and the different types of clinical trials but also deals with various methods of data analysis, group sequential procedures for interim analysis, efficacy data evaluation, analysis of safety data, and more. Throughout, the book: * Surveys current and emerging clinical issues and newly developed statistical methods * Presents a critical review of statistical methodologies in various therapeutic areas * Features case studies from actual clinical trials * Minimizes the mathematics involved, making the material widely accessible * Offers each chapter as a self-contained entity * Includes illustrations to highlight the text This monumental reference on all facets of clinical trials is important reading for physicians, clinical and medical researchers, pharmaceutical scientists, clinical programmers, biostatisticians, and anyone involved in this burgeoning area of clinical research. It can also be used as a textbook in graduate-level courses in the field.

Early Detection of Cancer

Early Detection of Cancer
Author: Sudhir Srivastava
Publsiher: IOS Press
Total Pages: 98
Release: 2005
ISBN 10: 9781586035525
ISBN 13: 1586035525
Language: EN, FR, DE, ES & NL

Early Detection of Cancer Book Review:

Technological inventions allow us to identify molecular events that will effectively detect cancer earlier in biological specimens. This approach enables us to develop molecular biomarkers for detecting cancer early. It is believed that such a molecular marker approach enables the detection of the disease earlier.

Immunotherapy in Translational Cancer Research

Immunotherapy in Translational Cancer Research
Author: Laurence J. N. Cooper,Elizabeth A. Mittendorf,Judy Moyes,Sabitha Prabhakaran
Publsiher: John Wiley & Sons
Total Pages: 312
Release: 2018-05-01
ISBN 10: 1118123220
ISBN 13: 9781118123225
Language: EN, FR, DE, ES & NL

Immunotherapy in Translational Cancer Research Book Review:

A guide to state-of-the-art cancer immunotherapy in translational cancer research A volume in the Translational Oncology series, Immunotherapy in Translational Cancer Research explores the recent developments in the role that immunotherapy plays in the treatment of a wide range of cancers. The editors present key concepts, illustrative examples, and suggest alternative strategies in order to achieve individualized targeted therapy. Comprehensive in scope, Immunotherapy in Translational Cancer Research reviews the relevant history, current state, and the future of burgeoning cancer-fighting therapies. The book also includes critical information on drug development, clinical trials, and governmental resources and regulatory issues. Each chapter is created to feature: development of the immunotherapy; challenges that have been overcome in order to scale up and undertake clinical trials; and clinical experience and application of research. This authoritative volume is edited by a team of noted experts from MD Anderson Cancer Center, the world’s foremost cancer research and care center and: Offers a comprehensive presentation of state-of-the-art cancer immunotherapy research that accelerates the pace of clinical cancer care Filled with the concepts, examples, and approaches for developing individualized therapy Explores the breath of treatments that reflect the complexity of the immune system itself Includes contributions from a panel international experts in the field of immunotherapy Designed for physicians, medical students, scientists, pharmaceutical executives, public health and public policy government leaders and community oncologists, this essential resource offers a guide to the bidirectional interaction between laboratory and clinic immunotherapy cancer research.

Transforming Clinical Research in the United States

Transforming Clinical Research in the United States
Author: Institute of Medicine,Board on Health Sciences Policy,Forum on Drug Discovery, Development, and Translation
Publsiher: National Academies Press
Total Pages: 150
Release: 2010-10-22
ISBN 10: 9780309163354
ISBN 13: 0309163358
Language: EN, FR, DE, ES & NL

Transforming Clinical Research in the United States Book Review:

An ideal health care system relies on efficiently generating timely, accurate evidence to deliver on its promise of diminishing the divide between clinical practice and research. There are growing indications, however, that the current health care system and the clinical research that guides medical decisions in the United States falls far short of this vision. The process of generating medical evidence through clinical trials in the United States is expensive and lengthy, includes a number of regulatory hurdles, and is based on a limited infrastructure. The link between clinical research and medical progress is also frequently misunderstood or unsupported by both patients and providers. The focus of clinical research changes as diseases emerge and new treatments create cures for old conditions. As diseases evolve, the ultimate goal remains to speed new and improved medical treatments to patients throughout the world. To keep pace with rapidly changing health care demands, clinical research resources need to be organized and on hand to address the numerous health care questions that continually emerge. Improving the overall capacity of the clinical research enterprise will depend on ensuring that there is an adequate infrastructure in place to support the investigators who conduct research, the patients with real diseases who volunteer to participate in experimental research, and the institutions that organize and carry out the trials. To address these issues and better understand the current state of clinical research in the United States, the Institute of Medicine's (IOM) Forum on Drug Discovery, Development, and Translation held a 2-day workshop entitled Transforming Clinical Research in the United States. The workshop, summarized in this volume, laid the foundation for a broader initiative of the Forum addressing different aspects of clinical research. Future Forum plans include further examining regulatory, administrative, and structural barriers to the effective conduct of clinical research; developing a vision for a stable, continuously funded clinical research infrastructure in the United States; and considering strategies and collaborative activities to facilitate more robust public engagement in the clinical research enterprise.

Clinical Trials

Clinical Trials
Author: Steven Piantadosi
Publsiher: John Wiley & Sons
Total Pages: 720
Release: 2013-05-29
ISBN 10: 1118625854
ISBN 13: 9781118625859
Language: EN, FR, DE, ES & NL

Clinical Trials Book Review:

Learn rigorous statistical methods to ensure valid clinicaltrials This Second Edition of the critically hailed Clinical Trials buildson the text's reputation as a straightforward and authoritativepresentation of statistical methods for clinical trials. Readersare introduced to the fundamentals of design for various types ofclinical trials and then skillfully guided through the completeprocess of planning the experiment, assembling a study cohort,assessing data, and reporting results. Throughout the process, theauthor alerts readers to problems that may arise during the courseof the trial and provides commonsense solutions. The author bases the revisions and updates on his own classroomexperience, as well as feedback from students, instructors, andmedical and statistical professionals involved in clinical trials.The Second Edition greatly expands its coverage, ranging fromstatistical principles to controversial topics, includingalternative medicine and ethics. At the same time, it offers morepragmatic advice for issues such as selecting outcomes, samplesize, analysis, reporting, and handling allegations of misconduct.Readers familiar with the First Edition will discover completelynew chapters, including: * Contexts for clinical trials * Statistical perspectives * Translational clinical trials * Dose-finding and dose-ranging designs Each chapter is accompanied by a summary to reinforce the keypoints. Revised discussion questions stimulate critical thinkingand help readers understand how they can apply their newfoundknowledge, and updated references are provided to direct readers tothe most recent literature. This text distinguishes itself with its accessible and broadcoverage of statistical design methods--the crucial building blocksof clinical trials and medical research. Readers learn to conductclinical trials that produce valid qualitative results backed byrigorous statistical methods.

The Age of Anxiety

The Age of Anxiety
Author: Andrea Tone
Publsiher: Basic Books
Total Pages: 320
Release: 2008-12-30
ISBN 10: 0786727470
ISBN 13: 9780786727476
Language: EN, FR, DE, ES & NL

The Age of Anxiety Book Review:

Anxious Americans have increasingly pursued peace of mind through pills and prescriptions. In 2006, the National Institute of Mental Health estimated that 40 million adult Americans suffer from an anxiety disorder in any given year: more than double the number thought to have such a disorder in 2001. Anti-anxiety drugs are a billion-dollar business. Yet as recently as 1955, when the first tranquilizer—Miltown—went on the market, pharmaceutical executives worried that there wouldn't be interest in anxiety-relief. At mid-century, talk therapy remained the treatment of choice. But Miltown became a sensation—the first psychotropic blockbuster in United States history. By 1957, Americans had filled 36 million prescriptions. Patients seeking made-to-order tranquility emptied drugstores, forcing pharmacists to post signs reading “more Miltown tomorrow.” The drug's financial success and cultural impact revolutionized perceptions of anxiety and its treatment, inspiring the development of other lifestyle drugs including Valium and Prozac. In The Age of Anxiety, Andrea Tone draws on a broad array of original sources—manufacturers' files, FDA reports, letters, government investigations, and interviews with inventors, physicians, patients, and activists—to provide the first comprehensive account of the rise of America's tranquilizer culture. She transports readers from the bomb shelters of the Cold War to the scientific optimism of the Baby Boomers, to the “just say no” Puritanism of the late 1970s and 1980s. A vibrant history of America's long and turbulent affair with tranquilizers, The Age of Anxiety casts new light on what it has meant to seek synthetic solutions to everyday angst.

Pediatric Formulations

Pediatric Formulations
Author: Daniel Bar-Shalom,Klaus Rose
Publsiher: Springer Science & Business Media
Total Pages: 439
Release: 2014-01-30
ISBN 10: 1489980113
ISBN 13: 9781489980113
Language: EN, FR, DE, ES & NL

Pediatric Formulations Book Review:

Until the 1990s, it was generally accepted that medicines were first developed for adults and their use in children was investigated later, if at all. One of the main tasks of hospital pharmacies was the manufacturing of child-appropriate formulations in a more or less makeshift way. The first change came in 1997 with U.S. legislation that rewarded manufacturers to do voluntary pediatric research. Ten years later, the European Union passed legislation that required manufacturers to discuss all pediatric aspects, including formulations, with the regulatory authorities as a condition of starting the registration procedure. In consequence, manufacturers must now cover all age groups, including the youngest ones. So far, pediatric formulations were more a focus for academic researchers. Through the changed regulatory environment, there is now a sudden high commercial demand for age-appropriate formulations. This book begins by highlighting the anatomical, physiological and developmental differences between adults and children of different ages. It goes on to review the existing technologies and attempts to draw a roadmap to better, innovative formulations, in particular for oral administration. The regulatory, clinical, ethical and pharmaceutical framework is also addressed.

Oxford Handbook of Palliative Care

Oxford Handbook of Palliative Care
Author: Max Watson,Caroline Lucas,Andrew Hoy,Jo Wells
Publsiher: Oxford University Press
Total Pages: 1035
Release: 2009-03-26
ISBN 10: 0199234353
ISBN 13: 9780199234356
Language: EN, FR, DE, ES & NL

Oxford Handbook of Palliative Care Book Review:

This practical guide briefly covers the historical and epidemiological background of palliative care and the growth of palliative medicine as a specialty, before dealing with major physical, psychological, spiritual, and symptom management issues from diagnosis to bereavement care.