Control Applications for Biomedical Engineering Systems

Control Applications for Biomedical Engineering Systems
Author: Ahmad Taher Azar
Publsiher: Academic Press
Total Pages: 476
Release: 2020-01-22
ISBN 10: 0128174625
ISBN 13: 9780128174623
Language: EN, FR, DE, ES & NL

Control Applications for Biomedical Engineering Systems Book Review:

Control Applications for Biomedical Engineering Systems presents different control engineering and modeling applications in the biomedical field. It is intended for senior undergraduate or graduate students in both control engineering and biomedical engineering programs. For control engineering students, it presents the application of various techniques already learned in theoretical lectures in the biomedical arena. For biomedical engineering students, it presents solutions to various problems in the field using methods commonly used by control engineers. Points out theoretical and practical issues to biomedical control systems Brings together solutions developed under different settings with specific attention to the validation of these tools in biomedical settings using real-life datasets and experiments Presents significant case studies on devices and applications

Control Theory in Biomedical Engineering

Control Theory in Biomedical Engineering
Author: Olfa Boubaker
Publsiher: Academic Press
Total Pages: 396
Release: 2020-06-30
ISBN 10: 0128226218
ISBN 13: 9780128226216
Language: EN, FR, DE, ES & NL

Control Theory in Biomedical Engineering Book Review:

Control Theory in Biomedical Engineering: Applications in Physiology and Medical Robotics highlights the importance of control theory and feedback control in our lives and explains how this theory is central to future medical developments. Control theory is fundamental for understanding feedback paths in physiological systems (endocrine system, immune system, neurological system) and a concept for building artificial organs. The book is suitable for graduate students and researchers in the control engineering and biomedical engineering fields, and medical students and practitioners seeking to enhance their understanding of physiological processes, medical robotics (legs, hands, knees), and controlling artificial devices (pacemakers, insulin injection devices). Control theory profoundly impacts the everyday lives of a large part of the human population including the disabled and the elderly who use assistive and rehabilitation robots for improving the quality of their lives and increasing their independence. Gives an overview of state-of-the-art control theory in physiology, emphasizing the importance of this theory in the medical field through concrete examples, e.g., endocrine, immune, and neurological systems Takes a comprehensive look at advances in medical robotics and rehabilitation devices and presents case studies focusing on their feedback control Presents the significance of control theory in the pervasiveness of medical robots in surgery, exploration, diagnosis, therapy, and rehabilitation

Biomedical Applications of Control Engineering

Biomedical Applications of Control Engineering
Author: Selim S. Hacısalihzade
Publsiher: Springer
Total Pages: 274
Release: 2013-03-21
ISBN 10: 3642372791
ISBN 13: 9783642372797
Language: EN, FR, DE, ES & NL

Biomedical Applications of Control Engineering Book Review:

Biomedical Applications of Control Engineering is a lucidly written textbook for graduate control engineering and biomedical engineering students as well as for medical practitioners who want to get acquainted with quantitative methods. It is based on decades of experience both in control engineering and clinical practice. The book begins by reviewing basic concepts of system theory and the modeling process. It then goes on to discuss control engineering application areas like: Different models for the human operator,dosage and timing optimization in oral drug administration, measuring symptoms of and optimal dopaminergic therapy in Parkinson’s disease, measurement and control of blood glucose levels both naturally and by means of external controllers in diabetes, and control of depth of anaesthesia using inhalational anaesthetic agents like sevoflurane using both fuzzy and state feedback controllers. All chapters include three types of exercises constructed to: Review the concepts discussed in the chapter, allow the reader to apply the newly acquired techniques and subject related facts on simple problems, and indicate directions for open ended theses projects. Appendices on Optimal Control and Fuzzy Control meant as refreshers on those control engineering techniques used throughout the book are also included.

Automatic Control Systems in Biomedical Engineering

Automatic Control Systems in Biomedical Engineering
Author: J. Fernández de Cañete,C. Galindo,J. Barbancho,A. Luque
Publsiher: Springer
Total Pages: 364
Release: 2018-03-12
ISBN 10: 3319757172
ISBN 13: 9783319757179
Language: EN, FR, DE, ES & NL

Automatic Control Systems in Biomedical Engineering Book Review:

This book presents the fundamental principles and challenges encountered in the control of biomedical systems, providing practical solutions and suggesting alternatives. The perspective of the text is based on the system behaviour in the time domain both linear and non-linear, continuous and discrete, helping the reader to be able to interpret the physical significance of mathematical results during control system analysis and design focusing on biomedical engineering applications. Interactive learning is promoted, endowing students with the ability to change parameters and conditions during the simulation and see the effects of these changes, by using interactive MATLAB and SIMULINK software tools, also presenting realistic problems in order to analyse, design and develop automatic control systems. The text is also complemented with MATLAB and SIMULINK exercise files solved to aid students to focus on the fundamental concepts treated throughout the book, following a new pedagogical approach distinct from the classical one whereby fundamental control concepts are introduced together with adequate software tools in order to gain insight on the biomedical engineering control problems. The book is suitable for second or third-year undergraduate students who will find the illustrative examples particularly useful to their studies of control system design and implementation. Lecturers in the control field will find the computer aided design approach as an alternative to teaching the fundamental concepts of feedback analogic and digital control.

Biomedical Applications of Control Engineering

Biomedical Applications of Control Engineering
Author: Selim S. Hacısalihzade
Publsiher: Springer
Total Pages: 274
Release: 2013-04-05
ISBN 10: 9783642372780
ISBN 13: 3642372783
Language: EN, FR, DE, ES & NL

Biomedical Applications of Control Engineering Book Review:

Biomedical Applications of Control Engineering is a lucidly written textbook for graduate control engineering and biomedical engineering students as well as for medical practitioners who want to get acquainted with quantitative methods. It is based on decades of experience both in control engineering and clinical practice. The book begins by reviewing basic concepts of system theory and the modeling process. It then goes on to discuss control engineering application areas like: Different models for the human operator,dosage and timing optimization in oral drug administration, measuring symptoms of and optimal dopaminergic therapy in Parkinson’s disease, measurement and control of blood glucose levels both naturally and by means of external controllers in diabetes, and control of depth of anaesthesia using inhalational anaesthetic agents like sevoflurane using both fuzzy and state feedback controllers. All chapters include three types of exercises constructed to: Review the concepts discussed in the chapter, allow the reader to apply the newly acquired techniques and subject related facts on simple problems, and indicate directions for open ended theses projects. Appendices on Optimal Control and Fuzzy Control meant as refreshers on those control engineering techniques used throughout the book are also included.

Control Systems Design of Bio Robotics and Bio Mechatronics with Advanced Applications

Control Systems Design of Bio Robotics and Bio Mechatronics with Advanced Applications
Author: Ahmad Taher Azar
Publsiher: Academic Press
Total Pages: 502
Release: 2019-11-30
ISBN 10: 0128174641
ISBN 13: 9780128174647
Language: EN, FR, DE, ES & NL

Control Systems Design of Bio Robotics and Bio Mechatronics with Advanced Applications Book Review:

Control Systems Design of Bio-Robotics and Bio-Mechatronics with Advanced Applications delivers essential and advanced bioengineering information on the application of control and robotics technologies in the life sciences. Judging by what we have witnessed so far, this exciting field of control systems and robotics in bioengineering is likely to produce revolutionary breakthroughs over the next decade. While this book is intended for senior undergraduate or graduate students in both control engineering and biomedical engineering programs, it will also appeal to medical researchers and practitioners who want to enhance their quantitative understanding of physiological processes. Focuses on the engineering and scientific principles underlying the extraordinary performance of biomedical robotics and bio-mechatronics Demonstrates the application of principles for designing corresponding algorithms Presents the latest innovative approaches to medical diagnostics and procedures, as well as clinical rehabilitation from the point-of-view of dynamic modeling, system analysis and control

Feedback Control in Systems Biology

Feedback Control in Systems Biology
Author: Carlo Cosentino,Declan Bates
Publsiher: CRC Press
Total Pages: 296
Release: 2011-10-17
ISBN 10: 1439816905
ISBN 13: 9781439816905
Language: EN, FR, DE, ES & NL

Feedback Control in Systems Biology Book Review:

Like engineering systems, biological systems must also operate effectively in the presence of internal and external uncertainty—such as genetic mutations or temperature changes, for example. It is not surprising, then, that evolution has resulted in the widespread use of feedback, and research in systems biology over the past decade has shown that feedback control systems are widely found in biology. As an increasing number of researchers in the life sciences become interested in control-theoretic ideas such as feedback, stability, noise and disturbance attenuation, and robustness, there is a need for a text that explains feedback control as it applies to biological systems. Written by established researchers in both control engineering and systems biology, Feedback Control in Systems Biology explains how feedback control concepts can be applied to systems biology. Filling the need for a text on control theory for systems biologists, it provides an overview of relevant ideas and methods from control engineering and illustrates their application to the analysis of biological systems with case studies in cellular and molecular biology. Control Theory for Systems Biologists The book focuses on the fundamental concepts used to analyze the effects of feedback in biological control systems, rather than the control system design methods that form the core of most control textbooks. In addition, the authors do not assume that readers are familiar with control theory. They focus on "control applications" such as metabolic and gene-regulatory networks rather than aircraft, robots, or engines, and on mathematical models derived from classical reaction kinetics rather than classical mechanics. Another significant feature of the book is that it discusses nonlinear systems, an understanding of which is crucial for systems biologists because of the highly nonlinear nature of biological systems. The authors cover tools and techniques for the analysis of linear and nonlinear systems; negative and positive feedback; robustness analysis methods; techniques for the reverse-engineering of biological interaction networks; and the analysis of stochastic biological control systems. They also identify new research directions for control theory inspired by the dynamic characteristics of biological systems. A valuable reference for researchers, this text offers a sound starting point for scientists entering this fascinating and rapidly developing field.

Adaptive Control Systems

Adaptive Control Systems
Author: Chalam
Publsiher: Routledge
Total Pages: 544
Release: 2017-10-19
ISBN 10: 1351468979
ISBN 13: 9781351468978
Language: EN, FR, DE, ES & NL

Adaptive Control Systems Book Review:

impossible to access. It has been widely scattered in papers, reports, and proceedings ofsymposia, with different authors employing different symbols and terms. But now thereis a book that covers all aspects of this dynamic topic in a systematic manner.Featuring consistent terminology and compatible notation, and emphasizing unifiedstrategies, Adaptive Control Systems provides a comprehensive, integrated accountof basic concepts, analytical tools, algorithms, and a wide variety of application trendsand techniques.Adaptive Control Systems deals not only with the two principal approachesmodelreference adaptive control and self-tuning regulators-but also considers otheradaptive strategies involving variable structure systems, reduced order schemes, predictivecontrol, fuzzy logic, and more. In addition, it highlights a large number of practical applicationsin a range of fields from electrical to biomedical and aerospace engineering ...and includes coverage of industrial robots.The book identifies current trends in the development of adaptive control systems ...delineates areas for further research . : . and provides an invaluable bibliography of over1,200 references to the literature.The first authoritative reference in this important area of work, Adaptive ControlSystems is an essential information source for electrical and electronics, R&D,chemical, mechanical, aerospace, biomedical, metallurgical, marine, transportation, andpower plant engineers. It is also useful as a text in professional society seminars and inhousetraining programs for personnel involved with the control of complex systems, andfor graduate students engaged in the study of adaptive control systems.

Physiological Control Systems

Physiological Control Systems
Author: Michael C. K. Khoo
Publsiher: John Wiley & Sons
Total Pages: 456
Release: 2018-04-12
ISBN 10: 1119058805
ISBN 13: 9781119058809
Language: EN, FR, DE, ES & NL

Physiological Control Systems Book Review:

A guide to common control principles and how they are used to characterize a variety of physiological mechanisms The second edition of Physiological Control Systems offers an updated and comprehensive resource that reviews the fundamental concepts of classical control theory and how engineering methodology can be applied to obtain a quantitative understanding of physiological systems. The revised text also contains more advanced topics that feature applications to physiology of nonlinear dynamics, parameter estimation methods, and adaptive estimation and control. The author—a noted expert in the field—includes a wealth of worked examples that illustrate key concepts and methodology and offers in-depth analyses of selected physiological control models that highlight the topics presented. The author discusses the most noteworthy developments in system identification, optimal control, and nonlinear dynamical analysis and targets recent bioengineering advances. Designed to be a practical resource, the text includes guided experiments with simulation models (using Simulink/Matlab). Physiological Control Systems focuses on common control principles that can be used to characterize a broad variety of physiological mechanisms. This revised resource: Offers new sections that explore identification of nonlinear and time-varying systems, and provide the background for understanding the link between continuous-time and discrete-time dynamic models Presents helpful, hands-on experimentation with computer simulation models Contains fully updated problems and exercises at the end of each chapter Written for biomedical engineering students and biomedical scientists, Physiological Control Systems, offers an updated edition of this key resource for understanding classical control theory and its application to physiological systems. It also contains contemporary topics and methodologies that shape bioengineering research today.

Micro Nano Mechatronics

Micro Nano Mechatronics
Author: Chikara Nagai
Publsiher: BoD – Books on Demand
Total Pages: 378
Release: 2013-06-05
ISBN 10: 9535111043
ISBN 13: 9789535111047
Language: EN, FR, DE, ES & NL

Micro Nano Mechatronics Book Review:

Micro/Nano mechatronics is currently used in broader spectra, ranging from basic applications in robotics, actuators, sensors, semiconductors, automobiles, and machine tools. As a strategic technology highlighting the 21st century, this technology is extended to new applications in bio-medical systems and life science, construction machines, and aerospace equipment, welfare/human life engineering, and other brand new scopes. Basically, the miniaturizing technology is important to realize high performance, low energy consumption, low cost performance, small space instrumentation, light-weight, and so on. This book presents the summary of our project Center of Excellence for Education and Research of Micro-Nano Mechatronics. The project implements a strategy to realize applications of micro-nano mechatronics, which are based on mechanical engineering or materials science, control systems engineering, and advanced medical engineering. The chapters describe the research advances in micro/nano measurement and control, micro/nano design and manufacturing, nano materials science, and their applications in biomedical engineering. The publication of this book was supported by Nagoya University, the 21st COE program "Micro- and NanoMechatronics for Information-Based Society," and the global COE program “COE for Education and Research of Micro-Nano Mechatronics.”

Control System Applications

Control System Applications
Author: William S. Levine
Publsiher: CRC Press
Total Pages: 360
Release: 2018-10-24
ISBN 10: 1351838393
ISBN 13: 9781351838399
Language: EN, FR, DE, ES & NL

Control System Applications Book Review:

Control technology permeates every aspect of our lives. We rely on them to perform a wide variety of tasks without giving much thought to the origins of the technology or how it became such an important part of our lives. Control System Applications covers the uses of control systems, both in the common and in the uncommon areas of our lives. From the everyday to the unusual, it's all here. From process control to human-in-the-loop control, this book provides illustrations and examples of how these systems are applied. Each chapter contains an introduction to the application, a section defining terms and references, and a section on further readings that help you understand and use the techniques in your work environment. Highly readable and comprehensive, Control System Applications explores the uses of control systems. It illustrates the diversity of control systems and provides examples of how the theory can be applied to specific practical problems. It contains information about aspec ts of control that are not fully captured by the theory, such as techniques for protecting against controller failure and the role of cost and complexity in specifying controller designs.

Generalized Predictive Control And Bioengineering

Generalized Predictive Control And Bioengineering
Author: M Mahfouf,D. A. Linkens
Publsiher: CRC Press
Total Pages: 500
Release: 1998-08-27
ISBN 10: 9780748405978
ISBN 13: 0748405976
Language: EN, FR, DE, ES & NL

Generalized Predictive Control And Bioengineering Book Review:

Predictive control is a powerful tool in dealing with those processes with large time delays. Generalized Predictive Control GPC is the most popular approach to the subject, and this text discusses the application of GPC starting with the concept of long-range predictive control and its need in medicine particularly automated drug deliveries.; The concept of adaptation is also emphasized with respect to patient-to-patient parameter variations. Subsequent chapters discuss interactions, comparisons and various aspects of GPC. The book concludes by putting into perspective the generic nature of the architecture built around GPC and which provides model-based fault diagnosis with control.

Control of Complex Systems

Control of Complex Systems
Author: Kyriakos Vamvoudakis,Sarangapani Jagannathan
Publsiher: Butterworth-Heinemann
Total Pages: 762
Release: 2016-07-27
ISBN 10: 0128054379
ISBN 13: 9780128054376
Language: EN, FR, DE, ES & NL

Control of Complex Systems Book Review:

In the era of cyber-physical systems, the area of control of complex systems has grown to be one of the hardest in terms of algorithmic design techniques and analytical tools. The 23 chapters, written by international specialists in the field, cover a variety of interests within the broader field of learning, adaptation, optimization and networked control. The editors have grouped these into the following 5 sections: “Introduction and Background on Control Theory”, “Adaptive Control and Neuroscience”, “Adaptive Learning Algorithms”, “Cyber-Physical Systems and Cooperative Control”, “Applications”. The diversity of the research presented gives the reader a unique opportunity to explore a comprehensive overview of a field of great interest to control and system theorists. This book is intended for researchers and control engineers in machine learning, adaptive control, optimization and automatic control systems, including Electrical Engineers, Computer Science Engineers, Mechanical Engineers, Aerospace/Automotive Engineers, and Industrial Engineers. It could be used as a text or reference for advanced courses in complex control systems. • Collection of chapters from several well-known professors and researchers that will showcase their recent work • Presents different state-of-the-art control approaches and theory for complex systems • Gives algorithms that take into consideration the presence of modelling uncertainties, the unavailability of the model, the possibility of cooperative/non-cooperative goals and malicious attacks compromising the security of networked teams • Real system examples and figures throughout, make ideas concrete Includes chapters from several well-known professors and researchers that showcases their recent work Presents different state-of-the-art control approaches and theory for complex systems Explores the presence of modelling uncertainties, the unavailability of the model, the possibility of cooperative/non-cooperative goals, and malicious attacks compromising the security of networked teams Serves as a helpful reference for researchers and control engineers working with machine learning, adaptive control, and automatic control systems

Control in Bioprocessing

Control in Bioprocessing
Author: Pablo A. López Pérez,Ricardo Aguilar López,Ricardo Femat
Publsiher: John Wiley & Sons
Total Pages: 296
Release: 2020-03-03
ISBN 10: 1119296080
ISBN 13: 9781119296089
Language: EN, FR, DE, ES & NL

Control in Bioprocessing Book Review:

Closes the gap between bioscience and mathematics-based process engineering This book presents the most commonly employed approaches in the control of bioprocesses. It discusses the role that control theory plays in understanding the mechanisms of cellular and metabolic processes, and presents key results in various fields such as dynamic modeling, dynamic properties of bioprocess models, software sensors designed for the online estimation of parameters and state variables, and control and supervision of bioprocesses Control in Bioengineering and Bioprocessing: Modeling, Estimation and the Use of Sensors is divided into three sections. Part I, Mathematical preliminaries and overview of the control and monitoring of bioprocess, provides a general overview of the control and monitoring of bioprocesses, and introduces the mathematical framework necessary for the analysis and characterization of bioprocess dynamics. Part II, Observability and control concepts, presents the observability concepts which form the basis of design online estimation algorithms (software sensor) for bioprocesses, and reviews controllability of these concepts, including automatic feedback control systems. Part III, Software sensors and observer-based control schemes for bioprocesses, features six application cases including dynamic behavior of 3-dimensional continuous bioreactors; observability analysis applied to 2D and 3D bioreactors with inhibitory and non-inhibitory models; and regulation of a continuously stirred bioreactor via modeling error compensation. Applicable across all areas of bioprocess engineering, including food and beverages, biofuels and renewable energy, pharmaceuticals and nutraceuticals, fermentation systems, product separation technologies, wastewater and solid-waste treatment technology, and bioremediation Provides a clear explanation of the mass-balance–based mathematical modelling of bioprocesses and the main tools for its dynamic analysis Offers industry-based applications on: myco-diesel for implementing "quality" of observability; developing a virtual sensor based on the Just-In-Time Model to monitor biological control systems; and virtual sensor design for state estimation in a photocatalytic bioreactor for hydrogen production Control in Bioengineering and Bioprocessing is intended as a foundational text for graduate level students in bioengineering, as well as a reference text for researchers, engineers, and other practitioners interested in the field of estimation and control of bioprocesses.

Control Theory and Systems Biology

Control Theory and Systems Biology
Author: Pablo A. Iglesias,Brian P. Ingalls
Publsiher: MIT Press
Total Pages: 345
Release: 2010
ISBN 10: 0262013347
ISBN 13: 9780262013345
Language: EN, FR, DE, ES & NL

Control Theory and Systems Biology Book Review:

A survey of how engineering techniques from control and systems theory can be used tohelp biologists understand the behavior of cellular systems.

Application of Biomedical Engineering in Neuroscience

Application of Biomedical Engineering in Neuroscience
Author: Sudip Paul
Publsiher: Springer Nature
Total Pages: 490
Release: 2019-11-19
ISBN 10: 9811371423
ISBN 13: 9789811371424
Language: EN, FR, DE, ES & NL

Application of Biomedical Engineering in Neuroscience Book Review:

This book focuses on interdisciplinary research in the field of biomedical engineering and neuroscience. Biomedical engineering is a vast field, ranging from bioengineering to brain-computer interfaces. The book explores the system-level function and dysfunction of the nervous system from scientific and engineering perspectives. The initial sections introduce readers to the physiology of the brain, and to the biomedical tools needed for diagnostics and effective therapies for various neurodegenerative and regenerative disorders. In turn, the book summarizes the biomedical interventions that are used to understand the neural mechanisms underlying empathy disorders, and reviews recent advances in biomedical engineering for rehabilitation in connection with neurodevelopmental disorders and brain injuries. Lastly, the book discusses innovations in machine learning and artificial intelligence for computer-aided disease diagnosis and treatment, as well as applications of nanotechnology in therapeutic neurology.

Signals and Systems Analysis In Biomedical Engineering

Signals and Systems Analysis In Biomedical Engineering
Author: Robert B. Northrop
Publsiher: CRC Press
Total Pages: 654
Release: 2016-04-19
ISBN 10: 1439812535
ISBN 13: 9781439812532
Language: EN, FR, DE, ES & NL

Signals and Systems Analysis In Biomedical Engineering Book Review:

The first edition of this text, based on the author's 30 years of teaching and research on neurosensory systems, helped biomedical engineering students and professionals strengthen their skills in the common network of applied mathematics that ties together the diverse disciplines that comprise this field. Updated and revised to include new materia

Biomedical Engineering and Information Systems Technologies Tools and Applications

Biomedical Engineering and Information Systems  Technologies  Tools and Applications
Author: Shukla, Anupam,Tiwari, Ritu
Publsiher: IGI Global
Total Pages: 384
Release: 2010-07-31
ISBN 10: 161692005X
ISBN 13: 9781616920050
Language: EN, FR, DE, ES & NL

Biomedical Engineering and Information Systems Technologies Tools and Applications Book Review:

"Bridging the disciplines of engineering and medicine, this book informs researchers, clinicians, and practitioners of the latest developments in diagnostic tools, decision support systems, and intelligent devices that impact and redefine research in and delivery of medical services"--Provided by publisher.

Handbook of Research on Advanced Intelligent Control Engineering and Automation

Handbook of Research on Advanced Intelligent Control Engineering and Automation
Author: Azar, Ahmad Taher
Publsiher: IGI Global
Total Pages: 795
Release: 2014-11-30
ISBN 10: 1466672498
ISBN 13: 9781466672499
Language: EN, FR, DE, ES & NL

Handbook of Research on Advanced Intelligent Control Engineering and Automation Book Review:

In industrial engineering and manufacturing, control of individual processes and systems is crucial to developing a quality final product. Rapid developments in technology are pioneering new techniques of research in control and automation with multi-disciplinary applications in electrical, electronic, chemical, mechanical, aerospace, and instrumentation engineering. The Handbook of Research on Advanced Intelligent Control Engineering and Automation presents the latest research into intelligent control technologies with the goal of advancing knowledge and applications in various domains. This text will serve as a reference book for scientists, engineers, and researchers, as it features many applications of new computational and mathematical tools for solving complicated problems of mathematical modeling, simulation, and control.

Modeling and Simulation in Biomedical Engineering Applications in Cardiorespiratory Physiology

Modeling and Simulation in Biomedical Engineering  Applications in Cardiorespiratory Physiology
Author: Willem van Meurs
Publsiher: McGraw Hill Professional
Total Pages: 224
Release: 2011-08-07
ISBN 10: 0071714464
ISBN 13: 9780071714464
Language: EN, FR, DE, ES & NL

Modeling and Simulation in Biomedical Engineering Applications in Cardiorespiratory Physiology Book Review:

THEORY AND PRACTICE OF MODELING AND SIMULATING HUMAN PHYSIOLOGY Written by a coinventor of the Human Patient Simulator (HPS) and past president of the Society in Europe for Simulation Applied to Medicine (SESAM), Modeling and Simulation in Biomedical Engineering: Applications in Cardiorespiratory Physiology is a compact and consistent introduction to this expanding field. The book divides the modeling and simulation process into five manageable steps--requirements, conceptual models, mathematical models, software implementation, and simulation results and validation. A framework and a basic set of deterministic, continuous-time models for the cardiorespiratory system are provided. This timely resource also addresses advanced topics, including sensitivity analysis and setting model requirements as part of an encompassing simulation and simulator design. Practical examples provide you with the skills to evaluate and adapt existing physiologic models or create new ones for specific applications. Coverage includes: Signals and systems Model requirements Conceptual models Mathematical models Software implementation Simulation results and model validation Cardiorespiratory system model Circulation Respiration Physiologic control Sensitivity analysis of a cardiovascular model Design of model-driven acute care training simulators “Uniquely qualified to author such a text, van Meurs is one of the original developers of CAE Healthcare’s Human Patient Simulator (HPS). ...His understanding of mathematics, human physiology, pharmacology, control systems, and systems engineering, combined with a conversational writing style, results in a readable text. ...The ample illustrations and tables also break up the text and make reading the book easier on the eyes. ...concise yet in conversational style, with real-life examples. This book is highly recommended for coursework in physiologic modeling and for all who are interested in simulator design and development. The book pulls all these topics together under one cover and is an important contribution to biomedical literature.” --IEEE Pulse, January 2014 “This book is written by a professional engineer who is unique in that he seems to have a natural understanding of 3 key areas as follows: the hardware involved with simulators, human physiology, and mathematical modeling. Willem van Meurs is one of the inventors of the model-driven human patient simulator (HPS), and so, he is very qualified to write this book. The book is written in a clear way, using the first person throughout, in a conversational manner, with a style that involves posing questions and answering them in subsequent text. ...The book starts with a very useful introduction and background chapter, setting out the scene for the rest of the book. ...I have used his book in enhancing my own talks and understanding human patient simulation and can strongly recommend it.” --Simulation in Healthcare December, 2012 Reviewed by Mark A. Tooley, Ph.D., Department of Medical Physics and Bioengineering, Royal United Hospital, Combe Park, Bath, UK.