Conjugate Addition Reactions in Organic Synthesis

Conjugate Addition Reactions in Organic Synthesis
Author: P. Perlmutter
Publsiher: Elsevier
Total Pages: 394
Release: 2013-10-22
ISBN 10: 1483293785
ISBN 13: 9781483293783
Language: EN, FR, DE, ES & NL

Conjugate Addition Reactions in Organic Synthesis Book Review:

This book provides an introduction to the chemistry of conjugate reactions, a group of reactions that constitute one of the most important classes of chemical reactions in organic synthesis. The book is organised in terms of the major classes of conjugate acceptors. Within each of these classes, the chemistry and applications of conjugate additions with several different categories of nucleophiles have been examined. Where several different nucleophiles achieve the same synthetic transformation, they are cross-referenced within the book and qualitative comparisons offered where appropriate. Examples of the use of conjugate additions in total synthesis of important molecules are included, with a special emphasis throughout the book on stereoselectivity. This will be a useful main text for graduate and postgraduate courses on conjugate addition reactions or the Michael reaction. It could also serve as a supplementary text for courses on topics such as the chemistry of organocopper reagents, enamines and carbanion chemistry.

Conjugate Addition Reactions in Organic Synthesis

Conjugate Addition Reactions in Organic Synthesis
Author: Patrick Perlmutter
Publsiher: Elsevier
Total Pages: 512
Release: 2020-12-29
ISBN 10: 9780128186282
ISBN 13: 0128186283
Language: EN, FR, DE, ES & NL

Conjugate Addition Reactions in Organic Synthesis Book Review:

Conjugate Addition Reactions in Organic Synthesis, second edition, provides an introduction to the chemistry of conjugate reactions, a group of reactions that constitute one of the most important classes of chemical reactions in organic synthesis. The book is organized according to class of acceptor rather than the class of nucleophile, which makes for easier synthetic problem solving. All aspects of conjugate addition reactions are covered, including theory, mechanism, catalysis, and total synthesis. Asymmetric processes are featured heavily, and there is emphasis on catalysis, given its importance in all aspects of organic synthesis today. Extensive examples in total synthesis illustrate how particular synthetic challenges are addressed and resolved with conjugate addition chemistry. The second edition features new coverage of acceptors and nucleophiles, as well as organocatalysis, gold catalysis, peptide catalysis, arene additions, and emerging areas such as biocatalytic methods and advances in mechanism theory. This book is an ideal reference for advanced undergraduates, post-graduates, researchers, and academics working in medicinal, pharmaceutical, polymer and industrial chemistry. Features a unique structure for this subject which enables readers to readily access information based on specific classes of conjugate acceptor Provides a thorough account of the latest thinking of the mechanistic basis of conjugate addition reactions and all the latest - and best - methods for achieving the highest selectivity in conjugate addition reactions Includes over 200 examples of total synthesis illustrating how particular synthetic challenges are addressed and resolved with conjugate addition chemistry Covers an up to date treatment of the latest aspects of conjugate addition reactions including inter alia, cascade reactions, organocatalysis and flow chemistry

Organocatalytic Enantioselective Conjugate Addition Reactions

Organocatalytic Enantioselective Conjugate Addition Reactions
Author: Jose L. Vicario
Publsiher: Royal Society of Chemistry
Total Pages: 354
Release: 2010
ISBN 10: 1849730245
ISBN 13: 9781849730242
Language: EN, FR, DE, ES & NL

Organocatalytic Enantioselective Conjugate Addition Reactions Book Review:

This book, unique in its field, is a comprehensive description of all the methodologies reported for carrying out conjugate addition reactions in a stereoselective way, using small chiral organic molecules as catalysts (organocatalysts). In the last 3-4 years, this has been a rapidly growing field in organic chemistry, and many papers have appeared reporting excellent protocols for carrying out these highly efficient transformations that compete well with other classical approachse using transition metal catalysts. A particularly attractive feature of this transformation relies upon the fact that the conjugate addition (Michael and Hetero-Michael reactions) is an extraoridinarily effective means to initiate cascade processes which result in the formation of complex molecules from very small and simple starting blocks. The book, written by noted experts, covers all recent advances in this not topic, and provides a good state-of-the-art review for organic chemists working in this field and all those who wish to start projects in this area. The Series is intended to provide an accessible reference for postgraduates and industrialists working in the field of catalysis and its applications. Books will be produced either as monographs or reference handbooks. The Series will cover research developments and applications of catalysis, in both academia and industry.

Modern Methods of Organic Synthesis

Modern Methods of Organic Synthesis
Author: W. Carruthers,Iain Coldham
Publsiher: Cambridge University Press
Total Pages: 493
Release: 2004-10-14
ISBN 10: 9780521778305
ISBN 13: 0521778301
Language: EN, FR, DE, ES & NL

Modern Methods of Organic Synthesis Book Review:

Textbook on modern methods of organic synthesis.

Stereoselective Multiple Bond-Forming Transformations in Organic Synthesis

Stereoselective Multiple Bond-Forming Transformations in Organic Synthesis
Author: Jean Rodriguez,Damien Bonne
Publsiher: John Wiley & Sons
Total Pages: 400
Release: 2015-05-04
ISBN 10: 1118672712
ISBN 13: 9781118672716
Language: EN, FR, DE, ES & NL

Stereoselective Multiple Bond-Forming Transformations in Organic Synthesis Book Review:

Catalysis in Asymmetric Synthesis

Catalysis in Asymmetric Synthesis
Author: Vittorio Caprio,Jonathan Williams
Publsiher: John Wiley & Sons
Total Pages: 393
Release: 2009-03-09
ISBN 10: 1405190914
ISBN 13: 9781405190916
Language: EN, FR, DE, ES & NL

Catalysis in Asymmetric Synthesis Book Review:

Written from a synthetic organic chemistry perspective, this is a highly practical and relevant text for undergraduates, postgraduates and industrial organic chemists.

Cycloaddition Reactions in Organic Synthesis

Cycloaddition Reactions in Organic Synthesis
Author: W. Carruthers
Publsiher: Elsevier
Total Pages: 382
Release: 2013-10-22
ISBN 10: 008091232X
ISBN 13: 9780080912325
Language: EN, FR, DE, ES & NL

Cycloaddition Reactions in Organic Synthesis Book Review:

Demonstrates the wide scope of cycloaddition reactions, including the Diels-Alder reaction, the ene reaction, 1,3-dipolar cycloadditions and [2+2] cycloadditions in organic synthesis. The author, a leading exponent of the subject, illustrates the ways in which they can be employed in the synthesis of a wide range of carbocyclic and heterocyclic compounds, including a variety of natural products of various types. Special attention is given to intramolecular reactions, which often provide a rapid and efficient route to polycyclic compounds, and to the stereochemistry of the reactions, including recent and developing work on enantioselective synthesis.

The Chemistry of Organocopper Compounds

The Chemistry of Organocopper Compounds
Author: Zvi Rappoport,Ilan Marek
Publsiher: John Wiley & Sons
Total Pages: 1178
Release: 2010-01-07
ISBN 10: 0470772964
ISBN 13: 9780470772966
Language: EN, FR, DE, ES & NL

The Chemistry of Organocopper Compounds Book Review:

Copper in organic synthesis has seen a tremendous development over the past ten years. This text represents the most comprehensive survey on the use of Copper and Cuprates in organic synthesis. The first time that the Patai Series touches on Copper compounds, it contains contributions by leading experts, and delivers the quality expected from the Patai Series.

Methods of Non-α-Amino Acid Synthesis, Second Edition

Methods of Non-α-Amino Acid Synthesis, Second Edition
Author: Michael Bryant Smith
Publsiher: CRC Press
Total Pages: 242
Release: 2013-10-23
ISBN 10: 1466577924
ISBN 13: 9781466577923
Language: EN, FR, DE, ES & NL

Methods of Non-α-Amino Acid Synthesis, Second Edition Book Review:

Although less common than α-amino acids, non-α-amino acids—where the amino group is not on the carbon immediately adjacent to the carboxyl group but is attached to another carbon in the chain (for example, the β, γ, δ carbon)—are components of biologically important molecules, are significant in the pharmaceutical industry, and are useful starting materials for many areas of organic chemistry. Since the publication of the first edition of this book nearly 20 years ago, synthetic work devoted to the preparation of non- α-amino acids has expanded greatly. Methods of Non-α-Amino Acid Synthesis, Second Edition has been extensively rewritten and reorganized, providing an up-to-date review of strategies and methods for non-α-amino acid synthesis, particularly those amino acids that are key synthetic intermediates or important compounds in their own right. It focuses on acyclic amino acids of C3–C10, but also aminoalkanoic carboxylic acids, aminoalkenoic acids, and aminoalkynoic acids. The new edition contains many updated references and has a greater emphasis on the biological importance of non-α-amino acids. In addition to an array of synthetic methods, the book offers discussions on why non-α-amino acids are important. The book covers synthetic methods that rely on substituent refunctionalization, the conversion of cyclic precursors to acyclic amino acids, conjugate addition reactions, and enolate anion reactions and condensation reactions that lead to non-α-amino acids. It also examines reactions and strategies that lead to good diastereoselectivity and enantioselectivity during synthesis. A chapter devoted to biologically important amino acids includes separate sections on GABA, GABOB, carnitine, DAVA, statine, and other significant amino acids as well as a new section on peptides and proteins that contain non-α-amino acids. The final chapter addresses aminocyclic and heterocyclic amino acids.

Modern Organocopper Chemistry

Modern Organocopper Chemistry
Author: Norbert Krause
Publsiher: John Wiley & Sons
Total Pages: 377
Release: 2002
ISBN 10: 9783527297733
ISBN 13: 3527297731
Language: EN, FR, DE, ES & NL

Modern Organocopper Chemistry Book Review:

Organocopper compounds are now an integral part of every modern synthesis laboratory, yet a certain amount of experience is needed if they are to be used effectively. This manual, edited by Norbert Krause, contains all the useful tips and tricks about these reagents gained from personal experience. This allows those working in laboratories, in both academia and industry, to better utilize these effective synthesis tools.

Advanced Problems in Organic Reaction Mechanisms

Advanced Problems in Organic Reaction Mechanisms
Author: Anonim
Publsiher: Elsevier
Total Pages: 152
Release: 1997-12-04
ISBN 10: 9780080498775
ISBN 13: 0080498779
Language: EN, FR, DE, ES & NL

Advanced Problems in Organic Reaction Mechanisms Book Review:

The Elsevier Tetrahedron Organic Chemistry Series is a topical series of monographs by world-renowned scientists in several fields of organic chemistry. The Tetrahedron Organic Chemistry Series has been very successful in providing some of the very best scholarly works in these topical areas that have proven to be of lasting quality as indispensable reference sources. These books have provided the practicing researcher, student and scholar with an invaluable source of comprehensive reviews in organic chemistry, predominantly in the areas of synthesis and structure determination, including: * Reagents * Reaction mechanisms * Molecular Diversity * Asymmetric Synthesis * Multi-dimensional nmr * Enzymatic Synthesis * Organometallic Chemistry * Biologically Important Molecules

Organozinc Reagents in Organic Synthesis

Organozinc Reagents in Organic Synthesis
Author: Ender Erdik
Publsiher: CRC Press
Total Pages: 432
Release: 1996-06-05
ISBN 10: 9780849391514
ISBN 13: 0849391512
Language: EN, FR, DE, ES & NL

Organozinc Reagents in Organic Synthesis Book Review:

Organozinc reagents are used extensively in organic synthesis to find useful pathways to organic products. Illustrated and tabulated with over 950 equations, schemes, tables, and figures, Organozinc Reagents in Organic Synthesis provides an overall picture of the chemistry of organozinc compounds. Written by a professor of organic chemistry, the book familiarizes the reader with the reactions involving organozinc reagents that have general usefulness in synthesis. Emphasis is placed on preparation methods and reactivity of organozinc reagents. Reactions are summarized in equations and schemes, making it easy for you to see the characteristics of each type of reaction.

Iron Catalysis in Organic Chemistry

Iron Catalysis in Organic Chemistry
Author: Bernd Plietker
Publsiher: John Wiley & Sons
Total Pages: 295
Release: 2008-09-08
ISBN 10: 3527623280
ISBN 13: 9783527623280
Language: EN, FR, DE, ES & NL

Iron Catalysis in Organic Chemistry Book Review:

This first comprehensive book to cover this exciting field also deals with the biological aspects, such as enzymes with iron. Following an introduction, this handy reference and handbook goes on to deal with reductions, oxidations of C, H- and C=C bonds, oxidative allylic oxygenation and amination, the oxidation of heteroatoms, cross coupling reactions, aromatic and nucleophilic substitutions, addition to carbonyl compounds, and cyclisations as well as ring opening reactions. The chapters are clearly classified according to the reaction type, allowing readers to quickly locate the desired information.

Catalytic Asymmetric Conjugate Reactions

Catalytic Asymmetric Conjugate Reactions
Author: Armando Cordova
Publsiher: John Wiley & Sons
Total Pages: 464
Release: 2010-12-01
ISBN 10: 9783527632091
ISBN 13: 3527632093
Language: EN, FR, DE, ES & NL

Catalytic Asymmetric Conjugate Reactions Book Review:

This unique and long-awaited handbook on this important topic in the hot field of stereoselective organic synthesis covers several types of nucleophiles. Top international authors deal with modern forms of achieving stereoselective conjugate additions based on the use of chiral auxiliaries or asymmetric catalysis, such as P-N ligands, organocatalysis, domino reactions, Lewis acid and base catalysis. There is also a discussion of the employment of enantioselective conjugate addition transformations in total synthesis of important molecules. With its reliable and previously unpublished experimental procedures, this is a true source of high quality information.

Some Modern Methods of Organic Synthesis

Some Modern Methods of Organic Synthesis
Author: W. Carruthers
Publsiher: CUP Archive
Total Pages: 399
Release: 1971-10-31
ISBN 10: 9780521096430
ISBN 13: 052109643X
Language: EN, FR, DE, ES & NL

Some Modern Methods of Organic Synthesis Book Review:

Organolithiums in Enantioselective Synthesis

Organolithiums in Enantioselective Synthesis
Author: David M. Hodgson,Peter Andrew Beak
Publsiher: Springer Science & Business Media
Total Pages: 320
Release: 2003-04-30
ISBN 10: 3540001042
ISBN 13: 9783540001041
Language: EN, FR, DE, ES & NL

Organolithiums in Enantioselective Synthesis Book Review:

with contributions by numerous experts

Organic Reactions

Organic Reactions
Author: Scott E. Denmark
Publsiher: John Wiley & Sons
Total Pages: 952
Release: 2016-06-20
ISBN 10: 111928144X
ISBN 13: 9781119281443
Language: EN, FR, DE, ES & NL

Organic Reactions Book Review:

The latest volume in this series for organic chemists in industry presents critical discussions of widely used organic reactions or particular phases of a reaction. The material is treated from a preparative viewpoint, with emphasis on limitations, interfering influences, effects of structure and the selection of experimental techniques. The work includes tables that contain all possible examples of the reaction under consideration. Detailed procedures illustrate the significant modifications of each method.

The Nitro Group in Organic Synthesis

The Nitro Group in Organic Synthesis
Author: Noboru Ono
Publsiher: John Wiley & Sons
Total Pages: 392
Release: 2003-05-08
ISBN 10: 9780471458463
ISBN 13: 0471458465
Language: EN, FR, DE, ES & NL

The Nitro Group in Organic Synthesis Book Review:

The most useful reactions of organonitro compounds in organic synthesis Compounds containing nitro groups are useful intermediates for the synthesis of natural products and other complex organic molecules. The Nitro Group in Organic Synthesis focuses on reactions that proceed under mild conditions, important functional groups that can be synthesized by conversion of nitro groups, and the stereoselectivity of reactions of nitro compounds. These issues are of great importance to practicing researchers in today's pharmaceutical, agrochemical, and fine chemical industries. The Nitro Group in Organic Synthesis also emphasizes environmentally-friendly methods for nitration, the importance of aliphatic nitro compounds, and modern preparation of nitro compounds. Other topics discussed include: * Henry reaction * Asymmetric Michael addition * Alkylation, acylation, halogenation, and related reactions of RNO2 * Substitution and elimination of NO2 and RNO2 The Nitro Group in Organic Synthesis is a useful resource for researchers and students in organic and medicinal chemistry.

Comprehensive Organic Synthesis: Additions to and substitutions at C-C[pi]-Bonds

Comprehensive Organic Synthesis: Additions to and substitutions at C-C[pi]-Bonds
Author: Barry M. Trost,M.F. Semmelhack,Ian Fleming
Publsiher: Elsevier
Total Pages: 1299
Release: 1991
ISBN 10: 9780080405957
ISBN 13: 0080405959
Language: EN, FR, DE, ES & NL

Comprehensive Organic Synthesis: Additions to and substitutions at C-C[pi]-Bonds Book Review:

Volume 4 focuses on additions and the resulting substitutions at carbon-carbon &pgr;-bonds. Part 1 includes processes generally considered as simple polar reactions, reactive electrophiles and nucleophiles adding to alkenes and alkynes. A major topic is Michael-type addition to electron deficient &pgr;-bonds, featured in the first six chapters. In part 2 are collected the four general processes leading to nucleophilic aromatic substitution, including radical chain processes and transition metal activation through to &pgr;-complexation. Metal-activated addition (generally by nucleophiles) to alkenes and polyenes is presented in part 3, including allylic alkylation catalyzed by palladium. The coverage of nonpolar additions in part 4 includes radical additions, organometal addition (Heck reaction), carbene addition, and 1,3-dipolar cycloadditions.

Basic principles of organic chemistry

Basic principles of organic chemistry
Author: John D. Roberts,Marjorie C. Caserio
Publsiher: Anonim
Total Pages: 596
Release: 1979
ISBN 10:
ISBN 13: OCLC:927630476
Language: EN, FR, DE, ES & NL

Basic principles of organic chemistry Book Review: