Conceptual Breakthroughs in the Evolutionary Biology of Aging

Conceptual Breakthroughs in the Evolutionary Biology of Aging
Author: Kenneth R. Arnold,Michael R. Rose
Publsiher: Academic Press
Total Pages: 296
Release: 2021-06-01
ISBN 10: 0128215461
ISBN 13: 9780128215463
Language: EN, FR, DE, ES & NL

Conceptual Breakthroughs in the Evolutionary Biology of Aging Book Review:

Conceptual Breakthroughs in the Evolutionary Biology of Aging continues the innovative Conceptual Breakthroughs series by providing a comprehensive outline of the major breakthroughs that built the evolutionary biology of aging as a leading scientific field. Following the evolutionary study of aging from its humble origins to the present, the book's chapters treat the field’s breakthroughs one at a time. Users will find a concise and accessible analysis of the science of aging viewed through an evolutionary lens. Building upon widely-cited studies conducted by author Michael Rose, this book covers 30 subsequent years of growth and development within the field. The book highlights key publications for those who are not experts in the field, providing an important resource for researchers. Given the prevailing interest in changing the aging process dramatically, it is a powerful tool for readers who have a vested interest in understanding its causes and future control measures. Reviews cell-molecular theories of aging in the light of evolutionary biology Offers an evolutionary analysis of prospects for mitigating aging not commonly discussed within private and public sectors Provides readers with a radically different perspective on contemporary biological gerontology, specifically through the lens of evolutionary biology

Conceptual Breakthroughs in Evolutionary Ecology

Conceptual Breakthroughs in Evolutionary Ecology
Author: Laurence Mueller
Publsiher: Academic Press
Total Pages: 204
Release: 2019-11-25
ISBN 10: 0128160144
ISBN 13: 9780128160145
Language: EN, FR, DE, ES & NL

Conceptual Breakthroughs in Evolutionary Ecology Book Review:

Although biologists recognize evolutionary ecology by name, many only have a limited understanding of its conceptual roots and historical development. Conceptual Breakthroughs in Evolutionary Ecology fills that knowledge gap in a thought-provoking and readable format. Written by a world-renowned evolutionary ecologist, this book embodies a unique blend of expertise in combining theory and experiment, population genetics and ecology. Following an easily-accessible structure, this book encapsulates and chronologizes the history behind evolutionary ecology. It also focuses on the integration of age-structure and density-dependent selection into an understanding of life-history evolution. Covers over 60 seminal breakthroughs and paradigm shifts in the field of evolutionary biology and ecology Modular format permits ready access to each described subject Historical overview of a field whose concepts are central to all of biology and relevant to a broad audience of biologists, science historians, and philosophers of science

Evolutionary Biology of Aging

Evolutionary Biology of Aging
Author: Michael R. Rose
Publsiher: Oxford University Press on Demand
Total Pages: 221
Release: 1991
ISBN 10: 0195095308
ISBN 13: 9780195095302
Language: EN, FR, DE, ES & NL

Evolutionary Biology of Aging Book Review:

In this provocative book on the process of growing old, Michael Rose goes right to the heart of the fundamental "unsolved problem" of biology. Why do we grow old? The proposed theory is that to understand aging we must understand its evolution; only then do its taxonomic distribution and its genetic and physiological mechanisms become intelligible. Evidence is produced from the fields of cell biology, physiology, and gerontology.

Conceptual Breakthroughs in Evolutionary Genetics

Conceptual Breakthroughs in Evolutionary Genetics
Author: John C. Avise
Publsiher: Academic Press
Total Pages: 184
Release: 2014-01-18
ISBN 10: 0124202373
ISBN 13: 9780124202375
Language: EN, FR, DE, ES & NL

Conceptual Breakthroughs in Evolutionary Genetics Book Review:

Conceptual Breakthroughs in Evolutionary Genetics is a pithy, lively book occupying a special niche—the conceptual history of evolutionary genetics— not inhabited by any other available treatment. Written by a world-leading authority in evolutionary genetics, this work encapsulates and ranks 70 of the most significant paradigm shifts in evolutionary biology and genetics during the century-and-a-half since Darwin and Mendel. The science of evolutionary genetics is central to all of biology, but many students and other practitioners have little knowledge of its historical roots and conceptual developments. This book fills that knowledge gap in a thought-provoking and readable format. This fascinating chronological journey along the many conceptual pathways to our modern understanding of evolutionary and genetic principles is a wonderful springboard for discussions in undergraduate or graduate seminars in evolutionary biology and genetics. But more than that, anyone interested in the history and philosophy of science will find much of value between its covers. Provides a relative ranking of 70 seminal breakthroughs and paradigm shifts in the field of evolutionary biology and genetics Modular format permits ready access to each described subject Historical overview of a field whose concepts are central to all of biology and relevant to a broad audience of biologists, science historians, and philosophers of science Extensively cross-referenced with a guide to landmark papers and books for each topic

Biology of Aging

Biology of Aging
Author: Robert Arking
Publsiher: Oxford University Press
Total Pages: 604
Release: 2006-02-02
ISBN 10: 0195167392
ISBN 13: 9780195167399
Language: EN, FR, DE, ES & NL

Biology of Aging Book Review:

Robert Arking's Biology of Aging is an introductory text to the biology of aging which gives advanced undergraduate and graduate students a thorough review of the entire field. The mass of data related to aging is summarized into fifteen focused chapters, each dealing with some particular aspect of the problem. His prior two editions have also served admirably as a reference text for clinicians and scientists. This new edition captures the extraordinary recent advances in our knowledge of the ultimate and proximal mechanisms underlying the phenomenon of aging.

Handbook of the Biology of Aging

Handbook of the Biology of Aging
Author: Edward J. Masoro,Steven N. Austad
Publsiher: Elsevier
Total Pages: 680
Release: 2011-04-28
ISBN 10: 0080491405
ISBN 13: 9780080491400
Language: EN, FR, DE, ES & NL

Handbook of the Biology of Aging Book Review:

The Handbook of the Biology of Aging, Sixth Edition, provides a comprehensive overview of the latest research findings in the biology of aging. Intended as a summary for researchers, it is also adopted as a high level textbook for graduate and upper level undergraduate courses. The Sixth Edition is 20% larger than the Fifth Edition, with 21 chapters summarizing the latest findings in research on the biology of aging. The content of the work is virtually 100% new. Though a selected few topics are similar to the Fifth Edition, these chapters are authored by new contributors with new information. The majority of the chapters are completely new in both content and authorship. The Sixth Edition places greater emphasis and coverage on competing and complementary theories of aging, broadening the discussion of conceptual issues. Greater coverage of techniques used to study biological issues of aging include computer modeling, gene profiling, and demographic analyses. Coverage of research on Drosophilia is expanded from one chapter to four. New chapters on mammalian models discuss aging in relation to skeletal muscles, body fat and carbohydrate metabolism, growth hormone, and the human female reproductive system. Additional new chapters summarize exciting research on stem cells and cancer, dietary restriction, and whether age related diseases are an integral part of aging. The Handbook of the Biology of Aging, Sixth Edition is part of the Handbooks on Aging series, including Handbook of the Psychology of Aging and Handbook of Aging and the Social Sciences, also in their 6th editions.

Does Aging Stop

Does Aging Stop
Author: Laurence D. Mueller,Casandra L. Rauser,Michael R. Rose
Publsiher: OUP USA
Total Pages: 204
Release: 2011-07-29
ISBN 10: 0199754225
ISBN 13: 9780199754229
Language: EN, FR, DE, ES & NL

Does Aging Stop Book Review:

Does Aging Stop? shatters the conventional beliefs on which aging research has been based for the last fifty years.

Teaching About Evolution and the Nature of Science

Teaching About Evolution and the Nature of Science
Author: National Academy of Sciences,Division of Behavioral and Social Sciences and Education,Board on Science Education,Working Group on Teaching Evolution
Publsiher: National Academies Press
Total Pages: 150
Release: 1998-05-06
ISBN 10: 0309063647
ISBN 13: 9780309063647
Language: EN, FR, DE, ES & NL

Teaching About Evolution and the Nature of Science Book Review:

Today many school students are shielded from one of the most important concepts in modern science: evolution. In engaging and conversational style, Teaching About Evolution and the Nature of Science provides a well-structured framework for understanding and teaching evolution. Written for teachers, parents, and community officials as well as scientists and educators, this book describes how evolution reveals both the great diversity and similarity among the Earth's organisms; it explores how scientists approach the question of evolution; and it illustrates the nature of science as a way of knowing about the natural world. In addition, the book provides answers to frequently asked questions to help readers understand many of the issues and misconceptions about evolution. The book includes sample activities for teaching about evolution and the nature of science. For example, the book includes activities that investigate fossil footprints and population growth that teachers of science can use to introduce principles of evolution. Background information, materials, and step-by-step presentations are provided for each activity. In addition, this volume: Presents the evidence for evolution, including how evolution can be observed today. Explains the nature of science through a variety of examples. Describes how science differs from other human endeavors and why evolution is one of the best avenues for helping students understand this distinction. Answers frequently asked questions about evolution. Teaching About Evolution and the Nature of Science builds on the 1996 National Science Education Standards released by the National Research Council--and offers detailed guidance on how to evaluate and choose instructional materials that support the standards. Comprehensive and practical, this book brings one of today's educational challenges into focus in a balanced and reasoned discussion. It will be of special interest to teachers of science, school administrators, and interested members of the community.

Physiological Basis of Aging and Geriatrics Fourth Edition

Physiological Basis of Aging and Geriatrics  Fourth Edition
Author: Paola S. Timiras
Publsiher: CRC Press
Total Pages: 536
Release: 2007-08-16
ISBN 10: 9781420007091
ISBN 13: 1420007092
Language: EN, FR, DE, ES & NL

Physiological Basis of Aging and Geriatrics Fourth Edition Book Review:

Extensively revised and updated to reflect the current state of knowledge in the study of aging, this Fourth Edition offers a complete profile of the aging process at all levels, from molecules and cells to demography and evolution. Written by international experts in current basic and clinical aging research, this text includes aspects of individual, comparative, and differential aging, and discussions of theories and mechanisms of aging. This invaluable reference illustrates how bodily systems, organs, and functions are affected with aging, describes how genetic and environmental factors influence age-related changes, and addresses some of the clinical consequences of these changes for health and longevity. Well illustrated, with numerous tables and graphs, this book presents up-to-date information from internationally renowned experts in various bio-medical fields. New updated information includes: emphasis on emerging technologies and recent advances in biology and bioengineering that allow greater and longer independence of the elderly recent therapeutic developments in key diseases such as Alzheimer's, osteopenia, osteoporosis, high cholesterol, diabetes, gastritis, sexual impotence, and using transgenic animals as models of aging evaluation of the latest knowledge on the roles of oxidants and antioxidants, and correlates them with other aging-based theories expanded discussion of nutrition and physical exercise chapters on gene and stem cell interventions related to the aging process updated tables to reflect current trends, new research data, and up-to-date statistical information

Chasing Methuselah

Chasing Methuselah
Author: Todd T. W. Daly
Publsiher: Wipf and Stock Publishers
Total Pages: 324
Release: 2021-02-04
ISBN 10: 153269802X
ISBN 13: 9781532698026
Language: EN, FR, DE, ES & NL

Chasing Methuselah Book Review:

The quest to live much longer has moved from legend to the laboratory. Recent breakthroughs in genetics and pharmacology have put humanity on the precipice of slowing down human aging to extend the healthy life span. The promise of longer, healthier life is enormously attractive, and poses several challenging questions for Christians. Who wouldn't want to live 120 years or more before dying quickly? How do we make sense of human aging in light of Jesus' invitation to daily take up our crosses with the promise of the resurrection to come? Is there anything wrong with manipulating our bodies technologically to live longer? If so, how long is too long? Should aging itself be treated as a disease? In Chasing Methuselah, Todd Daly examines the modern biomedical anti-aging project from a Christian perspective, drawing on the ancient wisdom of the Desert Fathers, who believed that the incarnation opened a way for human life to regain the longevity of Adam and the biblical patriarchs through prayer and fasting. Daly balances these insights with the christological anthropology of Karl Barth, discussing the implications for human finitude, fear of death, and the use of anti-aging technology, weaving a path between outright condemnation and uncritical enthusiasm.

Does Aging Stop

Does Aging Stop
Author: Laurence D. Mueller,Casandra L. Rauser,Michael R. Rose
Publsiher: Oxford University Press
Total Pages: 224
Release: 2011-07-29
ISBN 10: 0190454105
ISBN 13: 9780190454104
Language: EN, FR, DE, ES & NL

Does Aging Stop Book Review:

Does Aging Stop? reveals the most paradoxical finding of recent aging research: the cessation of demographic aging. The authors show that aging stops at the level of the individual organism, and explain why evolution allows this. The implications of this counter-intuitive conclusion are profound, and aging research now needs to accept three uncomfortable truths. First, aging is not a cumulative physiological process. Second, the fundamental theory that is required to explain, manipulate, and probe the phenomena of aging comes from evolutionary biology. Third, strong-inference experimental strategies for aging must be founded in evolutionary research, not cell or molecular biology. The result of fifteen years of research bringing together new applications of evolutionary theory, new models for demography, and massive experimentation, Does Aging Stop? advances an entirely new foundation for the scientific study of aging.

Preparing for an Aging World

Preparing for an Aging World
Author: National Research Council,Division of Behavioral and Social Sciences and Education,Commission on Behavioral and Social Sciences and Education,Committee on National Statistics,Committee on Population,Panel on a Research Agenda and New Data for an Aging World
Publsiher: National Academies Press
Total Pages: 328
Release: 2001-06-26
ISBN 10: 9780309170871
ISBN 13: 0309170877
Language: EN, FR, DE, ES & NL

Preparing for an Aging World Book Review:

Aging is a process that encompasses virtually all aspects of life. Because the speed of population aging is accelerating, and because the data needed to study the aging process are complex and expensive to obtain, it is imperative that countries coordinate their research efforts to reap the most benefits from this important information. Preparing for an Aging World looks at the behavioral and socioeconomic aspects of aging, and focuses on work, retirement, and pensions; wealth and savings behavior; health and disability; intergenerational transfers; and concepts of well-being. It makes recommendations for a collection of new, cross-national data on aging populationsâ€"data that will allow nations to develop policies and programs for addressing the major shifts in population age structure now occurring. These efforts, if made internationally, would advance our understanding of the aging process around the world.

The Aging Mind

The Aging Mind
Author: National Research Council,Division of Behavioral and Social Sciences and Education,Board on Behavioral, Cognitive, and Sensory Sciences,Committee on Future Directions for Cognitive Research on Aging
Publsiher: National Academies Press
Total Pages: 288
Release: 2000-04-18
ISBN 10: 9780309172196
ISBN 13: 0309172195
Language: EN, FR, DE, ES & NL

The Aging Mind Book Review:

Possible new breakthroughs in understanding the aging mind that can be used to benefit older people are now emerging from research. This volume identifies the key scientific advances and the opportunities they bring. For example, science has learned that among older adults who do not suffer from Alzheimer’s disease or other dementias, cognitive decline may depend less on loss of brain cells than on changes in the health of neurons and neural networks. Research on the processes that maintain neural health shows promise of revealing new ways to promote cognitive functioning in older people. Research is also showing how cognitive functioning depends on the conjunction of biology and culture. The ways older people adapt to changes in their nervous systems, and perhaps the changes themselves, are shaped by past life experiences, present living situations, changing motives, cultural expectations, and emerging technology, as well as by their physical health status and sensory-motor capabilities. Improved understanding of how physical and contextual factors interact can help explain why some cognitive functions are impaired in aging while others are spared and why cognitive capability is impaired in some older adults and spared in others. On the basis of these exciting findings, the report makes specific recommends that the U.S. government support three major new initiatives as the next steps for research.

Ageing and Technology

Ageing and Technology
Author: Emma Domínguez-Rué,Linda Nierling
Publsiher: transcript Verlag
Total Pages: 342
Release: 2016-01-31
ISBN 10: 3839429579
ISBN 13: 9783839429570
Language: EN, FR, DE, ES & NL

Ageing and Technology Book Review:

The booming increase of the senior population has become a social phenomenon and a challenge to our societies, and technological advances have undoubtedly contributed to improve the lives of elderly citizens in numerous aspects. In current debates on technology, however, the »human factor« is often largely ignored. The ageing individual is rather seen as a malfunctioning machine whose deficiencies must be diagnosed or as a set of limitations to be overcome by means of technological devices. This volume aims at focusing on the perspective of human beings deriving from the development and use of technology: this change of perspective - taking the human being and not technology first - may help us to become more sensitive to the ambivalences involved in the interaction between humans and technology, as well as to adapt technologies to the people that created the need for its existence, thus contributing to improve the quality of life of senior citizens.

Anti aging Drugs

Anti aging Drugs
Author: Alexander M Vaiserman
Publsiher: Royal Society of Chemistry
Total Pages: 570
Release: 2017-02-01
ISBN 10: 178262435X
ISBN 13: 9781782624356
Language: EN, FR, DE, ES & NL

Anti aging Drugs Book Review:

Aging is a natural phenomenon that is peculiar to all living things. However, accumulating findings indicate that senescence could be postponed or prevented by certain approaches. Substantial evidence has emerged supporting the possibility of radical human health and lifespan extension, in particular through pharmacological modulation of aging. A number of natural dietary ingredients and synthetic drugs have been assumed to have geroprotective potential. In the development of anti-aging therapeutics, several cell, insect, and animal models may provide useful starting points prior to human studies. This book provides an overview of current research aimed to search for life-extending medications and describes pharmacological aspects of anti-aging medicine. Readers are introduced to the fascinating historical background of geroprotection in the first chapter. In-depth information on models for investigating geroprotective drugs precedes a section covering anti-aging properties of pharmaceutical compounds, such as calorie restriction mimetics, autophagy inducers, senolytics and mitochondrial antioxidants. Finally, strategies to translate discoveries from aging research into drugs and healthcare policy perspectives on anti-ageing medicine are provided to give a complete picture of the field. A timely and carefully edited collection of chapters by leading researchers in the field, this book will be a fascinating and useful resource for pharmacologists, gerontologists and any scientifically interested person wishing to know more about the current status of research into anti-aging remedies, challenges and opportunities.

Lifespan

Lifespan
Author: David A. Sinclair,Matthew D. LaPlante
Publsiher: Atria Books
Total Pages: 432
Release: 2019-09-10
ISBN 10: 1501191977
ISBN 13: 9781501191978
Language: EN, FR, DE, ES & NL

Lifespan Book Review:

A NEW YORK TIMES BESTSELLER “Brilliant and enthralling.”​ —The Wall Street Journal A paradigm-shifting book from an acclaimed Harvard Medical School scientist and one of Time’s most influential people. It’s a seemingly undeniable truth that aging is inevitable. But what if everything we’ve been taught to believe about aging is wrong? What if we could choose our lifespan? In this groundbreaking book, Dr. David Sinclair, leading world authority on genetics and longevity, reveals a bold new theory for why we age. As he writes: “Aging is a disease, and that disease is treatable.” This eye-opening and provocative work takes us to the frontlines of research that is pushing the boundaries on our perceived scientific limitations, revealing incredible breakthroughs—many from Dr. David Sinclair’s own lab at Harvard—that demonstrate how we can slow down, or even reverse, aging. The key is activating newly discovered vitality genes, the descendants of an ancient genetic survival circuit that is both the cause of aging and the key to reversing it. Recent experiments in genetic reprogramming suggest that in the near future we may not just be able to feel younger, but actually become younger. Through a page-turning narrative, Dr. Sinclair invites you into the process of scientific discovery and reveals the emerging technologies and simple lifestyle changes—such as intermittent fasting, cold exposure, exercising with the right intensity, and eating less meat—that have been shown to help us live younger and healthier for longer. At once a roadmap for taking charge of our own health destiny and a bold new vision for the future of humankind, Lifespan will forever change the way we think about why we age and what we can do about it.

Evolutionary Biology

Evolutionary Biology
Author: Douglas J. Futuyma
Publsiher: Sinauer Associates, Incorporated
Total Pages: 600
Release: 1986
ISBN 10: 1928374650XXX
ISBN 13: UOM:39015007702866
Language: EN, FR, DE, ES & NL

Evolutionary Biology Book Review:

Covers the genetic, developmental, and ecological mechanisms of evolutionary change, the major features of evolutionary history as revealed by phylogenetic and paleontological studies, and material on adaptation, molecular evolution, co-evolution, and human evolution.

Above the Gene Beyond Biology

Above the Gene  Beyond Biology
Author: Jan Baedke
Publsiher: University of Pittsburgh Press
Total Pages: 296
Release: 2018-07-20
ISBN 10: 0822983400
ISBN 13: 9780822983408
Language: EN, FR, DE, ES & NL

Above the Gene Beyond Biology Book Review:

Epigenetics is currently one of the fastest-growing fields in the sciences. Epigenetic information not only controls DNA expression but links genetic factors with the environmental experiences that influence the traits and characteristics of an individual. What we eat, where we work, and how we live affects not only the activity of our genes but that of our offspring as well. This discovery has imposed a revolutionary theoretical shift on modern biology, especially on evolutionary theory. It has helped to uncover the developmental processes leading to cancer, obesity, schizophrenia, alcoholism, and aging, and to facilitate associated medial applications such as stem cell therapy and cloning. Above the Gene, Beyond Biology explores how biologists in this booming field investigate and explain living systems. Jan Baedke offers the first comprehensive philosophical discussion of epigenetic concepts, explanations, and methodologies so that we can better understand this “epigenetic turn” in the life sciences from a philosophical perspective.

Longevity

Longevity
Author: James R. Carey
Publsiher: Princeton University Press
Total Pages: 305
Release: 2021-01-12
ISBN 10: 0691224080
ISBN 13: 9780691224084
Language: EN, FR, DE, ES & NL

Longevity Book Review:

Despite our deep interest in mortality, little is known about why some individuals live to middle age and others to extreme old age. Life span, mortality, and aging present some of the most profound mysteries in biology. In Longevity, James Carey draws on unprecedented data to develop a biological and demographic framework for identifying the key factors that govern aging, life span, and mortality in humans and other animals. Carey presents the results of a monumental, twelve-year, National Institute on Aging-funded research project on the determinants of longevity using data from the life tables of five million Mediterranean fruit flies, the most comprehensive set of life table studies ever on the mortality dynamics of a single species. He interprets the fruit fly data within the context of human aging and the aging process in general to identify the determinants of mortality. Three key themes emerge: the absence of species-specific life span limits, the context-specific nature of the mortality rate, and biodemographic linkages between longevity and reproduction. A powerful foundation for the emerging field of biodemography and a rich framework for considering the future of human life span, Longevity will be an indispensable resource for readers from a range of fields including population biology, demography, gerontology, ecology, evolutionary biology, and medical research.

Advances in Geroscience

Advances in Geroscience
Author: Felipe Sierra,Ronald Kohanski
Publsiher: Springer
Total Pages: 622
Release: 2015-11-10
ISBN 10: 3319232460
ISBN 13: 9783319232461
Language: EN, FR, DE, ES & NL

Advances in Geroscience Book Review:

This book provides the first comprehensive overview of a new scientific discipline termed Geroscience. Geroscience examines the molecular and cellular mechanisms that might explain why aging is the main risk factor for most chronic diseases affecting the elderly population. Over the past few decades, researchers have made impressive progress in understanding the genetics, biology and physiology of aging. This book presents vital research that can help readers to better understand how aging is a critical malleable risk factor in most chronic diseases, which, in turn, could lead to interventions that can help increase a healthy lifespan, or ‘healthspan.’ The book begins with an analysis of the Geroscience hypothesis, as well as the epidemiological underpinnings that define aging as a candidate main risk factor for most chronic diseases. Next, each chapter focuses on one particular disease, or group of diseases, with an emphasis on how basic molecular and cellular biology might explain why aging is a major risk factor for it. Coverage in the book includes: cancer, cardiovascular disease, dementias, stroke, Parkinson's and Alzheimer’s diseases, osteoporosis, arthritis, diabetes asthma, emphysema, kidney disease, vision impairment, and AIDS/HIV. It finishes with a chapter on pain in the elderly and an overview of future steps needed to bring the newly acquired knowledge into the clinic and the public at large.