Conceptual Breakthroughs in the Evolutionary Biology of Aging

Conceptual Breakthroughs in the Evolutionary Biology of Aging
Author: Michael R. Rose,Kenneth Arnold
Publsiher: Academic Press
Total Pages: 296
Release: 2021-06-15
ISBN 10: 9780128215456
ISBN 13: 0128215453
Language: EN, FR, DE, ES & NL

Conceptual Breakthroughs in the Evolutionary Biology of Aging Book Review:

Conceptual Breakthroughs in the Evolutionary Biology of Aging continues the innovative Conceptual Breakthroughs series by providing a comprehensive outline of the major breakthroughs that built the evolutionary biology of aging as a leading scientific field. Following the evolutionary study of aging from its humble origins to its flourishing present, the chapters treat the field's breakthroughs one at a time. This book offers a concise and accessible analysis of the science of aging viewed through an evolutionary lens. Building upon widely-cited studies conducted by author Michael Rose, this book is unique in its coverage of the 30 subsequent years of growth and development within the field. The book highlights key publications for those who are not experts in the field. Conceptual Breakthroughs in the Evolutionary Biology of Aging provides an important resource for researchers. Given the prevailing interest changing the aging process dramatically, it is a powerful tool for readers who have a vested interest in understanding the causes so that they might work to control the scourge. Reviews cell-molecular theories of aging in the light of evolutionary biology Offers an evolutionary analysis of prospects for mitigating aging, which is not commonly discussed within private and public sectors Provides its readers with a radically different perspective on contemporary biological gerontology through the lens of evolutionary biology

Evolutionary Biology of Aging

Evolutionary Biology of Aging
Author: Michael R. Rose
Publsiher: Oxford University Press
Total Pages: 240
Release: 1994-10-27
ISBN 10: 9780198022725
ISBN 13: 0198022727
Language: EN, FR, DE, ES & NL

Evolutionary Biology of Aging Book Review:

This unique book looks at the biology of aging from a fundamentally new perspective, one based on evolutionary theory rather than traditional concepts which emphasize molecular and cellular processes. The basis for this approach lies in the fact that natural selection, as a powerful determining force, tends to decline in importance with age. Many of the characteristics we associate with aging, the author argues, are more the result of this decline than any mechanical imperative contained within organic structures. This theory in turn yields the most fruitful avenues for seeking answers to the problem of aging, and should be recognized as the intellectual core of gerontology and the foundation for future research. The author ably surveys the vast literature on aging, presenting mathematical, experimental, and comparative findings to illustrate and support the central thesis. The result is the first complete synthesis of this vital field. Evolutionary biologists, gerontologists, and all those concerned with the science of aging will find it a stimulating, strongly argued account.

Conceptual Breakthroughs in Evolutionary Ecology

Conceptual Breakthroughs in Evolutionary Ecology
Author: Laurence Mueller
Publsiher: Academic Press
Total Pages: 204
Release: 2019-11-25
ISBN 10: 0128160144
ISBN 13: 9780128160145
Language: EN, FR, DE, ES & NL

Conceptual Breakthroughs in Evolutionary Ecology Book Review:

Although biologists recognize evolutionary ecology by name, many only have a limited understanding of its conceptual roots and historical development. Conceptual Breakthroughs in Evolutionary Ecology fills that knowledge gap in a thought-provoking and readable format. Written by a world-renowned evolutionary ecologist, this book embodies a unique blend of expertise in combining theory and experiment, population genetics and ecology. Following an easily-accessible structure, this book encapsulates and chronologizes the history behind evolutionary ecology. It also focuses on the integration of age-structure and density-dependent selection into an understanding of life-history evolution. Covers over 60 seminal breakthroughs and paradigm shifts in the field of evolutionary biology and ecology Modular format permits ready access to each described subject Historical overview of a field whose concepts are central to all of biology and relevant to a broad audience of biologists, science historians, and philosophers of science

Conceptual Breakthroughs in Evolutionary Genetics

Conceptual Breakthroughs in Evolutionary Genetics
Author: John C. Avise
Publsiher: Academic Press
Total Pages: 184
Release: 2014-01-18
ISBN 10: 0124202373
ISBN 13: 9780124202375
Language: EN, FR, DE, ES & NL

Conceptual Breakthroughs in Evolutionary Genetics Book Review:

Conceptual Breakthroughs in Evolutionary Genetics is a pithy, lively book occupying a special niche—the conceptual history of evolutionary genetics— not inhabited by any other available treatment. Written by a world-leading authority in evolutionary genetics, this work encapsulates and ranks 70 of the most significant paradigm shifts in evolutionary biology and genetics during the century-and-a-half since Darwin and Mendel. The science of evolutionary genetics is central to all of biology, but many students and other practitioners have little knowledge of its historical roots and conceptual developments. This book fills that knowledge gap in a thought-provoking and readable format. This fascinating chronological journey along the many conceptual pathways to our modern understanding of evolutionary and genetic principles is a wonderful springboard for discussions in undergraduate or graduate seminars in evolutionary biology and genetics. But more than that, anyone interested in the history and philosophy of science will find much of value between its covers. Provides a relative ranking of 70 seminal breakthroughs and paradigm shifts in the field of evolutionary biology and genetics Modular format permits ready access to each described subject Historical overview of a field whose concepts are central to all of biology and relevant to a broad audience of biologists, science historians, and philosophers of science Extensively cross-referenced with a guide to landmark papers and books for each topic

Biology of Aging

Biology of Aging
Author: Robert Arking
Publsiher: Oxford University Press
Total Pages: 624
Release: 2006-02-02
ISBN 10: 9780199727629
ISBN 13: 0199727627
Language: EN, FR, DE, ES & NL

Biology of Aging Book Review:

Robert Arking's Biology of Aging, 3rd edition, is an introductory text to the biology of aging which gives advanced undergraduate and graduate students a thorough review of the entire field. His prior two editions have also served admirably as a reference text for clinicians and scientists. This new edition captures the extraordinary recent advances in our knowledge of the ultimate and proximal mechanisms underlying the phenomenon of aging. As a result, six important conceptual changes are included here: ? Clarified distinctions between the biological mechanisms involved in longevity determination and those involved in senescent processes. ? A new conceptual framework around which we can organize all the new facts about aging. This will assist readers to make sense of the information and use the data to form their own ideas. ? Increased knowledge of aging cells has lead to new ideas on how a cell transits from a healthy state to a senescent state, while still allowing for high levels of intra- and inter-specific variability. ? Discussion of senescent mechanisms assists the reader to understand that aging is a non-programmatic loss of function, likely arising from the loss of regulatory signals, and so is modifiable in the laboratory. ? Because the standard evolutionary story does not fully explain the evolution of social organisms, this edition also includes recent work dealing with intergenerational resource transfers. ? Lastly, if aging mechanisms are plastic, then the demand to move these anti-aging interventions into the human arena will inevitably grow. A discussion of the biological and ethical arguments on both sides of the question frames the question in an appropriate manner. The mass of data related to aging is summarized into fifteen focused chapters, each dealing with some particular aspect of the problem. The last two chapters integrate all this material into a coherent view of how the relevant biological processes change over the life span. This view is expressed in two non-technical figures (you might say that the whole book exists to fully support Figs 9-4 & 14-9), whose meanings are elucidated as the reader progresses through the book.

It's in Your DNA

It's in Your DNA
Author: Eugene Rosenberg
Publsiher: Academic Press
Total Pages: 218
Release: 2017-04-11
ISBN 10: 0128125683
ISBN 13: 9780128125687
Language: EN, FR, DE, ES & NL

It's in Your DNA Book Review:

It's in Your DNA: From Discovery to Structure, Function and Role in Evolution, Cancer and Aging describes, in a clear, approachable manner, the progression of the experiments that eventually led to our current understanding of DNA. This fascinating work tells the whole story from the discovery of DNA and its structure, how it replicates, codes for proteins, and our current ability to analyze and manipulate it in genetic engineering to begin to understand the central role of DNA in evolution, cancer, and aging. While telling the scientific story of DNA, this captivating treatise is further enhanced by brief sketches of the colorful lives and personalities of the key scientists and pioneers of DNA research. Major discoveries by Meischer, Darwin, and Mendel and their impacts are discussed, including the merging of the disciplines of genetics, evolutionary biology, and nucleic acid biochemistry, giving rise to molecular genetics. After tracing development of the gene concept, critical experiments are described and a new biological paradigm, the hologenome concept of evolution, is introduced and described. The final two chapters of the work focus on DNA as it relates to cancer and gerontology. This book provides readers with much-needed knowledge to help advance their understanding of the subject and stimulate further research. It will appeal to researchers, students, and others with diverse backgrounds within or beyond the life sciences, including those in biochemistry, genetics/molecular genetics, evolutionary biology, epidemiology, oncology, gerontology, cell biology, microbiology, and anyone interested in these mechanisms in life. Highlights the importance of DNA research to science and medicine Explains in a simple but scientifically correct manner the key experiments and concepts that led to the current knowledge of what DNA is, how it works, and the increasing impact it has on our lives Emphasizes the observations and reasoning behind each novel idea and the critical experiments that were performed to test them

Challenges of Biological Aging

Challenges of Biological Aging
Author: Edward J. Masoro
Publsiher: Springer Publishing Company
Total Pages: 220
Release: 2000-09-05
ISBN 10: 0826100821
ISBN 13: 9780826100825
Language: EN, FR, DE, ES & NL

Challenges of Biological Aging Book Review:

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Handbook of the Biology of Aging

Handbook of the Biology of Aging
Author: Matt Kaeberlein,George Martin
Publsiher: Academic Press
Total Pages: 576
Release: 2015-08-20
ISBN 10: 0124116205
ISBN 13: 9780124116207
Language: EN, FR, DE, ES & NL

Handbook of the Biology of Aging Book Review:

Handbook of the Biology of Aging, Eighth Edition, provides readers with an update on the rapid progress in the research of aging. It is a comprehensive synthesis and review of the latest and most important advances and themes in modern biogerontology, and focuses on the trend of ‘big data’ approaches in the biological sciences, presenting new strategies to analyze, interpret, and understand the enormous amounts of information being generated through DNA sequencing, transcriptomic, proteomic, and the metabolomics methodologies applied to aging related problems. The book includes discussions on longevity pathways and interventions that modulate aging, innovative new tools that facilitate systems-level approaches to aging research, the mTOR pathway and its importance in age-related phenotypes, new strategies to pharmacologically modulate the mTOR pathway to delay aging, the importance of sirtuins and the hypoxic response in aging, and how various pathways interact within the context of aging as a complex genetic trait, amongst others. Covers the key areas in biological gerontology research in one volume, with an 80% update from the previous edition Edited by Matt Kaeberlein and George Martin, highly respected voices and researchers within the biology of aging discipline Assists basic researchers in keeping abreast of research and clinical findings outside their subdiscipline Presents information that will help medical, behavioral, and social gerontologists in understanding what basic scientists and clinicians are discovering New chapters on genetics, evolutionary biology, bone aging, and epigenetic control Provides a close examination of the diverse research being conducted today in the study of the biology of aging, detailing recent breakthroughs and potential new directions

Biology of Aging

Biology of Aging
Author: Roger B. McDonald
Publsiher: Garland Science
Total Pages: 432
Release: 2019-06-07
ISBN 10: 0429641362
ISBN 13: 9780429641367
Language: EN, FR, DE, ES & NL

Biology of Aging Book Review:

Biology of Aging, Second Edition presents the biological principles that have led to a new understanding of the causes of aging and describes how these basic principles help one to understand the human experience of biological aging, longevity, and age-related disease. Intended for undergraduate biology students, it describes how the rate of biological aging is measured; explores the mechanisms underlying cellular aging; discusses the genetic pathways that affect longevity in various organisms; outlines the normal age-related changes and the functional decline that occurs in physiological systems over the lifespan; and considers the implications of modulating the rate of aging and longevity. The book also includes end-of-chapter discussion questions to help students assess their knowledge of the material. Roger McDonald received his Ph.D. from the University of Southern California and is Professor Emeritus in the Department of Nutrition at the University of California, Davis. Dr. McDonald’s research focused on mechanisms of cellular aging and the interaction between nutrition and aging. His research addressed two key topics in the field: the relationship between dietary restriction and lifespan, and the effect of aging on circadian rhythms and hypothalamic regulation. You can contact Dr. McDonald at [email protected] Related Titles Ahmad, S. I., ed. Aging: Exploring a Complex Phenomenon (ISBN 978-1-1381-9697-1) Moody, H. R. & J. Sasser. Gerontology: The Basics (ISBN 978-1-1387-7582-4) Timiras, P. S. Physiological Basis of Aging and Geriatrics (ISBN 978-0-8493-7305-3)

Human Biological Aging

Human Biological Aging
Author: Glenda E. Bilder
Publsiher: John Wiley & Sons
Total Pages: 344
Release: 2016-04-04
ISBN 10: 111896702X
ISBN 13: 9781118967027
Language: EN, FR, DE, ES & NL

Human Biological Aging Book Review:

"Human Biological Aging will introduce the student to human aging from the level of macromolecules to organ systems. Age changes in proteins, DNA, polysaccharides and lipids are discussed relative to known age-related alterations in structure and function produced by free radicals and oxidants. At the cellular level, age-dependent mechanisms that diminish organelle function are described. Cellular phenomena of replicative senescence apoptosis, autophagy and neuroplasticity are detailed as to their contribution to compromised cellular functions. The unique age changes of each organ-system are presented. Some important changes include photo-aging in the integument, increased airway resistance, decreased thoracic chest compliance and reduction of active lung tissue in the pulmonary system, endothelial dysfunction in the cardiovascular system, cognitive changes influenced by negative and positive neuroplasticity in the central nervous system, the impact of presbyopia, presbycusis and sensory fiber loss on sensory perception, sarcopenia and dynapenia in the skeletal muscle system, the effects of menopause, altered stress response and loss of growth hormone in the hypothalamic pituitary system, age changes in bone remodeling and modeling in the skeletal system and prostatic hypertrophy and urinary incontinence in the excretory system. The selection of book material is based on Dr. Bilder's lectures developed over the years as the teacher for a Biology of Aging course at Gwynedd Mercy University. Her lectures covered biological aging from the bottom up - macromolecules to organ-systems. Additionally the student is introduced to methods and measurements in aging and the tools to critique future findings, the effects of classic caloric restriction studies and newer gene manipulations and the evolutionary theory of aging that accepted biological aging as truly biological. Major age-related diseases are absent from this textbook as biogerontologists consider disease distinct from aging. Instead this textbook includes many age changes that highlight how aging is a risk factor for disease. To fully understand biological aging, it is necessary to include primary biological content and then to develop aging insights. For example, to understand the role of aging in the development of sarcopenia and dynapenia, an appreciation of skeletal muscle structure and function is important, after which age changes of sarcopenia and dynapenia and the influence of exercise and protein consumption becomes meaningful. Similarly comprehension of the theories of aging require rudimentary knowledge of oxidation/reduction reactions, protein function, cell organelles, mitosis, acquired immunity, and evolution, to name a few basic biological concepts. Without some biological fundamentals, the student of biological aging struggles to learn the essentials of biological aging and to appreciate the research advances on aging. With regards to format, basic knowledge is given first. Biological terms are defined; key questions to aid with study are given with each chapter. Specifically the reader will learn the current theories of aging, their origins and their value in the scientific literature. The reader will learn why aging is not a disease but a risk for disease. The reader will understand how age changes are measured and appreciate the difficulties of obtaining accurate observations on aging. Thus, in forthcoming findings, the student will be equipped to discriminate between hype and worthwhile advances. This textbook will provide the reader with an overview of the major animal models of aging so that the relevance of this data on conserved mechanisms is evident. Finally, this textbook will give to the reader a framework to incorporate new information. The reader will realize the significance of the health span and gain competency to select lifestyle choices that prolong it."--

The Evolution of Aging

The Evolution of Aging
Author: Theodore C. Goldsmith
Publsiher: Azinet
Total Pages: 189
Release: 2006
ISBN 10: 0978870905
ISBN 13: 9780978870904
Language: EN, FR, DE, ES & NL

The Evolution of Aging Book Review:

Goldsmith provides a historical review of biological aging theories including underlying evolution and genetics issues and describes exciting recent discoveries and new theories that are causing renewed interest in aging-by-design.

Aging and Health - A Systems Biology Perspective

Aging and Health - A Systems Biology Perspective
Author: A.I. Yashin,S.M. Jazwinski
Publsiher: Karger Medical and Scientific Publishers
Total Pages: 206
Release: 2014-10-09
ISBN 10: 3318027308
ISBN 13: 9783318027303
Language: EN, FR, DE, ES & NL

Aging and Health - A Systems Biology Perspective Book Review:

Aging is a major risk factor for chronic diseases, which in turn can provide information about the aging of a biological system. This publication serves as an introduction to systems biology and its application to biological aging. Key pathways and processes that impinge on aging are reviewed, and how they contribute to health and disease during aging is discussed. The evolution of this situation is analyzed, and the consequences for the study of genetic effects on aging are presented. Epigenetic programming of aging, as a continuation of development, creates an interface between the genome and the environment. New research into the gut microbiome describes how this interface may operate in practice with marked consequences for a variety of disorders. This analysis is bolstered by a view of the aging organism as a whole, with conclusions about the mechanisms underlying resilience of the organism to change, and is expanded with a discussion of circadian rhythms in aging. Finally, the book presents an outlook for the development of interventions to delay or to reverse the features of aging. The publication is recommended to students, researchers as well as professionals dealing with public health and public policy related to an aging society.

Handbook of Models for Human Aging

Handbook of Models for Human Aging
Author: P. Michael Conn
Publsiher: Elsevier
Total Pages: 1075
Release: 2011-04-28
ISBN 10: 9780080460062
ISBN 13: 0080460062
Language: EN, FR, DE, ES & NL

Handbook of Models for Human Aging Book Review:

The Handbook of Models for Human Aging is designed as the only comprehensive work available that covers the diversity of aging models currently available. For each animal model, it presents key aspects of biology, nutrition, factors affecting life span, methods of age determination, use in research, and disadvantages/advantes of use. Chapters on comparative models take a broad sweep of age-related diseases, from Alzheimer's to joint disease, cataracts, cancer, and obesity. In addition, there is an historical overview and discussion of model availability, key methods, and ethical issues. Utilizes a multidisciplinary approach Shows tricks and approaches not available in primary publications First volume of its kind to combine both methods of study for human aging and animal models Over 200 illustrations

Handbook of physiology : a critical, comprehensive presentation of physiological knowledge and concepts. Section 11. Aging

Handbook of physiology : a critical, comprehensive presentation of physiological knowledge and concepts. Section 11. Aging
Author: Edward J. Masoro
Publsiher: Anonim
Total Pages: 681
Release: 1995
ISBN 10: 9780195077223
ISBN 13: 0195077229
Language: EN, FR, DE, ES & NL

Handbook of physiology : a critical, comprehensive presentation of physiological knowledge and concepts. Section 11. Aging Book Review:

Discusses organ system & organismic aging/metabolic & molecular aspects of aging/putative interventions/exercise.

Aging

Aging
Author: American Physiological Society (1887- )
Publsiher: Amer Physiological Society
Total Pages: 681
Release: 1995
ISBN 10: 9780195077223
ISBN 13: 0195077229
Language: EN, FR, DE, ES & NL

Aging Book Review:

The aims of this new section of the Handbook of Physiology are two. One is to present a source of basic knowledge about aging including research approaches for use by physiologists as well as other biologists not directly involved in aging research. The other is to provide comprehensive information for gerontologists on the physiological characteristics of aging in mammals, particularly humans. The principles of biological gerontology are presented in Part I, which includes discussions of approaches to the measurement of the rate of aging of populations, the difficulty of assessing aging of the individual, theoretical concepts regarding the nature of aging, and conceptual issues concerning the relationship between aging and disease. Methodological issues unique to aging research are presented in Part II. The focus is on study design and analysis and on cell culture models, animal models and human subject use. Part III provides a detailed description of the cellular and noncellular aspects of aging. This part also discusses the metabolic characteristics of aging. In Part IV, twelve chapters provide comprehensive coverage of the influence of age on the physiology of the nervous systems and the organism. Interventions of aging processes, proposed and established, are the subject of Part V.

Handbook of Physiology: Aging

Handbook of Physiology: Aging
Author: Anonim
Publsiher: Anonim
Total Pages: 329
Release: 1995
ISBN 10:
ISBN 13: STANFORD:36105025353744
Language: EN, FR, DE, ES & NL

Handbook of Physiology: Aging Book Review:

An Introduction to Biological Aging Theory

An Introduction to Biological Aging Theory
Author: Theodore Goldsmith
Publsiher: Azinet
Total Pages: 329
Release: 2011-05-08
ISBN 10: 0978870913
ISBN 13: 9780978870911
Language: EN, FR, DE, ES & NL

An Introduction to Biological Aging Theory Book Review:

Why do we age? The answer to this question is critical to our ability to prevent and treat highly age-related diseases such as cancer and heart disease that now cause the deaths of most people in the developed world. This short book provides an overview of biological aging theories including history, current status, major scientific controversies, and implications for the future of medicine. Major topics include: human mortality as a function of age, aging mechanisms and processes, the programmed vs. non-programmed aging controversy, empirical evidence on aging, and the feasibility of anti-aging and regenerative medicine. Evolution theory is essential to aging theories. Theorists have been struggling for 150 years to explain how aging, deterioration, and consequent death fit with Darwin's survival of the fittest concept. This book explains how continuing genetics discoveries have produced changes in the way we think about evolution that in turn lead to new thinking about the nature of aging.

Ending Aging

Ending Aging
Author: Aubrey de Grey,Michael Rae
Publsiher: St. Martin's Press
Total Pages: 400
Release: 2007-09-04
ISBN 10: 9781429931830
ISBN 13: 1429931833
Language: EN, FR, DE, ES & NL

Ending Aging Book Review:

MUST WE AGE? A long life in a healthy, vigorous, youthful body has always been one of humanity's greatest dreams. Recent progress in genetic manipulations and calorie-restricted diets in laboratory animals hold forth the promise that someday science will enable us to exert total control over our own biological aging. Nearly all scientists who study the biology of aging agree that we will someday be able to substantially slow down the aging process, extending our productive, youthful lives. Dr. Aubrey de Grey is perhaps the most bullish of all such researchers. As has been reported in media outlets ranging from 60 Minutes to The New York Times, Dr. de Grey believes that the key biomedical technology required to eliminate aging-derived debilitation and death entirely—technology that would not only slow but periodically reverse age-related physiological decay, leaving us biologically young into an indefinite future—is now within reach. In Ending Aging, Dr. de Grey and his research assistant Michael Rae describe the details of this biotechnology. They explain that the aging of the human body, just like the aging of man-made machines, results from an accumulation of various types of damage. As with man-made machines, this damage can periodically be repaired, leading to indefinite extension of the machine's fully functional lifetime, just as is routinely done with classic cars. We already know what types of damage accumulate in the human body, and we are moving rapidly toward the comprehensive development of technologies to remove that damage. By demystifying aging and its postponement for the nonspecialist reader, de Grey and Rae systematically dismantle the fatalist presumption that aging will forever defeat the efforts of medical science.

Evolutionary Biology: Concepts and Methods

Evolutionary Biology: Concepts and Methods
Author: Jesse Santos
Publsiher: Anonim
Total Pages: 223
Release: 2019-06-17
ISBN 10: 9781682868393
ISBN 13: 1682868397
Language: EN, FR, DE, ES & NL

Evolutionary Biology: Concepts and Methods Book Review:

Evolutionary biology studies the evolutionary processes of common descent, natural selection and speciation for an understanding of the rich biodiversity of life on Earth. Evolution is a unifying concept in biology. Some of the subfields of evolutionary biology are evolutionary ecology and evolutionary developmental biology. Due to a merge between applied sciences and biological sciences, other fields have emerged such as evolutionary robotics and engineering, economics and architecture. Research in evolutionary biology strives to develop an understanding of less understood natural processes such as the evolution of sexual reproduction, cooperation, ageing and evolvability, etc. Research further encompasses studies of molecular evolution, the genetic architecture of adaptation and the forces of genetic drift, sexual selection and biogeography. This book is compiled in such a manner, that it will provide in-depth knowledge about the concepts and methods of evolutionary biology. It is a valuable compilation of topics, ranging from the basic to the most complex advancements in this field. It aims to equip students and experts with the advanced topics and upcoming concepts in this area.

Life Ascending

Life Ascending
Author: Nick Lane
Publsiher: Profile Books
Total Pages: 469
Release: 2010-10-01
ISBN 10: 1847652220
ISBN 13: 9781847652225
Language: EN, FR, DE, ES & NL

Life Ascending Book Review:

Winner of the 2010 Royal Society Prize for science books Powerful new research methods are providing fresh and vivid insights into the makeup of life. Comparing gene sequences, examining the atomic structure of proteins and looking into the geochemistry of rocks have all helped to explain creation and evolution in more detail than ever before. Nick Lane uses the full extent of this new knowledge to describe the ten greatest inventions of life, based on their historical impact, role in living organisms today and relevance to current controversies. DNA, sex, sight and consciousnesses are just four examples. Lane also explains how these findings have come about, and the extent to which they can be relied upon. The result is a gripping and lucid account of the ingenuity of nature, and a book which is essential reading for anyone who has ever questioned the science behind the glories of everyday life.