Combination Therapy Against Multidrug Resistance

Combination Therapy Against Multidrug Resistance
Author: Mohmmad Younus Wani,Aijaz Ahmad
Publsiher: Academic Press
Total Pages: 268
Release: 2020-04-30
ISBN 10: 0128205784
ISBN 13: 9780128205785
Language: EN, FR, DE, ES & NL

Combination Therapy Against Multidrug Resistance Book Review:

Combination Therapy against Multidrug Resistance explores the potential of combination therapy as an efficient strategy to combat multi-drug resistance. Multidrug resistance (MDR) occurs when microorganisms such as bacteria, fungi, viruses, and parasites are excessively exposed to antimicrobial drugs such as antibiotics, antifungals, or antivirals, and in response the microorganism undergoes mutations or develops different resistance mechanisms to combat the drug for its survival. MDR is becoming an increasingly serious problem in both developed and developing nations. Bacterial resistance to antibiotics has developed faster than the production of new antibiotics, making bacterial infections increasingly difficult to treat, and the same is true for a variety of other diseases. Combination therapy proves to be a promising strategy as it offers potential benefits such as a broad spectrum of efficacy, greater potency than the drugs used in monotherapy, improved safety and tolerability, and reduction in the number of resistant organisms. This book considers how combination therapy can be applied in multiple situations, including cancer, HIV, tuberculosis, fungal infections, and more. Combination Therapy Against Multidrug Resistance gathers the most relevant information on the prospects of combination therapy as a strategy to combat multridrug resistance and helping to motivate the industrial sector and government agencies to invest more in research and development of this strategy as a weapon to tackle the multidrug resistance problem. It will be useful to academics and researchers involved in the development of new antimicrobial or antiinfective agents and treatment strtategies to combat multidrug resistance. Clinicians and medical nurses working in the field of infection prevention and control (IPC) will also find the book relevant Explores strategic methods with investigation of both short- and long-term goals to combat multidrug resistance Presents a broad scope to understand fully the ways to apply combined therapy to multidrug resistance Provides an overview of combination therapy, but also includes specific cases such as cancer, tuberculosis, HIV and malaria

Combating Antimicrobial Resistance A One Health Approach

Combating Antimicrobial Resistance   A One Health Approach
Author: Ghassan M. Matar,Antoine Andremont
Publsiher: Frontiers Media SA
Total Pages: 329
Release: 2020-02-14
ISBN 10: 2889635155
ISBN 13: 9782889635153
Language: EN, FR, DE, ES & NL

Combating Antimicrobial Resistance A One Health Approach Book Review:

Drug Discovery Targeting Drug Resistant Bacteria

Drug Discovery Targeting Drug Resistant Bacteria
Author: Prashant Kesharwani,Sidharth Chopra,Arunava Dasgupta
Publsiher: Academic Press
Total Pages: 432
Release: 2020-05-15
ISBN 10: 0128184817
ISBN 13: 9780128184813
Language: EN, FR, DE, ES & NL

Drug Discovery Targeting Drug Resistant Bacteria Book Review:

Drug Discovery Targeting Drug-Resistant Bacteria explores the status and possible future of developments in fighting drug-resistant bacteria. The book covers the majority of microbial diseases and the drugs targeting them. In addition, it discusses the potential targeting strategies and innovative approaches to address drug resistance. It brings together academic and industrial experts working on discovering and developing drugs targeting drug-resistant (DR) bacterial pathogens. New drugs active against drug-resistant pathogens are discussed, along with new strategies being used to discover molecules acting via new modes of action. In addition, alternative therapies such as peptides and phages are included. Pharmaceutical scientists, microbiologists, medical professionals, pathologists, researchers in the field of drug discovery, infectious diseases and microbial drug discovery both in academia and in industrial settings will find this book helpful. Written by scientists with extensive industrial experience in drug discovery Provides a balanced view of the field, including its challenges and future directions Includes a special chapter on the identification and development of drugs against pathogens which exhibit the potential to be used as weapons of war

Contemporary Topics of Pneumonia

Contemporary Topics of Pneumonia
Author: Zissis Chroneos
Publsiher: BoD – Books on Demand
Total Pages: 222
Release: 2017-12-20
ISBN 10: 9535137077
ISBN 13: 9789535137078
Language: EN, FR, DE, ES & NL

Contemporary Topics of Pneumonia Book Review:

Pneumonia is an inflammatory disease of the air sacs and surrounding interstitium caused by infectious agents or by endogenous inflammatory tissue disorder termed interstitial pneumonia. The present book covers contemporary topics of community, hospital, and health care-related bacterial and viral pneumonia in the setting of drug resistance, environmental exposures, climate change, hormonal influences, and gender. The topic of interstitial pneumonia is brought under the lens of an immune-related connective tissue disease.

Antibiotic Resistance

Antibiotic Resistance
Author: Kateryna Kon,Mahendra Rai
Publsiher: Academic Press
Total Pages: 436
Release: 2016-06-14
ISBN 10: 0128036680
ISBN 13: 9780128036686
Language: EN, FR, DE, ES & NL

Antibiotic Resistance Book Review:

Antibiotic Resistance: Mechanisms and New Antimicrobial Approaches discusses up-to-date knowledge in mechanisms of antibiotic resistance and all recent advances in fighting microbial resistance such as the applications of nanotechnology, plant products, bacteriophages, marine products, algae, insect-derived products, and other alternative methods that can be applied to fight bacterial infections. Understanding fundamental mechanisms of antibiotic resistance is a key step in the discovery of effective methods to cope with resistance. This book also discusses methods used to fight antibiotic-resistant infection based on a deep understanding of the mechanisms involved in the development of the resistance. Discusses methods used to fight antibiotic-resistant infection based on a deep understanding of mechanisms involved in the development of the resistance Provides information on modern methods used to fight antibiotic resistance Covers a wide range of alternative methods to fight bacterial resistance, offering the most complete information available Discusses both newly emerging trends and traditionally applied methods to fight antibiotic resistant infections in light of recent scientific developments Offers the most up-to-date information in fighting antibiotic resistance Includes involvement of contributors all across the world, presenting questions of interest to readers of both developed and developing countries

Fighting Multidrug Resistance with Herbal Extracts Essential Oils and Their Components

Fighting Multidrug Resistance with Herbal Extracts  Essential Oils and Their Components
Author: Mahendra Rai,Kateryna Kon
Publsiher: Academic Press
Total Pages: 296
Release: 2013-05-24
ISBN 10: 0124017088
ISBN 13: 9780124017085
Language: EN, FR, DE, ES & NL

Fighting Multidrug Resistance with Herbal Extracts Essential Oils and Their Components Book Review:

Fighting Multidrug Resistance with Herbal Extracts, Essential Oils and their Components offers scientists a single source aimed at fighting specific multidrug-resistant (MDR) microorganisms such as bacteria, protozoans, viruses and fungi using natural products. This essential reference discusses herbal extracts and essential oils used or under investigation to treat MDR infections, as well as those containing antimicrobial activity that could be of potential interest in future studies against MDR microorganisms. The need to combat multidrug-resistant microorganisms is an urgent one and this book provides important coverage of mechanism of action, the advantages and disadvantages of using herbal extracts, essential oils and their components and more to aid researchers in effective antimicrobial drug discovery Addresses the need to develop safe and effective approaches to coping with resistance to all classes of antimicrobial drugs Provides readers with current evidence-based content aimed at using herbal extracts and essential oils in antimicrobial drug development Includes chapters devoted to the activity of herbal products against herpes, AIDS, tuberculosis, drug-resistant cancer cells and more

Antibiotics and Bacterial Resistance

Antibiotics and Bacterial Resistance
Author: Wiley
Publsiher: John Wiley & Sons
Total Pages: 146
Release: 2013-01-14
ISBN 10: 1118580915
ISBN 13: 9781118580912
Language: EN, FR, DE, ES & NL

Antibiotics and Bacterial Resistance Book Review:

The need for novel antibiotics is greater now than perhaps anytime since the pre-antibiotic era. Indeed, the recent collapse ofmany pharmaceutical antibacterial groups, combined with theemergence of hypervirulent and pan-antibiotic-resistant bacteriahas severely compromised infection treatment options and led todramatic increases in the incidence and severity of bacterialinfections. This collection of reviews and laboratory protocols gives thereader an introduction to the causes of antibiotic resistance, thebacterial strains that pose the largest danger to humans (i.e.,streptococci, pneumococci and enterococci) and the antimicrobialagents used to combat infections with these organisms. Some newavenues that are being investigated for antibiotic development arealso discussed. Such developments include the discovery of agentsthat inhibit bacterial RNA degradation, the bacterial ribosome, andstructure-based approaches to antibiotic drug discovery. Two laboratory protocols are provided to illustrate differentstrategies for discovering new antibiotics. One is a bacterialgrowth inhibition assay to identify inhibitors of bacterial growththat specifically target conditionally essential enzymes in thepathway of interest. The other protocol is used to identifyinhibitors of bacterial cell-to-cell signaling. This e-book — a curated collection from eLS, WIREs, andCurrent Protocols — offers a fantastic introduction to thefield of antibiotics and antibiotic resistance for students orinterdisciplinary collaborators. Table of Contents: Introduction Antibiotics and the Evolution of Antibiotic Resistance eLS Jose L Martinez, Fernando Baquero Antimicrobials Against Streptococci, Pneumococci andEnterococci eLS Susan Donabedian, Adenike Shoyinka Techniques & Applications RNA decay: a novel therapeutic target in bacteria WIREs RNA Tess M. Eidem, Christelle M. Roux, Paul M. Dunman Antibiotics that target protein synthesis WIREs RNA Lisa S. McCoy, Yun Xie, Yitzhak Tor Methods High-Throughput Assessment of Bacterial Growth Inhibition byOptical Density Measurements Current Protocols Chemical Biology Jennifer Campbell Structure-Based Approaches to Antibiotic Drug Discovery Current Protocols Microbiology George Nicola, Ruben Abagyan Novel Approaches to Bacterial Infection Therapy by Interferingwith Cell-to-Cell Signaling Current Protocols Microbiology David A. Rasko, Vanessa Sperandio

Beyond Antimicrobials Non Traditional Approaches to Combating Multidrug Resistant Bacteria

Beyond Antimicrobials  Non Traditional Approaches to Combating Multidrug Resistant Bacteria
Author: Natalia V. Kirienko,Laurence Rahme,You-Hee Cho
Publsiher: Frontiers Media SA
Total Pages: 329
Release: 2019-12-24
ISBN 10: 2889632563
ISBN 13: 9782889632565
Language: EN, FR, DE, ES & NL

Beyond Antimicrobials Non Traditional Approaches to Combating Multidrug Resistant Bacteria Book Review:

Escherichia coli

Escherichia coli
Author: Amidou Samie
Publsiher: BoD – Books on Demand
Total Pages: 434
Release: 2017-07-12
ISBN 10: 9535133292
ISBN 13: 9789535133292
Language: EN, FR, DE, ES & NL

Escherichia coli Book Review:

Escherichia coli is a versatile organism and very diverse. Members of this species vary from very pathogenic agents causing different types of diseases including meningitis, gastroenteritis, and septicemia, just to cite a few, to harmless organisms living in the intestines of both humans and animals. E. coli has also been used as a model organism for most bacteria except a few. For this reason, its study provides a huge advantage and can help understand the mechanisms involved in different processes such as pathogenesis, environmental disinfection, nutrient utilization, antibiotic resistance, and diagnostic/detection methods, and these are indeed the topics discussed in this book. The book has been divided into four main sections representing the different facets of E. coli applications, which include disease, biotechnology, environmental engineering and innovative approaches to detection, and lastly its physiology and cell biology. Such processes can be applied to the study of other organisms as well considering the development of diversity; for example, many organisms are capable of horizontal gene transfer, which is capable of increasing the fitness of the bacterial organisms involved and has a great impact on the control of such bacterial organism.

Infection Control

Infection Control
Author: Silpi Basak
Publsiher: BoD – Books on Demand
Total Pages: 102
Release: 2013-05-29
ISBN 10: 9535111450
ISBN 13: 9789535111450
Language: EN, FR, DE, ES & NL

Infection Control Book Review:

Health Care associated infection (HAI) is an emerging problem worldwide. HAI causes increased morbidity, mortality and average length of stay of the patient in the hospital. HAI also imposes economic burden on the patient, health care set up and also State and National Health care system. It has been estimated that 5 10 % of all hospital admission suffers from HAI even in developed countries. But 30% of HAI are preventable, if we follow the infection control practices properly especially hand hygiene while giving patient care. Hence, in this book importance has been given to Infection Control practices along with emerging trends of HAI due to Pseudomonas aeruginosa, Acinetobacter species etc.

Annals of the Academy of Medicine Singapore

Annals of the Academy of Medicine  Singapore
Author: Academy of Medicine (Singapore)
Publsiher: Unknown
Total Pages: 329
Release: 2008
ISBN 10:
ISBN 13: UCLA:L0099049660
Language: EN, FR, DE, ES & NL

Annals of the Academy of Medicine Singapore Book Review:

Severe Community Acquired Pneumonia

Severe Community Acquired Pneumonia
Author: Jordi Rello,Kenneth V. Leeper
Publsiher: Springer Science & Business Media
Total Pages: 194
Release: 2013-11-11
ISBN 10: 1461516315
ISBN 13: 9781461516316
Language: EN, FR, DE, ES & NL

Severe Community Acquired Pneumonia Book Review:

Severe Community Acquired Pneumonia is a book in which chapters are authored and the same topics discussed by North American and European experts. This approach provides a unique opportunity to view the different perspectives and points of view on this subject. Severe CAP is a common clinical problem encountered in the ICU setting. This book reviews topics concerning the pathogenesis, diagnosis and management of SCAP. The discussions on the role of alcohol in severe CAP and adjunctive therapies are important topics that further our understanding of this severe respiratory infection.

Cancer Drug Resistance

Cancer Drug Resistance
Author: Beverly A. Teicher
Publsiher: Springer Science & Business Media
Total Pages: 617
Release: 2007-11-09
ISBN 10: 1597450359
ISBN 13: 9781597450355
Language: EN, FR, DE, ES & NL

Cancer Drug Resistance Book Review:

Leading experts summarize and synthesize the latest discoveries concerning the changes that occur in tumor cells as they develop resistance to anticancer drugs, and suggest new approaches to preventing and overcoming it. The authors review physiological resistance based upon tumor architecture, cellular resistance based on drug transport, epigenetic changes that neutralize or bypass drug cytotoxicity, and genetic changes that alter drug target molecules by decreasing or eliminating drug binding and efficacy. Highlights include new insights into resistance to antiangiogenic therapies, oncogenes and tumor suppressor genes in therapeutic resistance, cancer stem cells, and the development of more effective therapies. There are also new findings on tumor immune escape mechanisms, gene amplification in drug resistance, the molecular determinants of multidrug resistance, and resistance to taxanes and Herceptin.

Cumulated Index Medicus

Cumulated Index Medicus
Author: Anonim
Publsiher: Unknown
Total Pages: 329
Release: 1999
ISBN 10:
ISBN 13: UIUC:30112042529997
Language: EN, FR, DE, ES & NL

Cumulated Index Medicus Book Review:

Guidelines for the Programmatic Management of Drug resistant Tuberculosis

Guidelines for the Programmatic Management of Drug resistant Tuberculosis
Author: World Health Organization
Publsiher: World Health Organization
Total Pages: 247
Release: 2008
ISBN 10: 9241547588
ISBN 13: 9789241547581
Language: EN, FR, DE, ES & NL

Guidelines for the Programmatic Management of Drug resistant Tuberculosis Book Review:

The emergence of extensively drug-resistant strains of tuberculosis, especially in countries with a high prevalence of human immunodeficiency virus, is a serious threat to global public health and jeopardizes efforts to effectively control the disease. This publication offers updated recommendations for the diagnosis and management of drug-resistant tuberculosis in a variety of geographical, economic and social settings, and the recording of data that enables the monitoring and evaluation of programs.--Publisher's description.

Challenges to Tackling Antimicrobial Resistance Economic and Policy Responses

Challenges to Tackling Antimicrobial Resistance Economic and Policy Responses
Author: OECD,World Health Organization
Publsiher: OECD Publishing
Total Pages: 250
Release: 2020-04-01
ISBN 10: 1108864120
ISBN 13: 9781108864121
Language: EN, FR, DE, ES & NL

Challenges to Tackling Antimicrobial Resistance Economic and Policy Responses Book Review:

Antimicrobial resistance (AMR) is a biological mechanism whereby a microorganism evolves over time to develop the ability to become resistant to antimicrobial therapies such as antibiotics. The drivers of and potential solutions to AMR are complex, often spanning multiple sectors. The internationally recognized response to AMR advocates for a ‘One Health’ approach, which requires policies to be developed and implemented across human, animal, and environmental health.

Antibiotic Basics for Clinicians

Antibiotic Basics for Clinicians
Author: Alan Hauser
Publsiher: Lippincott Williams & Wilkins
Total Pages: 336
Release: 2018-08-14
ISBN 10: 1496385934
ISBN 13: 9781496385932
Language: EN, FR, DE, ES & NL

Antibiotic Basics for Clinicians Book Review:

Publisher's Note: Products purchased from 3rd Party sellers are not guaranteed by the Publisher for quality, authenticity, or access to any online entitlements included with the product. Popular as a classroom text, for review, and as a clinical quick-reference, this time-saving resource helps medical students master the rationale behind antibiotic selection for common bacterial pathogens and infectious diseases. Updated content reflects the latest antibiotic medications available on the market, and new full-color illustrations strengthen users’ understanding of the application of antibiotic drug treatment.

Multi Drug Resistance in Cancer

Multi Drug Resistance in Cancer
Author: Jun Zhou
Publsiher: Humana Press
Total Pages: 492
Release: 2012-08-09
ISBN 10: 9781617796647
ISBN 13: 1617796646
Language: EN, FR, DE, ES & NL

Multi Drug Resistance in Cancer Book Review:

Chemotherapy is one of the major treatment options for cancer patients; however, the efficacy of chemotherapeutic management of cancer is severely limited by multidrug resistance, in that cancer cells become simultaneously resistant to many structurally and mechanistically unrelated drugs. In the past three decades, a number of mechanisms by which cancer cells acquire multidrug resistance have been discovered. In addition, the development of agents or strategies to overcome resistance has been the subject of intense study. This book contains comprehensive and up-to-date reviews of multidrug resistance mechanisms, from over-expression of ATP-binding cassette drug transporters such as P-glycoprotein, multidrug resistance-associated proteins, and breast cancer resistance p- tein to the drug ratio-dependent antagonism and the paradigm of cancer stem cells. The book also includes strategies to overcome multidrug resistance, from the development of compounds that inhibit drug transporter function to the modulation of transporter expression. In addition, this book contains techniques for the detection and imaging of drug transporters, methods for the investigation of drug resistance in animal models, and strategies to evaluate the efficacy of resistance reversal agents. The book intends to provide a state-of-the-art collection of reviews and methods for both basic and clinician investigators who are interested in cancer multidrug resistance mechanisms and reversal strategies. Tianjin, China Jun Zhou v Contents Preface. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . v Contributors. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ix 1 Multidrug Resistance in Cancer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 Bruce C. Baguley 2 Multidrug Resistance in Oncology and Beyond: From Imaging of Drug Efflux Pumps to Cellular Drug Targets . . . . . . . . . . . . . . . . . . . . . . . . . .

Towards Optimal Utilization of Drugs

Towards Optimal Utilization of Drugs
Author: Cyprian O. Onyeji
Publsiher: Unknown
Total Pages: 42
Release: 2007
ISBN 10:
ISBN 13: STANFORD:36105124240685
Language: EN, FR, DE, ES & NL

Towards Optimal Utilization of Drugs Book Review:

Advances in HIV and AIDS Control

Advances in HIV and AIDS Control
Author: Samuel Ikwaras Okware
Publsiher: BoD – Books on Demand
Total Pages: 258
Release: 2018-12-12
ISBN 10: 1789846021
ISBN 13: 9781789846027
Language: EN, FR, DE, ES & NL

Advances in HIV and AIDS Control Book Review:

The HIV epidemic has had a significant and profound impact on the world and health resources. Considerable progress has been made in understanding the risks and drivers of the epidemic. Antiretroviral drugs have relieved human suffering and prolonged life. However, access to quality management needs to scale up and be made universal. This book discusses critical issues related to the treatment of HIV infection and related co-infections and challenges in adherence and discordancy. New vaccine approaches discussed may provide the ultimate solution for eradication. Sharing knowledge from various experts in medical and basic sciences improves the quality of care for this persistent global threat. This book discusses emerging advances in HIV-AIDS management to support strategies for control and elimination.