Colorectal Neoplasia and the Colorectal Microbiome

Colorectal Neoplasia and the Colorectal Microbiome
Author: Martin H. Floch
Publsiher: Academic Press
Total Pages: 270
Release: 2020-08-15
ISBN 10: 0128225610
ISBN 13: 9780128225615
Language: EN, FR, DE, ES & NL

Colorectal Neoplasia and the Colorectal Microbiome Book Review:

Colorectal Neoplasia and the Microbiome: Dysplasia, Probiotics, and Fusobacteria provides foundational knowledge on the gut microbiome and evidence for an association with colorectal neoplasia. It covers the role of microbiota in causing adenomatous polyps and colorectal cancer as well as the modulatory effect of diet and probiotics. Chapters explain a foundational history of microbiology in the colon, the epidemiology of colon polyps and cancer, dysbiosis, the role of immunology and bacteria, and the diet. The book combines medical and scientific aspects to show mechanistic aspects between microbiota and hosts, clearly presenting the association between microbiota, colonic lesions and possible causal links. The book is essential reading for everyone working with human microbiota including basic scientists, physiologists of the intestine, experts in intestinal microbiota, gastroenterologists, oncologists and surgeon. Provides foundational background on the complete history of microbiology in the colon Offers thorough coverage of the connection between fusobacterium nucleatum, diet and bacteria on colon health Presents the connection between immunology and bacteria in the colon

The Gut Microbiome in Health and Disease

The Gut Microbiome in Health and Disease
Author: Dirk Haller
Publsiher: Springer
Total Pages: 356
Release: 2018-07-27
ISBN 10: 3319905457
ISBN 13: 9783319905457
Language: EN, FR, DE, ES & NL

The Gut Microbiome in Health and Disease Book Review:

The book provides an overview on how the gut microbiome contributes to human health. The readers will get profound knowledge on the connection between intestinal microbiota and immune defense systems. The tools of choice to study the ecology of these highly-specialized microorganism communities such as high-throughput sequencing and metagenomic mining will be presented. In addition the most common diseases associated to the composition of the gut flora are discussed in detail. The book will address researchers, clinicians and advanced students working in biomedicine, microbiology and immunology.

Microbiome and Cancer

Microbiome and Cancer
Author: Erle S. Robertson
Publsiher: Springer
Total Pages: 401
Release: 2019-02-20
ISBN 10: 3030041557
ISBN 13: 9783030041557
Language: EN, FR, DE, ES & NL

Microbiome and Cancer Book Review:

This book ventures into a new and exciting area of discovery that directly ties our current knowledge of cancer to the discovery of microorganisms associated with different types of cancers. Recent studies demonstrate that microorganisms are directly linked to the establishment of cancers and that they can also contribute to the initiation, as well as persistence of, the cancers. Microbiome and Cancer covers the current knowledge of microbiome and its association with human cancers. It provides important reading for novices, senior undergraduates in cancer and microbiology, graduate students, junior investigators, residents, fellows and established investigators in the fields of cancer and microbiology. We cover areas related to known, broad concepts in microbiology and how they can relate to the ongoing discoveries of the micro-environment and the changes in the metabolic and physiologic states in that micro-environment, which are important for the ongoing nurturing and survival of the poly-microbial content that dictates activities in that micro-environment. We cover the interactions of microorganisms associated with gastric carcinomas, which are important for driving this particular cancer. Additional areas include oral cancers, skin cancers, ovarian cancers, breast cancers, nasopharyngeal cancers, lung cancers, mesotheliomas, Hodgkin’s and non-Hodgkin’s lymphomas, glioblastoma multiforme, hepatocellular carcinomas, as well as the inflammatory response related to the infectious agents in cancers. This book covers the metabolic changes that occur because of infection and their support for development of cancers, chronic infection and development of therapeutic strategies for detection and control of the infection. The field of microbiome research has exploded over the last five years, and we are now understanding more and more about the context in which microorganisms can contribute to the onset of cancers in humans. The field of microbiome research has demonstrated that the human body has specific biomes for tissues and that changes in these biomes at the specific organ sites can result in disease. These changes can result in dramatic differences in metabolic shifts that, together with genetic mutations, will produce the perfect niche for establishment of the particular infection programmes in that organ site. We are just beginning to understand what those changes are and how they influence the disease state. Overall, we hope to bring together the varying degrees of fluctuations in the microbiome at the major organ sites and how these changes affect the normal cellular processes because of dysregulation, leading to proliferation of the associated tissues.

Intestinal Tumorigenesis

Intestinal Tumorigenesis
Author: Vincent W. Yang,Agnieszka B. Bialkowska
Publsiher: Springer
Total Pages: 445
Release: 2015-09-19
ISBN 10: 3319199862
ISBN 13: 9783319199863
Language: EN, FR, DE, ES & NL

Intestinal Tumorigenesis Book Review:

This volume includes the information necessary to understand recent critical advances in the mechanisms of intestinal tumorigenesis and to comprehend the complexity of the process. The volume aims to entice new researchers to participate in relevant studies, and to provide a forum for discussion within the scientific community to shape future research in this field. Discoveries in intestinal tumorigenesis lead to further understanding of mechanisms involved in colon cancer. Additionally, advancements in techniques and methods open the doors for new approaches to better define the molecular and organismal mechanisms of intestinal tumorigenesis. Chapters are authored by widely published authorities in the field. Each year, there are close to 150,000 new cases of colorectal cancer, which results in approximately 50,000 deaths per year in the United States; these figures render colorectal cancer a significant health concern. Studies attempting to understand the mechanisms of development and progression of colorectal cancer have been ongoing for decades and each year brings new discoveries yielding a better comprehension of the underlying processes at work.

Mechanisms Underlying Host Microbiome Interactions in Pathophysiology of Human Diseases

Mechanisms Underlying Host Microbiome Interactions in Pathophysiology of Human Diseases
Author: Jun Sun,Pradeep K. Dudeja
Publsiher: Springer
Total Pages: 381
Release: 2018-01-26
ISBN 10: 149397534X
ISBN 13: 9781493975341
Language: EN, FR, DE, ES & NL

Mechanisms Underlying Host Microbiome Interactions in Pathophysiology of Human Diseases Book Review:

Only recently have we begun to appreciate the role of microbiome in health and disease. Environmental factors and change of life style including diet significantly shape human microbiome that in turn appears to modify gut barrier function affecting nutrient & electrolyte absorption and inflammation. Approaches that can reverse the gut dysbiosis represent as reasonable and novel strategies for restoring the balance between host and microbes. In the book, we offer summary and discussion on the advances in understanding of pathophysiological mechanisms of microbial host interactions in human diseases. We will not only discuss intestinal bacterial community, but also viruses, fungi and oral microbiome. Microbiome studies will facilitate diagnosis, functional studies, drug development and personalized medicine. Thus, this book will further highlight the microbiome in the context of health and disease, focusing on mechanistic concepts that underlie the complex relationships between host and microbes.

Probiotics and Bioactive Carbohydrates in Colon Cancer Management

Probiotics and Bioactive Carbohydrates in Colon Cancer Management
Author: Maya Raman,Padma Ambalam,Mukesh Doble
Publsiher: Springer
Total Pages: 124
Release: 2015-10-27
ISBN 10: 8132225864
ISBN 13: 9788132225867
Language: EN, FR, DE, ES & NL

Probiotics and Bioactive Carbohydrates in Colon Cancer Management Book Review:

This book describes the dietary habits (such as use of probiotics, synbiotics, prebiotics and dietary fiber) that could modify and reduce the risk of developing colorectal cancer (CRC). The book will be of practical and scientific use to academicians, research scholars, students, health professionals, nutritionists, etc. and could support the cause of preventing CRC by adopting smarter food habits. CRC is the third leading cause of death, in terms of both incidence and mortality, among men and women. Excess consumption of red and processed meat, roasted coffee, etc. have shown an increase in CRC, indicating that compounds formed in food containing free amino acids and sugars interact at elevated temperatures to form mutagens or carcinogens. Standard treatment options for CRC include invasive surgery and chemotherapy or radiation. Several lifestyle and dietary factors could prevent this ailment. Probiotics, prebiotics and synbiotics that are found in functional foods, health supplements and nutraceuticals and short chain fatty acids that are formed in the colon as a result of microbial fermentation of undigested bioactive carbohydrates by Bifidobacterium and Lactobacillus inhibit colonic epithelial cells and minimize inflammation, thereby exhibiting immunomodulatory effects. This book tries to address the novel unexplored benefits and mechanism of action of these functional foods.

Cancer Epigenetics for Precision Medicine

Cancer Epigenetics for Precision Medicine
Author: Ramona G. Dumitrescu,Mukesh Verma
Publsiher: Humana
Total Pages: 298
Release: 2019-09-17
ISBN 10: 9781493993833
ISBN 13: 1493993836
Language: EN, FR, DE, ES & NL

Cancer Epigenetics for Precision Medicine Book Review:

This volume discusses certain epigenetic changes recognized in early carcinogenic lesions and different tumors, as well as factors that alter the epigenome and epigenetic profile such as diet, alcohol, immunity, circadian rhythm, and more. The chapters in this book further delve into this field and cover topics such as epigenome-based precision medicine in lung cancer; interplay between genetic and epigenetic changes in breast cancer subtypes; genetic regulation of PDCD1 gene in cancer immunology; and pyrosequencing methylation analysis. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and authoritative, Cancer Epigenetics for Precision Medicine: Methods and Protocols is a valuable resource to help researchers and scientists identify these specific biomarkers and work towards the prevention, diagnosis, and prognosis of different cancers in the future.

Colitis Associated Cancer

Colitis Associated Cancer
Author: Masato Kusunoki
Publsiher: Springer
Total Pages: 150
Release: 2015-10-01
ISBN 10: 4431555226
ISBN 13: 9784431555223
Language: EN, FR, DE, ES & NL

Colitis Associated Cancer Book Review:

As the number of patients with colitis-associated cancer (CAC) is on the increase, the purpose of this book is to review the latest topics concerning management of the disease. In recent years, the diagnostic power of endoscopy and molecular pathology has also grown tremendously, as a result of which they now have a far greater influence on the treatment of CAC. At the moment, appropriate monitoring programs for ulcerative colitis and Crohn’s disease remain uncertain. At the same time, the latest findings on DNA methylation and microRNAs hold the promise of making revolutionary changes in these areas. Moreover, recent drug advances in the treatment of inflammatory bowel diseases have changed surgical indications. On the other hand, the indication of mucosectomy on colorectal cancer in ulcerative colitis and prophylactic abdominoperineal resection for Crohn’s disease remain controversial. This book provides the latest information on the remaining issues of CAC from the point of view of expert surgeons.

The Gut Microbiome

The Gut Microbiome
Author: Gyula Mozsik
Publsiher: BoD – Books on Demand
Total Pages: 112
Release: 2016-11-02
ISBN 10: 9535127500
ISBN 13: 9789535127505
Language: EN, FR, DE, ES & NL

The Gut Microbiome Book Review:

In the last decades, the importance of gut microbiome has been linked to medical research on different diseases. Developments of other medical disciplines (human clinical pharmacology, clinical nutrition and dietetics, everyday medical treatments of antibiotics, changes in nutritional inhabits in different countries) also called attention to study the changes in the gut microbiome. This book contains five excellent review chapters in the field of gut microbiome, written by researchers from the USA, Canada, China, and India. These chapters present a critical review about some clinically important changes in the gut microbiome in the development of some human diseases and therapeutic possibilities (liver disease, cardiovascular diseases, brain diseases, gastrointestinal diseases). The book brings to attention the essential role of gut microbiome in keeping our life healthy. This book is addressed to experts of microbiology, podiatrists, gastroenterologists, internists, nutritional experts, cardiologists, basic and clinical researchers, as well as experts in the field of food industry.

METABIOTICS

METABIOTICS
Author: Boris A. Shenderov,Alexander V. Sinitsa,Mikhail M. Zakharchenko,Christine Lang
Publsiher: Springer Nature
Total Pages: 123
Release: 2020-02-13
ISBN 10: 3030341674
ISBN 13: 9783030341671
Language: EN, FR, DE, ES & NL

METABIOTICS Book Review:

Aimed at students, researchers, nutritionists, and developers in food technology, this research text addresses the nascent field of metabiotics. Metabiotics are products based on components of cells, metabolites, and signaling molecules released by probiotic strains, engineered to optimize host-specific physiological functions in a way that traditional probiotics cannot. This book examines the history, processes, design, classifications, and functions of metabiotics. It includes an overview of the composition and function of the gut microbiota, and discusses development of target-specific metabiotics. Further coverage includes comparisons to traditional probiotics, as well as probiotic safety and side-effects. Metabiotics: Present State, Challenges and Perspectives provides a complete history and understanding of this new field, the next phase of the probiotic industry.

Diet Microbiome and Health

Diet  Microbiome and Health
Author: Alexandru Mihai Grumezescu,Alina-Maria Holban
Publsiher: Academic Press
Total Pages: 526
Release: 2018-01-02
ISBN 10: 0128114924
ISBN 13: 9780128114926
Language: EN, FR, DE, ES & NL

Diet Microbiome and Health Book Review:

Diet, Microbiome and Health, Volume 11, in the Handbook of Food Bioengineering series, presents the most up-to-date research to help scientists, researchers and students in the field of food engineering understand the different microbial species we have in our guts, why they are important to human development, immunity and health, and how to use that understanding to further promote research to create healthy food products. In addition, the book provides studies that clearly demonstrate how dietary preferences and social behavior significantly impact the diversity of microbial species in the gut and their numeric values, which may balance health and disease. Highlights research discoveries on how gut microbiota influence and are impacted by health and disease Includes information on and examples of healthy foods Discusses gut microbiota in autism, GI disease, neuropsychiatric disorders, obesity and metabolic disease Explores the barrier function of the gut Examines how food preferences impact gut microbiota

Clinical Cancer Prevention

Clinical Cancer Prevention
Author: Hans-Jörg Senn,Florian Otto
Publsiher: Springer Science & Business Media
Total Pages: 162
Release: 2011-01-21
ISBN 10: 9783642108587
ISBN 13: 364210858X
Language: EN, FR, DE, ES & NL

Clinical Cancer Prevention Book Review:

This book is based on presentations by some of the world’s leading experts at the Sixth International Conference on Clinical Cancer Prevention, held in St. Gallen, Switzerland, during March 2010. The main themes are the latest advances in the prevention of breast and prostate cancer and the role of infection in the development of liver and gastric cancer. Special emphasis is given to perspectives on the chemoprevention of breast cancer, as the conference included an international consensus meeting on this subject. New research findings are presented and potentially more effective cancer prevention strategies are discussed, with careful consideration of controversies. The expertise of the contributors encompasses genetics and microbiology, epidemiology, and health economics, as well as clinical cancer prevention. This book will be of interest to all who wish to learn about the most recent progress in combating the development of cancer.

The Human Microbiota and Chronic Disease

The Human Microbiota and Chronic Disease
Author: Luigi Nibali,Brian Henderson
Publsiher: John Wiley & Sons
Total Pages: 544
Release: 2016-09-26
ISBN 10: 1118982878
ISBN 13: 9781118982877
Language: EN, FR, DE, ES & NL

The Human Microbiota and Chronic Disease Book Review:

Microbiota-associated pathology can be a direct result of changes in general bacterial composition, such as might be found in periodontitis and bacterial vaginosis, and/or as the result of colonization and/or overgrowth of so called keystone species. The disruption in the composition of the normal human microbiota, or dysbiosis, plays an integral role in human health and human disease. The Human Microbiota and Human Chronic Disease: Dysbioses as a Cause of Human Pathology discusses the role of the microbiota in maintaining human health. The text introduces the reader to the biology of microbial dysbiosis and its potential role in both bacterial disease and in idiopathic chronic disease states. Divided into five sections, the text delineates the concept of the human bacterial microbiota with particular attention being paid to the microbiotae of the gut, oral cavity and skin. A key methodology for exploring the microbiota, metagenomics, is also described. The book then shows the reader the cellular, molecular and genetic complexities of the bacterial microbiota, its myriad connections with the host and how these can maintain tissue homeostasis. Chapters then consider the role of dysbioses in human disease states, dealing with two of the commonest bacterial diseases of humanity – periodontitis and bacterial vaginosis. The composition of some, if not all microbiotas can be controlled by the diet and this is also dealt with in this section. The discussion moves on to the major ‘idiopathic’ diseases afflicting humans, and the potential role that dysbiosis could play in their induction and chronicity. The book then concludes with the therapeutic potential of manipulating the microbiota, introducing the concepts of probiotics, prebiotics and the administration of healthy human faeces (faecal microbiota transplantation), and then hypothesizes as to the future of medical treatment viewed from a microbiota-centric position. Provides an introduction to dysbiosis, or a disruption in the composition of the normal human microbiota Explains how microbiota-associated pathology and other chronic diseases can result from changes in general bacterial composition Explores the relationship humans have with their microbiota, and its significance in human health and disease Covers host genetic variants and their role in the composition of human microbial biofilms, integral to the relationship between human health and human disease Authored and edited by leaders in the field, The Human Microbiota and Human Chronic Disease will be an invaluable resource for clinicians, pathologists, immunologists, cell and molecular biologists, biochemists, and system biologists studying cellular and molecular bases of human diseases.

The Microbiota in Gastrointestinal Pathophysiology

The Microbiota in Gastrointestinal Pathophysiology
Author: Martin H. Floch,Yehuda Ringel,W. Allen Walker
Publsiher: Academic Press
Total Pages: 442
Release: 2016-11-16
ISBN 10: 0128040629
ISBN 13: 9780128040621
Language: EN, FR, DE, ES & NL

The Microbiota in Gastrointestinal Pathophysiology Book Review:

The Microbiota in Gastrointestinal Pathophysiology: Implications for Human Health, Prebiotics, Probiotics and Dysbiosis is a one-stop reference on the state-of-the-art research on gut microbial ecology in relation to human disease. This important resource starts with an overview of the normal microbiota of the gastrointestinal tract, including the esophagus, stomach, Ileum, and colon. The book then identifies what a healthy vs. unhealthy microbial community looks like, including methods of identification. Also included is insight into which features and contributions the microbiota make that are essential and useful to host physiology, as is information on how to promote appropriate mutualisms and prevent undesirable dysbioses. Through the power of synthesizing what is known by experienced researchers in the field, current gaps are closed, raising understanding of the role of the microbiome and allowing for further research. Explains how to modify the gut microbiota and how the current strategies used to do this produce their effects Explores the gut microbiota as a therapeutic target Provides the synthesis of existing data from both mainstream and non-mainstream sources through experienced researchers in the field Serves as a ‘one-stop’ shop for a topic that’s currently spread across a number of various journals

Anti cancer Drugs

Anti cancer Drugs
Author: Jasna Bankovic
Publsiher: BoD – Books on Demand
Total Pages: 196
Release: 2016-12-07
ISBN 10: 9535128132
ISBN 13: 9789535128137
Language: EN, FR, DE, ES & NL

Anti cancer Drugs Book Review:

We are in constant search for new therapeutic options to cure cancer. In this book, you can find out how scientists throughout the world deal with this problem. Readers will learn how to engage nature, chemical synthesis, and cell machinery to design new anticancer agents. Nature has already been very generous in providing us different compounds which are in widespread application. Starting from these resources, various synthetic processes are applied to create synthetic drugs which can be then obtained in large quantities. Also, the cell by itself provides different possibilities to meet the constantly increasing requirements for successful therapy. Explore the book and find out what are the new ways to fight cancer.

Microbiome Insults on the Way to Colorectal Cancer

Microbiome Insults on the Way to Colorectal Cancer
Author: Jackline Joy Martin Lasola
Publsiher: Unknown
Total Pages: 118
Release: 2013
ISBN 10:
ISBN 13: OCLC:861617069
Language: EN, FR, DE, ES & NL

Microbiome Insults on the Way to Colorectal Cancer Book Review:

Gut Microbiome Related Diseases and Therapies

Gut Microbiome Related Diseases and Therapies
Author: Maria Gazouli,George Theodoropoulos
Publsiher: Springer Nature
Total Pages: 326
Release: 2021-04-24
ISBN 10: 3030596427
ISBN 13: 9783030596422
Language: EN, FR, DE, ES & NL

Gut Microbiome Related Diseases and Therapies Book Review:

This book reviews recent knowledge of the role of gut microbiome in health and disease. It covers extensive topics for several diseases, including metabolic-related diseases, allergies, gastrointestinal diseases, psychiatric diseases, and cancer, while also discussing therapeutic approaches by microbiota modification. Comprehensive and cutting-edge, Gut Microbiome-Related Diseases and Therapies deepens a reader’s theoretical expertise in gut microbiome. Graduate and postdoctoral students, medical doctors, and biomedical researchers will benefit from this book.

Theranostics Approaches to Gastric and Colon Cancer

Theranostics Approaches to Gastric and Colon Cancer
Author: Ganji Seeta Rama Raju,L.V.K.S. Bhaskar
Publsiher: Springer Nature
Total Pages: 250
Release: 2020-03-04
ISBN 10: 9811520178
ISBN 13: 9789811520174
Language: EN, FR, DE, ES & NL

Theranostics Approaches to Gastric and Colon Cancer Book Review:

This book highlights the importance of understanding gastric and colon cancer metabolism in guiding diagnosis and drug discovery. It summarizes the correlation between adiponectin and matrix metalloproteinase with colorectal cancer. The book also evaluates the divergent role of hypoxia-inducible factor 1 in colorectal cancer growth and metastasis. After discussing the role of genetic polymorphisms in alcohol metabolizing enzymes and EPHX1 with the onset of colorectal cancer, it reviews the molecular mechanisms of chemoresistance in gastric cancer and novel therapeutic strategies to reverse the chemoresistance of tumors. In addition, the book explores the theranostic role of nanoparticles and therapeutic potential of phytochemicals with regard to colorectal cancer. Given its scope, the book offers a valuable guide for oncologists, academic researchers, pharmaceuticals practitioners, and students who are involved in research and treatment of cancer.

Colorectal Cancer

Colorectal Cancer
Author: Jean-François Beaulieu
Publsiher: Humana
Total Pages: 353
Release: 2019-04-11
ISBN 10: 9781493992782
ISBN 13: 1493992783
Language: EN, FR, DE, ES & NL

Colorectal Cancer Book Review:

This volume explores the latest developments in the study of the mechanisms, diagnostics, screening methods, and therapeutics of colorectal cancer. The book’s chapters are divided into three parts: the chapters in Part One examine techniques used to study the molecular mechanisms in colorectal cancer development and progression. Part Two focuses on the innovative tools used to diagnose and detect cancer lesions in the early stages of cancer. Finally, Part Three discusses recent advancements in treating colorectal tumors and identifying new therapeutic molecules for treatment. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and comprehensive, Colorectal Cancer: Methods and Protocols is a valuable resource for any scientist and researcher interested in this field of study.

Colorectal Cancer

Colorectal Cancer
Author: Jindong Chen
Publsiher: BoD – Books on Demand
Total Pages: 128
Release: 2018-05-16
ISBN 10: 1789231000
ISBN 13: 9781789231007
Language: EN, FR, DE, ES & NL

Colorectal Cancer Book Review:

With international experts sharing their experience and knowledge on these different aspects in the management of colorectal cancer, this book has this opportunity to offer all physicians treating colorectal cancer, as well as researchers, updated information concerning the biology, diagnosis, screening, and treatment of colorectal carcinoma. This book provides a detailed evaluation of diagnostic modalities, in-depth analysis of screening for colorectal cancer, recent advances in treatment, and principles and trends in the management of colorectal cancer. This updated knowledge will be an interesting and informative read for any clinician involved in the management of patients with colorectal cancer. In addition, readers such as related physicians, researchers, and colorectal cancer patients are potential beneficiaries of this book.