Colorectal Neoplasia and the Colorectal Microbiome

Colorectal Neoplasia and the Colorectal Microbiome
Author: Martin H. Floch
Publsiher: Academic Press
Total Pages: 270
Release: 2020-08-15
ISBN 10: 0128225610
ISBN 13: 9780128225615
Language: EN, FR, DE, ES & NL

Colorectal Neoplasia and the Colorectal Microbiome Book Review:

Colorectal Neoplasia and the Microbiome: Dysplasia, Probiotics, and Fusobacteria provides foundational knowledge on the gut microbiome and evidence for an association with colorectal neoplasia. It covers the role of microbiota in causing adenomatous polyps and colorectal cancer as well as the modulatory effect of diet and probiotics. Chapters explain a foundational history of microbiology in the colon, the epidemiology of colon polyps and cancer, dysbiosis, the role of immunology and bacteria, and the diet. The book combines medical and scientific aspects to show mechanistic aspects between microbiota and hosts, clearly presenting the association between microbiota, colonic lesions and possible causal links. The book is essential reading for everyone working with human microbiota including basic scientists, physiologists of the intestine, experts in intestinal microbiota, gastroenterologists, oncologists and surgeon. Provides foundational background on the complete history of microbiology in the colon Offers thorough coverage of the connection between fusobacterium nucleatum, diet and bacteria on colon health Presents the connection between immunology and bacteria in the colon

The Gut Microbiome in Health and Disease

The Gut Microbiome in Health and Disease
Author: Dirk Haller
Publsiher: Springer
Total Pages: 356
Release: 2018-07-27
ISBN 10: 3319905457
ISBN 13: 9783319905457
Language: EN, FR, DE, ES & NL

The Gut Microbiome in Health and Disease Book Review:

The book provides an overview on how the gut microbiome contributes to human health. The readers will get profound knowledge on the connection between intestinal microbiota and immune defense systems. The tools of choice to study the ecology of these highly-specialized microorganism communities such as high-throughput sequencing and metagenomic mining will be presented. In addition the most common diseases associated to the composition of the gut flora are discussed in detail. The book will address researchers, clinicians and advanced students working in biomedicine, microbiology and immunology.

Mechanisms Underlying Host Microbiome Interactions in Pathophysiology of Human Diseases

Mechanisms Underlying Host Microbiome Interactions in Pathophysiology of Human Diseases
Author: Jun Sun,Pradeep K. Dudeja
Publsiher: Springer
Total Pages: 381
Release: 2018-01-26
ISBN 10: 149397534X
ISBN 13: 9781493975341
Language: EN, FR, DE, ES & NL

Mechanisms Underlying Host Microbiome Interactions in Pathophysiology of Human Diseases Book Review:

Only recently have we begun to appreciate the role of microbiome in health and disease. Environmental factors and change of life style including diet significantly shape human microbiome that in turn appears to modify gut barrier function affecting nutrient & electrolyte absorption and inflammation. Approaches that can reverse the gut dysbiosis represent as reasonable and novel strategies for restoring the balance between host and microbes. In the book, we offer summary and discussion on the advances in understanding of pathophysiological mechanisms of microbial host interactions in human diseases. We will not only discuss intestinal bacterial community, but also viruses, fungi and oral microbiome. Microbiome studies will facilitate diagnosis, functional studies, drug development and personalized medicine. Thus, this book will further highlight the microbiome in the context of health and disease, focusing on mechanistic concepts that underlie the complex relationships between host and microbes.

Microbiome and Cancer

Microbiome and Cancer
Author: Erle S. Robertson
Publsiher: Springer
Total Pages: 401
Release: 2019-02-20
ISBN 10: 3030041557
ISBN 13: 9783030041557
Language: EN, FR, DE, ES & NL

Microbiome and Cancer Book Review:

This book ventures into a new and exciting area of discovery that directly ties our current knowledge of cancer to the discovery of microorganisms associated with different types of cancers. Recent studies demonstrate that microorganisms are directly linked to the establishment of cancers and that they can also contribute to the initiation, as well as persistence of, the cancers. Microbiome and Cancer covers the current knowledge of microbiome and its association with human cancers. It provides important reading for novices, senior undergraduates in cancer and microbiology, graduate students, junior investigators, residents, fellows and established investigators in the fields of cancer and microbiology. We cover areas related to known, broad concepts in microbiology and how they can relate to the ongoing discoveries of the micro-environment and the changes in the metabolic and physiologic states in that micro-environment, which are important for the ongoing nurturing and survival of the poly-microbial content that dictates activities in that micro-environment. We cover the interactions of microorganisms associated with gastric carcinomas, which are important for driving this particular cancer. Additional areas include oral cancers, skin cancers, ovarian cancers, breast cancers, nasopharyngeal cancers, lung cancers, mesotheliomas, Hodgkin’s and non-Hodgkin’s lymphomas, glioblastoma multiforme, hepatocellular carcinomas, as well as the inflammatory response related to the infectious agents in cancers. This book covers the metabolic changes that occur because of infection and their support for development of cancers, chronic infection and development of therapeutic strategies for detection and control of the infection. The field of microbiome research has exploded over the last five years, and we are now understanding more and more about the context in which microorganisms can contribute to the onset of cancers in humans. The field of microbiome research has demonstrated that the human body has specific biomes for tissues and that changes in these biomes at the specific organ sites can result in disease. These changes can result in dramatic differences in metabolic shifts that, together with genetic mutations, will produce the perfect niche for establishment of the particular infection programmes in that organ site. We are just beginning to understand what those changes are and how they influence the disease state. Overall, we hope to bring together the varying degrees of fluctuations in the microbiome at the major organ sites and how these changes affect the normal cellular processes because of dysregulation, leading to proliferation of the associated tissues.

Colorectal Cancer Screening

Colorectal Cancer Screening
Author: Joseph Anderson, MD,Charles Kahi, MD
Publsiher: Springer Science & Business Media
Total Pages: 205
Release: 2011-04-23
ISBN 10: 9781607613985
ISBN 13: 1607613980
Language: EN, FR, DE, ES & NL

Colorectal Cancer Screening Book Review:

Colorectal Cancer Screening provides a complete overview of colorectal cancer screening, from epidemiology and molecular abnormalities, to the latest screening techniques such as stool DNA and FIT, Computerized Tomography (CT) Colonography, High Definition Colonoscopes and Narrow Band Imaging. As the text is devoted entirely to CRC screening, it features many facts, principles, guidelines and figures related to screening in an easy access format. This volume provides a complete guide to colorectal cancer screening which will be informative to the subspecialist as well as the primary care practitioner. It represents the only text that provides this up to date information about a subject that is continually changing. For the primary practitioner, information on the guidelines for screening as well as increasing patient participation is presentedd. For the subspecialist, information regarding the latest imaging techniques as well as flat adenomas and chromoendoscopy are covered. The section on the molecular changes in CRC will appeal to both groups. The text includes up to date information about colorectal screening that encompasses the entire spectrum of the topic and features photographs of polyps as well as diagrams of the morphology of polyps as well as photographs of CT colonography images. Algorithms are presented for all the suggested guidelines. Chapters are devoted to patient participation in screening and risk factors as well as new imaging technology. This useful volume explains the rationale behind screening for CRC. In addition, it covers the different screening options as well as the performance characteristics, when available in the literature, for each test. This volume will be used by the sub specialists who perform screening tests as well as primary care practitioners who refer patients to be screened for colorectal cancer.

The Gut Microbiome and Its Relationship to Colorectal Cancer

The Gut Microbiome and Its Relationship to Colorectal Cancer
Author: Elizabeth Shultes
Publsiher: Unknown
Total Pages: 34
Release: 2018
ISBN 10: 1928374650XXX
ISBN 13: OCLC:1126284592
Language: EN, FR, DE, ES & NL

The Gut Microbiome and Its Relationship to Colorectal Cancer Book Review:

Humans are "supraorganisms" composed of human and microbial components. The microbial community, living in and on humans, along with their genome, is called the microbiome. The microbiome is essential to human health because it can play a role in the development of many diseases, including cancer. The gut microbiome contains the highest density of bacteria in the body. Changes in the composition of the gut microbiome are related to colorectal cancer, specifically through the production of metabolites that affect transcription of cancer suppressor genes. `Manipulation of the microbiome through diet and probiotics may lead to new cancer therapies.

Cancer Theranostics

Cancer Theranostics
Author: Xiaoyuan Chen,Stephen Wong
Publsiher: Academic Press
Total Pages: 544
Release: 2014-03-20
ISBN 10: 0124078842
ISBN 13: 9780124078840
Language: EN, FR, DE, ES & NL

Cancer Theranostics Book Review:

Aiding researchers seeking to eliminate multi-step procedures, reduce delays in treatment and ease patient care, Cancer Theranostics reviews, assesses, and makes pertinent clinical recommendations on the integration of comprehensive in vitro diagnostics, in vivo molecular imaging, and individualized treatments towards the personalization of cancer treatment. Cancer Theranostics describes the identification of novel biomarkers to advance molecular diagnostics of cancer. The book encompasses new molecular imaging probes and techniques for early detection of cancer, and describes molecular imaging-guided cancer therapy. Discussion also includes nanoplatforms incorporating both cancer imaging and therapeutic components, as well as clinical translation and future perspectives. Supports elimination of multi-step approaches and reduces delays in treatments through combinatorial diagnosis and therapy Fully assesses cancer theranostics across the emergent field, with discussion of biomarkers, molecular imaging, imaging guided therapy, nanotechnology, and personalized medicine Content bridges laboratory, clinic, and biotechnology industries to advance biomedical science and improve patient management

Novel Approaches to Colorectal Cancer

Novel Approaches to Colorectal Cancer
Author: Anonim
Publsiher: Academic Press
Total Pages: 484
Release: 2021-06-18
ISBN 10: 0128240792
ISBN 13: 9780128240793
Language: EN, FR, DE, ES & NL

Novel Approaches to Colorectal Cancer Book Review:

Novel Approaches to Colorectal Cancer, Volume 151 in the Advances in Cancer Research series, is composed of 11 reviews covering state-of-the-art research relating to the etiology, diagnosis, prevention and treatment of colorectal cancer. The book's chapters were written by recognized experts in the field, and include sections on molecular biomarkers in diagnosis and therapy, the interplay of diet, lifestyle, and the microbiome, early-age onset disease, mutational signature analysis, challenges in early detection, immunotherapy, organoid technology, the role of epigenetic alterations, disparities in minority populations, field carcinogenesis, and cancer as an evolutionary process. Each of these topics provides novel insights and concepts on various aspects of the nature of colorectal cancer, offering new opportunities for the management of a major source of cancer incidence and mortality. Provides information on the timely nature of the included topics, which represent the most current concepts and approaches in cancer research Offers outstanding and original reviews on colorectal cancer research Provides the authority and expertise of the authors, all of whom are highly recognized and conducting state-of-the-art investigations in cancer, with this release focusing on colorectal cancer

Illuminating Colorectal Cancer Genomics by Next Generation Sequencing

Illuminating Colorectal Cancer Genomics by Next Generation Sequencing
Author: Khalid El Bairi
Publsiher: Springer Nature
Total Pages: 185
Release: 2020-09-28
ISBN 10: 3030538214
ISBN 13: 9783030538217
Language: EN, FR, DE, ES & NL

Illuminating Colorectal Cancer Genomics by Next Generation Sequencing Book Review:

This book reviews the potential of next-generation sequencing (NGS) in research on and management of colorectal cancer (CRC), a leading cause of death worldwide and one of the most biologically and clinically heterogeneous cancers. It critically discusses findings from recent large-scale studies, clinical trials and meta-analyses and offers an introduction to the management of CRC in the era of precision medicine. In CRC, dozens of driver and passenger mutations are associated with the malignant transformation of epithelial cells. Consequently, the book discusses recent advances in our understanding of the genetics of CRC as a biomarker, the advent of NGS technologies in modern genomics, and the impact of NGS technology on the management of CRC. Furthermore, it highlights the potential of NGS in the context of liquid biopsy and single-cell sequencing in CRC, as well as its role in shedding light on the link between gut microbiota, immune-checkpoint blockade and CRC. The book concludes with a chapter on the limitations and cost-effectiveness of NGS in CRC. Given its scope, the book will appeal to all those interested in learning about the potential of NGS in advancing CRC research and patient care.

Netter s Gastroenterology

Netter s Gastroenterology
Author: Martin H. Floch
Publsiher: ICON
Total Pages: 900
Release: 2005
ISBN 10: 9781929007134
ISBN 13: 1929007132
Language: EN, FR, DE, ES & NL

Netter s Gastroenterology Book Review:

This comprehensive volume covers major gastrointestinal diseases and conditions, presenting key information on etiology, clinical presentation, differential diagnosis, management and therapy using a consistent, quick-reference format and 300 classic Netter illustrations. Other top medical illustrators have contributed new illustrations--working in the Netter style--and have updated others where appropriate.

Intestinal Tumorigenesis

Intestinal Tumorigenesis
Author: Vincent W. Yang,Agnieszka B. Bialkowska
Publsiher: Springer
Total Pages: 445
Release: 2015-09-19
ISBN 10: 3319199862
ISBN 13: 9783319199863
Language: EN, FR, DE, ES & NL

Intestinal Tumorigenesis Book Review:

This volume includes the information necessary to understand recent critical advances in the mechanisms of intestinal tumorigenesis and to comprehend the complexity of the process. The volume aims to entice new researchers to participate in relevant studies, and to provide a forum for discussion within the scientific community to shape future research in this field. Discoveries in intestinal tumorigenesis lead to further understanding of mechanisms involved in colon cancer. Additionally, advancements in techniques and methods open the doors for new approaches to better define the molecular and organismal mechanisms of intestinal tumorigenesis. Chapters are authored by widely published authorities in the field. Each year, there are close to 150,000 new cases of colorectal cancer, which results in approximately 50,000 deaths per year in the United States; these figures render colorectal cancer a significant health concern. Studies attempting to understand the mechanisms of development and progression of colorectal cancer have been ongoing for decades and each year brings new discoveries yielding a better comprehension of the underlying processes at work.

Multidisciplinary Approach for Colorectal Cancer

Multidisciplinary Approach for Colorectal Cancer
Author: Anonim
Publsiher: Unknown
Total Pages: 135
Release: 2019
ISBN 10: 9781789844009
ISBN 13: 1789844002
Language: EN, FR, DE, ES & NL

Multidisciplinary Approach for Colorectal Cancer Book Review:

Study of Gut Microbiome and Metabolomics Profiling in Colorectal Cancer Patients

Study of Gut Microbiome and Metabolomics Profiling in Colorectal Cancer Patients
Author: Lucky Poh Wah Goh
Publsiher: Unknown
Total Pages: 135
Release: 2019
ISBN 10: 1928374650XXX
ISBN 13: OCLC:1256756373
Language: EN, FR, DE, ES & NL

Study of Gut Microbiome and Metabolomics Profiling in Colorectal Cancer Patients Book Review:

The Human Microbiota and Chronic Disease

The Human Microbiota and Chronic Disease
Author: Luigi Nibali,Brian Henderson
Publsiher: John Wiley & Sons
Total Pages: 544
Release: 2016-09-26
ISBN 10: 1118982878
ISBN 13: 9781118982877
Language: EN, FR, DE, ES & NL

The Human Microbiota and Chronic Disease Book Review:

Microbiota-associated pathology can be a direct result of changes in general bacterial composition, such as might be found in periodontitis and bacterial vaginosis, and/or as the result of colonization and/or overgrowth of so called keystone species. The disruption in the composition of the normal human microbiota, or dysbiosis, plays an integral role in human health and human disease. The Human Microbiota and Human Chronic Disease: Dysbioses as a Cause of Human Pathology discusses the role of the microbiota in maintaining human health. The text introduces the reader to the biology of microbial dysbiosis and its potential role in both bacterial disease and in idiopathic chronic disease states. Divided into five sections, the text delineates the concept of the human bacterial microbiota with particular attention being paid to the microbiotae of the gut, oral cavity and skin. A key methodology for exploring the microbiota, metagenomics, is also described. The book then shows the reader the cellular, molecular and genetic complexities of the bacterial microbiota, its myriad connections with the host and how these can maintain tissue homeostasis. Chapters then consider the role of dysbioses in human disease states, dealing with two of the commonest bacterial diseases of humanity – periodontitis and bacterial vaginosis. The composition of some, if not all microbiotas can be controlled by the diet and this is also dealt with in this section. The discussion moves on to the major ‘idiopathic’ diseases afflicting humans, and the potential role that dysbiosis could play in their induction and chronicity. The book then concludes with the therapeutic potential of manipulating the microbiota, introducing the concepts of probiotics, prebiotics and the administration of healthy human faeces (faecal microbiota transplantation), and then hypothesizes as to the future of medical treatment viewed from a microbiota-centric position. Provides an introduction to dysbiosis, or a disruption in the composition of the normal human microbiota Explains how microbiota-associated pathology and other chronic diseases can result from changes in general bacterial composition Explores the relationship humans have with their microbiota, and its significance in human health and disease Covers host genetic variants and their role in the composition of human microbial biofilms, integral to the relationship between human health and human disease Authored and edited by leaders in the field, The Human Microbiota and Human Chronic Disease will be an invaluable resource for clinicians, pathologists, immunologists, cell and molecular biologists, biochemists, and system biologists studying cellular and molecular bases of human diseases.

Molecular Pathogenesis of Colorectal Cancer

Molecular Pathogenesis of Colorectal Cancer
Author: Kevin M. Haigis, Ph.D.
Publsiher: Springer Science & Business Media
Total Pages: 316
Release: 2013-10-02
ISBN 10: 146148412X
ISBN 13: 9781461484127
Language: EN, FR, DE, ES & NL

Molecular Pathogenesis of Colorectal Cancer Book Review:

Colorectal cancer has for more than two decades served as the paradigm for the multi-step concept of cancer initiation and progression. Perhaps more than any other organ site, cancer of the colon is extensively characterized at the molecular level. We are now entering a time when molecular classification, rather than histologic classification, of cancer subtypes is driving the development of clinical trials with emerging targeted therapies. The book will focus on the progression from the identification of mutations that drive colorectal cancer initiation and progression to the search for novel therapies to treat the disease.

Environmental Chemicals the Human Microbiome and Health Risk

Environmental Chemicals  the Human Microbiome  and Health Risk
Author: National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Board on Life Sciences,Board on Environmental Studies and Toxicology,Committee on Advancing Understanding of the Implications of Environmental-Chemical Interactions with the Human Microbiome
Publsiher: National Academies Press
Total Pages: 122
Release: 2018-03-01
ISBN 10: 0309468698
ISBN 13: 9780309468695
Language: EN, FR, DE, ES & NL

Environmental Chemicals the Human Microbiome and Health Risk Book Review:

A great number of diverse microorganisms inhabit the human body and are collectively referred to as the human microbiome. Until recently, the role of the human microbiome in maintaining human health was not fully appreciated. Today, however, research is beginning to elucidate associations between perturbations in the human microbiome and human disease and the factors that might be responsible for the perturbations. Studies have indicated that the human microbiome could be affected by environmental chemicals or could modulate exposure to environmental chemicals. Environmental Chemicals, the Human Microbiome, and Health Risk presents a research strategy to improve our understanding of the interactions between environmental chemicals and the human microbiome and the implications of those interactions for human health risk. This report identifies barriers to such research and opportunities for collaboration, highlights key aspects of the human microbiome and its relation to health, describes potential interactions between environmental chemicals and the human microbiome, reviews the risk-assessment framework and reasons for incorporating chemicalâ€"microbiome interactions.

Intestinal Microbiota in Health and Disease

Intestinal Microbiota in Health and Disease
Author: Eduardo J. Schiffrin,Philippe Marteau,Dominique Brassart
Publsiher: CRC Press
Total Pages: 344
Release: 2014-02-11
ISBN 10: 1482226774
ISBN 13: 9781482226775
Language: EN, FR, DE, ES & NL

Intestinal Microbiota in Health and Disease Book Review:

Now considered an organ with defensive and metabolic capabilities, the intestinal microbiota plays a major role in the local host immune system development and education. It contributes to the generation of a homeostatic balance characterized by the capacity to react against pathogens while remaining hyperresponsive/tolerant against commensals. This homeostatic response depends on bacteria and bacterial product sensing by innate immune cells and their molecular asset at the intestinal mucosa. This book captures the enormous progress that has been accomplished in this field in recent years.

The Microbiome Diet

The Microbiome Diet
Author: Raphael Kellman
Publsiher: Da Capo Lifelong Books
Total Pages: 272
Release: 2014-07-01
ISBN 10: 0738217662
ISBN 13: 9780738217666
Language: EN, FR, DE, ES & NL

The Microbiome Diet Book Review:

The groundbreaking program that connects the microbiome and gut health to healthy weight loss, complete with a 3-phase plan and recipes Cutting-edge science has shown that the microbiome is the key to overall mental and physical health--and the secret behind healthy, sustainable weight loss. Drawing on nearly two decades of experience as a specialist in functional medicine and intestinal health, Dr. Raphael Kellman has developed the first diet based on these scientific breakthroughs. Offering a proven program to heal your gut and reset your metabolism, along with meal plans and 50 delicious chef-created recipes, The Microbiome Diet is the key to safe, sustainable weight loss and a lifetime of good health. "Dr. Kellman masterfully presents a life enhancing, actionable plan based on this emerging science in a way that is user-friendly, for all of us." --Dr. David Perlmutter, New York Times bestselling author of Grain Brain

Cancer Statistics Review

Cancer Statistics Review
Author: Anonim
Publsiher: Unknown
Total Pages: 135
Release: 1973
ISBN 10: 1928374650XXX
ISBN 13: UCLA:L0061459350
Language: EN, FR, DE, ES & NL

Cancer Statistics Review Book Review:

The Gut Microbiome

The Gut Microbiome
Author: Gyula Mozsik
Publsiher: BoD – Books on Demand
Total Pages: 112
Release: 2016-11-02
ISBN 10: 9535127500
ISBN 13: 9789535127505
Language: EN, FR, DE, ES & NL

The Gut Microbiome Book Review:

In the last decades, the importance of gut microbiome has been linked to medical research on different diseases. Developments of other medical disciplines (human clinical pharmacology, clinical nutrition and dietetics, everyday medical treatments of antibiotics, changes in nutritional inhabits in different countries) also called attention to study the changes in the gut microbiome. This book contains five excellent review chapters in the field of gut microbiome, written by researchers from the USA, Canada, China, and India. These chapters present a critical review about some clinically important changes in the gut microbiome in the development of some human diseases and therapeutic possibilities (liver disease, cardiovascular diseases, brain diseases, gastrointestinal diseases). The book brings to attention the essential role of gut microbiome in keeping our life healthy. This book is addressed to experts of microbiology, podiatrists, gastroenterologists, internists, nutritional experts, cardiologists, basic and clinical researchers, as well as experts in the field of food industry.