Clinical Trial Design Challenges in Mood Disorders

Clinical Trial Design Challenges in Mood Disorders
Author: Mauricio Tohen,Charles Bowden,Andrew A. Nierenberg,John Geddes
Publsiher: Academic Press
Total Pages: 192
Release: 2015-01-24
ISBN 10: 0124051766
ISBN 13: 9780124051768
Language: EN, FR, DE, ES & NL

Clinical Trial Design Challenges in Mood Disorders Book Review:

Poor clinical trial designs result in failed studies wasting research funds and limiting the advancement of cures for disorders. Clinical Trial Design Challenges in Mood Disorders outlines classic problems researchers face in designing clinical trials and discusses how best to address them for the most definitive and generalizable results. Traditional trial designs are included as well as novel analytic techniques. The book examines information on high placebo response, the generalizability of studies conducted in the developing world, the duration of maintenance studies, and the application of findings into clinical practice. With representation from contributors throughout the world and from academia, industry, regulatory agencies, and advocacy groups, this book will contribute toward improved clinical trial design and valid, precise, and reliable answers about what works better and faster for patients. Summarizes common trial design problems and their solutions Encompasses funding, subject selection, regulatory issues and more Identifies best practices for definitive and generalizable results Includes traditional trial designs and novel analytic techniques Represents academia, industry, regulatory agencies, and advocacy groups

Neuroscience Trials of the Future

Neuroscience Trials of the Future
Author: National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Sciences Policy,Forum on Neuroscience and Nervous System Disorders
Publsiher: National Academies Press
Total Pages: 110
Release: 2016-11-07
ISBN 10: 0309442583
ISBN 13: 9780309442589
Language: EN, FR, DE, ES & NL

Neuroscience Trials of the Future Book Review:

On March 3-4, 2016, the National Academies of Sciences, Engineering, and Medicine's Forum on Neuroscience and Nervous System Disorders held a workshop in Washington, DC, bringing together key stakeholders to discuss opportunities for improving the integrity, efficiency, and validity of clinical trials for nervous system disorders. Participants in the workshop represented a range of diverse perspectives, including individuals not normally associated with traditional clinical trials. The purpose of this workshop was to generate discussion about not only what is feasible now, but what may be possible with the implementation of cutting-edge technologies in the future.

Clinical Trials in Older Adults

Clinical Trials in Older Adults
Author: Antonio Cherubini,Roberto Bernabei,Luigi Ferrucci,Niccolò Marchionni,Stephanie Studenski,Bruno Vellas
Publsiher: John Wiley & Sons
Total Pages: 280
Release: 2016-01-13
ISBN 10: 1118323475
ISBN 13: 9781118323472
Language: EN, FR, DE, ES & NL

Clinical Trials in Older Adults Book Review:

Clinical Trials in Older Adults is the first book to consider the methodological issues underlying the evaluation of new treatments in older people. Provides information on the methodology, monitoring and regulations for those planning to conduct a clinical trials involving older adults Contains examples of ongoing trials involving older adults, and presents the main characteristics of many recently published Depicts how the issues regarding older adults in clinical trials could be properly addressed with the appropriate study design and conduct Identifies key issues in performing clinical trials in older patients with common geriatric conditions, i.e. Alzheimer’s dementia, depression, low muscle mass, cancer

Behavioral Clinical Trials for Chronic Diseases

Behavioral Clinical Trials for Chronic Diseases
Author: Lynda H. Powell
Publsiher: Springer Nature
Total Pages: 135
Release: 2021
ISBN 10: 3030393305
ISBN 13: 9783030393304
Language: EN, FR, DE, ES & NL

Behavioral Clinical Trials for Chronic Diseases Book Review:

The Medical Basis of Psychiatry

The Medical Basis of Psychiatry
Author: S. Hossein Fatemi,Paula J. Clayton
Publsiher: Springer
Total Pages: 1064
Release: 2016-03-17
ISBN 10: 1493925288
ISBN 13: 9781493925285
Language: EN, FR, DE, ES & NL

The Medical Basis of Psychiatry Book Review:

Four years have passed since the last edition (3rd) of this book was published. In the intervening years, several reviews of this book have provided highly encouraging remarks about the value of this book in transmitting information on classification and treatment of psychiatric disorders to the audience. We are proposing to revise all chapters with an eye on accuracy and ease of use, and this is an especially timely endeavor with the upcoming publication of the Diagnostic and Statistical Manual V. All the appropriate new information on biology, etiology, diagnosis and treatment of psychiatric disorders will be added to the current proposed edition. It is our goal to recruit the same authors (if possible) who contributed to the previous edition. While all chapters will be updated (see TOC), those marked by asterisks will be the most likely to undergo more revision. Psychiatry has emerged as a burgeoning scientific field with major advances in etiology and treatment of several disorders. Just as there was excitement in the anatomic advances that took place a hundred years ago when Emil Kraepelin and his collaborators took on the enormous task of classification of psychiatric disorders based on rational scientific thinking, new advances in genetics, biochemistry, neuroanatomy and pharmacotherapy of mental disorders have brought us even closer to a better understanding of complex disorders like schizophrenia, bipolar disorder, depression and even autism. The major goal of the previous edition of this classic book was to update the busy clinician, psychiatric resident and medical student with the most up-to-date information on etiology, diagnosis and treatment of psychiatric disorders. This goal remains the focus of the fourth edition of this book. In this updated and expanded edition, the reader will be provided with the most contemporary information and literature supported by a close survey of the field. This new edition of this classic title, with its focus on biologic and medical aspects of psychiatry, will continue to be of significant help to all interested in the scientific practice of psychiatry.

Understanding Research for Nursing Students

Understanding Research for Nursing Students
Author: Peter Ellis
Publsiher: Learning Matters
Total Pages: 208
Release: 2018-10-29
ISBN 10: 1526459698
ISBN 13: 9781526459695
Language: EN, FR, DE, ES & NL

Understanding Research for Nursing Students Book Review:

If you’re learning about research for the first time, or grappling with an essay or final year project, this is the nursing research book you’re looking for. Using plain language and case studies that relate research directly to every-day nursing situations, the author guides you through the central concepts you need to know to truly understand research in nursing. Key features Each chapter is linked to the new NMC standards of proficiency for registered nurses Seven concise chapters that quickly answer the most common questions about research Activities, scenarios and case studies bring the theory to life and show why research is so important to nursing Nine podcasts to bring topics from the book to life

Improving and Accelerating Therapeutic Development for Nervous System Disorders

Improving and Accelerating Therapeutic Development for Nervous System Disorders
Author: Institute of Medicine,Board on Health Sciences Policy,Forum on Neuroscience and Nervous System Disorders
Publsiher: National Academies Press
Total Pages: 118
Release: 2014-02-06
ISBN 10: 0309292492
ISBN 13: 9780309292498
Language: EN, FR, DE, ES & NL

Improving and Accelerating Therapeutic Development for Nervous System Disorders Book Review:

Improving and Accelerating Therapeutic Development for Nervous System Disorders is the summary of a workshop convened by the IOM Forum on Neuroscience and Nervous System Disorders to examine opportunities to accelerate early phases of drug development for nervous system drug discovery. Workshop participants discussed challenges in neuroscience research for enabling faster entry of potential treatments into first-in-human trials, explored how new and emerging tools and technologies may improve the efficiency of research, and considered mechanisms to facilitate a more effective and efficient development pipeline. There are several challenges to the current drug development pipeline for nervous system disorders. The fundamental etiology and pathophysiology of many nervous system disorders are unknown and the brain is inaccessible to study, making it difficult to develop accurate models. Patient heterogeneity is high, disease pathology can occur years to decades before becoming clinically apparent, and diagnostic and treatment biomarkers are lacking. In addition, the lack of validated targets, limitations related to the predictive validity of animal models - the extent to which the model predicts clinical efficacy - and regulatory barriers can also impede translation and drug development for nervous system disorders. Improving and Accelerating Therapeutic Development for Nervous System Disorders identifies avenues for moving directly from cellular models to human trials, minimizing the need for animal models to test efficacy, and discusses the potential benefits and risks of such an approach. This report is a timely discussion of opportunities to improve early drug development with a focus toward preclinical trials.

Healthy Aging

Healthy Aging
Author: Patrick P. Coll
Publsiher: Springer
Total Pages: 399
Release: 2019-03-29
ISBN 10: 3030062007
ISBN 13: 9783030062002
Language: EN, FR, DE, ES & NL

Healthy Aging Book Review:

This book weaves all of these factors together to engage in and promote medical, biomedical and psychosocial interventions, including lifestyle changes, for healthier aging outcomes. The text begins with an introduction to age-related changes that increase in disease and disability commonly associated with old age. Written by experts in healthy aging, the text approaches the principles of disease and disability prevention via specific health issues. Each chapter highlights the challenge of not just increasing life expectancy but also deceasing disease burden and disability in old age. The text then shifts into the whole-person implications for clinicians working with older patients, including the social and cultural considerations that are necessary for improved outcomes as Baby Boomers age and healthcare systems worldwide adjust. Healthy Aging is an important resource for those working with older patients, including geriatricians, family medicine physicians, nurses, gerontologists, students, public health administrators, and all other medical professionals.

The Ethical Challenges of Emerging Medical Technologies

The Ethical Challenges of Emerging Medical Technologies
Author: Arthur L. Caplan,Brendan Parent
Publsiher: Routledge
Total Pages: 482
Release: 2020-09-10
ISBN 10: 1000151999
ISBN 13: 9781000151992
Language: EN, FR, DE, ES & NL

The Ethical Challenges of Emerging Medical Technologies Book Review:

This collection of essays emphasizes society’s increasingly responsible engagement with ethical challenges in emerging medical technology. Expansion of technological capacity and attention to patient safety have long been integral to improving healthcare delivery but only relatively recently have concepts like respect, distributive justice, privacy, and autonomy gained some power to shape the development, use, and refinement of medical tools and techniques. Medical ethics goes beyond making better medicine to thinking about how to make the field of medicine better. These essays showcase several ways in which modern ethical thinking is improving safety, efficacy and efficiency of medical technology, increasing access to medical care, and empowering patients to choose care that comports with their desires and beliefs. Included are complimentary ethical approaches as well as compelling counter-arguments. Together, the articles demonstrate how improving the quality of medical technology relies on every stakeholder -- not just medical researchers and scientists -- to assess each given technology’s strengths and pitfalls. This collection also portends one of the next major issues in the ethics of medical technology: developing the requisite moral framework to accompany shifts toward patient-centred personalized healthcare.

Pocket Psychiatry

Pocket Psychiatry
Author: John B. Taylor,Judith Puckett
Publsiher: Lippincott Williams & Wilkins
Total Pages: 350
Release: 2019-03-21
ISBN 10: 1975117948
ISBN 13: 9781975117948
Language: EN, FR, DE, ES & NL

Pocket Psychiatry Book Review:

Pocket Psychiatry, a new addition to the Pocket Notebook series, is written by residents for residents. A resource for essential information, in a high-yield, easy-to-use format, designed to help students, trainees, and others navigate the initial psychiatric evaluation and management of the most commonly encountered psychiatric conditions. With an emphasis on evidence-based information, Pocket Psychiatry, provides a rare concise and accessible resource, for must-know information on hospital- and clinic-based psychiatric care — from history and physical exam to differential diagnosis testing to therapeutics — in the well known loose leaf pocket size format.

Posttraumatic Stress and Substance Use Disorders

Posttraumatic Stress and Substance Use Disorders
Author: Anka A. Vujanovic,Sudie E. Back
Publsiher: Routledge
Total Pages: 376
Release: 2019-04-23
ISBN 10: 1315442620
ISBN 13: 9781315442624
Language: EN, FR, DE, ES & NL

Posttraumatic Stress and Substance Use Disorders Book Review:

Posttraumatic Stress and Substance Use Disorders summarizes the state of the field from a biopsychosocial perspective, addressing key domains of interest to clinicians, students, instructors, and researchers. This book is a valuable resource and reference guide for multidisciplinary practitioners and scientists interested in the evidence-based assessment and treatment of posttraumatic stress and substance use disorders. Chapters written by leaders in the field cover the latest research on assessment, diagnosis, evidence-based treatments, future directions, and much more.

Cognitive Enhancement in CNS Disorders and Beyond

Cognitive Enhancement in CNS Disorders and Beyond
Author: Richard S. E. Keefe,Avi (Abraham) Reichenberg,Jeffrey Cummings
Publsiher: Oxford University Press
Total Pages: 448
Release: 2017
ISBN 10: 0190214406
ISBN 13: 9780190214401
Language: EN, FR, DE, ES & NL

Cognitive Enhancement in CNS Disorders and Beyond Book Review:

Cognitive Enhancement in CNS Disorders and Beyond compiles a series of educational and thought-provoking chapters from the world's leading cognitive and clinical scientists to describe the latest research on cognitive impairments in a host of pathological conditions that affect CNS functioning, what treatments are available for these impairments, and how new treatments are being tested. This volume will benefit any investigators in cognitive science and clinical research, but is also accessible to non-experts. It advances the field toward the availability of cognitive enhancing drugs and devices that will benefit those who need them most and others who may feel that these techniques can help them to thrive. There has never been a time that we knew more about cognition and never a time when cognition was more important to the functioning of human beings than right now. Psychological science and cognitive neuroscience have become the most popular endeavor of students world wide, is the focus of attention of our greatest scientific accomplishments and the emphasis of many publications in the mainstream media. Since humans depend on cognitive abilities for survival, quality of life, and productivity, improving it has never been more important. Those with impairments in key aspects of cognition suffer dearly, as they are unable to obtain and retain information, unable to make sound decisions based upon the information at hand, and unable to plan future activities. The availability of pharmacological and behavioral interventions that can improve cognitive abilities and provide impaired individuals with the social, occupational and functional quality of life that the rest of us enjoy has potential far-reaching implications. Such interventions can also benefit those who want to boost current cognitive abilities to higher levels, perhaps as a means to hone skills in providing products for others or to gain an edge on competition. There has never been a book devoted solely to describing the latest cognitive science and neuroscience on the methods for enhancing cognition in healthy and unhealthy humans. Cognitive Enhancement in CNS Disorders and Beyond accomplishes exactly that in a straightforward and accessible manner.

Clinical Guide to Depression and Bipolar Disorder

Clinical Guide to Depression and Bipolar Disorder
Author: Martin B. Keller,William H. Coryell,Jean Endicott,Jack D. Maser,Pamela J. Schettler
Publsiher: American Psychiatric Pub
Total Pages: 234
Release: 2013-04-10
ISBN 10: 1585629944
ISBN 13: 9781585629947
Language: EN, FR, DE, ES & NL

Clinical Guide to Depression and Bipolar Disorder Book Review:

Conceived in the early 1970s to study the phenomenology, diagnosis, genetics, and clinical course of depression, the NIMH Collaborative Depression Study (CDS) has influenced research and practice since its inception. Clinical Guide to Depression and Bipolar Disorder: Findings From the Collaborative Depression Study summarizes key findings from the study and the related literature to provide comprehensive and up-to-date knowledge on the course and outcome of illness in mood disorders. Nowhere else can clinicians find such detailed longitudinal data, combined with astute clinical analysis of the current research. The volume offers: Historical background on how psychodynamic psychiatry was overtaken by psychobiological perspectives, and the challenges and controversies that gave rise to the CDS, providing the context necessary to understand the profession's development to the present day. A wealth of information on nosology, natural history, phenomenology, and treatment response in depressive and bipolar disorders. Detailed descriptions of the study methods employed, providing information and insights that will assist researchers in the longitudinal design of prospective cohort studies. Comprehensive review of outcomes in mood disorder, including delineation of the long-term course of bipolar I, bipolar II, and unipolar major depressive disorders, the implications of which will continue to be instrumental in the development of psychiatric nosology and indispensable to clinicians engaged in assessment and treatment. Critical information clinicians need in order to read the clinical signs in their patients and predict the "switch" from unipolar to bipolar disorder. A fascinating review of the evolution of diagnostic thinking about the role of anxiety in mood disorders, and the contributions of the CDS to the newly published DSM-5®. Each chapter is accompanied by a time-saving summary, as well as a section on clinical implications that translates the findings into practical points and key recommendations clinicians need to know to provide optimal care. Psychiatrists, clinical psychologists, residents, and fellows will turn to Clinical Guide to Depression and Bipolar Disorder: Findings From the Collaborative Depression Study to better understand the course and outcome of their patients' mood disorders and, ultimately, to improve their clinical skills.

The American Psychiatric Association Practice Guidelines for the Psychiatric Evaluation of Adults Third Edition

The American Psychiatric Association Practice Guidelines for the Psychiatric Evaluation of Adults  Third Edition
Author: American Psychiatric Association
Publsiher: American Psychiatric Pub
Total Pages: 170
Release: 2015-07-29
ISBN 10: 0890424659
ISBN 13: 9780890424650
Language: EN, FR, DE, ES & NL

The American Psychiatric Association Practice Guidelines for the Psychiatric Evaluation of Adults Third Edition Book Review:

Since the publication of the Institute of Medicine (IOM) report Clinical Practice Guidelines We Can Trust in 2011, there has been an increasing emphasis on assuring that clinical practice guidelines are trustworthy, developed in a transparent fashion, and based on a systematic review of the available research evidence. To align with the IOM recommendations and to meet the new requirements for inclusion of a guideline in the National Guidelines Clearinghouse of the Agency for Healthcare Research and Quality (AHRQ), American Psychiatric Association (APA) has adopted a new process for practice guideline development. Under this new process APA's practice guidelines also seek to provide better clinical utility and usability. Rather than a broad overview of treatment for a disorder, new practice guidelines focus on a set of discrete clinical questions of relevance to an overarching subject area. A systematic review of evidence is conducted to address these clinical questions and involves a detailed assessment of individual studies. The quality of the overall body of evidence is also rated and is summarized in the practice guideline. With the new process, recommendations are determined by weighing potential benefits and harms of an intervention in a specific clinical context. Clear, concise, and actionable recommendation statements help clinicians to incorporate recommendations into clinical practice, with the goal of improving quality of care. The new practice guideline format is also designed to be more user friendly by dividing information into modules on specific clinical questions. Each module has a consistent organization, which will assist users in finding clinically useful and relevant information quickly and easily. This new edition of the practice guidelines on psychiatric evaluation for adults is the first set of the APA's guidelines developed under the new guideline development process. These guidelines address the following nine topics, in the context of an initial psychiatric evaluation: review of psychiatric symptoms, trauma history, and treatment history; substance use assessment; assessment of suicide risk; assessment for risk of aggressive behaviors; assessment of cultural factors; assessment of medical health; quantitative assessment; involvement of the patient in treatment decision making; and documentation of the psychiatric evaluation. Each guideline recommends or suggests topics to include during an initial psychiatric evaluation. Findings from an expert opinion survey have also been taken into consideration in making recommendations or suggestions. In addition to reviewing the available evidence on psychiatry evaluation, each guideline also provides guidance to clinicians on implementing these recommendations to enhance patient care.

Transforming Clinical Research in the United States

Transforming Clinical Research in the United States
Author: Institute of Medicine,Board on Health Sciences Policy,Forum on Drug Discovery, Development, and Translation
Publsiher: National Academies Press
Total Pages: 150
Release: 2010-10-22
ISBN 10: 9780309163354
ISBN 13: 0309163358
Language: EN, FR, DE, ES & NL

Transforming Clinical Research in the United States Book Review:

An ideal health care system relies on efficiently generating timely, accurate evidence to deliver on its promise of diminishing the divide between clinical practice and research. There are growing indications, however, that the current health care system and the clinical research that guides medical decisions in the United States falls far short of this vision. The process of generating medical evidence through clinical trials in the United States is expensive and lengthy, includes a number of regulatory hurdles, and is based on a limited infrastructure. The link between clinical research and medical progress is also frequently misunderstood or unsupported by both patients and providers. The focus of clinical research changes as diseases emerge and new treatments create cures for old conditions. As diseases evolve, the ultimate goal remains to speed new and improved medical treatments to patients throughout the world. To keep pace with rapidly changing health care demands, clinical research resources need to be organized and on hand to address the numerous health care questions that continually emerge. Improving the overall capacity of the clinical research enterprise will depend on ensuring that there is an adequate infrastructure in place to support the investigators who conduct research, the patients with real diseases who volunteer to participate in experimental research, and the institutions that organize and carry out the trials. To address these issues and better understand the current state of clinical research in the United States, the Institute of Medicine's (IOM) Forum on Drug Discovery, Development, and Translation held a 2-day workshop entitled Transforming Clinical Research in the United States. The workshop, summarized in this volume, laid the foundation for a broader initiative of the Forum addressing different aspects of clinical research. Future Forum plans include further examining regulatory, administrative, and structural barriers to the effective conduct of clinical research; developing a vision for a stable, continuously funded clinical research infrastructure in the United States; and considering strategies and collaborative activities to facilitate more robust public engagement in the clinical research enterprise.

The Bipolar Book

The Bipolar Book
Author: Aysegul Yildiz,Pedro Ruiz,Charles Nemeroff
Publsiher: Oxford University Press
Total Pages: 720
Release: 2015-05-22
ISBN 10: 0199300542
ISBN 13: 9780199300549
Language: EN, FR, DE, ES & NL

The Bipolar Book Book Review:

As a major mainstay of clinical focus and research today, bipolar disorder affects millions of individuals across the globe with its extreme and erratic shifts of mood, thinking and behavior. Edited by a team of experts in the field, The Bipolar Book: History, Neurobiology, and Treatment is a testament and guide to diagnosing and treating this exceedingly complex, highly prevalent disease. Featuring 45 chapters from an expert team of contributors from around the world, The Bipolar Book delves deep into the origins of the disorder and how it informs clinical practice today by focusing on such topics as bipolar disorder occurring in special populations, stigmatization of the disease, the role genetics play, postmortem studies, psychotherapy, treatments and more. Designed to be the definitive reference volume for clinicians, students and researchers, Aysegül Yildiz, Pedro Ruiz and Charles Nemeroff present The Bipolar Book as a "must have" for those caregivers who routinely deal with this devastating disease.

The American Psychiatric Publishing Textbook of Mood Disorders

The American Psychiatric Publishing Textbook of Mood Disorders
Author: Dan J. Stein,David J. Kupfer,Alan F. Schatzberg
Publsiher: American Psychiatric Pub
Total Pages: 792
Release: 2007-05-03
ISBN 10: 158562716X
ISBN 13: 9781585627165
Language: EN, FR, DE, ES & NL

The American Psychiatric Publishing Textbook of Mood Disorders Book Review:

Psychiatrists and other mental health care and medical professionals can now turn to a truly authoritative, up-to-date reference for current information about mood disorders. The American Psychiatric Publishing Textbook of Mood Disorders -- including a wealth of illustrations, tables and references -- presents the state of the art in diagnosis, psychobiology, pharmacotherapy, and psychotherapy across the vast spectrum of mood disorders: Symptomatology and Epidemiology: historical aspects and social underpinnings of mood disorders, classification and rating scales, and global burden Pathogenesis: neurochemistry and psychoneuroendocrinology, cognitive processing models (experimental cognitive research), and evolutionary explanations Methods of Investigation:anatomical pathology, molecular and cellular neurobiology of severe mood disorders, and genetics of bipolar and unipolar disorders Types of Mood Disorder: psychotic depression, seasonal affective disorder, secondary depression with medical illness, major depression seen in primary care, and substance abuse, and sleep disorders Treatments: pharmacotherapy, brain stimulation techniques, and psychotherapies Pertinent Factors: personality, culture, and gender Offering a fascinating synthesis of the multifaceted field of mood disorders, the richly informative American Psychiatric Publishing Textbook of Mood Disorders will prove invaluable for psychiatric and medical practitioners, educators, students, and residents interested in the latest breakthroughs in the diagnosis, treatment, and management of mood disorders.

Bipolar Disorder Vulnerability

Bipolar Disorder Vulnerability
Author: Jair Soares,Consuelo Walss-Bass,Paolo Brambilla
Publsiher: Academic Press
Total Pages: 288
Release: 2018-06-09
ISBN 10: 0128125608
ISBN 13: 9780128125601
Language: EN, FR, DE, ES & NL

Bipolar Disorder Vulnerability Book Review:

Bipolar Disorder Vulnerability: Perspectives from Pediatric and High-Risk Populations synthesizes our current understanding of high-risk and pediatric populations to aid readers in identifying markers of vulnerability for the development of bipolar disorder, with an ultimate goal of the development of drug targets and other therapies for early diagnosis and treatment. The book provides readers with an understanding of biological and environmental factors influencing disease manifestation that will aid them in defining discrete clinical stages and, importantly, establish an empirical basis for the application of novel therapeutics in a phase of illness during which specific treatments could more effectively alter disease course. Whereas most of the literature available on the pathophysiological mechanisms of bipolar disorder focuses on chronically ill adult individuals, this represents the only book that specifically examines pediatric and high-risk populations. An estimated 30 to 60 percent of adult bipolar disorder patients have their disease onset during childhood, with early-onset cases representing a particularly severe and genetically loaded form of the illness. Highlights diverse translational methodologies, including functional and structural neuroimaging, neuropsychological testing and integrated genomics Examines molecular trajectories in youth with bipolar disorder and unaffected youth at high risk for developing bipolar disorder Explores the interaction between genomic and environmental influences that shape behavior

Mood Disorders

Mood Disorders
Author: Mick Power
Publsiher: John Wiley & Sons
Total Pages: 394
Release: 2004-03-05
ISBN 10: 0470092769
ISBN 13: 9780470092767
Language: EN, FR, DE, ES & NL

Mood Disorders Book Review:

"This Handbook gives an outstanding overview of the accomplishments to date and a sense of the excitement to come." Kay Redfield Jamison, Foreword Mood Disorders: A Handbook of Science and Practice provides an up-to-date summary of the latest theory and practice in unipolar and bipolar mood disorders. This comprehensive volume focuses on innovations in both science and clinical practice, and considers new pharmacological treatments as well as psychological therapies. With contributions from the worldâ??s leading authorities on mood disorders, all clinical psychologists and psychiatrists in practice and training will find this book an authoritative reference tool.

Ketamine for Treatment Resistant Depression

Ketamine for Treatment Resistant Depression
Author: Gustavo H. Vazquez,Carlos A. Zarate,Elisa Brietzke
Publsiher: Academic Press
Total Pages: 168
Release: 2020-09-16
ISBN 10: 0128210346
ISBN 13: 9780128210345
Language: EN, FR, DE, ES & NL

Ketamine for Treatment Resistant Depression Book Review:

Ketamine for Treatment-Resistant Depression: Neurobiology and Applications provides a simple, evidence-based overview for neuropsychiatrists and translational researchers on this medication, its mechanisms of actions, eligibility of patients for treatment, and the preparation and implementation of ketamine clinics. Provides efficacy research on ketamine as a treatment for depression Identifies best practices for clinical use, both long-term and acute Discusses the molecular mechanisms and neurobiology of action