Clinical Molecular Medicine

Clinical Molecular Medicine
Author: Dhavendra Kumar
Publsiher: Academic Press
Total Pages: 606
Release: 2019-11-30
ISBN 10: 0128094427
ISBN 13: 9780128094426
Language: EN, FR, DE, ES & NL

Clinical Molecular Medicine Book Review:

Clinical Molecular Medicine: Principles and Practice presents the latest scientific advances in molecular and cellular biology, including the development of new and effective drug and biological therapies and diagnostic methods. The book provides medical and biomedical students and researchers with a clear and clinically relevant understanding on the molecular basis of human disease. With an increased focus on new practice concepts, such as stratified, personalized and precision medicine, this book is a valuable and much-needed resource that unites the core principles of molecular biology with the latest and most promising genomic advances. Illustrates the fundamental principles and therapeutic applications of molecular and cellular biology Offers a clinically focused account of molecular heterogeneity Includes comprehensive coverage of many different disorders, including growth and development, cardiovascular, metabolic, skin, blood, digestive, inflammatory, neuropsychiatric disorders, and many more

Molecular Medicine

Molecular Medicine
Author: Jens Kurreck,Cy Aaron Stein
Publsiher: John Wiley & Sons
Total Pages: 404
Release: 2016-02-16
ISBN 10: 3527331891
ISBN 13: 9783527331895
Language: EN, FR, DE, ES & NL

Molecular Medicine Book Review:

Easy to read, yet comprehensive, this is the perfect introduction into the molecular basis of disease and the novel treatment options that have become available. The authors, Jens Kurreck and Cy Stein, have both long-standing teaching experience on the subject, one from a biologist's angle, the other with a medical background. Together, they have produced a modern textbook for courses in Molecular Medicine that incorporates modules from immunology to signaling, from virology to gene therapy, and the latest development in personalized medicine.

Modern Clinical Molecular Techniques

Modern Clinical Molecular Techniques
Author: Peter Hu,Madhuri Hegde,Patrick Alan Lennon
Publsiher: Springer Science & Business Media
Total Pages: 436
Release: 2012-05-11
ISBN 10: 1461421705
ISBN 13: 9781461421702
Language: EN, FR, DE, ES & NL

Modern Clinical Molecular Techniques Book Review:

This timely book covers the need to know clinical practices for all those involved in molecular laboratory science. The field of molecular medicine is evolving at an astounding speed. Propelled by the new insights and technologies, advances are being made at an unprecedented rate. With dual measure given to today’s breakthroughs, this book is a collection of the most current practices relevant to the clinical molecular laboratorian. It begins with an introductory section on techniques and procedure. It then presents four separate sections on infectious disease, oncology, pre/post-natal, and identity testing, with specific chapters clearly outlining clinical protocols used in daily practice. Modern Clinical Molecular Techniques cuts to the heart of what is essential for the practicing molecular laboratory scientist. It is an outstanding resource for those operating within or looking to set up a clinical molecular laboratory.

Principles of Molecular Cardiology

Principles of Molecular Cardiology
Author: Marschall S. Runge,Cam Patterson
Publsiher: Springer Science & Business Media
Total Pages: 617
Release: 2007-11-14
ISBN 10: 1592598781
ISBN 13: 9781592598786
Language: EN, FR, DE, ES & NL

Principles of Molecular Cardiology Book Review:

An easy-to-read survey of all the latest developments in molecular cardiologic research and therapy. The authors explain in a readable style the complex process of the heart's development, the molecular basis of cardiovascular diseases, and the translation of these research advances to actual clinical treatments. The expert information provided here serves as an invaluable building block for novel treatments of cardiovascular diseases and includes a comprehensive discussion of cardiac function and dysfunction, coronary artery disease, cardiac arrhythmias, vascular diseases, and risk factors for cardiovascular disease. These state-of-the-art approaches to molecular cardiologic research include critical discussion of such topics as the molecular events that regulate angiogenesis and the potential for angiogenic therapy, emerging therapies for arrhythmias, and a description of the molecular biology of aging and its impact on the cardiovascular system.

Self assessment Questions for Clinical Molecular Genetics

Self assessment Questions for Clinical Molecular Genetics
Author: Haiying Meng
Publsiher: Academic Press
Total Pages: 816
Release: 2019-05-28
ISBN 10: 0128099682
ISBN 13: 9780128099681
Language: EN, FR, DE, ES & NL

Self assessment Questions for Clinical Molecular Genetics Book Review:

Review Questions of Clinical Molecular Genetics presents a comprehensive study guide for the board and certificate exams presented by the American College of Medical Genetics and Genomics (ACMG) and the American Board of Medical Genetics and Genomics (ABMGG). It provides residents and fellows in genetics and genomics with over 1,000 concise questions, ranging from topics in cystic fibrosis, to genetic counseling, to trinucleotide repeat expansion disorders. It puts key points in the form of questions, thus challenging the reader to retain knowledge. As board and certificate exams require knowledge of new technologies and applications, this book helps users meet that challenge. Includes over 1,0000 multiple-choice, USMLE style questions to help readers prepare for specialty exams in Clinical Cytogenetics and Clinical Molecular Genetics Designed to assist clinical molecular genetic fellows, genetic counselors, medical genetic residents and fellows, and molecular pathologist residents in preparing for their certification exam Assists trainees on how to follow guidelines and put them in practice

Molecular Medicine for Clinicians

Molecular Medicine for Clinicians
Author: Barry Mendelow,Michèle Ramsay,Nanthakumarn Chetty,Wendy Stevens,Patrick Arbuthnot,Silke Arndt,Sahle Asfaha,Jacqueline Brown,Alexio Capovilla,Arnold Christianson,Gerrit Coetzee,Theresa Coetzer,Leandra Cronjé,Nigel Crowther,Chrisna Durandt,Adriano Duse,Lindsay Earlam,Debbie Glencross,Nerine Gregersen,Kate Hammond,Tabitha Haw,Nicole Holland,Penny Keene,Hendrik Koornhof,Amanda Krause,Anthony Lane,Zane Lombard,Elizabeth Mayne,Marion Munster,Grant Napier,Andries Oelofse,Lillian Ouko,Maria Papathanasopoulos,Alan Paterson,Michael Pepper,Wolfgang Prinz,Natela Rekhviashvili,Nerina Savage,Barry Schoub,Lesley Scott,Mieneke Smit van Dixhoorn,Himla Soodyall,Gwynneth Stevens,Ahmed Wadee,Sarah Walters,Marco Weinberg,Natalie Whalley,Tracey Wiggill,Pascale Willem
Publsiher: NYU Press
Total Pages: 531
Release: 2008-10-01
ISBN 10: 1868147134
ISBN 13: 9781868147137
Language: EN, FR, DE, ES & NL

Molecular Medicine for Clinicians Book Review:

This book is suitable for undergraduate medical students, as part of their basic sciences training, but is also relevant to interested under- and postgraduate science and engineering students. There is a special focus on the application of molecular medicine in Africa and in developing countries elsewhere.

Philosophy of Molecular Medicine

Philosophy of Molecular Medicine
Author: Giovanni Boniolo,Marco J. Nathan
Publsiher: Taylor & Francis
Total Pages: 288
Release: 2016-11-18
ISBN 10: 1317378350
ISBN 13: 9781317378358
Language: EN, FR, DE, ES & NL

Philosophy of Molecular Medicine Book Review:

Philosophy of Molecular Medicine: Foundational Issues in Theory and Practice aims at a systematic investigation of a number of foundational issues in the field of molecular medicine. The volume is organized around four broad modules focusing, respectively, on the following key aspects: What are the nature, scope, and limits of molecular medicine? How does it provide explanations? How does it represent and model phenomena of interest? How does it infer new knowledge from data and experiments? The essays collected here, authored by prominent scientists and philosophers of science, focus on a handful of mainstream topics in the philosophical literature, such as causation, explanation, modeling, and scientific inference. These previously unpublished contributions shed new light on these traditional topics by integrating them with problems, methods, and results from three prominent areas of contemporary biomedical science: basic research, translational and clinical research, and clinical practice.

Molecular Medicine

Molecular Medicine
Author: R.J. Trent
Publsiher: Academic Press
Total Pages: 346
Release: 2012-08-22
ISBN 10: 0123814529
ISBN 13: 9780123814524
Language: EN, FR, DE, ES & NL

Molecular Medicine Book Review:

Molecular Medicine is the application of genetic or DNA-based knowledge to the modern practice of medicine. Molecular Medicine, 4e, provides contemporary insights into how the genetic revolution is influencing medical thinking and practice. The new edition includes recent changes in personalized medicine, new growth in omics and direct-to-consumer DNA testing, while focusing on advances in the Human Genome project and implications of the advances in clinical medicine. Graduate students, researchers, clinicians and allied health professionals will appreciate the background history and clinical application of up-to-date molecular advances. Extensively revised to incorporate the results of the Human Genome Project, it provides the latest developments in molecular medicine The only book in Molecular Medicine to reach its fourth edition Identifies current practice as well as future developments Presents extensive tables, well presented figures and resources for further understanding

Molecular Medicine

Molecular Medicine
Author: R.J. Trent
Publsiher: Elsevier
Total Pages: 320
Release: 2005-06-06
ISBN 10: 0080454380
ISBN 13: 9780080454382
Language: EN, FR, DE, ES & NL

Molecular Medicine Book Review:

Molecular medicine is the application of gene or DNA based knowledge to the modern practice of medicine. This book provides contemporary insights into how the genetic revolution is influencing medical thinking and practice on a broad front including clinical medicine, innovative therapies and forensic medicine. * Extensively revised just after the completion of the Human Genome Project, it provides the latest in molecular medicine developments * The only book in Molecular Medicine that has undergone 3 editions * Current practice as well as future developments identified * Extensive tables, well presented figures - resources for further understanding

Principles of Molecular Medicine

Principles of Molecular Medicine
Author: J. Larry Jameson
Publsiher: Springer Science & Business Media
Total Pages: 1127
Release: 1998-07-13
ISBN 10: 1592597262
ISBN 13: 9781592597260
Language: EN, FR, DE, ES & NL

Principles of Molecular Medicine Book Review:

Within the framework of clinical internal medicine, they will gain critical knowledge of the many powerful molecular biology-based developments now so rapidly enhancing our understanding of the pathophysiology of disease, improving the feasibility and accuracy of diagnostic testing, and opening novel therapeutic avenues, including gene therapy. Readers will also gain a fuller understanding of the role played by genetic defects in a host of diseases, among them peripheral neuropathies, Alzheimer's disease, arrhythmias, leukemias and lymphomas, cystic fibrosis, hepatitis, HIV, autoimmune disorders, polycystic kidney disease, schizophrenia, affective disorders, alcoholism, Huntington's disease, and many more.

Molecular Pathology

Molecular Pathology
Author: William B. Coleman,Gregory J. Tsongalis
Publsiher: Academic Press
Total Pages: 802
Release: 2017-11-09
ISBN 10: 0128027878
ISBN 13: 9780128027875
Language: EN, FR, DE, ES & NL

Molecular Pathology Book Review:

As the molecular basis of human disease becomes better characterized, and the implications for understanding the molecular basis of disease becomes realized through improved diagnostics and treatment, Molecular Pathology, Second Edition stands out as the most comprehensive textbook where molecular mechanisms represent the focus. It is uniquely concerned with the molecular basis of major human diseases and disease processes, presented in the context of traditional pathology, with implications for translational molecular medicine. The Second Edition of Molecular Pathology has been thoroughly updated to reflect seven years of exponential changes in the fields of genetics, molecular, and cell biology which molecular pathology translates in the practice of molecular medicine. The textbook is intended to serve as a multi-use textbook that would be appropriate as a classroom teaching tool for biomedical graduate students, medical students, allied health students, and others (such as advanced undergraduates). Further, this textbook will be valuable for pathology residents and other postdoctoral fellows that desire to advance their understanding of molecular mechanisms of disease beyond what they learned in medical/graduate school. In addition, this textbook is useful as a reference book for practicing basic scientists and physician scientists that perform disease-related basic science and translational research, who require a ready information resource on the molecular basis of various human diseases and disease states. Explores the principles and practice of molecular pathology: molecular pathogenesis, molecular mechanisms of disease, and how the molecular pathogenesis of disease parallels the evolution of the disease Explains the practice of “molecular medicine and the translational aspects of molecular pathology Teaches from the perspective of “integrative systems biology Enhanced digital version included with purchase

Molecular Diagnostics

Molecular Diagnostics
Author: William B. Coleman,Gregory J. Tsongalis
Publsiher: Springer Science & Business Media
Total Pages: 567
Release: 2006
ISBN 10: 1588293564
ISBN 13: 9781588293565
Language: EN, FR, DE, ES & NL

Molecular Diagnostics Book Review:

This updated and expanded tutorial guide to molecular diagnostic techniques takes advantage of many new molecular technologies to include both improved traditional methods and totally new methods, some not yet in routine use. The authors offer cutting-edge molecular diagnostics for genetic disease, human cancers, infectious diseases, and identity testing, as well as new insights into the question of quality assurance in the molecular diagnostics laboratory. Additional chapters address other technologies found in the clinical laboratory that complementary to molecular diagnostic technologies and discuss genetic counseling and the ethical and social issues involved with nucleic acid testing.

Principles of Molecular Medicine

Principles of Molecular Medicine
Author: Marschall S. Runge,Cam Patterson
Publsiher: Springer Science & Business Media
Total Pages: 1268
Release: 2007-11-18
ISBN 10: 159259963X
ISBN 13: 9781592599639
Language: EN, FR, DE, ES & NL

Principles of Molecular Medicine Book Review:

The concept of molecular medicine dates back to Linus means that there are many new opportunities and challenges Pauling, who in the late 1940s and early 1950s generalized for clinical medicine. One of the effects of the completion of from the ideas that came from the study of the sickle cell the Human Genome Project is the increasing application of hemoglobin molecule. With the first cloning of human genes the fields of molecular biology and genetics to the und- about 1976, molecular genetics took the molecular perspec- standing and management of common diseases. Assimi- tive on disease to the level of DNA. The term molecular tion of the new developments since the first edition has been medicine achieved wide currency in the 1980s with the ably accomplished by Drs. Runge and Patterson with the assignment of this designation to journals, at least one soci- help of their many knowledgeable authors. ety, institutes, and academic divisions of departments of in- As was evident in the first edition, molecular genetics is ternal medicine. Undoubtedly, molecular medicine has been involved in every specialty of medicine. A recurrent theme abetted by the Human Genome Project, which has aided in that edition, perhaps even more striking in the present one, greatly in the molecular characterization of disease.

Clinical Applications of PCR

Clinical Applications of PCR
Author: Y. M. Dennis Lo
Publsiher: Springer Science & Business Media
Total Pages: 353
Release: 1998
ISBN 10: 1592596002
ISBN 13: 9781592596003
Language: EN, FR, DE, ES & NL

Clinical Applications of PCR Book Review:

Clinical Applications of PCR offers an unprecedented collection of core PCR techniques for the study and diagnosis of human diseases. Cutting-edge and essential for today's diagnostic laboratories, these techniques heavily utilize nonisotopic, solution phase, and in situ amplification methods. A significant number of chapters describe applications exploiting the exquisite sensitivity of PCR in the detection of rare or single cells, as in identifying fetal cells circulating in maternal blood, preimplantation embryo diagnosis, or detecting circulating cancer cells. The methods described in Clinical Applications of PCR will well serve diverse clinical specialties ranging from hematology/oncology, human genetics, and microbiology, to virology, pathology, and infectious diseases. The book repeatedly demonstrates the power of PCR-its high sensitivity, specificity, and ability to rapidly discriminate sequence variations.

Advances in Molecular Pathology

Advances in Molecular Pathology
Author: Gregory J. Tsongalis
Publsiher: Elsevier
Total Pages: 329
Release: 2018-11-28
ISBN 10: 9780323639651
ISBN 13: 0323639658
Language: EN, FR, DE, ES & NL

Advances in Molecular Pathology Book Review:

This inaugural issue of Advances in Molecular Pathology will provide a comprehensive review of the most current practices, trends, and developments in the field of Molecular Pathology. Publishing on an annual basis, the volume will be divided into 7 sections: Genetics, Hematopathology, Infectious Disease, Pharmacogenomics, Informatics, Solid tumors, and Identity/HLA. Led by Dr. Gregory Tsongalis of Dartmouth University, a team of experienced pathologists from institutions across the country oversee annual topic and expert author selection. Topics discussed in this volume include, but are not limited to: whole genome sequencing in critically ill children, bioinformatics in clinical genomic sequencing, comprehensive monitoring of patients with chronic myeloid leukemia, genetic biomarkers in the biology and clinical workup of chronic lymphocytic leukemia, metagenomics in infectious disease, point of care molecular testing, pharmacogenomics in oncology, clinical uses of panel testing vs. single gene testing, large scale data sharing initiatives in genomic oncology, clinical NGS assays for solid tumors emerging concepts in liquid biopsy the cell line and tissue misidentification problem, and cell line detective work.

Diagnostic Molecular Pathology

Diagnostic Molecular Pathology
Author: William B. Coleman,Gregory J. Tsongalis
Publsiher: Academic Press
Total Pages: 582
Release: 2016-10-05
ISBN 10: 0128011572
ISBN 13: 9780128011577
Language: EN, FR, DE, ES & NL

Diagnostic Molecular Pathology Book Review:

Diagnostic Molecular Pathology: A Guide to Applied Molecular Testing is organized around disease types (genetic disease, infectious disease, neoplastic disease, among others). In each section, the authors provide background on disease mechanisms and describe how laboratory testing is built on knowledge of these mechanisms. Sections are dedicated to general methodologies employed in testing (to convey the concepts reflected in the methods), and specific description of how these methods can be applied and are applied to specific diseases are described. The book does not present molecular methods in isolation, but considers how other evidence (symptoms, radiology or other imaging, or other clinical tests) is used to guide the selection of molecular tests or how these other data are used in conjunction with molecular tests to make diagnoses (or otherwise contribute to clinical workup). In addition, final chapters look to the future (new technologies, new approaches) of applied molecular pathology and how discovery-based research will yield new and useful biomarkers and tests. Diagnostic Molecular Pathology: A Guide to Applied Molecular Testing contains exercises to test readers on their understanding of how molecular diagnostic tests are utilized and the value of the information that can be obtained in the context of the patient workup. Readers are directed to an ancillary website that contains supplementary materials in the form of exercises where decision trees can be employed to simulate actual clinical decisions. Focuses on the menu of molecular diagnostic tests available in modern molecular pathology or clinical laboratories that can be applied to disease detection, diagnosis, and classification in the clinical workup of a patient Explains how molecular tests are utilized to guide the treatment of patients in personalized medicine (guided therapies) and for prognostication of disease Features an ancillary website with self-testing exercises where decision trees can be employed to simulate actual clinical decisions Highlights new technologies and approaches of applied molecular pathology and how discovery-based research will yield new and useful biomarkers and tests

Essential Concepts in Molecular Pathology

Essential Concepts in Molecular Pathology
Author: William B. Coleman,Gregory J. Tsongalis
Publsiher: Academic Press
Total Pages: 462
Release: 2010-02-16
ISBN 10: 9780080922188
ISBN 13: 008092218X
Language: EN, FR, DE, ES & NL

Essential Concepts in Molecular Pathology Book Review:

This streamlined "essential" version of the Molecular Pathology (2009) textbook extracts key information, illustrations and photographs from the main textbook in the same number and organization of chapters. It is aimed at teaching students in courses where the full textbook is not needed, but the concepts included are desirable (such as graduate students in allied health programs or undergraduates). It is also aimed at students who are enrolled in courses that primarily use a traditional pathology textbook, but need the complementary concepts of molecular pathology (such as medical students). Further, the textbook will be valuable for pathology residents and other postdoctoral fellows who desire to advance their understanding of molecular mechanisms of disease beyond what they learned in medical/graduate school. Offers an essential introduction to molecular genetics and the "molecular" aspects of human disease Teaches from the perspective of "integrative systems biology," which encompasses the intersection of all molecular aspects of biology, as applied to understanding human disease In-depth presentation of the principles and practice of molecular pathology: molecular pathogenesis, molecular mechanisms of disease, and how the molecular pathogenesis of disease parallels the evolution of the disease using histopathology. "Traditional" pathology section provides state-of-the-art information on the major forms of disease, their pathologies, and the molecular mechanisms that drive these diseases. Explains the practice of "molecular medicine" and the translational aspects of molecular pathology: molecular diagnostics, molecular assessment, and personalized medicine Each chapter ends with Key Summary Points and Suggested Readings

Clinical Molecular Medicine

Clinical Molecular Medicine
Author: Dhavendra Kumar
Publsiher: Academic Press
Total Pages: 606
Release: 2019-11-30
ISBN 10: 0128094427
ISBN 13: 9780128094426
Language: EN, FR, DE, ES & NL

Clinical Molecular Medicine Book Review:

Clinical Molecular Medicine: Principles and Practice presents the latest scientific advances in molecular and cellular biology, including the development of new and effective drug and biological therapies and diagnostic methods. The book provides medical and biomedical students and researchers with a clear and clinically relevant understanding on the molecular basis of human disease. With an increased focus on new practice concepts, such as stratified, personalized and precision medicine, this book is a valuable and much-needed resource that unites the core principles of molecular biology with the latest and most promising genomic advances. Illustrates the fundamental principles and therapeutic applications of molecular and cellular biology Offers a clinically focused account of molecular heterogeneity Includes comprehensive coverage of many different disorders, including growth and development, cardiovascular, metabolic, skin, blood, digestive, inflammatory, neuropsychiatric disorders, and many more

An Introduction to Molecular Medicine and Gene Therapy

An Introduction to Molecular Medicine and Gene Therapy
Author: Thomas F. Kresina
Publsiher: John Wiley & Sons
Total Pages: 416
Release: 2004-04-07
ISBN 10: 0471461040
ISBN 13: 9780471461043
Language: EN, FR, DE, ES & NL

An Introduction to Molecular Medicine and Gene Therapy Book Review:

Gene therapy, or the use of genetic manipulation for diseasetreatment, is derived from advances in genetics, molecular biology,clinical medicine, and human genomics. Molecular medicine, theapplication of molecular biological techniques to disease treatmentand diagnosis, is derived from the development of human organtransplantation, pharmacotherapy, and elucidation of the humangenome. An Introduction to Molecular Medicine and GeneTherapy provides a basis for interpreting new clinical andbasic research findings in the areas of cloning, gene transfer, andtargeting; the applications of genetic medicine to clinicalconditions; ethics and governmental regulations; and the burgeoningfields of genomics, biotechnology, and bioinformatics. By dividingthe material into three sections - an introduction to basicscience, a review of clinical applications, and a discussion of theevolving issues related to gene therapy and molecular medicine-thiscomprehensive manual describes the basic approaches to the broadrange of actual and potential genetic-based therapies. In addition, An Introduction to Molecular Medicine andGene Therapy: Covers new frontiers in gene therapy, animal models, vectors,gene targeting, and ethical/legal considerations Provides organ-based reviews of current studies in gene therapyfor monogenetic, multifactoral or polygenic disorders, andinfectious diseases Includes bold-faced terms, key concepts, summaries, and listsof helpful references by subject in each chapter Contains appendices on commercial implications and a review ofthe history of gene therapy This textbook offers a clear, concise writing style, drawingupon the expertise of the authors, all renowned researchers intheir respective specialties of molecular medicine. Researchers ingenetics and molecular medicine will all find An Introductionto Molecular Medicine and Gene Therapy to be an essentialguide to the rapidly evolving field of gene therapy and itsapplications in molecular medicine.

Molecular Pathology in Clinical Practice

Molecular Pathology in Clinical Practice
Author: Debra G.B. Leonard
Publsiher: Springer
Total Pages: 1001
Release: 2016-02-02
ISBN 10: 331919674X
ISBN 13: 9783319196749
Language: EN, FR, DE, ES & NL

Molecular Pathology in Clinical Practice Book Review:

This authoritative textbook offers in-depth coverage of all aspects of molecular pathology practice and embodies the current standard in molecular testing. Since the successful first edition, new sections have been added on pharmacogenetics and genomics, while other sections have been revised and updated to reflect the rapid advances in the field. The result is a superb reference that encompasses molecular biology basics, genetics, inherited cancers, solid tumors, neoplastic hematopathology, infectious diseases, identity testing, HLA typing, laboratory management, genomics and proteomics. Throughout the text, emphasis is placed on the molecular variations being detected, the clinical usefulness of the tests and important clinical and laboratory issues. The second edition of Molecular Pathology in Clinical Practice will be an invaluable source of information for all practicing molecular pathologists and will also be of utility for other pathologists, clinical colleagues and trainees.