Channels Carriers and Pumps

Channels  Carriers  and Pumps
Author: Wilfred D. Stein,Thomas Litman
Publsiher: Academic Press
Total Pages: 406
Release: 2014-12-01
ISBN 10: 9780124165793
ISBN 13: 0124165796
Language: EN, FR, DE, ES & NL

Channels Carriers and Pumps Book Review:

An introduction to the principles of membrane transport: How molecules and ions move across the cell membrane by simple diffusion and by making use of specialized membrane components (channels, carriers, and pumps). The text emphasizes the quantitative aspects of such movement and its interpretation in terms of transport kinetics. Molecular studies of channels, carriers, and pumps are described in detail as well as structural principles and the fundamental similarities between the various transporters and their evolutionary interrelationships. The regulation of transporters and their role in health and disease are also considered. Provides an introduction to the properties of transport proteins: channels, carriers, and pumps Presents up-to-date information on the structure of transport proteins and on their function and regulation Includes introductions to transport kinetics and to the cloning of genes that code transport proteins Furnishes a link between the experimental basis of the subject and theoretical model building

Channels Carriers and Pumps

Channels  Carriers  and Pumps
Author: Wilfred D. Stein
Publsiher: Elsevier
Total Pages: 344
Release: 2012-12-02
ISBN 10: 0323138152
ISBN 13: 9780323138154
Language: EN, FR, DE, ES & NL

Channels Carriers and Pumps Book Review:

For students as well as researchers this book describes the exciting new advances in the molecular biology of transport proteins and integrates this information with transport kinetics, function, and regulation. Experimental data are linked with theory. Provides an introduction to the properties of transport proteins: channels, carriers, and pumps Presents up-to-date information on the structure of transport proteins and on their function and regulation Includes introductions to transport kinetics and to the cloning of genes that code transport proteins Furnishes a link between the experimental basis of the subject and theoretical model building

Molecular Biology of the Cell

Molecular Biology of the Cell
Author: Bruce Alberts
Publsiher: Unknown
Total Pages: 329
Release: 2004
ISBN 10: 9780815332183
ISBN 13: 0815332181
Language: EN, FR, DE, ES & NL

Molecular Biology of the Cell Book Review:

Pumps Channels and Transporters

Pumps  Channels and Transporters
Author: Ronald J. Clarke,Mohammed A. A. Khalid
Publsiher: John Wiley & Sons
Total Pages: 488
Release: 2015-09-16
ISBN 10: 1119085144
ISBN 13: 9781119085140
Language: EN, FR, DE, ES & NL

Pumps Channels and Transporters Book Review:

Describes experimental methods for investigating the function of pumps, channels and transporters Covers new emerging analytical methods used to study ion transport membrane proteins such as single-molecule spectroscopy Details a wide range of electrophysiological techniques and spectroscopic methods used to analyze the function of ion channels, ion pumps and transporters Covers state-of-the art analytical methods to study ion pumps, channels, and transporters, and where analytical chemistry can make further contributions

Transport And Diffusion Across Cell Membranes

Transport And Diffusion Across Cell Membranes
Author: Wilfred Stein
Publsiher: Elsevier
Total Pages: 704
Release: 2012-12-02
ISBN 10: 0323143202
ISBN 13: 9780323143202
Language: EN, FR, DE, ES & NL

Transport And Diffusion Across Cell Membranes Book Review:

Transport and Diffusion across Cell Membranes is a comprehensive treatment of the transport and diffusion of molecules and ions across cell membranes. This book shows that the same kinetic equations (with appropriate modification) can describe all the specialized membrane transport systems: the pores, the carriers, and the two classes of pumps. The kinetic formalism is developed step by step and the features that make a system effective in carrying out its biological role are highlighted. This book is organized into six chapters and begins with an introduction to the structure and dynamics of cell membranes, followed by a discussion on how the membrane acts as a barrier to the transmembrane diffusion of molecules and ions. The following chapters focus on the role of the membrane's protein components in facilitating transmembrane diffusion of specific molecules and ions, measurements of diffusion through pores and the kinetics of diffusion, and the structure of such pores and their biological regulation. This book methodically introduces the reader to the carriers of cell membranes, the kinetics of facilitated diffusion, and cotransport systems. The primary active transport systems are considered, emphasizing the pumping of an ion (sodium, potassium, calcium, or proton) against its electrochemical gradient during the coupled progress of a chemical reaction while a conformational change of the pump enzyme takes place. This book is of interest to advanced undergraduate students, as well as to graduate students and researchers in biochemistry, physiology, pharmacology, and biophysics.

Channels Carriers and Pumps

Channels  Carriers  and Pumps
Author: Wilfred D. Stein
Publsiher: Unknown
Total Pages: 326
Release: 1990
ISBN 10:
ISBN 13: UOM:39015068676082
Language: EN, FR, DE, ES & NL

Channels Carriers and Pumps Book Review:

For students as well as researchers this book describes the exciting new advances in the molecular biology of transport proteins and integrates this information with transport kinetics, function, and regulation. Experimental data are linked with theory. Key Features * Provides an introduction to the properties of transport proteins: channels, carriers, and pumps * Presents up-to-date information on the structure of transport proteins and on their function and regulation * Includes introductions to transport kinetics and to the cloning of genes that code transport proteins * Furnishes a link between the experimental basis of the subject and theoretical model building.

Ion Channels in Health and Sickness

Ion Channels in Health and Sickness
Author: Fatima Shad Kaneez
Publsiher: BoD – Books on Demand
Total Pages: 202
Release: 2018-10-10
ISBN 10: 1789842271
ISBN 13: 9781789842272
Language: EN, FR, DE, ES & NL

Ion Channels in Health and Sickness Book Review:

Ion channels are proteins that make pores in the membranes of excitable cells present both in the brain and the body. These cells are not only responsible for converting chemical and mechanical stimuli into the electrical signals but are also liable for monitoring vital functions. All our activities, from the blinking of our eyes to the beating of our heart and all our senses from smell to sight, touch, taste and hearing are regulated by the ion channels. This book will take us on an expedition describing the role of ion channels in congenital and acquired diseases and the challenges and limitations scientist are facing in the development of drugs targeting these membrane proteins.

Plant Nutrition

Plant Nutrition
Author: Walter Horst,M.K. Schenk,A. Bürkert,N. Claassen,H. Flessa,W.B. Frommer,Heiner E. Goldbach,H.-W. Olfs,V. Römheld,B. Sattelmacher,U. Schmidhalter,S. Schubert,N. von Wirén,L. Wittenmayer
Publsiher: Springer Science & Business Media
Total Pages: 1043
Release: 2006-05-18
ISBN 10: 030647624X
ISBN 13: 9780306476242
Language: EN, FR, DE, ES & NL

Plant Nutrition Book Review:

This volume is a compilation of extended abstracts of all papers presented at the 14th International Plant Nutrition Colloquium. Over 500 oral and poster presentations illustrate current knowledge and research emphasis in this subject, providing a comprehensive view of the state of plant nutrition research.

Introduction to Cellular Biophysics Volume 1

Introduction to Cellular Biophysics  Volume 1
Author: Armin Kargol
Publsiher: Morgan & Claypool Publishers
Total Pages: 116
Release: 2019-03-29
ISBN 10: 1643274104
ISBN 13: 9781643274102
Language: EN, FR, DE, ES & NL

Introduction to Cellular Biophysics Volume 1 Book Review:

All living matter is comprised of cells, small compartments isolated from the environment by a cell membrane and filled with concentrated solutions of various organic and inorganic compounds. Some organisms are single-cell, where all life functions are performed by that cell. Others have groups of cells, or entire organs, specializing in one particular function. The survival of the entire organism depends on all of its cells and organs fulfilling their roles. While the cells are studied by different sciences, they are seen differently by biologists, chemists, or physicists. Biologists concentrate their attention on cell structure and function. What does the cell consist of? Where are its organelles? What function does each organelle fulfil? From a chemists' point of view, a cell is a complex chemical reaction chamber where various molecules are synthesized or degraded. The main question is how these, sometimes very complicated chains of reactions are controlled. Finally, from a physics standpoint, one of the main questions is the physical movement of all these molecules between organelles within the cell, as well as their exchange with the extracellular medium. The aim of this book is to look into the basic physical phenomena occurring in cells. These physical transport processes facilitate chemical reactions in the cell and that in turn leads to the biological functions necessary for the cell to satisfy its role in the mother organism. Ultimately, the goals of every cell are to stay alive and to fulfil its function as a part of a larger organ or organism. This book is an inventory of physical transport processes occurring in cells while the second volume will be a closer look at how complex biological and physiological cell phenomena result from these very basic physical processes.

Red Cell Membrane Transport in Health and Disease

Red Cell Membrane Transport in Health and Disease
Author: Ingolf Bernhardt,J. Clive Ellory
Publsiher: Springer Science & Business Media
Total Pages: 748
Release: 2013-04-17
ISBN 10: 3662051818
ISBN 13: 9783662051818
Language: EN, FR, DE, ES & NL

Red Cell Membrane Transport in Health and Disease Book Review:

51 worldwide leading experts in the field of erythrocyte research contributed to this first book on transport processes in red blood cells. It explains the latest findings on the basis of well-established principles, in an accessibly structured and carefully organized compilation.

Anatomy and Physiology

Anatomy and Physiology
Author: J. Gordon Betts,Peter DeSaix,Jody E. Johnson,Oksana Korol,Dean H. Kruse,Brandon Poe,James A. Wise,Mark Womble,Kelly A. Young
Publsiher: Unknown
Total Pages: 329
Release: 2013-04-25
ISBN 10: 9781947172807
ISBN 13: 1947172808
Language: EN, FR, DE, ES & NL

Anatomy and Physiology Book Review:

Membrane Physiology

Membrane Physiology
Author: Thomas E. Andreoli,Darrell D. Fanestil,Joseph F. Hoffman,Stanley G. Schultz
Publsiher: Springer Science & Business Media
Total Pages: 384
Release: 2012-12-06
ISBN 10: 1461319439
ISBN 13: 9781461319436
Language: EN, FR, DE, ES & NL

Membrane Physiology Book Review:

Membrane Physiology (Second Edition) is a soft-cover book containing portions of Physiology of Membrane Disorders (Second Edition). The parent volume contains six major sections. This text encompasses the first three sections: The Nature of Biological Membranes, Methods for Studying Membranes, and General Problems in Membrane Biology. We hope that this smaller volume will be helpful to individuals interested in general physiology and the methods for studying general physiology. THOMAS E. ANDREOLI JOSEPH F. HOFFMAN DARRELL D. FANESTIL STANLEY G. SCHULTZ vii Preface to the Second Edition The second edition of Physiology of Membrane Disorders represents an extensive revision and a considerable expansion of the first edition. Yet the purpose of the second edition is identical to that of its predecessor, namely, to provide a rational analysis of membrane transport processes in individual membranes, cells, tissues, and organs, which in tum serves as a frame of reference for rationalizing disorders in which derangements of membrane transport processes playa cardinal role in the clinical expression of disease. As in the first edition, this book is divided into a number of individual, but closely related, sections. Part V represents a new section where the problem of transport across epithelia is treated in some detail. Finally, Part VI, which analyzes clinical derangements, has been enlarged appreciably.

Concepts of Biology

Concepts of Biology
Author: Samantha Fowler,Rebecca Roush,James Wise
Publsiher: Unknown
Total Pages: 618
Release: 2018-01-07
ISBN 10: 9789888407453
ISBN 13: 9888407457
Language: EN, FR, DE, ES & NL

Concepts of Biology Book Review:

Concepts of Biology is designed for the single-semester introduction to biology course for non-science majors, which for many students is their only college-level science course. As such, this course represents an important opportunity for students to develop the necessary knowledge, tools, and skills to make informed decisions as they continue with their lives. Rather than being mired down with facts and vocabulary, the typical non-science major student needs information presented in a way that is easy to read and understand. Even more importantly, the content should be meaningful. Students do much better when they understand why biology is relevant to their everyday lives. For these reasons, Concepts of Biology is grounded on an evolutionary basis and includes exciting features that highlight careers in the biological sciences and everyday applications of the concepts at hand.We also strive to show the interconnectedness of topics within this extremely broad discipline. In order to meet the needs of today's instructors and students, we maintain the overall organization and coverage found in most syllabi for this course. A strength of Concepts of Biology is that instructors can customize the book, adapting it to the approach that works best in their classroom. Concepts of Biology also includes an innovative art program that incorporates critical thinking and clicker questions to help students understand--and apply--key concepts.

Membrane Transporters and Channels as Targets for Drugs

Membrane Transporters and Channels as Targets for Drugs
Author: Graça Soveral,Cesare Indiveri
Publsiher: Frontiers Media SA
Total Pages: 329
Release: 2020-01-03
ISBN 10: 2889633578
ISBN 13: 9782889633579
Language: EN, FR, DE, ES & NL

Membrane Transporters and Channels as Targets for Drugs Book Review:

Transporters and channels are membrane proteins that mediate the traffic of metabolites, water and ions across biological membranes. Membrane transport proteins are crucial to maintain homeostasis and assure cell survival upon intracellular or environmental stress. A failure of any of these transport systems may have dramatic consequences for cell function. There is increasing evidence that membrane transport proteins play important functions in healthy conditions and that their absence or dysfunction may cause diseases. In recent years much attention has been paid to diseases resulting from defective transporters (“carrier diseases”) and ion channels (“channelopathies”). Very interestingly, altered expression of transporters has been described in several human pathologies. On this basis, many transport proteins are well acknowledged targets for drugs. Many others are involved in drug delivery and disposition and/or are considered potential targets. Others are off-targets for drugs and then, are responsible for side effects. Thus, membrane protein drug discovery is now an emerging field where the search for physiological mechanisms of regulation and for chemical compounds as modulators of transport activity, present new opportunities for drug development and for new therapies. This Research Topic addresses the latest research advances in membrane transport proteins, stimulating future research on these important protein families.

Exocytosis and Endocytosis

Exocytosis and Endocytosis
Author: Andrei I. Ivanov
Publsiher: Springer Science & Business Media
Total Pages: 412
Release: 2008
ISBN 10: 1588298655
ISBN 13: 9781588298652
Language: EN, FR, DE, ES & NL

Exocytosis and Endocytosis Book Review:

Due to their vital involvement in a wide variety of housekeeping and specialized cellular functions, exocytosis and endocytosis remain among the most popular subjects in biology and biomedical sciences. Tremendous progress in understanding these complex intracellular processes has been achieved by employing a wide array of research tools ranging from classical biochemical methods to modern imaging techniques. In Exocytosis and Endocytosis, skilled experts provide the most up-to-date,step-by-step laboratory protocols for examining molecular machinery and biological functions of exocytosis and endocytosis in vitro and in vivo. Following the highly successful Methods in Molecular BiologyTM series format, the chapters present an introduction outlining the principle behind each technique, a list of the necessary materials, an easy to follow, readily reproducible protocol, and a Notes section offering tips on troubleshooting and avoiding known pitfalls. Insightful to both newcomers and seasoned professionals, Exocytosis and Endocytosis offers a unique and highly practical guide to versatile laboratory tools developed to study various aspects of intracellular vesicle trafficking in simple model systems and living organisms.

Transport Through Membranes

Transport Through Membranes
Author: Alberte Pullman,Bernard Pullman,Joshua Jortner
Publsiher: Unknown
Total Pages: 570
Release: 1988
ISBN 10:
ISBN 13: OCLC:640142880
Language: EN, FR, DE, ES & NL

Transport Through Membranes Book Review:

Transport Through Membranes Carriers Channels and Pumps

Transport Through Membranes  Carriers  Channels and Pumps
Author: A. Pullman,Joshua Jortner
Publsiher: Springer Science & Business Media
Total Pages: 570
Release: 2012-12-06
ISBN 10: 9400930755
ISBN 13: 9789400930759
Language: EN, FR, DE, ES & NL

Transport Through Membranes Carriers Channels and Pumps Book Review:

The Symposium on "Transport through Membranes : Carriers. Channels and Pumps" Inaugurates the third decade of the Jerusalem Symposia. It enlarges substantially their conceptual scope by Introducing a new subject not treated there previously. In fact. It Is a topic particularly well suited for the general object of these International meetings which Is to reassemble In an exhaustive Interdisciplinary discussion chemists. physicists and biologists. theoreticians and experimentalists. The main theme of the Symposium was the presentation and evaluation of the most up-to-date data on the structural and dynamic aspects of transport through membranes within the three main pathways: through carriers. channels and pumps. This goal was fully achieved thanks to the participation of a most outstanding assembly of world's experts In the field. We wish to thank Madame Pullman. the real organizer and mainspring of this meeting. for having composed a most exciting and excellent program and for carrying It out successfully. As the twenty preceding ones this Symposium was held under the auspices of the Israel Academy of Sciences and Humanities and the Hebrew University of Jerusalem. It was sponsored by the Instltut de Blologle Physlco Chimique. Fondatlon Edmond de Rothschild of Paris. We wish to express once again our gratitude to the Baron Edmond de Rothschild for his constant and generous support which makes this continuous endeavour possible.

Transporters as Drug Targets

Transporters as Drug Targets
Author: Gerhard F. Ecker,Rasmus P. Clausen,Gerd Folkers,Harald H. Sitte,Raimund Mannhold,Helmut Buschmann
Publsiher: John Wiley & Sons
Total Pages: 354
Release: 2017-04-10
ISBN 10: 3527333843
ISBN 13: 9783527333844
Language: EN, FR, DE, ES & NL

Transporters as Drug Targets Book Review:

As opposed to other books on the topic, this volume is unique in also covering emerging transporter targets. Following a general introduction to the importance of targeting transporter proteins with drugs, the book systematically presents individual transporter classes and explains their pharmacology and physiology. The text covers all transporter families with known or suspected importance as drug targets, including neurotransmitter transporters, ABC transporters, glucose transporters and organic ion transporters. The final part discusses recent advances in structural studies of transport proteins, assay methods for transport activity, and the systems biology of transporters and their regulation. With its focus on drug development issues, this authoritative overview is required reading for researchers in industry and academia targeting transport proteins for the treatment of disease.

Fractal Physiology

Fractal Physiology
Author: James B Bassingthwaighte,Larry S Liebovitch,Bruce J West
Publsiher: Springer
Total Pages: 384
Release: 2013-05-27
ISBN 10: 1461475724
ISBN 13: 9781461475729
Language: EN, FR, DE, ES & NL

Fractal Physiology Book Review:

I know that most men, including those at ease with the problems of the greatest complexity, can seldom accept even the simplest and most obvious truth if it be such as would oblige them to admit the falsity of conclusions which they have delighted in explaining to colleagues, which they have proudly taught to others, and which they have woven, thread by thread, into the fabric of their lives. Joseph Ford quoting Tolstoy (Gleick, 1987) We are used to thinking that natural objects have a certain form and that this form is determined by a characteristic scale. If we magnify the object beyond this scale, no new features are revealed. To correctly measure the properties of the object, such as length, area, or volume, we measure it at a resolution finer than the characteristic scale of the object. We expect that the value we measure has a unique value for the object. This simple idea is the basis of the calculus, Euclidean geometry, and the theory of measurement. However, Mandelbrot (1977, 1983) brought to the world's attention that many natural objects simply do not have this preconceived form. Many of the structures in space and processes in time of living things have a very different form. Living things have structures in space and fluctuations in time that cannot be characterized by one spatial or temporal scale. They extend over many spatial or temporal scales.

Ionic Channels of Excitable Membranes

Ionic Channels of Excitable Membranes
Author: Bertil Hille
Publsiher: Sinauer Associates, Incorporated
Total Pages: 607
Release: 1992
ISBN 10:
ISBN 13: UOM:39015024124383
Language: EN, FR, DE, ES & NL

Ionic Channels of Excitable Membranes Book Review:

This new, fully revised and expanded edition of Ionic Channels of Excitable Membranes includes new chapters on fast chemical synapses, modulation through G protein coupled receptors and second messenger systems, molecules cloning, site directed mutagenesis, and cell biology. It begins with the classical biophysical work of Hodgkin and Huxley and then weaves a description of the known ionic channels together with their biological functions. The book continues by developing the physical and molecular principles needed for explaining permeation, gating, pharmacological modification, and molecular diversity, and ends with a discussion of channel evolution. Ionic Channels of Excitable Membranes is written to be accessible and interesting to biological and physical scientists of all kinds.