Cellular Response to Biomaterials

Cellular Response to Biomaterials
Author: Lucy Di Silvio
Publsiher: Elsevier
Total Pages: 648
Release: 2008-12-22
ISBN 10: 184569547X
ISBN 13: 9781845695477
Language: EN, FR, DE, ES & NL

Cellular Response to Biomaterials Book Review:

The response of cells to biomaterials is critical in medical devices. Traditionally inert biomaterials were used to minimise the reaction in cells in contact with the material. However, it has been realised that specific cell responses may be beneficial in such areas as encouraging adhesion, healing or cell multiplication. Cellular response to biomaterials discusses the response of cells to a wide range of biomaterials targeted at specific medical applications. Part one discusses cell responses to a variety of polymers and ceramics with chapters on such topics as degradable polymers and biocompatibility. Part two covers cell responses and regenerative medicine with coverage of themes such as vascular grafts, nerve repair and Bioglass®. Part three examines the effect of surfaces and proteins on cell response. Specific chapters review nano-engineered surfaces, the influence of plasma proteins on bone cell adhesion and surface modification of titanium implants. With its distinguished editor and team of international contributors, Cellular response to biomaterials is an essential read for those researching or studying medical devices in industry and academia. Examines the response of cells to a wide range of biomaterials targeted at specific medical applications Discusses cell responses and regenerative medicine with specific chapters on vascular grafts and nerve repair Assesses the effect of surfaces and proteins on cell response including the influence of plasma proteins on cell adhesion and surface modification of titanium implants

Biomaterials and Immune Response

Biomaterials and Immune Response
Author: Nihal Engin Vrana
Publsiher: CRC Press
Total Pages: 249
Release: 2018-07-20
ISBN 10: 1351377558
ISBN 13: 9781351377553
Language: EN, FR, DE, ES & NL

Biomaterials and Immune Response Book Review:

The interactions of the biomaterials with the host immune system is crucial for their functionality. This book aims to provide the reader with a better understanding of the role of the immune system in biomaterial applications. For this end, the book has dedicated chapters for i) explaining immune cells taking part in immune response to biomaterials/immune systems interface; ii) the effect of biomaterial shape, form and physicochemical properties on the response of immune system; iii) biofilm formation on implanted materials as a failure of immune system/biomaterial interactions; iv) tissue-specific effects of immune response and its consequences for tissue engineering and regenerative medicine; v) immune reaction in a clinical context (periodontology). In the field of biomaterials there are significant advances in using immunomodulation techniques to improve the success rates of implantable materials. For better understanding of such techniques it is required to have a full grasp of the biomaterial–immune system interactions. This would greatly enhance the understanding of why the human body reacts to implants in a certain way and how to improve the clinical outcomes by developing immune-instructive biomaterials. Provides keen insight into biomaterial–immune cell interactions Presents an explanation of state-of-the-art methodologies in immunomodulation Offers a concise and simple-to-understand treatment of biomaterial–immune cell interactions for materials scientists in a biology heavy topic Explores a comprehensive overview of biomaterial related complications Provides extensive references at the end of each chapter to enhance study for this very hot research area

Monitoring Cellular Response to Biomaterials

Monitoring Cellular Response to Biomaterials
Author: Ryan S. Czarny
Publsiher: Unknown
Total Pages: 40
Release: 2016
ISBN 10: 1928374650XXX
ISBN 13: OCLC:951979941
Language: EN, FR, DE, ES & NL

Monitoring Cellular Response to Biomaterials Book Review:

Host Response to Biomaterials

Host Response to Biomaterials
Author: Stephen F Badylak
Publsiher: Academic Press
Total Pages: 460
Release: 2015-05-08
ISBN 10: 0128005009
ISBN 13: 9780128005002
Language: EN, FR, DE, ES & NL

Host Response to Biomaterials Book Review:

Host Response to Biomaterials: The Impact of Host Response on Biomaterial Selection explains the various categories of biomaterials and their significance for clinical applications, focusing on the host response to each biomaterial. It is one of the first books to connect immunology and biomaterials with regard to host response. The text also explores the role of the immune system in host response, and covers the regulatory environment for biomaterials, along with the benefits of synthetic versus natural biomaterials, and the transition from simple to complex biomaterial solutions. Fields covered include, but are not limited to, orthopaedic surgery, dentistry, general surgery, neurosurgery, urology, and regenerative medicine. Explains the various categories of biomaterials and their significance for clinical applications Contains a range of extensive coverage, including, but not limited to, orthopedic, surgery, dental, general surgery, neurosurgery, lower urinary tract, and regenerative medicine Includes regulations regarding combination devices

Immunomodulatory Biomaterials

Immunomodulatory Biomaterials
Author: Stephen F. Badylak,Jennifer Elisseeff
Publsiher: Woodhead Publishing
Total Pages: 294
Release: 2021-07-30
ISBN 10: 0128214562
ISBN 13: 9780128214565
Language: EN, FR, DE, ES & NL

Immunomodulatory Biomaterials Book Review:

Biomaterials have existed for millennia as mechanical replacement structures following disease or injury. Biomaterial design has changed markedly from structural support with an “inert immune profile as the primary objective to designs that elicit an integrative local tissue response and a pro-repair immune cell phenotype. Immunomodulatory Biomaterials: Regulating the Immune Response with Biomaterials to Affect Clinical Outcome offers a single, comprehensive reference on biomaterials for modulation of the host response, for materials scientists, tissue engineers and those working in regenerative medicine. This book details methods, materials and strategies designed to regulate the host immune response following surgical implantation and thus facilitate specific local cell infiltration and tissue deposition. There has been a dramatic transformation in our understanding of the role of the immune system, both innate and adaptive; these changes include recognition of the plasticity of immune cells, especially macrophages, cross-talk between the immune system and stem cells, and the necessity for in situ transition between inflammatory and regulatory immune cell phenotypes. The exploitation of these findings and the design and manufacture of new biomaterials is occurring at an astounding pace. There is currently no book directed at the interdisciplinary principles guiding the design, manufacture, testing, and clinical translation of biomaterials that proactively regulate the host tissue immune response. The challenge for academia, industry, and regulatory agencies to encourage innovation while assuring safety and maximizing efficacy has never been greater. Given the highly interdisciplinary requirements for the design, manufacture and use of immunomodulatory biomaterials, this book will prove a useful single resource across disciplines. Holistically covers the design, manufacture, testing, and clinical translation of biomaterials that proactively regulate the host tissue immune response Provides a single reference for understanding and utilizing the host response in biomaterials design An international collaboration of leading researchers in the field offering a novel insight into this fast-growing area

The Immune Response to Implanted Materials and Devices

The Immune Response to Implanted Materials and Devices
Author: Bruna Corradetti
Publsiher: Springer
Total Pages: 241
Release: 2016-11-30
ISBN 10: 3319454331
ISBN 13: 9783319454337
Language: EN, FR, DE, ES & NL

The Immune Response to Implanted Materials and Devices Book Review:

This book provides a comprehensive overview of the cascade of events activated in the body following the implant of biomaterials and devices. It is one of the first books to shed light on the role of the host immune response on therapeutic efficacy, and reviews the state-of-the-art for both basic science and medical applications. The text examines advantages and disadvantages of the use of synthetic versus natural biomaterials. Particular emphasis is placed on the role of biomimicry in the development of smart strategies able to modulate infiltrating immune cells, thus reducing side effects (such as acute and chronic inflammation, fibrosis and/or implant rejection) and improving the therapeutic outcome (healing, tissue restoration). Current cutting-edge approaches in tissue engineering, regenerative medicine, and nanomedicine offer the latest insights into the role immunomodulation in improving tolerance during tissue transplant in the treatment of orthopaedic, pancreatic, and hepatic diseases. "Immune Response to Implanted Materials and Devices" is intended for an audience of graduate students and professional researchers in both academia and industry interested in the development of smart strategies, which are able to exploit the self-healing properties of the body and achieve functional tissue restoration.

Regenerative Medicine Applications in Organ Transplantation

Regenerative Medicine Applications in Organ Transplantation
Author: Giuseppe Orlando
Publsiher: Academic Press
Total Pages: 1050
Release: 2013-10-11
ISBN 10: 012398520X
ISBN 13: 9780123985200
Language: EN, FR, DE, ES & NL

Regenerative Medicine Applications in Organ Transplantation Book Review:

Regenerative Medicine Applications in Organ Transplantation illustrates exactly how these two fields are coming together and can benefit one another. It discusses technologies being developed, methods being implemented, and which of these are the most promising. The text encompasses tissue engineering, biomaterial sciences, stem cell biology, and developmental biology, all from a transplant perspective. Organ systems considered include liver, renal, intestinal, pancreatic, and more. Leaders from both fields have contributed chapters, clearly illustrating that regenerative medicine and solid organ transplantation speak the same language and that both aim for similar medical outcomes. The overall theme of the book is to provide insight into the synergy between organ transplantation and regenerative medicine. Recent groundbreaking achievements in regenerative medicine have received unprecedented coverage by the media, fueling interest and enthusiasm in transplant clinicians and researchers. Regenerative medicine is changing the premise of solid organ transplantation, requiring transplantation investigators to become familiar with regenerative medicine investigations that can be extremely relevant to their work. Similarly, regenerative medicine investigators need to be aware of the needs of the transplant field to bring these two fields together for greater results. Bridges the gap between regenerative medicine and solid organ transplantation and highlights reasons for collaboration Explains the importance and future potential of regenerative medicine to the transplant community Illustrates to regenerative medicine investigators the needs of the transplant discipline to drive and guide investigations in the most promising directions

Control of Cellular Response by Laser Interference ablated Biomaterials

Control of Cellular Response by Laser Interference ablated Biomaterials
Author: Ping Li
Publsiher: Unknown
Total Pages: 135
Release: 2005
ISBN 10: 1928374650XXX
ISBN 13: OCLC:255316498
Language: EN, FR, DE, ES & NL

Control of Cellular Response by Laser Interference ablated Biomaterials Book Review:

Oxidative Stress and Biomaterials

Oxidative Stress and Biomaterials
Author: Thomas Dziubla,D Allan Butterfield
Publsiher: Academic Press
Total Pages: 404
Release: 2016-05-31
ISBN 10: 0128032707
ISBN 13: 9780128032701
Language: EN, FR, DE, ES & NL

Oxidative Stress and Biomaterials Book Review:

Oxidative Stress and Biomaterials provides readers with the latest information on biomaterials and the oxidative stress that can pose an especially troubling challenge to their biocompatibility, especially given the fact that, at the cellular level, the tissue environment is a harsh landscape of precipitating proteins, infiltrating leukocytes, released oxidants, and fluctuations of pH which, even with the slightest shift in stasis, can induce a perpetual state of chronic inflammation. No material is 100% non-inflammatory, non-toxic, non-teratogenic, non-carcinogenic, non-thrombogenic, and non-immunogenic in all biological settings and situations. In this embattled terrain, the most we can hope for from the biomaterials we design is a type of “meso-compatibility, a material which can remain functional and benign for as long as required without succumbing to this cellular onslaught and inducing a local inflammatory reaction. Explores the challenges of designing and using biomaterials in order to minimize oxidative stress, reducing patterns of chronic inflammation and cell death Brings together the two fields of biomaterials and the biology of oxidative stress Provides approaches for the design of biomaterials with improved biocompatibility

Peptides and Proteins as Biomaterials for Tissue Regeneration and Repair

Peptides and Proteins as Biomaterials for Tissue Regeneration and Repair
Author: Mario Barbosa,M Cristina L Martins
Publsiher: Woodhead Publishing
Total Pages: 390
Release: 2017-09-25
ISBN 10: 008100852X
ISBN 13: 9780081008522
Language: EN, FR, DE, ES & NL

Peptides and Proteins as Biomaterials for Tissue Regeneration and Repair Book Review:

Peptides and Proteins as Biomaterials for Tissue Regeneration and Repair highlights the various important considerations that go into biomaterial development, both in terms of fundamentals and applications. After covering a general introduction to protein and cell interactions with biomaterials, the book discusses proteins in biomaterials that mimic the extracellular matrix (ECM). The properties, fabrication and application of peptide biomaterials and protein-based biomaterials are discussed in addition to in vivo and in vitro studies. This book is a valuable resource for researchers, scientists and advanced students interested in biomaterials science, chemistry, molecular biology and nanotechnology. Presents an all-inclusive and authoritative coverage of the important role which protein and peptides play as biomaterials for tissue regeneration Explores protein and peptides from the fundamentals, to processing and applications Written by an international group of leading biomaterials researchers

Characterization of Biomaterials

Characterization of Biomaterials
Author: Y.M. Thasneem,Chandra P. Sharma
Publsiher: Elsevier Inc. Chapters
Total Pages: 450
Release: 2013-03-12
ISBN 10: 0128070994
ISBN 13: 9780128070994
Language: EN, FR, DE, ES & NL

Characterization of Biomaterials Book Review:

The development of biomaterials as a powerful regulator of the cellular microenvironment for application in drug discovery/delivery, tissue engineering, and implant biology, requires a better understanding of cell-surface interactions at macro, micro, and nanometre levels. Cell–substrate interactions are multifaceted, involving the integration of various physical and biochemical signals. The interactions among these micro-environmental factors cannot be facilely elucidated and quantified by conventional experimentations, and this necessitates multifactorial strategies. A major task in the biomaterials field would be to develop advanced tools that can offer greater insight into characterizing the cellular behavior and interactions on the material interface. Obtaining this information is crucial in taking biomaterial science to new realms for biomedical applications. The contribution of molecular techniques to elucidate the cell–biomaterial interactions is indispensable on the time-course and level of expression of particular genes that determine cellular phenotype. The amalgamation of multiple disciplines has already produced many interesting techniques and approaches for the cell–biomaterial characterization, of which we have tried to provide a comprehensive and integrated description. The main focus of this book chapter is to explore the toolbox contents available in elucidating the cell–biomaterial interactions. We brief about the topographical, mechanical and biochemical changes faced by a cell upon the rendezvous of any surface in particular with the cell–biomaterial interface. The material characteristics playing cards in directing cellular behavior are straightened out. We also discuss the current knowledge of how a cell can interact with a substrate at the nanoscale and the effect of size, morphology, organization and separation of nanofeatures on cell response.

Microstructure Cellular Response and Selected Properties of Titanium Based Biomaterials Applied in Regenerative Medicine of Bone Tissue and Joints

Microstructure  Cellular Response and Selected Properties of Titanium Based Biomaterials Applied in Regenerative Medicine of Bone Tissue and Joints
Author: Joanna Karbowniczek
Publsiher: Unknown
Total Pages: 135
Release: 2019
ISBN 10: 1928374650XXX
ISBN 13: OCLC:1135426269
Language: EN, FR, DE, ES & NL

Microstructure Cellular Response and Selected Properties of Titanium Based Biomaterials Applied in Regenerative Medicine of Bone Tissue and Joints Book Review:

Handbook of Biomaterials Biocompatibility

Handbook of Biomaterials Biocompatibility
Author: Masoud Mozafari
Publsiher: Woodhead Publishing Limited
Total Pages: 625
Release: 2020-06
ISBN 10: 9780081029671
ISBN 13: 0081029675
Language: EN, FR, DE, ES & NL

Handbook of Biomaterials Biocompatibility Book Review:

Handbook of Biomaterials Biocompatibility is a systematic reference on host response to different biomaterials, taking into account their physical, mechanical and chemical properties. The book reviews recent progress in the design and study of biomaterials biocompatibility, along with current understanding on how to control immune system response. Sections provide the fundamental theories and challenges of biomaterials biocompatibility, the role of different biomaterials physicochemical surface properties on cell responses, cell responses to different physicochemical properties of polymers, ceramics, metals, carbons and nanomaterials, and biomaterials in different tissues, such as the cardiac, nervous system, cartilage and bone. This resource will be suitable for those working in the fields of materials science, regenerative engineering, medicine, medical devices and nanotechnology. Reviews the fundamental theories and challenges of biomaterials biocompatibility, including an overview of the standards and regulations Provides an overview on the cellular and molecular mechanisms involved in host responses to biomaterials Systematically looks at cellular response and tissue response to a wide range of biomaterials, including polymers, metals, ceramics, alloys and nanomaterials

Surface Modification of Biomaterials

Surface Modification of Biomaterials
Author: Rachel Williams
Publsiher: Elsevier
Total Pages: 432
Release: 2010-11-25
ISBN 10: 0857090763
ISBN 13: 9780857090768
Language: EN, FR, DE, ES & NL

Surface Modification of Biomaterials Book Review:

The surface modification of biomaterials plays a significant role in determining the outcome of biological-material interactions. With the appropriate modification a material’s surface can be tailored to improve biocompatibility, adhesion and cell interactions. Consequently surface modification is vital in the development and design of new biomaterials and medical devices. Surface modification of biomaterials reviews both established surface modifications and those still in the early stages of research and discusses how they can be used to optimise biological interactions and enhance clinical performance. Part one begins with chapters looking at various types and techniques of surface modification including plasma polymerisation, covalent binding of poly (ethylene glycol) (PEG), heparinisation, peptide functionalisation and calcium phosphate deposition before going on to examine metal surface oxidation and biomaterial surface topography to control cellular response with particular reference to technologies, cell behaviour and biomedical applications. Part two studies the analytical techniques and applications of surface modification with chapters on analysing biomaterial surface chemistry, surface structure, morphology and topography before moving onto discuss modifying biomaterial surfaces to optimise interactions with blood, control infection, optimise interactions with soft tissues, repair and regenerate nerve cells, control stem cell growth and differentiation and to optimise interactions with bone. The distinguished editor and international team of contributors to Surface modification of biomaterials have produced a unique overview and detailed chapters on a range of surface modification techniques which will provide an excellent resource for biomaterials researchers and scientists and engineers concerned with improving the properties of biomaterials. It will also be beneficial for academics researching surface modification. Reviews both established surface modifications and those still in the early stages of research and how they can be used to optimise biological interactions and enhance clinical performance Studies analytical techniques and applications of surface modification with chapters assessing biomaterial surface chemistry, surface structure, morphology and topography Discusses modifying biomaterial surfaces to optimise interactions with blood and soft tissues and also to repair and regenerate nerve cells and control infection

Biologically responsive Hybrid Biomaterials

Biologically responsive Hybrid Biomaterials
Author: Esmaiel Jabbari,Ali Khademhosseini
Publsiher: World Scientific
Total Pages: 423
Release: 2010
ISBN 10: 981429568X
ISBN 13: 9789814295680
Language: EN, FR, DE, ES & NL

Biologically responsive Hybrid Biomaterials Book Review:

Conjugation of synthetic materials with cell-responsive biologically-active molecules, in addition to providing structural support and release of biomolecules in the regenerating region, can provide the signaling factors required to initiate the cascade of cell migration, adhesion, differentiation, maturation, growth factor modulation, maintenance of matrix integrity, and tissue morphogenesis. Nanoparticles conjugated with ligands that preferentially interact with cell surface receptors in the tumor environment have the potential to drastically improve bioavailability, selectivity and residence time of the chemotherapeutic agent in the tumor microenvironment, while limiting their peripheral toxicity. Multivalent presentation of tumor-associated antigens on a targeted delivery system containing T and B cell epitopes can result in strong, long-lasting, self-adjuvant immunity against cancer and other diseases in vaccination. These examples demonstrate that cell-responsive conjugate biomaterials have profoundly impacted the medical field. This book is divided into three sections. In the first section, synthesis and characterization, conformation, structure-activity, self-assembly, and host response of conjugate hybrid biomaterials are covered. The second section is dedicated to the applications of conjugate biomaterials in drug delivery and vaccination while the last section is devoted to tissue engineering applications including cell adhesion, control of the stem cell niche, cartilage regeneration, neural and vascular tissue engineering, and dynamic cell culture systems for functionalized biomaterials. There is no doubt that biologically-responsive conjugate biomaterials play a key role in the design of biologics and medical devices, and this pioneering reference book provides a comprehensive review on synthesis, characterization, structure-activity, 3D assembly/fabrication, host response and the emerging applications of conjugate hybrid biomaterials.

Bio Implant Interface

Bio Implant Interface
Author: J.E. Ellingsen,S.P. Lyngstadaas
Publsiher: CRC Press
Total Pages: 464
Release: 2003-04-29
ISBN 10: 1135508216
ISBN 13: 9781135508210
Language: EN, FR, DE, ES & NL

Bio Implant Interface Book Review:

Achieving good clinical outcomes with implanted biomaterials depends upon achieving optimal function, both mechanical and biological, which in turn depends upon integrating advances realized in biological science, material science, and tissue engineering. As these advances push back the frontiers of biomaterial medicine , the control and patterning

Biomaterials

Biomaterials
Author: Anonim
Publsiher: Unknown
Total Pages: 125
Release: 1994
ISBN 10: 1928374650XXX
ISBN 13: UCSD:31822037140688
Language: EN, FR, DE, ES & NL

Biomaterials Book Review:

Wound Closure Biomaterials and Devices

Wound Closure Biomaterials and Devices
Author: Chih-Chang Chu,J. Anthony von Fraunhofer,Howard P. Greisler
Publsiher: CRC Press
Total Pages: 416
Release: 2018-05-04
ISBN 10: 1351404008
ISBN 13: 9781351404006
Language: EN, FR, DE, ES & NL

Wound Closure Biomaterials and Devices Book Review:

"Virtually every wound, whether surgical or traumatic, needs to be closed to promote wound healing and prevent infection. Increasingly sophisticated and effective materials for the crucial surgical treatment of wound closure are being developed continuously. Keep up with the most recent research progress and future trends in this complex and rapidly changing field with Wound Closure Biomaterial and Devices. This state-of-the-art book provides detailed information and critical discussions on: ï

Bone Augmentation by Anatomical Region

Bone Augmentation by Anatomical Region
Author: Zvi Artzi
Publsiher: John Wiley & Sons
Total Pages: 560
Release: 2020-05-15
ISBN 10: 1119427908
ISBN 13: 9781119427902
Language: EN, FR, DE, ES & NL

Bone Augmentation by Anatomical Region Book Review:

Comprehensively describes bone augmentation techniques and their application to the different anatomical regions of the upper and lower jaws. Bone Augmentation by Anatomical Region is a unique, evidence-based guide focusing on each specific anatomical region – anterior maxilla, posterior maxilla, anterior mandible, and posterior mandible – in order to emphasize the correct implemented procedures needed to successfully perform oral osseous reconstruction. Numerous ridge augmentation techniques are covered, including: horizontal and vertical guided bone regeneration, autologous block transplantation, interpositional bone grafting, allogeneic blocks, sandwich technique, split-expansion ridge technique, and sinus floor grafting. Non-augmented approaches such as forced socket site extrusion and the installation of digitally printed implants are also presented and discussed. Guides readers on tackling bone augmentation via anatomical region of the jaws and their related surrounding muscles, vascularization and innervation Presents innovative augmentation techniques for the anterior maxilla, posterior maxilla, anterior mandible, and posterior mandible Includes clinical photographs in each section and a decision tree to help readers select the appropriate surgical modality Bone Augmentation by Anatomical Region is a specialist resource suitable for dentists who practice implant dentistry, oral surgeons, oral and maxillofacial surgeons, periodontists, and postgraduate dental students in the above-mentioned disciplines. Please note Due to recently developments, part of Chapter 2 Biologic Conditions for Bone Growth and Maintenance: Managing the Oxidative Stress has been amended which will be available in all future reprints. All electronic versions have been updated.

Biomimetics

Biomimetics
Author: Amitava Mukherjee
Publsiher: BoD – Books on Demand
Total Pages: 544
Release: 2010-03-01
ISBN 10: 9533070250
ISBN 13: 9789533070254
Language: EN, FR, DE, ES & NL

Biomimetics Book Review:

Nature’s evolution has led to the introduction of highly efficient biological mechanisms. Imitating these mechanisms offers an enormous potential for the improvement of our day to day life. Ideally, by bio-inspiration we can get a better view of nature’s capability while studying its models and adapting it for our benefit. This book takes us into the interesting world of biomimetics and describes various arenas where the technology is applied. The 25 chapters covered in this book disclose recent advances and new ideas in promoting the mechanism and applications of biomimetics.