Cellular Response to Biomaterials

Cellular Response to Biomaterials
Author: Lucy Di Silvio
Publsiher: Elsevier
Total Pages: 648
Release: 2008-12-22
ISBN 10: 184569547X
ISBN 13: 9781845695477
Language: EN, FR, DE, ES & NL

Cellular Response to Biomaterials Book Review:

The response of cells to biomaterials is critical in medical devices. Traditionally inert biomaterials were used to minimise the reaction in cells in contact with the material. However, it has been realised that specific cell responses may be beneficial in such areas as encouraging adhesion, healing or cell multiplication. Cellular response to biomaterials discusses the response of cells to a wide range of biomaterials targeted at specific medical applications. Part one discusses cell responses to a variety of polymers and ceramics with chapters on such topics as degradable polymers and biocompatibility. Part two covers cell responses and regenerative medicine with coverage of themes such as vascular grafts, nerve repair and Bioglass®. Part three examines the effect of surfaces and proteins on cell response. Specific chapters review nano-engineered surfaces, the influence of plasma proteins on bone cell adhesion and surface modification of titanium implants. With its distinguished editor and team of international contributors, Cellular response to biomaterials is an essential read for those researching or studying medical devices in industry and academia. Examines the response of cells to a wide range of biomaterials targeted at specific medical applications Discusses cell responses and regenerative medicine with specific chapters on vascular grafts and nerve repair Assesses the effect of surfaces and proteins on cell response including the influence of plasma proteins on cell adhesion and surface modification of titanium implants

Biomaterials and Immune Response

Biomaterials and Immune Response
Author: Nihal Engin Vrana
Publsiher: CRC Press
Total Pages: 249
Release: 2018-07-20
ISBN 10: 1351377558
ISBN 13: 9781351377553
Language: EN, FR, DE, ES & NL

Biomaterials and Immune Response Book Review:

The interactions of the biomaterials with the host immune system is crucial for their functionality. This book aims to provide the reader with a better understanding of the role of the immune system in biomaterial applications. For this end, the book has dedicated chapters for i) explaining immune cells taking part in immune response to biomaterials/immune systems interface; ii) the effect of biomaterial shape, form and physicochemical properties on the response of immune system; iii) biofilm formation on implanted materials as a failure of immune system/biomaterial interactions; iv) tissue-specific effects of immune response and its consequences for tissue engineering and regenerative medicine; v) immune reaction in a clinical context (periodontology). In the field of biomaterials there are significant advances in using immunomodulation techniques to improve the success rates of implantable materials. For better understanding of such techniques it is required to have a full grasp of the biomaterial–immune system interactions. This would greatly enhance the understanding of why the human body reacts to implants in a certain way and how to improve the clinical outcomes by developing immune-instructive biomaterials. Provides keen insight into biomaterial–immune cell interactions Presents an explanation of state-of-the-art methodologies in immunomodulation Offers a concise and simple-to-understand treatment of biomaterial–immune cell interactions for materials scientists in a biology heavy topic Explores a comprehensive overview of biomaterial related complications Provides extensive references at the end of each chapter to enhance study for this very hot research area

Host Response to Biomaterials

Host Response to Biomaterials
Author: Stephen F Badylak
Publsiher: Academic Press
Total Pages: 460
Release: 2015-05-08
ISBN 10: 0128005009
ISBN 13: 9780128005002
Language: EN, FR, DE, ES & NL

Host Response to Biomaterials Book Review:

Host Response to Biomaterials: The Impact of Host Response on Biomaterial Selection explains the various categories of biomaterials and their significance for clinical applications, focusing on the host response to each biomaterial. It is one of the first books to connect immunology and biomaterials with regard to host response. The text also explores the role of the immune system in host response, and covers the regulatory environment for biomaterials, along with the benefits of synthetic versus natural biomaterials, and the transition from simple to complex biomaterial solutions. Fields covered include, but are not limited to, orthopaedic surgery, dentistry, general surgery, neurosurgery, urology, and regenerative medicine. Explains the various categories of biomaterials and their significance for clinical applications Contains a range of extensive coverage, including, but not limited to, orthopedic, surgery, dental, general surgery, neurosurgery, lower urinary tract, and regenerative medicine Includes regulations regarding combination devices

The Immune Response to Implanted Materials and Devices

The Immune Response to Implanted Materials and Devices
Author: Bruna Corradetti
Publsiher: Springer
Total Pages: 241
Release: 2016-11-30
ISBN 10: 3319454331
ISBN 13: 9783319454337
Language: EN, FR, DE, ES & NL

The Immune Response to Implanted Materials and Devices Book Review:

This book provides a comprehensive overview of the cascade of events activated in the body following the implant of biomaterials and devices. It is one of the first books to shed light on the role of the host immune response on therapeutic efficacy, and reviews the state-of-the-art for both basic science and medical applications. The text examines advantages and disadvantages of the use of synthetic versus natural biomaterials. Particular emphasis is placed on the role of biomimicry in the development of smart strategies able to modulate infiltrating immune cells, thus reducing side effects (such as acute and chronic inflammation, fibrosis and/or implant rejection) and improving the therapeutic outcome (healing, tissue restoration). Current cutting-edge approaches in tissue engineering, regenerative medicine, and nanomedicine offer the latest insights into the role immunomodulation in improving tolerance during tissue transplant in the treatment of orthopaedic, pancreatic, and hepatic diseases. "Immune Response to Implanted Materials and Devices" is intended for an audience of graduate students and professional researchers in both academia and industry interested in the development of smart strategies, which are able to exploit the self-healing properties of the body and achieve functional tissue restoration.

Handbook of Biomaterials Biocompatibility

Handbook of Biomaterials Biocompatibility
Author: Masoud Mozafari
Publsiher: Woodhead Publishing Limited
Total Pages: 625
Release: 2020-06
ISBN 10: 9780081029671
ISBN 13: 0081029675
Language: EN, FR, DE, ES & NL

Handbook of Biomaterials Biocompatibility Book Review:

Handbook of Biomaterials Biocompatibility is a systematic reference on host response to different biomaterials, taking into account their physical, mechanical and chemical properties. The book reviews recent progress in the design and study of biomaterials biocompatibility, along with current understanding on how to control immune system response. Sections provide the fundamental theories and challenges of biomaterials biocompatibility, the role of different biomaterials physicochemical surface properties on cell responses, cell responses to different physicochemical properties of polymers, ceramics, metals, carbons and nanomaterials, and biomaterials in different tissues, such as the cardiac, nervous system, cartilage and bone. This resource will be suitable for those working in the fields of materials science, regenerative engineering, medicine, medical devices and nanotechnology. Reviews the fundamental theories and challenges of biomaterials biocompatibility, including an overview of the standards and regulations Provides an overview on the cellular and molecular mechanisms involved in host responses to biomaterials Systematically looks at cellular response and tissue response to a wide range of biomaterials, including polymers, metals, ceramics, alloys and nanomaterials

Cellular Response to Biomaterials

Cellular Response to Biomaterials
Author: Lucy Di Silvio
Publsiher: Elsevier
Total Pages: 648
Release: 2008-12-22
ISBN 10: 184569547X
ISBN 13: 9781845695477
Language: EN, FR, DE, ES & NL

Cellular Response to Biomaterials Book Review:

The response of cells to biomaterials is critical in medical devices. Traditionally inert biomaterials were used to minimise the reaction in cells in contact with the material. However, it has been realised that specific cell responses may be beneficial in such areas as encouraging adhesion, healing or cell multiplication. Cellular response to biomaterials discusses the response of cells to a wide range of biomaterials targeted at specific medical applications. Part one discusses cell responses to a variety of polymers and ceramics with chapters on such topics as degradable polymers and biocompatibility. Part two covers cell responses and regenerative medicine with coverage of themes such as vascular grafts, nerve repair and Bioglass®. Part three examines the effect of surfaces and proteins on cell response. Specific chapters review nano-engineered surfaces, the influence of plasma proteins on bone cell adhesion and surface modification of titanium implants. With its distinguished editor and team of international contributors, Cellular response to biomaterials is an essential read for those researching or studying medical devices in industry and academia. Examines the response of cells to a wide range of biomaterials targeted at specific medical applications Discusses cell responses and regenerative medicine with specific chapters on vascular grafts and nerve repair Assesses the effect of surfaces and proteins on cell response including the influence of plasma proteins on cell adhesion and surface modification of titanium implants

Peptides and Proteins as Biomaterials for Tissue Regeneration and Repair

Peptides and Proteins as Biomaterials for Tissue Regeneration and Repair
Author: Mario Barbosa,M Cristina L Martins
Publsiher: Woodhead Publishing
Total Pages: 390
Release: 2017-09-25
ISBN 10: 008100852X
ISBN 13: 9780081008522
Language: EN, FR, DE, ES & NL

Peptides and Proteins as Biomaterials for Tissue Regeneration and Repair Book Review:

Peptides and Proteins as Biomaterials for Tissue Regeneration and Repair highlights the various important considerations that go into biomaterial development, both in terms of fundamentals and applications. After covering a general introduction to protein and cell interactions with biomaterials, the book discusses proteins in biomaterials that mimic the extracellular matrix (ECM). The properties, fabrication and application of peptide biomaterials and protein-based biomaterials are discussed in addition to in vivo and in vitro studies. This book is a valuable resource for researchers, scientists and advanced students interested in biomaterials science, chemistry, molecular biology and nanotechnology. Presents an all-inclusive and authoritative coverage of the important role which protein and peptides play as biomaterials for tissue regeneration Explores protein and peptides from the fundamentals, to processing and applications Written by an international group of leading biomaterials researchers

Monitoring and Evaluation of Biomaterials and their Performance In Vivo

Monitoring and Evaluation of Biomaterials and their Performance In Vivo
Author: Roger Narayan
Publsiher: Woodhead Publishing
Total Pages: 224
Release: 2016-11-11
ISBN 10: 0081006047
ISBN 13: 9780081006047
Language: EN, FR, DE, ES & NL

Monitoring and Evaluation of Biomaterials and their Performance In Vivo Book Review:

Monitoring and Evaluation of Biomaterials and Their Performance In Vivo provides essential information for scientists and researchers who need to assess and evaluate performance, monitor biological responses, gauge efficacy, and observe changes over time. Crucially, it also enables the optimization of design for future biomaterials and implants. This book presents readers with comprehensive coverage of the topic of in vivo monitoring of medical implants and biomaterials. Contains a specific focus on monitoring and evaluation of biomaterials in vivo Multi-faceted coverage of materials function and performance Focuses on a range of implants and subsequent bodily reactions

Oxidative Stress and Biomaterials

Oxidative Stress and Biomaterials
Author: Thomas Dziubla,D Allan Butterfield
Publsiher: Academic Press
Total Pages: 404
Release: 2016-05-31
ISBN 10: 0128032707
ISBN 13: 9780128032701
Language: EN, FR, DE, ES & NL

Oxidative Stress and Biomaterials Book Review:

Oxidative Stress and Biomaterials provides readers with the latest information on biomaterials and the oxidative stress that can pose an especially troubling challenge to their biocompatibility, especially given the fact that, at the cellular level, the tissue environment is a harsh landscape of precipitating proteins, infiltrating leukocytes, released oxidants, and fluctuations of pH which, even with the slightest shift in stasis, can induce a perpetual state of chronic inflammation. No material is 100% non-inflammatory, non-toxic, non-teratogenic, non-carcinogenic, non-thrombogenic, and non-immunogenic in all biological settings and situations. In this embattled terrain, the most we can hope for from the biomaterials we design is a type of “meso-compatibility, a material which can remain functional and benign for as long as required without succumbing to this cellular onslaught and inducing a local inflammatory reaction. Explores the challenges of designing and using biomaterials in order to minimize oxidative stress, reducing patterns of chronic inflammation and cell death Brings together the two fields of biomaterials and the biology of oxidative stress Provides approaches for the design of biomaterials with improved biocompatibility

Biomaterials Science

Biomaterials Science
Author: Buddy D. Ratner,Allan S. Hoffman,Frederick J. Schoen,Jack E. Lemons
Publsiher: Elsevier
Total Pages: 864
Release: 2004-08-18
ISBN 10: 008047036X
ISBN 13: 9780080470368
Language: EN, FR, DE, ES & NL

Biomaterials Science Book Review:

The second edition of this bestselling title provides the most up-to-date comprehensive review of all aspects of biomaterials science by providing a balanced, insightful approach to learning biomaterials. This reference integrates a historical perspective of materials engineering principles with biological interactions of biomaterials. Also provided within are regulatory and ethical issues in addition to future directions of the field, and a state-of-the-art update of medical and biotechnological applications. All aspects of biomaterials science are thoroughly addressed, from tissue engineering to cochlear prostheses and drug delivery systems. Over 80 contributors from academia, government and industry detail the principles of cell biology, immunology, and pathology. Focus within pertains to the clinical uses of biomaterials as components in implants, devices, and artificial organs. This reference also touches upon their uses in biotechnology as well as the characterization of the physical, chemical, biochemical and surface properties of these materials. Provides comprehensive coverage of principles and applications of all classes of biomaterials Integrates concepts of biomaterials science and biological interactions with clinical science and societal issues including law, regulation, and ethics Discusses successes and failures of biomaterials applications in clinical medicine and the future directions of the field Cover the broad spectrum of biomaterial compositions including polymers, metals, ceramics, glasses, carbons, natural materials, and composites Endorsed by the Society for Biomaterials

Bio Implant Interface

Bio Implant Interface
Author: J.E. Ellingsen,S.P. Lyngstadaas
Publsiher: CRC Press
Total Pages: 464
Release: 2003-04-29
ISBN 10: 1135508216
ISBN 13: 9781135508210
Language: EN, FR, DE, ES & NL

Bio Implant Interface Book Review:

Achieving good clinical outcomes with implanted biomaterials depends upon achieving optimal function, both mechanical and biological, which in turn depends upon integrating advances realized in biological science, material science, and tissue engineering. As these advances push back the frontiers of biomaterial medicine , the control and patterning

In Situ Tissue Regeneration

In Situ Tissue Regeneration
Author: Sang Jin Lee,Anthony Atala,James J Yoo
Publsiher: Academic Press
Total Pages: 458
Release: 2016-07-17
ISBN 10: 012802500X
ISBN 13: 9780128025000
Language: EN, FR, DE, ES & NL

In Situ Tissue Regeneration Book Review:

In Situ Tissue Regeneration: Host Cell Recruitment and Biomaterial Design explores the body’s ability to mobilize endogenous stem cells to the site of injury and details the latest strategies developed for inducing and supporting the body’s own regenerating capacity. From the perspective of regenerative medicine and tissue engineering, this book describes the mechanism of host cell recruitment, cell sourcing, cellular and molecular roles in cell differentiation, navigational cues and niche signals, and a tissue-specific smart biomaterial system that can be applied to a wide range of therapies. The work is divided into four sections to provide a thorough overview and helpful hints for future discoveries: endogenous cell sources; biochemical and physical cues; smart biomaterial development; and applications. Explores the body’s ability to mobilize endogenous stem cells to the site of injury Details the latest strategies developed for inducing and supporting the body’s own regenerating capacity Presents smart biomaterials in cell-based tissue engineering applications—from the cell level to applications—in the first unified volume Features chapter authors and editors who are authorities in this emerging field Prioritizes a discussion of the future direction of smart biomaterials for in situ tissue regeneration, which will affect an emerging and lucrative industry

Biological Interactions on Materials Surfaces

Biological Interactions on Materials Surfaces
Author: David A. Puleo,Rena Bizios
Publsiher: Springer Science & Business Media
Total Pages: 429
Release: 2009-06-26
ISBN 10: 9780387981611
ISBN 13: 0387981616
Language: EN, FR, DE, ES & NL

Biological Interactions on Materials Surfaces Book Review:

Success or failure of biomaterials, whether tissue engineered constructs, joint and dental implants, vascular grafts, or heart valves, depends on molecular-level events that determine subsequent responses of cells and tissues. This book presents the latest developments and state-of-the-art knowledge regarding protein, cell, and tissue interactions with both conventional and nanophase materials. Insight into these biomaterial surface interactions will play a critical role in further developments in fields such as tissue engineering, regenerative medicine, and biocompatibility of implanted materials and devices. With chapters written by leaders in their respective fields, this compendium will be the authoritative source of information for scientists, engineers, and medical researchers seeking not only to understand but also to control tissue-biomaterial interactions.

Biomimicked Biomaterials

Biomimicked Biomaterials
Author: Heung Jae Chun,Rui L. Reis,Antonella Motta,Gilson Khang
Publsiher: Springer Nature
Total Pages: 198
Release: 2020-06-29
ISBN 10: 9811532621
ISBN 13: 9789811532627
Language: EN, FR, DE, ES & NL

Biomimicked Biomaterials Book Review:

This book is the second of two volumes that together offer a comprehensive account of cutting-edge advances in the development of biomaterials for use within tissue engineering and regenerative medicine. In this volume, which is devoted to biomimetic biomaterials, the opening section discusses bone regeneration by means of duck’s feet-derived collagen scaffold and the use of decellularized extracellular matrices. The role of various novel biomimetic hydrogels in regenerative medicine is then considered in detail. The third section focuses on the control of stem cell fate by biomimetic biomaterials, covering exosome-integrated biomaterials for bone regeneration, cellular responses to materials for biomedical engineering, and the regulation of stem cell functions by micropatterned structures. Finally, the use of nano-intelligent biocomposites in regenerative medicine is addressed, with discussion of, for example, recent advances in biphasic calcium phosphate bioceramics and blood-contacting polymeric biomaterials. The authors are recognized experts in the interdisciplinary field of regenerative medicine and the book will be of value for all with an interest in regenerative medicine based on biomaterials.

Calcific Aortic Valve Disease

Calcific Aortic Valve Disease
Author: Elena Aikawa
Publsiher: BoD – Books on Demand
Total Pages: 542
Release: 2013-06-12
ISBN 10: 9535111507
ISBN 13: 9789535111504
Language: EN, FR, DE, ES & NL

Calcific Aortic Valve Disease Book Review:

Due to population aging, calcific aortic valve disease (CAVD) has become the most common heart valve disease in Western countries. No therapies exist to slow this disease progression, and surgical valve replacement is the only effective treatment. Calcific Aortic Valve Disease covers the contemporary understanding of basic valve biology and the mechanisms of CAVD, provides novel insights into the genetics, proteomics, and metabolomics of CAVD, depicts new strategies in heart valve tissue engineering and regenerative medicine, and explores current treatment approaches. As we are on the verge of understanding the mechanisms of CAVD, we hope that this book will enable readers to comprehend our current knowledge and focus on the possibility of preventing disease progression in the future.

An Introduction to Tissue Biomaterial Interactions

An Introduction to Tissue Biomaterial Interactions
Author: Kay C. Dee,David A. Puleo,Rena Bizios
Publsiher: John Wiley & Sons
Total Pages: 248
Release: 2003-04-14
ISBN 10: 0471461121
ISBN 13: 9780471461128
Language: EN, FR, DE, ES & NL

An Introduction to Tissue Biomaterial Interactions Book Review:

An Introduction to Tissue-Biomaterial Interactions acquaintsan undergraduate audience with the fundamental biological processesthat influence these sophisticated, cutting-edge procedures.Chapters one through three provide more detail about themolecular-level events that happen at the tissue-implant interface,while chapters four through ten explore selected material,biological, and physiological consequences of these events. Theimportance of the body’s wound-healing response is emphasizedthroughout. Specific topics covered include:Structure andproperties of biomaterials Proteins Protein-surface interactions Blood-biomaterial interactions Inflammation and infection The immune system Biomaterial responses to implantation Biomaterial surface engineering Intimal hyperplasia and osseointegration as examples oftissue-biomaterial interactions The text also provides extensive coverage of the three pertinentinterfaces between the body and the biomaterial, between the bodyand the living cells, and between the cells and the biomaterialthat are critical in the development of tissue-engineered productsthat incorporate living cells within a biomaterial matrix. Idealfor a one-semester, biomedical engineering course, An Introductionto Tissue-Biomaterial Interactions provides a solid framework forunderstanding today’s and tomorrow’s implantablebiomedical devices.

Bone Response to Dental Implant Materials

Bone Response to Dental Implant Materials
Author: Adriano Piattelli
Publsiher: Woodhead Publishing
Total Pages: 284
Release: 2016-10-27
ISBN 10: 0081002882
ISBN 13: 9780081002889
Language: EN, FR, DE, ES & NL

Bone Response to Dental Implant Materials Book Review:

Bone Response to Dental Implant Materials examines the oral environment and the challenges associated with dental biomaterials. Understanding different in vivo and in vitro responses is essential for engineers to successfully design and tailor implant materials which will withstand the different challenges of this unique environment. This comprehensive book reviews the fundamentals of bone responses in a variety of implant materials and presents strategies to tailor and control them. Presents a specific focus on the development and use of biomaterials in the oral environment Discusses the basic science of the dental interface and its clinical applications Contains important coverage on the monitoring and analysis of the dental implant interface

Cell Culture Technology

Cell Culture Technology
Author: Cornelia Kasper,Verena Charwat,Antonina Lavrentieva
Publsiher: Springer
Total Pages: 168
Release: 2018-10-10
ISBN 10: 3319748548
ISBN 13: 9783319748542
Language: EN, FR, DE, ES & NL

Cell Culture Technology Book Review:

This textbook provides an overview on current cell culture techniques, conditions, and applications specifically focusing on human cell culture. This book is based on lectures, seminars and practical courses in stem cells, tissue engineering, regenerative medicine and 3D cell culture held at the University of Natural Resources and Life Sciences Vienna BOKU and the Gottfried Wilhelm Leibniz University Hannover, complemented by contributions from international experts, and therefore delivers in a compact and clear way important theoretical, as well as practical knowledge to advanced graduate students on cell culture techniques and the current status of research. The book is written for Master students and PhD candidates in biotechnology, tissue engineering and biomedicine working with mammalian, and specifically human cells. It will be of interest to doctoral colleges, Master- and PhD programs teaching courses in this area of research.

Biomaterials Science

Biomaterials Science
Author: William R Wagner,Shelly E. Sakiyama-Elbert,Guigen Zhang,Michael J. Yaszemski
Publsiher: Academic Press
Total Pages: 1616
Release: 2020-05-23
ISBN 10: 0128161388
ISBN 13: 9780128161388
Language: EN, FR, DE, ES & NL

Biomaterials Science Book Review:

The revised edition of the renowned and bestselling title is the most comprehensive single text on all aspects of biomaterials science from principles to applications. Biomaterials Science, fourth edition, provides a balanced, insightful approach to both the learning of the science and technology of biomaterials and acts as the key reference for practitioners who are involved in the applications of materials in medicine. This new edition incorporates key updates to reflect the latest relevant research in the field, particularly in the applications section, which includes the latest in topics such as nanotechnology, robotic implantation, and biomaterials utilized in cancer research detection and therapy. Other additions include regenerative engineering, 3D printing, personalized medicine and organs on a chip. Translation from the lab to commercial products is emphasized with new content dedicated to medical device development, global issues related to translation, and issues of quality assurance and reimbursement. In response to customer feedback, the new edition also features consolidation of redundant material to ensure clarity and focus. Biomaterials Science, 4th edition is an important update to the best-selling text, vital to the biomaterials’ community. The most comprehensive coverage of principles and applications of all classes of biomaterials Edited and contributed by the best-known figures in the biomaterials field today; fully endorsed and supported by the Society for Biomaterials Fully revised and updated to address issues of translation, nanotechnology, additive manufacturing, organs on chip, precision medicine and much more. Online chapter exercises available for each chapter

Wound Healing Biomaterials Volume 1

Wound Healing Biomaterials   Volume 1
Author: Magnus Ågren
Publsiher: Woodhead Publishing
Total Pages: 318
Release: 2016-06-03
ISBN 10: 0081006055
ISBN 13: 9780081006054
Language: EN, FR, DE, ES & NL

Wound Healing Biomaterials Volume 1 Book Review:

Wound Healing Biomaterials: Volume One, Therapies and Regeneration discusses the types of wounds associated with trauma, illness, or surgery that can sometimes be extremely complex and difficult to heal. Consequently, there is a prominent drive for scientists and clinicians to find methods to heal these types of wounds, with science increasingly turning towards biomaterials to address these challenges. Much research is now concerned with new therapies, regeneration methods, and biomaterials to assist in wound healing and healing response. This book provides readers with a comprehensive review of the fundamentals and advances in the field of wound healing with regard to therapies and tissue regeneration. Chapters in Part One discuss fundamentals and strategies of wound healing, while Part Two reviews gene, stem cell, and drug delivery therapies for wound healing. Final chapters look at tissue regeneration strategies, making this an all-encompassing book on the topic of wound care and biomaterials. Provides more systematic and comprehensive coverage of specific therapies and biomaterials for wound healing Highlights research that is concerned with new therapies, regeneration methods, and the use of biomaterials to assist in wound healing and healing response Presents an organized layout of the material that is carefully arranged with clear titles and comprehensive section headings Looks at tissue regeneration strategies, making this an all encompassing book on the topic of wound care