Cell Based Liver Regeneration

Cell Based Liver Regeneration
Author: Hala Gabr,Wael Abo El-Kheir
Publsiher: Academic Press
Total Pages: 275
Release: 2021-09-15
ISBN 10: 9780128223406
ISBN 13: 0128223405
Language: EN, FR, DE, ES & NL

Cell Based Liver Regeneration Book Review:

Stem cell therapy is a fast-growing field of medicine with remarkable prospects in a broad spectrum of diseases. Cell-Based Liver Regeneration: Current Aspects and Future Approaches addresses the full spectrum of regenerative medicine in liver diseases. Coverage will include the basic science, current research and a comprehensive review of clinical trials conducted in the field. The book will discuss the various types of stem cells for liver regeneration, presenting the advantages and disadvantages of each type. A review of all aspects of implanting stem cell therapy for the liver, such as: choosing the cell type, the source, laboratory manipulation, dose, route and follow-up. The book concludes with a full discussion of the current clinical trials involving cellular therapy in liver regeneration. Cell-Based Liver Regeneration: Current Aspects and Future Approaches is written for stem cell biologists, liver biologists, hepatologists and graduate students by authors with extensive knowledge in basic, pre-clinical and clinical stem cell research. Introduces basic concepts of liver regeneration Discusses the various types of stem cells used in liver regeneration Explores published and ongoing clinical trials involving cellular therapy in liver regeneration

Innovative Medicine

Innovative Medicine
Author: Kazuwa Nakao,Nagahiro Minato,Shinji Uemoto
Publsiher: Springer
Total Pages: 339
Release: 2015-10-13
ISBN 10: 4431556516
ISBN 13: 9784431556510
Language: EN, FR, DE, ES & NL

Innovative Medicine Book Review:

This book is devoted to innovative medicine, comprising the proceedings of the Uehara Memorial Foundation Symposium 2014. It remains extremely rare for the findings of basic research to be developed into clinical applications, and it takes a long time for the process to be achieved. The task of advancing the development of basic research into clinical reality lies with translational science, yet the field seems to struggle to find a way to move forward. To create innovative medical technology, many steps need to be taken: development and analysis of optimal animal models of human diseases, elucidation of genomic and epidemiological data, and establishment of “proof of concept”. There is also considerable demand for progress in drug research, new surgical procedures, and new clinical devices and equipment. While the original research target may be rare diseases, it is also important to apply those findings more broadly to common diseases. The book covers a wide range of topics and is organized into three complementary parts. The first part is basic research for innovative medicine, the second is translational research for innovative medicine, and the third is new technology for innovative medicine. This book helps to understand innovative medicine and to make progress in its realization.

Regenerative Medicine Stem Cells and the Liver

Regenerative Medicine  Stem Cells and the Liver
Author: David C. Hay
Publsiher: CRC Press
Total Pages: 200
Release: 2012-04-12
ISBN 10: 1578087392
ISBN 13: 9781578087396
Language: EN, FR, DE, ES & NL

Regenerative Medicine Stem Cells and the Liver Book Review:

The regenerative capacity of the liver has been recognized for centuries, but when it is overwhelmed by insulting stimuli or is chronically damaged, its regenerative capability is substantially reduced or lost. Researchers have been working to find solutions to cure failing human liver function. Given the ability of stem cells to self- renew and differentiate into specialized cell liver types, they represent an attractive strategy to replace lost liver function. This book begins by outlining the complex nature of human liver disease and proceeds to examine the potential that stem cell-based approaches have to offer.

Scientific Engineering of Distributed Java Applications

Scientific Engineering of Distributed Java Applications
Author: Nicoals Guelfi,Egidio Astesiano,Gianna Reggio
Publsiher: Springer Science & Business Media
Total Pages: 154
Release: 2004-02-18
ISBN 10: 9783540210917
ISBN 13: 3540210911
Language: EN, FR, DE, ES & NL

Scientific Engineering of Distributed Java Applications Book Review:

This book constitutes the thoroughly refereed post-proceedings of the Third International Workshop on Scientific Engineering of Distributed Java Applications, FIDJI 2003, held in Luxembourg-Kirchberg, Luxembourg in November 2003. The 213 revised full papers presented together with abstracts of two invited contributions were carefully selected during two round of reviewing and revision from 29 submissions. Among the topics addressed are Java-enabled service gateways, mobility in distributed settings, XML, embedded Java software, interception services, mobile agents, error management, software model engineering, distributed composite objects, cooperative applications, distributed mobile applications, service-based software architectures, and distributed Java programs.

Adult Stem Cell Niches

Adult Stem Cell Niches
Author: Sabine Wislet
Publsiher: BoD – Books on Demand
Total Pages: 330
Release: 2014-08-01
ISBN 10: 9535117181
ISBN 13: 9789535117186
Language: EN, FR, DE, ES & NL

Adult Stem Cell Niches Book Review:

Tissue-specific stem cells have the capacity to self-renew and differentiate into several types of functional cells that replenish lost cells throughout an organism?s lifetime. Studies on stem cells from diverse systems have shown that stem cell function is controlled by extracellular cues from the niche and by intrinsic genetic programs within the stem cell. The objectives of this book would be to review the molecular mechanisms that mediate the balanced response of stem cells to the needs of the organisms. Likewise, niches have also been linked to pathologies, by imposing aberrant function on stem cells or other targets. Therefore, the second objective of this book would be to highligh the molecular dysregulation of niche biology leading to the disease. The third objective would be to review the therapeutical targets described within stem cell niches.

Translational Regenerative Medicine

Translational Regenerative Medicine
Author: Anthony Atala,Julie Allickson
Publsiher: Academic Press
Total Pages: 606
Release: 2014-12-01
ISBN 10: 0124104576
ISBN 13: 9780124104570
Language: EN, FR, DE, ES & NL

Translational Regenerative Medicine Book Review:

Translational Regenerative Medicine is a reference book that outlines the life cycle for effective implementation of discoveries in the dynamic field of regenerative medicine. By addressing science, technology, development, regulatory, manufacturing, intellectual property, investment, financial, and clinical aspects of the field, this work takes a holistic look at the translation of science and disseminates knowledge for practical use of regenerative medicine tools, therapeutics, and diagnostics. Incorporating contributions from leaders in the fields of translational science across academia, industry, and government, this book establishes a more fluid transition for rapid translation of research to enhance human health and well-being. Provides formulaic coverage of the landscape, process development, manufacturing, challenges, evaluation, and regulatory aspects of the most promising regenerative medicine clinical applications Covers clinical aspects of regenerative medicine related to skin, cartilage, tendons, ligaments, joints, bone, fat, muscle, vascular system, hematopoietic /immune system, peripheral nerve, central nervous system, endocrine system, ophthalmic system, auditory system, oral system, respiratory system, cardiac system, renal system, hepatic system, gastrointestinal system, genitourinary system Identifies effective, proven tools and metrics to identify and pursue clinical and commercial regenerative medicine

Regenerative Medicine Applications in Organ Transplantation

Regenerative Medicine Applications in Organ Transplantation
Author: Giuseppe Orlando
Publsiher: Academic Press
Total Pages: 1050
Release: 2013-10-11
ISBN 10: 012398520X
ISBN 13: 9780123985200
Language: EN, FR, DE, ES & NL

Regenerative Medicine Applications in Organ Transplantation Book Review:

Regenerative Medicine Applications in Organ Transplantation illustrates exactly how these two fields are coming together and can benefit one another. It discusses technologies being developed, methods being implemented, and which of these are the most promising. The text encompasses tissue engineering, biomaterial sciences, stem cell biology, and developmental biology, all from a transplant perspective. Organ systems considered include liver, renal, intestinal, pancreatic, and more. Leaders from both fields have contributed chapters, clearly illustrating that regenerative medicine and solid organ transplantation speak the same language and that both aim for similar medical outcomes. The overall theme of the book is to provide insight into the synergy between organ transplantation and regenerative medicine. Recent groundbreaking achievements in regenerative medicine have received unprecedented coverage by the media, fueling interest and enthusiasm in transplant clinicians and researchers. Regenerative medicine is changing the premise of solid organ transplantation, requiring transplantation investigators to become familiar with regenerative medicine investigations that can be extremely relevant to their work. Similarly, regenerative medicine investigators need to be aware of the needs of the transplant field to bring these two fields together for greater results. Bridges the gap between regenerative medicine and solid organ transplantation and highlights reasons for collaboration Explains the importance and future potential of regenerative medicine to the transplant community Illustrates to regenerative medicine investigators the needs of the transplant discipline to drive and guide investigations in the most promising directions

Principles of Regenerative Medicine

Principles of Regenerative Medicine
Author: Anthony Atala
Publsiher: Academic Press
Total Pages: 1182
Release: 2011
ISBN 10: 9780123814227
ISBN 13: 0123814227
Language: EN, FR, DE, ES & NL

Principles of Regenerative Medicine Book Review:

Virtually any disease that results from malfunctioning, damaged, or failing tissues may be potentially cured through regenerative medicine therapies, by either regenerating the damaged tissues in vivo, or by growing the tissues and organs in vitro and implanting them into the patient. Principles of Regenerative Medicine discusses the latest advances in technology and medicine for replacing tissues and organs damaged by disease and of developing therapies for previously untreatable conditions, such as diabetes, heart disease, liver disease, and renal failure. * Key for all researchers and instituions in Stem Cell Biology, Bioengineering, and Developmental Biology * The first of its kind to offer an advanced understanding of the latest technologies in regenerative medicine * New discoveries from leading researchers on restoration of diseased tissues and organs

Muse Cells

Muse Cells
Author: Mari Dezawa
Publsiher: Springer
Total Pages: 315
Release: 2018-11-27
ISBN 10: 4431568476
ISBN 13: 9784431568476
Language: EN, FR, DE, ES & NL

Muse Cells Book Review:

This book provides the first comprehensive account of multilineage-differentiating stress-enduring (Muse) cells, a pluripotent and non-tumorigenic subpopulation of mesenchymal stem cells (MSCs) that have the ability to detect damage signals, migrate to damaged sites, and spontaneously differentiate into cells compatible with the affected tissue, thereby enabling repair of all tissue types. The coverage encompasses everything from the basic properties of Muse cells to their tissue repair effects and potential clinical applications—for example, in acute myocardial infarction, stroke, skin injuries and ulcers, renal failure, and liver disease. An important technical chapter provides a practical and precise protocol for the isolation of Muse cells, which will enable readers to use Muse cells in their own research. In offering fascinating insights into the strategic organization of the body’s reparative function and explaining how full utilization of Muse cells may significantly enhance the effectiveness of MSC treatment, the book will be of high value for Ph.D. students, postdocs, basic researchers, clinical doctors, and industrial developers.

Liver Cirrhosis

Liver Cirrhosis
Author: Georgios Tsoulfas
Publsiher: BoD – Books on Demand
Total Pages: 178
Release: 2019-05-02
ISBN 10: 1789238854
ISBN 13: 9781789238853
Language: EN, FR, DE, ES & NL

Liver Cirrhosis Book Review:

Liver cirrhosis and its complications affect millions of patients of all ages around the globe and present treating physicians with perplexing problems, given the variety of etiologies and the critical nature of hepatic physiology. This book is a collection of chapters offering the distilled knowledge of various worldwide experts in hepatic surgery and hepatic physiology. The various debates that are presented regarding the diagnosis and treatment of liver cirrhosis and its significant complications, in addition to the most up-to-date information regarding molecular aspects, provide the reader with the full spectrum of knowledge in this challenging and continuously evolving field.

Liver Regeneration and Carcinogenesis

Liver Regeneration and Carcinogenesis
Author: Gerard Meurant
Publsiher: Elsevier
Total Pages: 402
Release: 1995-09-27
ISBN 10: 9780080535548
ISBN 13: 0080535542
Language: EN, FR, DE, ES & NL

Liver Regeneration and Carcinogenesis Book Review:

Because of its marked capacity to regenerate and the ability of chemical carcinogens and viruses to ready transform hepatocytes, the liver has been used extensively as a model for investigating the molecular mechanisms of cellular proliferation and carcinogenesis. Recently, striking advances have occured in the understanding of hepatocyte growth regulation and the manner in which chemical agents and viruses alter these normal growth regulatory pathways in liver carcinogenesis. This explosion of information has occured in a multitude of researh disciplines. This book brings together current findings in a coherent manner, from a molecular point of view. Three sections cover in detail the areas of liver regeneration, liver carcinogenesis, and liver tumor therapy. The contributors are pioneers and leaders in this field. * Logical organization of material in three detailed and comprehensive sections: liver regeneration, liver carcinogenesis, and liver tumor treatment * Contributors are pioneers and leaders in the field * There are currently no books on this subject on the market * Research focus is at the molecular level

Regenerative Biology and Medicine

Regenerative Biology and Medicine
Author: David L. Stocum
Publsiher: Academic Press
Total Pages: 474
Release: 2012-06-07
ISBN 10: 012384861X
ISBN 13: 9780123848611
Language: EN, FR, DE, ES & NL

Regenerative Biology and Medicine Book Review:

Regenerative Biology and Medicine, Second Edition — Winner of a 2013 Highly Commended BMA Medical Book Award for Medicine — discusses the fundamentals of regenerative biology and medicine. It provides a comprehensive overview, which integrates old and new data into an ever-clearer global picture. The book is organized into three parts. Part I discusses the mechanisms and the basic biology of regeneration, while Part II deals with the strategies of regenerative medicine developed for restoring tissue, organ, and appendage structures. Part III reflects on the achievements of regenerative biology and medicine; future challenges; bioethical issues that need to be addressed; and the most promising developments in regenerative medicine. The book is designed for multiple audiences: undergraduate students, graduate students, medical students and postdoctoral fellows, and research investigators interested in an overall synthesis of this field. It will also appeal to investigators from fields not directly related to regenerative biology and medicine, such as chemistry, informatics, computer science, mathematics, physics, and engineering. Highly Commended 2013 BMA Medical Book Award for Medicine Includes coverage of skin, hair, teeth, cornea, and central neural tissues Provides description of regenetive medicine in digestive, respiratory, urogenital, musculoskeletal, and cardiovascular systems Includes amphibians as powerful research models with discussion of appendage regeneration in amphibians and mammals

Stem Cell based Tissue Repair

Stem Cell based Tissue Repair
Author: Raphael Gorodetsky,Richard Schäfer
Publsiher: Royal Society of Chemistry
Total Pages: 391
Release: 2011
ISBN 10: 1849730016
ISBN 13: 9781849730013
Language: EN, FR, DE, ES & NL

Stem Cell based Tissue Repair Book Review:

This unique book by leading experts reviews the key therapeutic issues related to stem cell technology.

Liver Regeneration

Liver Regeneration
Author: Dieter Häussinger
Publsiher: Walter de Gruyter
Total Pages: 210
Release: 2011
ISBN 10: 3110250780
ISBN 13: 9783110250787
Language: EN, FR, DE, ES & NL

Liver Regeneration Book Review:

Understanding the mechanisms involved in liver regeneration is of crucial importance for clinical medicine, not only regarding carcinogenesis and diabetes treatment, but also for the use of stem cells for cell therapy and liver surgery. This graduate-level text provides an overview of the current state of knowledge of the molecular mechanisms of liver regeneration. Hepatic stem cells are introduced and the important players involved in regeneration such as oval cells, bone marrow and stellate cells are reviewed. The cell signaling pathways that initiate liver regeneration and regulate the switch between proliferation and apoptosis are presented and the role of liver stem cells in tumorigenesis is discussed. The book also treats the epigenetic regulation of liver stem cells and the roles of inflammation and angiogenesis in liver regeneration. This compact overview of the fascinating regenerative capacity of the liver will be of interest to graduate students and post-docs in molecular biology, biochemistry and medicine.

Tissue Regeneration

Tissue Regeneration
Author: Hussein Abdelhay Essayed Kaoud
Publsiher: BoD – Books on Demand
Total Pages: 206
Release: 2018-06-06
ISBN 10: 1789232600
ISBN 13: 9781789232608
Language: EN, FR, DE, ES & NL

Tissue Regeneration Book Review:

Tissue regeneration is a vast subject, with many different important aspects to consider. Regenerative medicine is a new branch of medicine that tries to change the course of chronic diseases and, in many cases, regenerates the organ systems that fail due to age, disease, damage, or genetic defects. The main purpose of this book is to point out the interest of some important topics of tissue regeneration and the progress in this field as well as the variety of different surgical fields and operations. This book includes 7 sections and 11 chapters that provide an overview of the essentials in tissue regeneration science and their potential applications in surgery. The authors of each chapter have given consolidated information on ground realities and attempted to provide a comprehensive knowledge of tissue engineering and regeneration. This book will be useful to researchers and students of biological and biomedical sciences (medical and veterinarian researchers).

In Situ Tissue Regeneration

In Situ Tissue Regeneration
Author: Sang Jin Lee,Anthony Atala,James J Yoo
Publsiher: Academic Press
Total Pages: 458
Release: 2016-07-17
ISBN 10: 012802500X
ISBN 13: 9780128025000
Language: EN, FR, DE, ES & NL

In Situ Tissue Regeneration Book Review:

In Situ Tissue Regeneration: Host Cell Recruitment and Biomaterial Design explores the body’s ability to mobilize endogenous stem cells to the site of injury and details the latest strategies developed for inducing and supporting the body’s own regenerating capacity. From the perspective of regenerative medicine and tissue engineering, this book describes the mechanism of host cell recruitment, cell sourcing, cellular and molecular roles in cell differentiation, navigational cues and niche signals, and a tissue-specific smart biomaterial system that can be applied to a wide range of therapies. The work is divided into four sections to provide a thorough overview and helpful hints for future discoveries: endogenous cell sources; biochemical and physical cues; smart biomaterial development; and applications. Explores the body’s ability to mobilize endogenous stem cells to the site of injury Details the latest strategies developed for inducing and supporting the body’s own regenerating capacity Presents smart biomaterials in cell-based tissue engineering applications—from the cell level to applications—in the first unified volume Features chapter authors and editors who are authorities in this emerging field Prioritizes a discussion of the future direction of smart biomaterials for in situ tissue regeneration, which will affect an emerging and lucrative industry

Hepatic Stem Cells

Hepatic Stem Cells
Author: Naoki Tanimizu
Publsiher: Humana Press
Total Pages: 248
Release: 2019-02-04
ISBN 10: 9781493989607
ISBN 13: 149398960X
Language: EN, FR, DE, ES & NL

Hepatic Stem Cells Book Review:

This volume looks at the liver’s epithelial cells—hepatocytes and cholangiocytes—and their progenitors. This book is divided into five parts: isolation of progenitor cells; characterization of liver progenitors in vivo; generation of hepatocytes, cholangiocytes, and their progenitors; reconstitution of liver tissue structures; and liver injury models. The chapters in this book cover topics such as expansion of bipotential liver stem/progenitor cells (LPCs) from fetal and neonatal liver; identifying progenitor cells involved in liver regeneration in vivo; methods for generating hepatocytes and cholangiocytes from multiple cellular sources; 3D tissue structures ex vivo; and resolving hepatic fibrosis by bone marrow transplantation. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Hepatic Stem Cells: Methods and Protocols is a valuable resource to help researchers understand the current theories used to study hepatic stem/progenitor cells, and aid them in performing experiments related to liver biology and pathophysiology.

Hepatocyte Transplantation

Hepatocyte Transplantation
Author: Peggy Stock,Bruno Christ
Publsiher: Humana Press
Total Pages: 365
Release: 2016-11-10
ISBN 10: 9781493965045
ISBN 13: 1493965042
Language: EN, FR, DE, ES & NL

Hepatocyte Transplantation Book Review:

This volume features up-to-date protocols for the isolation, preservation, and validation of various cell sources comprising large and small animal models, examining the impact of cell transplantation on acute and chronic liver diseases. Hepatocyte Transplantation: Methods and Protocols guides readers through laboratory protocols for the generation of humanized livers for the assessment of biological actions in vivo and techniques to monitor cell engraftment after cell transplantation in vivo are described and procedures for computational analyses of hepatocyte transplantation. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and practical, Hepatocyte Transplantation: Methods and Protocols is an essential resource for researchers and clinicians to assess the biological as well as the therapeutic potential of hepatocyte transplantation.

Cells and Biomaterials in Regenerative Medicine

Cells and Biomaterials in Regenerative Medicine
Author: Daniel Eberli
Publsiher: BoD – Books on Demand
Total Pages: 384
Release: 2014-11-26
ISBN 10: 9535117319
ISBN 13: 9789535117315
Language: EN, FR, DE, ES & NL

Cells and Biomaterials in Regenerative Medicine Book Review:

This book serves as a good starting point for anyone interested in the application of tissue engineering. It offers a colorful mix of topics, which explain the obstacles and possible solutions for TE applications. The first part covers the use of adult stem cells and their applications. The following chapters offer an insight into the development of a tailored biomaterial for organ replacement and highlight the importance of cell-biomaterial interaction. In summary, this book offers insights into a wide variety of cells, biomaterials, interfaces and applications of the next generation biotechnology, which is tissue engineering.

Organ Regeneration Based on Developmental Biology

Organ Regeneration Based on Developmental Biology
Author: Takashi Tsuji
Publsiher: Springer
Total Pages: 257
Release: 2017-03-30
ISBN 10: 981103768X
ISBN 13: 9789811037689
Language: EN, FR, DE, ES & NL

Organ Regeneration Based on Developmental Biology Book Review:

This book reviews three-dimensional (3D) stem cell culture and proof of concept for organ regeneration. The chapters present studies based on developmental biology but not tissue engineering using bio-degradative scaffolds. The ultimate goal of regenerative therapy, the next generation of regenerative therapy, is to develop fully functioning bioengineered 3D organs that can replace lost or damaged organs following disease, injury, or aging. Next-generation regenerative therapy will consist of organ-replacement regenerative therapy, which aims to reproduce reciprocal epithelial and epithelial interactions and epithelial and mesenchymal interactions that occur during embryogenesis. The book then discusses the generation of several 3D functional organs and organoids such as brain, inner ear, tooth, hair, salivary glands, lacrimal glands, gastrointestinal organs, kidney, liver, and lung. This work will appeal to a wide readership such as medical scientists, developmental biologists, clinicians, and patients. The volume provides valuable information and ideas to form a next-generation field of science.