Breaking Tolerance to Pancreatic Cancer Unresponsiveness to Chemotherapy

Breaking Tolerance to Pancreatic Cancer Unresponsiveness to Chemotherapy
Author: Ganji Purnachandra Nagaraju
Publsiher: Academic Press
Total Pages: 223
Release: 2019-02-26
ISBN 10: 0128176628
ISBN 13: 9780128176627
Language: EN, FR, DE, ES & NL

Breaking Tolerance to Pancreatic Cancer Unresponsiveness to Chemotherapy Book Review:

Breaking Tolerance to Pancreatic Cancer Unresponsiveness to Chemotherapy edited by Dr. Nagaraju, PhD., DSc. focuses on overriding the resistance from chemotherapeutic drugs with a broader range of treatment options. It particularly focuses on stroma, tumor microenvironment, stem cells, stellate cells, transcription factors, growth factors, and important signaling pathways. This volume discusses topics such as pancreatic cancer biology, current therapeutic options, EMT, chemotherapy resistance mechanisms, and genetic manipulations and natural products to enhance the sensitivity of pancreatic cancer to chemotherapy. Additionally, it discusses small targeted molecules and pancreatic cancer trials, and nanotechnology-based drug delivery. Breaking Tolerance to Pancreatic Cancer Unresponsiveness to Chemotherapy is a valuable source for researchers and advanced students in cancer and oncology as well as clinicians and medical students who are interested in learning more about ways to break pancreatic cancer resistance to chemotherapy. Modulates the biologic properties of stroma in pancreatic cancer by targeting the several chemotherapy resistance mechanisms to impede their malignant property by introducing new strategies and drugs Provides information about on-going research as well as clinical data on pancreatic cancer and detailed descriptions about therapeutic options for easy understanding Utilizes full color figures to help the understanding of the content and tables for easy comparison of information as well as quick access to it

Theranostic Approach for Pancreatic Cancer

Theranostic Approach for Pancreatic Cancer
Author: Ganji Purnachandra Nagaraju,Sarfraz Ahmad
Publsiher: Academic Press
Total Pages: 410
Release: 2019-08-19
ISBN 10: 0128194588
ISBN 13: 9780128194584
Language: EN, FR, DE, ES & NL

Theranostic Approach for Pancreatic Cancer Book Review:

Theranostic Approach for Pancreatic Cancer modulates the biologic properties of stroma in pancreatic cancer by targeting the several chemotherapy resistance mechanisms to impede their malignant property through introducing new strategies and drugs for tackling the disease. It brings information about ongoing research as well as clinical data about pancreatic cancer and provides detailed descriptions about diagnostic and therapeutic options for easy understanding. The book discusses several topics related to pancreatic cancer, such as stem cells, drug resistance and pancreatic tumor microenvironment, the latest developments in chemotherapy for metastatic cancer and chemoprevention, and epigenome as a therapeutic strategy. Additionally, it encompasses a discussion on theranostic clinical applications for personalized treatment and management of pancreatic cancer. The book is a valuable resource for cancer researchers, oncologists, and several members of the biomedical field who need to understand more about the diagnosis and treatment of pancreatic cancer. Provides information on the roadblocks of chemotherapy in patients with newly diagnosed and metastatic pancreatic cancer“/li> Discusses treatment options available currently and prospective options for the future Focuses especially on stroma, tumor microenvironment, stem cells, stellate cells, transcription factors, growth factors, and important signaling pathways as already tested types of treatment

Improving the Therapeutic Ratio in Head and Neck Cancer

Improving the Therapeutic Ratio in Head and Neck Cancer
Author: Anonim
Publsiher: Academic Press
Total Pages: 376
Release: 2019-10-04
ISBN 10: 0128178698
ISBN 13: 9780128178690
Language: EN, FR, DE, ES & NL

Improving the Therapeutic Ratio in Head and Neck Cancer Book Review:

Improving the Therapeutic Ratio in Head and Neck Cancer provides a complete review of current approaches to modulating therapeutic sensitivity in head and neck cancer. It presents a broad background of current approaches and by highlighting the potential for clinical translational, introduces a roadmap for how to move promising preclinical findings into the clinic. The book discusses topics such as immunotherapy and molecularly targeted therapies in head and neck cancer, PI3k/mTOR pathway, autophagy inhibition to sensitize HNC to radiation and chemotherapy, TAM and Eph/Ephrin family proteins and metabolic reprogramming to modulate therapeutic sensitivity. Additionally, it details approaches to improve the response to immunotherapy, and Chk1/2 inhibition in radiation and cetuximab resistance. This book is a valuable source to head and neck cancer researchers and advanced students, and to those studying specific approaches in other model systems and disease sites. Provides key scientific background for clinicians when developing novel clinical trials and important examples for basic scientists of the types of work required to move a concept from the lab to the clinic Presents consistent pathway diagrams in each chapter, thus making it easier to understand complicated pathways Includes chapter summaries of the critical next steps needed to move studies from their current state into practice changing clinical data

Drug Efflux Pumps in Cancer Resistance Pathways From Molecular Recognition and Characterization to Possible Inhibition Strategies in Chemotherapy

Drug Efflux Pumps in Cancer Resistance Pathways  From Molecular Recognition and Characterization to Possible Inhibition Strategies in Chemotherapy
Author: Anonim
Publsiher: Academic Press
Total Pages: 394
Release: 2019-11-07
ISBN 10: 0128141417
ISBN 13: 9780128141410
Language: EN, FR, DE, ES & NL

Drug Efflux Pumps in Cancer Resistance Pathways From Molecular Recognition and Characterization to Possible Inhibition Strategies in Chemotherapy Book Review:

Drug Efflux Pumps in Cancer Resistance Pathways: From Molecular Recognition and Characterization to Possible Inhibition Strategies in Chemotherapy, Volume Seven, describes the fundamental aspects of efflux pumps of the ATP-binding cassette superfamily in cancer resistance pathways, along with strategies to target and improve chemotherapy efficacy. Pumps of the ATP-binding cassette superfamily (ABCs) regulate the access of drugs to the intracellular space. In this context, the overexpression of ABCs is a well-known mechanism of multidrug resistance in cancer and is associated with therapeutic failure. Cancer types discussed include breast, endocrine, hematologic, gastrointestinal, musculoskeletal, lung, skin and central nervous system cancers. The book is a valuable source for researchers and advanced students in cancer, biology, pharmacology, pharmaceutical sciences, biomaterials and medical/clinical sciences that are interested in accessing a comprehensive compendium on efflux pumps in mechanisms of cancer resistance. Offers comprehensive and detailed descriptions of the basic aspects of efflux pumps in a very schematic and didactic manner Describes the involvement of efflux pumps in cancer resistance in different cancer types Encompasses an updated overview on state-of-the-art approaches that capitalize on their inhibition to improve chemotherapy and overcome resistance

Therapeutic Strategies to Overcome ALK Resistance in Cancer

Therapeutic Strategies to Overcome ALK Resistance in Cancer
Author: Luc Friboulet
Publsiher: Academic Press
Total Pages: 216
Release: 2021-01-18
ISBN 10: 0128217790
ISBN 13: 9780128217795
Language: EN, FR, DE, ES & NL

Therapeutic Strategies to Overcome ALK Resistance in Cancer Book Review:

Therapeutic Strategies to Overcome ALK Resistance in Cancer, Volume 13, presents current strategies to improve and prolong clinical benefit in ALK driven cancers. Most patients with ALK-driven cancer are sensitive to tyrosine kinase inhibitor (TKI) therapy, but resistance invariably develops. This book discusses topics such as structure and function of ALK, ALK rearranged lung cancer, resistance mechanisms to ALK TKI tumors, and novel therapeutic strategies to enhance crizotinib anti-tumor efficacy in ALCL. Additionally, it encompasses information on drug combinations to enhance ALK TKI anti-tumor efficacy in neuroblastoma and future perspectives in the field. This book is a valuable resource for cancer researchers, clinicians and several members of biomedical field who need to understand more about how to fight ALK resistance in cancer treatment. Explains the biology of ALK RTK, focusing on its tissue expression, structure and functionality Presents an overview of current treatments and the benefits of ALK TKI in lung and other cancer types, such as ALCL, neuroblastoma and inflammatory myofibroblastic tumor Encompasses information on systemic treatments other than TKI, including chemotherapy, immunotherapy and antiangiogenic agents in ALK-driven NSCLC

A Theranostic and Precision Medicine Approach for Female Specific Cancers

A Theranostic and Precision Medicine Approach for Female Specific Cancers
Author: Rama Rao Malla,Ganji Purnachandra Nagaraju
Publsiher: Academic Press
Total Pages: 318
Release: 2020-11-06
ISBN 10: 0128226927
ISBN 13: 9780128226926
Language: EN, FR, DE, ES & NL

A Theranostic and Precision Medicine Approach for Female Specific Cancers Book Review:

A Theranostic and Precision Medicine Approach for Female-Specific Cancers provides information regarding ongoing research and clinical data surrounding female specific cancers (breast, cervical, ovarian and endometrial cancers). The book encompasses detailed descriptions about diagnostics and therapeutic options for easy understanding, focusing on the subject matter with a broader range of treatment options. In addition, it explores new theranostics, i.e., diagnostic, therapeutic and precision medicine strategies currently being developed for FSCs. This book is a valuable resource for cancer researchers, clinicians, graduate students and other members of biomedical field who need to understand the most recent and promising approaches to manage FSCs. Explores new diagnostic biomarkers surrounding the early detection and prognosis of FSCs Examines new genetic and molecularly targeted approaches for the treatment of these aggressive diseases Discusses new theranostic approaches that combine diagnosis and treatment through the use of nanotechnology in FSCs Addresses how these various advances can be integrated into a precision and personalized medicine approach that can eventually enhance patient care

Molecular Mechanisms of Tumor Cell Resistance to Chemotherapy

Molecular Mechanisms of Tumor Cell Resistance to Chemotherapy
Author: Benjamin Bonavida
Publsiher: Springer Science & Business Media
Total Pages: 260
Release: 2013-07-04
ISBN 10: 1461470706
ISBN 13: 9781461470700
Language: EN, FR, DE, ES & NL

Molecular Mechanisms of Tumor Cell Resistance to Chemotherapy Book Review:

​​​​​This volume gives the latest developments in on the mechanisms of cancer cell resistance to apoptotic stimuli, which eventually result in cancer progression and metastasis. One of the main challenges in cancer research is to develop new therapies to combat resistant tumors. The development of new effective therapies will be dependent on delineating the biochemical, molecular, and genetic mechanisms that regulate tumor cell resistance to cytotoxic drug-induced apoptosis. These mechanisms should reveal gene products that directly regulate resistance in order to develop new drugs that target these resistance factors and such new drugs may either be selective or common to various cancers. If successful, new drugs may not be toxic and may be used effectively in combination with subtoxic conventional drugs to achieve synergy and to reverse tumor cell resistance. The research developments presented in this book can be translated to produce better clinical responses to resistant tumors.

Role of Transcription Factors in Gastrointestinal Malignancies

Role of Transcription Factors in Gastrointestinal Malignancies
Author: Ganji Purnachandra Nagaraju,Pallaval Veera Bramhachari
Publsiher: Springer
Total Pages: 513
Release: 2018-03-27
ISBN 10: 9811067287
ISBN 13: 9789811067280
Language: EN, FR, DE, ES & NL

Role of Transcription Factors in Gastrointestinal Malignancies Book Review:

This book illustrates the importance of transcription factors in gastrointestinal cancer progression and metastasis with regard to understanding the mechanism and target definition in drug discovery. Further, it describes the complex issues associated with cancer cell growth and metastasis. The respective chapters provide detailed information on the various types of transcription factors (NF-kB, HIF-1, STAT-3, E2F1, and Sp1) and gastric-associated cancers (esophagus, stomach, colorectal, liver and pancreatic cancers) in connection with specific functional studies like cell cycle, angiogenesis, migration, invasion and apoptosis. These transcription factors control the expression of several signaling pathways involved in tumor growth, making them ideal targets for gastrointestinal cancer therapy. In closing, the book provides comprehensive descriptions of the major challenges associated with gastrointestinal cancer therapy.

Role of Nutraceuticals in Cancer Chemosensitization

Role of Nutraceuticals in Cancer Chemosensitization
Author: Anonim
Publsiher: Academic Press
Total Pages: 398
Release: 2017-10-18
ISBN 10: 0128123745
ISBN 13: 9780128123744
Language: EN, FR, DE, ES & NL

Role of Nutraceuticals in Cancer Chemosensitization Book Review:

Role of Nutraceuticals in Chemoresistance to Cancer, Volume Two, focuses on nutraceuticals, the compounds derived from natural sources, which are usually multi-targeted as a means to overcome chemoresistance. This book discusses the role of several compounds related to nutraceuticals and chemoresistance, such as curcumin, resveratrol, indole 3-carbinol, tocotrienols, ursolic acid, fisetin, celastrol, gambogic, butein, catechins and silymarin. It is a valuable resource for cancer researchers, oncologists and members of several areas of the biomedical field who are interested in understanding how to use nutraceuticals as a sensitizing agent for chemotherapy. Brings updated information on natural compounds used as specific inhibitors of cell signaling pathways as reviewed by experts in the field Presents experts analysis and summary of reported and novel findings and potential translational application in cancer patients Describes molecular mechanisms with new and helpful approaches for the readers to use in their own investigations

100 Cases in Clinical Medicine Second Edition

100 Cases in Clinical Medicine  Second Edition
Author: John Rees,James Pattison,Gwyn Williams
Publsiher: CRC Press
Total Pages: 272
Release: 2011-12-09
ISBN 10: 1444166557
ISBN 13: 9781444166552
Language: EN, FR, DE, ES & NL

100 Cases in Clinical Medicine Second Edition Book Review:

100 Cases in Clinical Medicine is an indispensable revision tool for medical students preparing for clinical examinations or OSCEs. Using scenarios which mimic daily life, the cases will interest students in clinical problems and help them develop their clinical reasoning skills, with each case presenting details of a patient's medical history and the key findings of a clinical examination, together with initial investigation results for evaluation. Key questions then prompt the student to evaluate the patient, and reach a decision regarding their condition and the possible management plan, while the answer pages will help the student to understand the processes that a clinician goes through in dealing with the problems presented. Contents are organised to provide a quick review of each body system, with a selection of cases relevant to that specific system, then the majority are presented randomly to mimic real life in a GP surgery or emergency department. New to this edition: a review of each body system as well as random cases; new page design with a second colour used throughout; and brought up-to-date with 25% new cases.

Cancer in Children

Cancer in Children
Author: Michael C. G. Stevens,Hubert N. Caron,Andrea Biondi
Publsiher: Oxford University Press
Total Pages: 400
Release: 2012
ISBN 10: 0199599416
ISBN 13: 9780199599417
Language: EN, FR, DE, ES & NL

Cancer in Children Book Review:

This new edition brings together an international group of highly respected editors and contributors to provide evidence-based information on how to investigate and treat the common cancers in childhood. In a clear and concise way, it covers the aetiology, symptoms, and treatment of cancer in children, the complications that can arise during treatment, and the various outcomes of the illness. State-of-the-art descriptions of what is basic and essential for management is included; there are new chapters on clinical trials, evidence based practice, the treatment of cancer in less well-resourced countries, stem cell and immunotherapy, other malignant / borderline haematological conditions (myelodysplasia and myeloproliferative disorders), and on imaging. These all reflect important changes in the focus of the speciality in recent years. Aimed at paediatric oncologists, and trainees in oncology and paediatrics, this leading text will also appeal to paediatric nurses, cancer nurses, and paramedical paediatric staff.

Immunotherapy of Cancer

Immunotherapy of Cancer
Author: Yoshiyuki Yamaguchi
Publsiher: Springer
Total Pages: 358
Release: 2016-02-22
ISBN 10: 4431550313
ISBN 13: 9784431550310
Language: EN, FR, DE, ES & NL

Immunotherapy of Cancer Book Review:

This timely book, published just as cancer immunotherapy comes of age, summarizes the rationale, present status, and future perspective for cancer immunotherapy. Included are explanations of the constitution of the immune system and immunocheckpoints, the mechanism of antigen presentation and recognition, valuable modalities, clinical trials and guidance, personalization, and biomarkers, all of which are essential for understanding the success of cancer immunotherapy. This innovative therapy has been investigated worldwide as the fourth line of cancer treatment after the standard treatments of surgery, chemotherapy, and radiotherapy. The progress in fundamental understanding of tumor immunology and the recent advances in clinical trials have opened new avenues with a cancer vaccine in 2010 and immunocheckpoint modulation in 2011, with their approval already granted in the United States. Today, there are no doubts, even among experts in cancer chemotherapy and radiotherapy, that the immune system plays a vital role in tumor eradication. Following American approval, many clinical trials of cancer immunotherapy are being conducted. With this book the reader will readily understand the paradigm shift in cancer treatment and will realize the importance of cancer immunotherapy. The great value of immunotherapy will be obvious, not only for tumor shrinkage but for prolonging patient survival.

Role of Tyrosine Kinases in Gastrointestinal Malignancies

Role of Tyrosine Kinases in Gastrointestinal Malignancies
Author: Ganji Purnachandra Nagaraju
Publsiher: Springer
Total Pages: 241
Release: 2018-09-27
ISBN 10: 9811314861
ISBN 13: 9789811314865
Language: EN, FR, DE, ES & NL

Role of Tyrosine Kinases in Gastrointestinal Malignancies Book Review:

The aim of this book is to provide comprehensive overview of the role of different tyrosine kinases in the progression and metastasis of various cancers of the gastrointestinal tract such as esophagus, liver, pancreas, stomach, and colorectal. Activation of various signaling pathways and tyrosine kinases are responsible for resistance to chemo and radiotherapy in these gastrointestinal malignancies. Targeting these tyrosine kinases, which regulate the activities of survival pathways in growth, and metastasis is a rational strategy in gastrointestinal cancer therapy. Each chapter embedded in this book covers information pertaining to a specific tyrosine kinase and its impact on various malignancies, which is not only significant for basic and clinical research investigations but will also be valued by students at advanced undergraduate to postgraduate levels.

Toxicological Survey of African Medicinal Plants

Toxicological Survey of African Medicinal Plants
Author: Victor Kuete
Publsiher: Elsevier
Total Pages: 744
Release: 2014-05-30
ISBN 10: 0128004754
ISBN 13: 9780128004753
Language: EN, FR, DE, ES & NL

Toxicological Survey of African Medicinal Plants Book Review:

Toxicological Survey of African Medicinal Plants provides a detailed overview of toxicological studies relating to traditionally used medicinal plants in Africa, with special emphasis on the methodologies and tools used for data collection and interpretation. The book considers the physical parameters of these plants and their effect upon various areas of the body and human health, including chapters dedicated to genotoxicity, hepatotoxicity, nephrotoxicity, cardiotoxicity, neurotoxicity, and specific organs and systems. Following this discussion of the effects of medicinal plants is a critical review of the guidelines and methods in use for toxicological research as well as the state of toxicology studies in Africa. With up-to-date research provided by a team of experts, Toxicological Survey of African Medicinal Plants is an invaluable resource for researchers and students involved in pharmacology, toxicology, phytochemistry, medicine, pharmacognosy, and pharmaceutical biology. Offers a critical review of the methods used in toxicological survey of medicinal plants Provides up-to-date toxicological data on African medicinal plants and families Serves as a resource tool for students and scientists in the various areas of toxicology

Advanced Concepts in Human Immunology Prospects for Disease Control

Advanced Concepts in Human Immunology  Prospects for Disease Control
Author: Pooja Jain
Publsiher: Springer Nature
Total Pages: 329
Release: 2021
ISBN 10: 3030339467
ISBN 13: 9783030339463
Language: EN, FR, DE, ES & NL

Advanced Concepts in Human Immunology Prospects for Disease Control Book Review:

Surgical Techniques in Rectal Cancer

Surgical Techniques in Rectal Cancer
Author: Giovanni Dapri,John H Marks
Publsiher: Springer
Total Pages: 603
Release: 2018-02-09
ISBN 10: 443155579X
ISBN 13: 9784431555797
Language: EN, FR, DE, ES & NL

Surgical Techniques in Rectal Cancer Book Review:

This book describes the various procedures, including surgery through the abdominal wall, through a transanal access or by the union of both, using an open, laparoscopic, or robotic approach. Worldwide pioneers for each technique are invited as authors and portray in step-by-step detail about each procedure. Of the 32 chapters, 23 are dedicated only for the surgical procedures. Each chapter is enriched by numerous figures, which complement the text, permitting the understanding of each surgical technique from its beginning until the last step. Eight additional chapters are dedicated to the clinical and anatomical aspects of rectal cancer. In the last decade there has been an impressive evolution in the treatment of patients with rectal cancer, with a focus not only on the preservation of a cancer-free life, but the quality of that life. This book has been written to be useful for everyone involved in rectal cancer management. From internists, gastroenterologists, endoscopists, oncologists, radiotherapists and radiologists involved in the treatment of rectal cancer during their daily practice, to surgeons specialized in colorectal surgery, to junior faculty to trainees, all interested in new and innovative techniques.

Mucosal Health in Aquaculture

Mucosal Health in Aquaculture
Author: Benjamin H. Beck,Eric Peatman
Publsiher: Academic Press
Total Pages: 408
Release: 2015-02-17
ISBN 10: 0124171931
ISBN 13: 9780124171930
Language: EN, FR, DE, ES & NL

Mucosal Health in Aquaculture Book Review:

Mucosal Health in Aquaculture is an essential reference on mucosal health for the diverse aquaculture community. Rich in explanatory figures and schematics, the book includes important concepts such as structural and cellular composition of mucosal surfaces in fish and shellfish, known functional roles of molecular and cellular actors during pathogen invasion, impacts of nutrition on the mucosal barriers, impacts of chemical treatments on mucosal surfaces, mucosal vaccines and vaccination strategies, and more. The health of cultured aquaculture species is critical in establishing the sustainable growth of the aquaculture industry worldwide, and mucosal health is of particular interest to those working in aquaculture because mucosal surfaces (skin, gill, intestine, reproductive tissues) constitute the first line of defense against pathogen invasion. Mucosal Health in Aquaculture captures the latest research on mucosal barriers in aquaculture species and their impacts on nutrition and immunity to ensure sustainable aquaculture development. Includes research case studies to exhibit the importance of various integrated approaches to mucosal health Examines the latest scientific methods and technologies to maximize efficiencies for healthy fish production for farming Brings together the latest knowledge and research on mucosal barriers and mechanisms from world-wide experts in mucosal health Utilizes detailed diagrams and figures to enhance comprehension

Physics of Cancer

Physics of Cancer
Author: Claudia Mierke
Publsiher: Iph001
Total Pages: 500
Release: 2018-10-24
ISBN 10: 9780750317511
ISBN 13: 0750317515
Language: EN, FR, DE, ES & NL

Physics of Cancer Book Review:

This revised second edition is improved linguistically with multiple increases of the number of figures and the inclusion of several novel chapters such as actin filaments during matrix invasion, microtubuli during migration and matrix invasion, nuclear deformability during migration and matrix invasion, and the active role of the tumor stroma in regulating cell invasion.

Medicinal Plant Research in Africa

Medicinal Plant Research in Africa
Author: Victor Kuete
Publsiher: Newnes
Total Pages: 916
Release: 2013-06-19
ISBN 10: 0124059368
ISBN 13: 9780124059368
Language: EN, FR, DE, ES & NL

Medicinal Plant Research in Africa Book Review:

The pharmacopoeias of most African countries are available and contain an impressive number of medicinal plants used for various therapeutic purposes. Many African scholars have distinguished themselves in the fields of organic chemistry, pharmacology, and pharmacognosy and other areas related to the study of plant medicinal plants. However, until now, there is no global standard book on the nature and specificity of chemicals isolated in African medicinal plants, as well as a book bringing together and discussing the main bioactive metabolites of these plants. This book explores the essence of natural substances from African medicinal plants and their pharmacological potential. In light of possible academic use, this book also scans the bulk of African medicinal plants extract having promising pharmacological activities. The book contains data of biologically active plants of Africa, plant occurring compounds and synthesis pathways of secondary metabolites. This book explores the essence of natural substances from African medicinal plants and their pharmacological potential The authors are world reknowned African Scientists.

Management of rare adult tumours

Management of rare adult tumours
Author: Yazid Belkacemi,René-Olivier Mirimanoff,Mahmut Ozsahin
Publsiher: Springer Science & Business Media
Total Pages: 600
Release: 2011-02-02
ISBN 10: 9782287922466
ISBN 13: 2287922466
Language: EN, FR, DE, ES & NL

Management of rare adult tumours Book Review:

Why a book dedicated to rare cancer management? Given the large variety of rare cancers,they take up a significant part of our daily practice. Therefore, we owe it to our patients with rare tumours that we use the knowledge gained in the treatment of the more common cancers to provide them with a better future. This knowledge comes from recent developments in molecular diagnostics, systemic treatments with new drugs and targeted therapies together with advanced technologies in the areas of radiology and radiation therapy. Our authors have analysed the literature and recommend treatments for rare cancers based on results from past studies. We hope that this book will be an aid to those treating rare cancer cases about which, up to now, little has been published, and will reassure our patients that they have not been forgotten.