Brain Metastases from Primary Tumors

Brain Metastases from Primary Tumors
Author: M. A. Hayat
Publsiher: Academic Press
Total Pages: 236
Release: 2015-01-05
ISBN 10: 9780128014196
ISBN 13: 0128014199
Language: EN, FR, DE, ES & NL

Brain Metastases from Primary Tumors Book Review:

With an annual rate of more than 12 million global diagnoses and 7.6 million deaths, the societal and economic burden of cancer cannot be overstated. Brain metastases are the most common malignant tumors of the central nervous system, yet their incidence appears to be increasing in spite of the advancement of cancer therapies. While much is known about primary cancers (including primary brain tumors), less work has been done to uncover the roots of metastatic disease. This volume fills that gap, serving as the first reference to focus primarily on the link between primary cancers and brain.

Brain Metastases from Primary Tumors Volume 3

Brain Metastases from Primary Tumors  Volume 3
Author: M. A. Hayat
Publsiher: Academic Press
Total Pages: 384
Release: 2016-04-07
ISBN 10: 0128035595
ISBN 13: 9780128035597
Language: EN, FR, DE, ES & NL

Brain Metastases from Primary Tumors Volume 3 Book Review:

Brain Metastases from Primary Tumors Volume Three: Epidemiology, Biology, and Therapy of Melanoma and Other Cancers provides a comprehensive overview of the metastasis of cancer, the main cause of approximately 90% of cancer associated deaths, yet the mechanisms governing this clinically important process remain poorly understood. Melanoma is the third most common diagnosis among patients with brain metastases, after lung and breast cancer. Approximately 75% of patients with metastatic melanoma develop brain metastases during the course of their disease. Although tumorigenesis of melanoma remains poorly understood, recent advances in gene expression profiling have revealed molecular mechanisms of this deadly disease. In addition, high-throughput gene expression has many advantages over techniques in cancer transcriptomic studies and has led to the discovery of numerous diagnostic, prognostic, and therapeutic targets, which are also detailed in this book. The book discusses the link between primary tumors and brain metastasis of melanoma, including molecular mechanisms, treatment options, prognosis, and general applications. Comprehensive chapters discuss systemic therapy, integrin inhibitors, stereotaxic radiosurgery, and more, making this book a great resource for neurooncologists, neurosurgeons, neurologists, and cancer researchers. Presents the only comprehensive reference detailing the link between primary cancers and brain metastases in melanoma Aids the target audience in discussing various treatment options for patients with brain metastases from melanoma Edited work with chapters authored by leaders in the field around the globe – the broadest, most expert coverage available

Brain Metastases from Primary Tumors

Brain Metastases from Primary Tumors
Author: M. A. Hayat
Publsiher: Unknown
Total Pages: 329
Release: 2014
ISBN 10:
ISBN 13: OCLC:940512388
Language: EN, FR, DE, ES & NL

Brain Metastases from Primary Tumors Book Review:

With an annual rate of more than 12 million global diagnoses and 7.6 million deaths, the societal and economic burden of cancer cannot be overstated. Brain metastases are the most common malignant tumors of the central nervous system, yet their incidence appears to be increasing in spite of the advancement of cancer therapies. While much is known about primary cancers (including primary brain tumors), less work has been done to uncover the roots of metastatic disease. This volume fills that gap, serving as the first reference to focus primarily on the link between primary cancers and brain.--

Brain Metastases from Primary Tumors Volume 1

Brain Metastases from Primary Tumors Volume 1
Author: M. A. Hayat
Publsiher: Academic Press
Total Pages: 274
Release: 2014-04-03
ISBN 10: 0128010959
ISBN 13: 9780128010952
Language: EN, FR, DE, ES & NL

Brain Metastases from Primary Tumors Volume 1 Book Review:

With an annual rate of more than 12 million global diagnoses and 7.6 million deaths, the societal and economic burden of cancer cannot be overstated. Brain metastases are the most common malignant tumors of the central nervous system, yet their incidence appears to be increasing in spite of the advancement of cancer therapies. While much is known about primary cancers (including primary brain tumors), less work has been done to uncover the roots of metastatic disease. Brain Metastases from Primary Tumors Volume 1 fills that gap, serving as the first reference to focus primarily on the link between primary cancers and brain metastases. This link is explored for the most common cancer types – lung, breast, and melanoma. Additionally, biological background as well as therapy for CNS metastases is addressed. Age and gender related trends are also discussed, as is the use of biomarkers for early detection. The only comprehensive reference detailing the link between primary cancers and brain metastases Aids the target audience in determining the incidence of brain metastases in patients with a primary cancer Provided education about the potential use of biomarkers for early detection, diagnosis and prevention of the spread of primary cancer to the brain Documents temporal and gender-related trends in brain metastases from other cancers Edited work with chapters authored by leaders in the field around the globe – the broadest, most expert coverage available

Cancer Management and Therapy

Cancer Management and Therapy
Author: Amal Hamza,Neveen Salem
Publsiher: BoD – Books on Demand
Total Pages: 210
Release: 2018-06-20
ISBN 10: 1789232988
ISBN 13: 9781789232981
Language: EN, FR, DE, ES & NL

Cancer Management and Therapy Book Review:

There are many different types of cancer. Some are very common; others are rare. Having some similar features, each cancer has its own characteristics and symptoms, which vary according to the type of cancer and where it is in the body. The treatment selected may be influenced by the patient's age, concurrent health problems, life expectancy, characteristics of the individual's cancer, the patient's goals of treatment, and the bias of the treating physician. In preparing this book, we have considered and reflected on the concept of the recent advances in cancer management and therapy as well as molecular applications in cancer therapy. The readers can find detailed information about the treatment and management of specific cancers in these book chapters.

Central Nervous System Metastases

Central Nervous System Metastases
Author: Manmeet Ahluwalia,Philippe Metellus,Riccardo Soffietti
Publsiher: Springer
Total Pages: 421
Release: 2020-11-29
ISBN 10: 9783030234195
ISBN 13: 3030234193
Language: EN, FR, DE, ES & NL

Central Nervous System Metastases Book Review:

This book provides a comprehensive overview of brain metastases, from the molecular biology aspects to therapeutic management and perspectives. Due to the increasing incidence of these tumors and the urgent need to effectively control brain metastatic diseases in these patients, new therapeutic strategies have emerged in recent years. The volume discusses all these innovative approaches combined with new surgical techniques (fluorescence, functional mapping, integrated navigation), novel radiation therapy techniques (stereotactic radiosurgery) and new systemic treatment approaches such as targeted- and immunotherapy. These combination strategies represent a new therapeutic model in brain metastatic patients in which each medical practitioner (neurosurgeon, neurologist, medical oncologist, radiation oncologist) plays a pivotal role in defining the optimal treatment in a multidisciplinary approach. Written by recognized experts in the field, this book is a valuable tool for neurosurgeons, neuro-oncologists, neuroradiologists, medical oncologists, radiation oncologists, cognitive therapists, basic scientists and students working in the area of brain tumors.

Brain Metastases from Primary Tumors Volume 1

Brain Metastases from Primary Tumors Volume 1
Author: M. A. Hayat
Publsiher: Academic Press
Total Pages: 274
Release: 2014-04-24
ISBN 10: 9780128008966
ISBN 13: 0128008962
Language: EN, FR, DE, ES & NL

Brain Metastases from Primary Tumors Volume 1 Book Review:

With an annual rate of more than 12 million global diagnoses and 7.6 million deaths, the societal and economic burden of cancer cannot be overstated. Brain metastases are the most common malignant tumors of the central nervous system, yet their incidence appears to be increasing in spite of the advancement of cancer therapies. While much is known about primary cancers (including primary brain tumors), less work has been done to uncover the roots of metastatic disease. Brain Metastases from Primary Tumors Volume 1 fills that gap, serving as the first reference to focus primarily on the link between primary cancers and brain metastases. This link is explored for the most common cancer types - lung, breast, and melanoma. Additionally, biological background as well as therapy for CNS metastases is addressed. Age and gender related trends are also discussed, as is the use of biomarkers for early detection. The only comprehensive reference detailing the link between primary cancers and brain metastases Aids the target audience in determining the incidence of brain metastases in patients with a primary cancer Provided education about the potential use of biomarkers for early detection, diagnosis and prevention of the spread of primary cancer to the brain Documents temporal and gender-related trends in brain metastases from other cancers Edited work with chapters authored by leaders in the field around the globe - the broadest, most expert coverage available

Brain Metastases

Brain Metastases
Author: Jeffrey Raizer,Lauren E. Abrey
Publsiher: Springer Science & Business Media
Total Pages: 239
Release: 2007-10-03
ISBN 10: 0387692215
ISBN 13: 9780387692210
Language: EN, FR, DE, ES & NL

Brain Metastases Book Review:

Brain metastases are the most dreaded complication of systemic cancer, affecting some 170,000 people a year, a far greater incidence than primary brain tumors. This book presents current information on the presentation and management of patients with brain metastases, providing available data, giving guidelines that can be applied in day to day practice, updated information for neurosurgeons, radiation oncologists, medical oncologists, and neuron-oncologists, and as an overview for physicians in training.

Brain Metastases

Brain Metastases
Author: Mikhail Dolgushin,Valery Kornienko,Igor Pronin
Publsiher: Springer
Total Pages: 469
Release: 2017-10-30
ISBN 10: 3319577603
ISBN 13: 9783319577609
Language: EN, FR, DE, ES & NL

Brain Metastases Book Review:

This book describes the role of advanced neuroimaging techniques in characterizing the changes in tissue structure in patients with brain metastases. On a large number of newly recognized CT, MRI, and PET characteristics of brain metastases from different primary tumors are highlighted, thereby elucidating the potential differential diagnostic role of CT perfusion imaging, MR spectroscopy, MR diffusion-weighted imaging, MR susceptibility-weighted imaging, and PET with different radiopharmaceuticals. For example, the different manifestations of metastases of melanoma, renal cell carcinoma, and ovarian cancer on MRI and CT perfusion imaging are described, and the role of MR susceptibility-weighted imaging in the differential diagnosis of glioblastoma multiforme and metastatic tumors is clarified. Metastases of colon cancer have shown a special manifestation on T2 weighted images. The book also presents novel findings regarding pathogenesis and tumor biology and describes qualitative and quantitative changes in tumor tissue and alterations in brain white matter due to surrounding tumor growth. Neuroradiologists and others, including neurosurgeons, neurologists, and nuclear medicine physicians, will find that this book offers a fascinating insight into the ways in which newly available data on structural, hemodynamic, and metabolic changes are enriching the neuroimaging of brain metastases.

Cancer Medicine

Cancer Medicine
Author: James F. Holland
Publsiher: Unknown
Total Pages: 3467
Release: 1997
ISBN 10: 9780683040951
ISBN 13: 0683040952
Language: EN, FR, DE, ES & NL

Cancer Medicine Book Review:

Tumors of the Central Nervous System Volume 4

Tumors of the Central Nervous System  Volume 4
Author: M.A. Hayat
Publsiher: Springer Science & Business Media
Total Pages: 386
Release: 2011-09-15
ISBN 10: 9789400717060
ISBN 13: 9400717067
Language: EN, FR, DE, ES & NL

Tumors of the Central Nervous System Volume 4 Book Review:

This volume mainly contains information on the diagnosis, therapy, and prognosis of brain tumors. Insights on the understanding of molecular pathways involved in tumor biology are explained, which should lead to the development of effective drugs. Information on pathways (e.g., hedgehog) facilitates targeted therapies in cancer. Tumor models are also presented, which utilize expression data, pathway sensitivity, and genetic abnormalities, representing targets in cancer. For example, rat model of malignant brain tumors using implantation of doxorubicin with drug eluting beads for delivery is explained. The future of pathway-driven therapies for tumors is summarized. The importance of personalizing cancer care is emphasized. The need for supportive measures for survivors of brain cancer is pointed out, so is the quality of life monitoring. The need of rehabilitation therapy for patients with primary and metastatic brain tumors is also emphasized. Role of MicroRNA in distinguishing primary tumors from metastatic primary tumors is discussed. Advantages and limitations of chemotherapy (e.g., temozolomide and doxorubicin) are discussed. The complexity of tumor to tumor transfer is explained; examples discussed are: brain metastases from breast cancer and brain metastases fro non-small cell lung carcinoma. Identification and characterization of biomarkers, including those for metastatic brain tumors, are presented. Genomic analysis for identifying clinically relevant subtypes of glioblastoma is included. A large number of imaging modalities are detailed to study progression and invasion of gliomas

Metastatic Cancer Clinical and Biological Perspectives

Metastatic Cancer  Clinical and Biological Perspectives
Author: Rahul Jandial
Publsiher: CRC Press
Total Pages: 312
Release: 2013-08-08
ISBN 10: 9781587066597
ISBN 13: 1587066599
Language: EN, FR, DE, ES & NL

Metastatic Cancer Clinical and Biological Perspectives Book Review:

Most cancer deaths are a result of metastasis. The spread of a primary tumor to colonize neighboring and distant organs is the relentless endgame that defines the neoplastic process. Patients who have been diagnosed with cancer are treated to prevent both the recurrence of the tumor at the site of origin and metastasis that would re-stage them as advanced stage IV cancer. Historically and still with some types of cancer, stage IV is perceived by patients as “terminal.” Fortunately, recent molecular therapies have extended the lives of patients with advanced cancer and reassuringly people living with metastatic disease increasingly visit our clinics. What is the path forward? Given that the consilience of science and medicine is a dynamic art from which therapies arise, it would be misguided to consider any single work adequate at capturing the horizon for research. So with humility we constructed this text as primer for scientists. It begins with a broad introduction to the clinical management of common cancers. This is intended to serve as a foundation for investigators to consider when developing basic science hypotheses. Unquestionably, medical and surgical care of cancer patients reveals biology and dictates how novel therapeutics will ultimately be evaluated in clinical trials. The second section of this text offers provocative and evolving insights that underscore the breadth of science involved in the elucidation of cancer metastasis biology. The text concludes with information that integrates scientific and clinical foundations to highlight translational research. This book serves as a framework for scientists to conceptualize clinical and translational knowledge on the complexity of disease that is metastatic cancer.

Diagnostic and Interventional Neuroradiology

Diagnostic and Interventional Neuroradiology
Author: Klaus Sartor,G. Albrecht
Publsiher: Thieme
Total Pages: 402
Release: 2002
ISBN 10: 9781588901125
ISBN 13: 1588901122
Language: EN, FR, DE, ES & NL

Diagnostic and Interventional Neuroradiology Book Review:

Neuroradiology is evolving at a pace far quicker than any other specialty. It's important for specialists to have detailed knowledge of the newest advances, including state-of-the-art imaging techniques. In this abundantly illustrated text, you'll find the latest information on diseases, imaging principles, differential diagnosis, treatment strategies, and much more! This book is designed to help you easily apply theoretical concepts to your daily practice. It offers a clear and concise review of the most important neuroradiologic approaches to a variety of disorders. Key points are highlighted throughout the text, providing rapid access to the information you need. Residents and experienced practitioners alike will benefit from the wealth of information this book provides. Key benefits: Up-to-the-minute analysis on the newest imaging techniques Detailed review of the use of MRI to measure brain maturation Extensively illustrated to enhance understanding of difficult concepts Most important information is boxed and shaded for emphasis--ideal for board preparation An indispensable aid in clinical settings, NEURORADIOLOGY is an excellent guide to image interpretation as well as a valuable reference for residents preparing for the boards.

Central Nervous System Metastases in Lung Cancer Patients From Prevention to Diagnosis and Treatment

Central Nervous System Metastases in Lung Cancer Patients  From Prevention to Diagnosis and Treatment
Author: Lizza E.L Hendriks,Deepa S. Subramaniam,Anne-Marie C. Dingemans
Publsiher: Frontiers Media SA
Total Pages: 94
Release: 2019-01-21
ISBN 10: 2889457079
ISBN 13: 9782889457076
Language: EN, FR, DE, ES & NL

Central Nervous System Metastases in Lung Cancer Patients From Prevention to Diagnosis and Treatment Book Review:

Approximately 40% of lung cancer patients will develop central nervous system (CNS) metastases during the course of their disease. Most of these are brain metastases, but up to 10% will develop leptomeningeal metastases. Known risk factors for CNS metastases development are small cell lung cancer (SCLC), adenocarcinoma histology, epidermal growth factor receptor (EGFR) mutant or anaplastic lymphoma kinase (ALK) rearranged lung cancer, advanced nodal status, tumor stage and younger age. CNS metastases can have a negative impact on quality of life (QoL) and overall survival (OS). The proportion of lung cancer patients diagnosed with CNS metastases has increased over the years due to increased use of brain imaging as part of initial cancer staging, advances in imaging techniques and better systemic disease control. Post contrast gadolinium enhanced magnetic resonance imaging (gd-MRI) is preferred, however when this is contra-indicated a contrast enhanced computed tomography (CE-CT) is mentioned as an alternative option. When CNS metastases are diagnosed, local treatment options consist of radiotherapy (stereotactic or whole brain) and surgery. Local treatment can be complicated by symptomatic radiation necrosis for which no high level evidence based treatment exists. Moreover, differential diagnosis with metastasis progression is difficult. Systemic treatment options have expanded over the last years. Until recently, chemotherapy was the only treatment option with a poor penetration in the CNS. Angiogenesis inhibitors are promising in the treatment of primary CNS tumors as well as radiation necrosis but clinical trials of anti-angiogenic agents in NSCLC have largely excluded patients with CNS metastases. Furthermore, research has also focused on methods to prevent development of CNS disease, for example with prophylactic cranial irradiation. Recently, checkpoint inhibitors have become available for NSCLC patients, and tyrosine kinase inhibitors (TKIs) have improved prognosis significantly in those with a druggable driver mutation. Newer TKIs are often designed to have better CNS penetration compared to first-generation TKIs. Despite advances in treatment options CNS metastases remain a problem in lung cancer and cause morbidity and mortality. This Research Topic provides an extensive resource of articles describing advances in CNS metastases management in lung cancer patients, from prevention to diagnosis and treatment.

Neurologic Complications of Cancer

Neurologic Complications of Cancer
Author: Lisa M. DeAngelis,Jerome B. Posner
Publsiher: OUP USA
Total Pages: 634
Release: 2009
ISBN 10: 0195366743
ISBN 13: 9780195366747
Language: EN, FR, DE, ES & NL

Neurologic Complications of Cancer Book Review:

The final section addresses several nonmetastatic complications of cancer and includes sections on vascular disease, infections, metabolic and nutritional disorders, side effects of chemotherapy and radiation, and other diagnostic and therapeutic procedures and concludes with a discussion on paraneoplastic syndromes."

New Approaches to the Management of Primary and Secondary CNS Tumors

New Approaches to the Management of Primary and Secondary CNS Tumors
Author: Anonim
Publsiher: Unknown
Total Pages: 329
Release: 19??
ISBN 10: 9789535130529
ISBN 13: 9535130528
Language: EN, FR, DE, ES & NL

New Approaches to the Management of Primary and Secondary CNS Tumors Book Review:

Leksell Radiosurgery

Leksell Radiosurgery
Author: A. Niranjan,L.D. Lunsford,H. Kano
Publsiher: Karger Medical and Scientific Publishers
Total Pages: 322
Release: 2019-05-20
ISBN 10: 331806422X
ISBN 13: 9783318064223
Language: EN, FR, DE, ES & NL

Leksell Radiosurgery Book Review:

Since its introduction 52 years ago, Leksell radiosurgery has become a widely applied technique for the management of a diverse group of vascular, neoplastic, and functional disorders. This publication presents an update on state-of-the-art radiosurgery technology, including outcomes, by the pioneers in the field. Experts have contributed chapters on various topics. They provide a history of the development of Leksell Gamma Knife and its evolution from frame-based to the inclusion of mask-based radiosurgery in the latest Gamma Knife model. For beginners, there is valuable information related to imaging, quality assurance, patient care, anesthesia, and regulatory requirements. Advance users will appreciate the summary of the long-term outcome of important indications. Additional chapters on cavernous malformation, orbital, uveal, and ocular disorders clarify the role of radiosurgery. This book is a concise overview for physicians interested in radiosurgery. It will be of great value to neurosurgeons, radiation oncologists, and medical physicists concerned with learning about the indications of radiosurgery.

Current and Future Management of Brain Metastasis

Current and Future Management of Brain Metastasis
Author: D.G. Kim,L.D. Lunsford
Publsiher: Karger Medical and Scientific Publishers
Total Pages: 326
Release: 2012-01-10
ISBN 10: 3805596189
ISBN 13: 9783805596183
Language: EN, FR, DE, ES & NL

Current and Future Management of Brain Metastasis Book Review:

Recent strategies combining multiple modalities have opened up a whole new field of brain metastasis management focusing on disease control. The management of brain metastasis in modern times is no longer confined to palliation but seeks preservation of life quality and not only prolonged survival. Up-to-date guidelines and the main aspects of brain metastasis management as well as practical points on how to deal with difficult situations in daily clinical practice are presented. Epidemiology and biology and various effective treatment methods such as surgery, radiosurgery, radiation therapy and chemotherapy are well explained. Each chapter encompasses extensive reviews and presents broad perspectives on specific topics by the most renowned personages who have continuously shown their excellence in this rapidly progressing field.This book contains the most current information on the understanding of brain metastasis management. It is valuable reading for neurosurgeons, neuro-oncologists and radiation oncologists who are searching for the best all-round treatment for their patients.

Brain Tumor Imaging

Brain Tumor Imaging
Author: Elke Hattingen,Ulrich Pilatus
Publsiher: Springer
Total Pages: 161
Release: 2015-09-02
ISBN 10: 3642450407
ISBN 13: 9783642450402
Language: EN, FR, DE, ES & NL

Brain Tumor Imaging Book Review:

This book describes the basics, the challenges and the limitations of state of the art brain tumor imaging and examines in detail its impact on diagnosis and treatment monitoring. It opens with an introduction to the clinically relevant physical principles of brain imaging. Since MR methodology plays a crucial role in brain imaging, the fundamental aspects of MR spectroscopy, MR perfusion and diffusion-weighted MR methods are described, focusing on the specific demands of brain tumor imaging. The potential and the limits of new imaging methodology are carefully addressed and compared to conventional MR imaging. In the main part of the book, the most important imaging criteria for the differential diagnosis of solid and necrotic brain tumors are delineated and illustrated in examples. A closing section is devoted to the use of MR methods for the monitoring of brain tumor therapy. The book is intended for radiologists, neurologists, neurosurgeons, oncologists and other scientists in the biomedical field with an interest in neuro-oncology.

Fast Facts Brain Tumors

Fast Facts  Brain Tumors
Author: Lauren E. Abrey,Warren P. Mason
Publsiher: Karger Medical and Scientific Publishers
Total Pages: 144
Release: 2011-01-01
ISBN 10: 1905832877
ISBN 13: 9781905832873
Language: EN, FR, DE, ES & NL

Fast Facts Brain Tumors Book Review:

Despite the availability of many effective treatments, there remains a therapeutic nihilism associated with brain tumors. This highly readable second edition of 'Fast Facts: Brain Tumors' challenges this view, starting from the premise that patients with brain tumors can truly benefit from a thoughtful multidisciplinary approach. This comprehensive handbook covers all the salient features of the various brain tumors and treatment modalities in a way that will be useful to the practicing clinician. • Advances in radiology and pathology that have led to more precise and detailed diagnoses • Developments in molecular biology and imaging techniques that have improved available diagnostic modalities • New neurosurgical techniques that have enabled operations on tumors that were previously considered inoperable • Novel delivery systems that allow various treatments to reach tumors that are otherwise protected by the blood-brain barrier. This fully updated edition of 'Fast Facts: Brain Tumors' bridges the gap between primary care providers - whose role is pivotal in tumor detection and subsequent patient care - and first-level specialists such as general neurologists and neurosurgeons. Its key message is that selection of the best initial approach for an individual patient will result in the best overall outcome, both in terms of survival and quality of life. 'Fast Facts: Brain Tumors' is specifically for the primary care physician whose role is pivotal in tumor detection and subsequent patient care. Contents: • Classification and epidemiology • Diagnosis • Treatment • Brain metastases • Gliomas • Meningiomas • Neuronal tumors • Pineal region tumors • Skull base tumors • Primary central nervous system lymphoma • Brain tumor syndromes and tumor-like cysts • Geriatric neuro-oncology • Useful resources