Bioreactors

Bioreactors
Author: Carl-Fredrik Mandenius
Publsiher: John Wiley & Sons
Total Pages: 520
Release: 2016-05-16
ISBN 10: 3527337687
ISBN 13: 9783527337682
Language: EN, FR, DE, ES & NL

Bioreactors Book Review:

In this expert handbook both the topics and contributors are selected so as to provide an authoritative view of possible applications for this new technology. The result is an up-to-date survey of current challenges and opportunities in the design and operation of bioreactors for high-value products in the biomedical and chemical industries. Combining theory and practice, the authors explain such leading-edge technologies as single-use bioreactors, bioreactor simulators, and soft sensor monitoring, and discuss novel applications, such as stem cell production, process development, and multi-product reactors, using case studies from academia as well as from industry. A final section addresses the latest trends, including culture media design and systems biotechnology, which are expected to have an increasing impact on bioreactor design. With its focus on cutting-edge technologies and discussions of future developments, this handbook will remain an invaluable reference for many years to come.

Bioreactors

Bioreactors
Author: Goutam Saha,Alok Barua,Satyabroto Sinha
Publsiher: CRC Press
Total Pages: 136
Release: 2017-12-01
ISBN 10: 1498736025
ISBN 13: 9781498736022
Language: EN, FR, DE, ES & NL

Bioreactors Book Review:

Bioreactors: Animal Cell Culture Control for Bioprocess Engineering presents the design, fabrication, and control of a new type of bioreactor meant especially for animal cell line culture. The new bioreactor, called the "see-saw bioreactor," is ideal for the growth of cells with a sensitive membrane. The see-saw bioreactor derives its name from its principle of operation in which liquid columns in either limb of the reactor alternately go up and down. The working volume of the reactor is small, to within 15 L. However, it can easily be scaled up for large production in volume of cell mass in the drug and pharmaceutical industries. The authors describe the principle of operation of the see-saw bioreactor and how to automatically control the bioprocess. They discuss different control strategies as well as the thorough experimental research they conducted on this prototype bioreactor in which they applied a time delay control for yield maximization. To give you a complete understanding of the design and development of the see-saw bioreactor, the authors cover the mathematical model they use to describe the kinetics of fermentation, the genetic algorithms used for deriving the optimal time trajectories of the bioprocess variables, and the corresponding control inputs for maximizing the product yield. One chapter is devoted to the application of time delay control. Following a description of the bioreactor’s working setup in the laboratory, the authors sum up their investigation and define the future scope of work in terms of design, control, and software sensors.

Bioreactors for Tissue Engineering

Bioreactors for Tissue Engineering
Author: Julian Chaudhuri,Mohamed Al-Rubeai
Publsiher: Springer Science & Business Media
Total Pages: 376
Release: 2006-01-16
ISBN 10: 1402037414
ISBN 13: 9781402037412
Language: EN, FR, DE, ES & NL

Bioreactors for Tissue Engineering Book Review:

For the first time in a single volume, the design, characterisation and operation of the bioreactor system in which the tissue is grown is detailed. Bioreactors for Tissue Engineering presents an overall picture of the current state of knowledge in the engineering of bioreactors for several tissue types (bone, cartilage, vascular), addresses the issue of mechanical conditioning of the tissue, and describes the use of techniques such as MRI for monitoring tissue growth. This unique volume is dedicated to the fundamentals and application of bioreactor technology to tissue engineering products. Not only will it appeal to graduate students and experienced researchers in tissue engineering and regenerative medicine, but also to tissue engineers and culture technologists, academic and industrial chemical engineers, biochemical engineers and cell biologists who wish to understand the criteria used to design and develop novel systems for tissue growth in vitro.

Bioreactors in Biotechnology

Bioreactors in Biotechnology
Author: Alan H. Scragg
Publsiher: Ellis Horwood Limited
Total Pages: 330
Release: 1991
ISBN 10:
ISBN 13: UOM:39015024793948
Language: EN, FR, DE, ES & NL

Bioreactors in Biotechnology Book Review:

Discusses many aspects of bioreactor use and design in biotechnology. There is coverage of conventional and airlift bioreactor design, instrumentation, control and simulation of bioreactor runs, bioreactors for plant and animal culture and a descriptions of experiments.

Bioreactors

Bioreactors
Author: Lakhveer Singh,Abu Yousuf,Durga Madhab Mahapatra
Publsiher: Academic Press
Total Pages: 368
Release: 2020-04
ISBN 10: 0128212640
ISBN 13: 9780128212646
Language: EN, FR, DE, ES & NL

Bioreactors Book Review:

Bioreactors: Sustainable Design and Industrial Applications in Mitigation of GHG Emissions presents and compares the foundational concepts, state-of-the-art design and fabrication of bioreactors. Solidly based on theoretical fundamentals, the book examines various aspects of the commercially available bioreactors, such as construction and fabrication, design, modeling and simulation, development, operation, maintenance, management and target applications for biofuels production and bio-waste management. Emerging issues in commercial feasibility are explored, constraints and pathways for upscaling, and techno-economic assessment are also covered. This book provides researchers and engineers in the biofuels and waste management sectors a clear, at-a-glance understanding of the actual potential of different advanced bioreactors for their requirements. It is a must-have reference for better-informed decisions when selecting the appropriate technology models for sustainable systems development and commercialization.

Bioreactors Process and Analysis

Bioreactors  Process and Analysis
Author: Tapobrata Panda
Publsiher: Tata McGraw-Hill Education
Total Pages: 491
Release: 2011
ISBN 10: 9780070704244
ISBN 13: 0070704244
Language: EN, FR, DE, ES & NL

Bioreactors Process and Analysis Book Review:

6. Bioreactor modeling -- Model - what is it? -- Definition of lumped and distributed parameter models -- Introduction to a few terminologies and theorems -- Modeling principles -- Steps in modeling -- Fundamental laws used in process modeling -- First-order systems -- Second-order systems -- Complexity of the model -- Parameter sensitivity -- Exercises -- References -- Appendix 6 -- 7. Transport processes in bioreactors -- Introduction -- Heat transfer -- Other parameters influencing transfer operations -- Exercises -- References -- 8. Controls in bioreactors -- Introduction -- Control tasks in a bioreactor system -- Instrumentation to control a bioreactor -- Controlled variables and measurement devices -- Procedure for design of efficient control systems -- Conventional control techniques -- Advanced control techniques -- Consistency checks on measurements -- Adaptive online optimizing control of bioreactor system -- Exercises -- References -- Appendix 8 -- 9. Case studies -- Introduction -- Design of packed bed bioreactor -- Airlift bioreactors -- Hollow fiber bioreactor (HFBR) -- Plant cell bioreactor -- Design of bioreactors for solid state fermentation (SSF) -- Mammalian cell bioreactor design -- Exercises -- References -- Appendix 9 -- 10. Application of computational fluid dynamics in bioreactor analysis and design -- Introduction -- Fluid dynamic modeling -- Simulation -- Exercises -- References -- Appendix 10 -- 11. Scale-up of bioreactors -- Introduction -- Additional scale-up problems in bioreactors -- Criteria of scale-up -- Similarity criteria -- Scale-up methods -- Generalized approaches to scale-up in combination of methods -- Examples -- Exercises -- References -- 12. Mechanical aspects of bioreactor design -- Introduction -- Requirements for construction of a bioreactor -- Guidelines for bioreactor design -- Bioreactor vessels -- Agitator assembly -- Exercises -- References -- Appendix 12

Disposable Bioreactors

Disposable Bioreactors
Author: Regine Eibl,Dieter Eibl
Publsiher: Springer Science & Business Media
Total Pages: 226
Release: 2009-11-27
ISBN 10: 3642018718
ISBN 13: 9783642018718
Language: EN, FR, DE, ES & NL

Disposable Bioreactors Book Review:

Over the past five years, the immense financial pressure on the development and manufacturing of biopharmaceuticals has resulted in the increasing use and acce- ance of disposables, which are discarded after harvest and therefore intended only for single use. In fact, such disposables are implemented in all the main bioprocess production stages today and an even higher growth than those in the biopharmac- tical market is predicted (reaching double figures). Alongside disposable filter capsules, membrane chromatography units, tubing, connectors, flexible containers processing or containing fluids, freezer systems, mixers and pumps, and fully c- trolled disposable bioreactors of up to 2,000 L culture volume are already available on the market. Numerous studies highlight the advantages of disposable bioreactors and reveal their potential for simple, safe and fast seed inoculum production, process devel- ment and small as well as middle volume production (e.g. bioactive substances, viruses for vaccines and gene therapies etc.). They suggest that such disposable bioreactors (typically characterized by the cultivation chamber or bag from plastic materials) may be advantageous for plant, animal and microbial cells. Running industrial activities such as CFD-modelling, development of single-use process monitoring and control technology, and standardized film formulations are attempting to resolve the limitations of the current disposable bioreactors. These achievements, along with substantial improvements in product yield, will reduce the use of stainless steel in the biomanufacturing facilities of the future.

On line Estimation and Adaptive Control of Bioreactors

On line Estimation and Adaptive Control of Bioreactors
Author: G. Bastin
Publsiher: Elsevier
Total Pages: 394
Release: 2013-10-22
ISBN 10: 1483290980
ISBN 13: 9781483290980
Language: EN, FR, DE, ES & NL

On line Estimation and Adaptive Control of Bioreactors Book Review:

This book deals with monitoring and control of biotechnological processes. Different methods are proposed which are based on the nonlinear structure of the process and do not require any a priori knowledge of the fermentation parameters. The theoretical stability and convergence properties of the proposed algorithms are analysed and their performances are illustrated by simulation results and, in many instances, by real life experiments. The concept of software sensors is introduced; these are algorithms based on the nonlinear model of the process and designed for on-line estimation of the biological variables and/or the fermentation parameters. In order to deal with process nonstationarities and parameter uncertainties, reference is made to adaptive estimation and control techniques. The book is the result of an intensive joint research effort by the authors during the last decade. It is intended as a graduate level text for students of bioengineering as well as a reference text for scientists and engineers involved in the design and optimization of bioprocesses.

Animal Cell Bioreactors

Animal Cell Bioreactors
Author: Chester S. Ho
Publsiher: Butterworth-Heinemann
Total Pages: 512
Release: 2013-10-22
ISBN 10: 1483289478
ISBN 13: 9781483289472
Language: EN, FR, DE, ES & NL

Animal Cell Bioreactors Book Review:

Animal Cell Bioreactors provides an introduction to the underlying principles and strategies in the in vitro cell culture biotechnology. It addresses engineering aspects such as mass transfer, instrumentation, and control ensuring successful design and operation of animal cell bioreactors. The goal is to provide a comprehensive analysis and review in the advancement of the bioreactor systems for large-scale animal cell cultures. The book is organized into four parts. Part I traces the historical development of animal cell biotechnology. It presents examples of work in progress that seeks to make animal cell biotechnology processes as productive on a cost per unit of product basis as that achieved by other microbial systems. Part II includes chapters dealing with the implications of cell biology in animal cell biotechnology; protein-bound oligosaccharides and their structures; the development of serum-free media and its use in the production of biologically active substances; and the metabolism of mammalian cells. Part III focuses on animal cell cultivation, covering topics such as the fixed bed immobilized culture; three-dimensional microcarriers; and hydrodynamic phenomena in microcarrier cultures. Part IV discusses the design, operation, and control of animal cell bioreactors.

Solid State Fermentation Bioreactors

Solid State Fermentation Bioreactors
Author: David A. Mitchell,Nadia Krieger,Marin Berovic
Publsiher: Springer Science & Business Media
Total Pages: 448
Release: 2006-08-02
ISBN 10: 3540312862
ISBN 13: 9783540312864
Language: EN, FR, DE, ES & NL

Solid State Fermentation Bioreactors Book Review:

This concise professional reference provides a fundamental framework for the design and operation of solid-state fermentation bioreactors, enabling researchers currently working at laboratory scale to scale up their processes. The authors survey bioreactor types in common use, and describe in depth how to plan a project, and model heat transfer phenomena. The book includes case studies, and a review of practical issues involved in bioreactor performance.

Bioreactors

Bioreactors
Author: Luigi Salvay
Publsiher: Unknown
Total Pages: 304
Release: 2017-02
ISBN 10: 9781681176956
ISBN 13: 1681176955
Language: EN, FR, DE, ES & NL

Bioreactors Book Review:

Airlift Bioreactors

Airlift Bioreactors
Author: M. Y. Chisti
Publsiher: Springer
Total Pages: 345
Release: 1989-02-28
ISBN 10:
ISBN 13: UOM:39015048303500
Language: EN, FR, DE, ES & NL

Airlift Bioreactors Book Review:

The MBR Book

The MBR Book
Author: Simon Judd
Publsiher: Elsevier
Total Pages: 536
Release: 2010-11-26
ISBN 10: 9780080967677
ISBN 13: 0080967671
Language: EN, FR, DE, ES & NL

The MBR Book Book Review:

The MBR Book covers all essential aspects of membrane bioreactors in water and wastewater treatment, including the working principles of MBR technologies. The book aims to separate science from engineering, in an attempt to avoid confusion and to help readers understand the ideas of MBR. The text is divided into five chapters; the membrane and biological aspects are discussed in chapter 2 along with scientific studies. The third chapter covers the design, operation, and maintenance of MBR, including cost modeling and cost benefit analysis. Chapters 4 and 5 cover the commercial MBR products and their applications for water and wastewater treatment, respectively. The text features industrial case studies, along with useful appendices of commercial and international membrane organizations. The book serves as a a primary reference for chemical, environmental, and process engineers, as well as environmental researchers, natural resources researchers, filtration specialists, water company managers, and consultants. Membrane Bioreactors are a major growth area in the water and waste water treatment industries Internationally-known author, one of the leading senior experts in MBR research Principles and practice, backed by industrial case studies

Production of Potato Microtubers in Bioreactors

Production of Potato Microtubers in Bioreactors
Author: Wan-Chin Yu
Publsiher: Unknown
Total Pages: 296
Release: 1998
ISBN 10:
ISBN 13: WISC:89066551342
Language: EN, FR, DE, ES & NL

Production of Potato Microtubers in Bioreactors Book Review:

Reductive Dechlorination of Chlorinated Phenols in Anaerobic Upflow Bioreactors

Reductive Dechlorination of Chlorinated Phenols in Anaerobic Upflow Bioreactors
Author: Mary Luise Krumme
Publsiher: Unknown
Total Pages: 258
Release: 1986
ISBN 10:
ISBN 13: MSU:31293031450871
Language: EN, FR, DE, ES & NL

Reductive Dechlorination of Chlorinated Phenols in Anaerobic Upflow Bioreactors Book Review:

Resealed erythrocytes as carriers and bioreactors

Resealed erythrocytes as carriers and bioreactors
Author: Ralph Green,John R. DeLoach
Publsiher: Pergamon
Total Pages: 252
Release: 1991
ISBN 10: 9780080411569
ISBN 13: 0080411568
Language: EN, FR, DE, ES & NL

Resealed erythrocytes as carriers and bioreactors Book Review:

Bioreactors

Bioreactors
Author: Paolo G. Antolli,Zhiming Liu
Publsiher: Nova Science Pub Incorporated
Total Pages: 225
Release: 2012
ISBN 10: 9781621001645
ISBN 13: 1621001644
Language: EN, FR, DE, ES & NL

Bioreactors Book Review:

Book Description: Bioreactors are the heart of many biotechnological systems that are used for agriculture, environmental, industrial and medical applications. This book presents the design, properties and applications of bioreactors. Topics discussed include bioreactors for microalgae; application of different types of bioreactors in bioprocesses; airlift bioreactors and its application in fermentation and wastewater treatment; development and deployment of a bioreactor for the removal of sulfate and manganese from circumneutral coal mine drainage and kinetic coefficients and factors affecting aeration efficiency as design parameters of MBR. (Imprint: Nova)

The Use of Dinoflagellates to Characterize Cell Stimulation in Bioreactors

The Use of Dinoflagellates to Characterize Cell Stimulation in Bioreactors
Author: Antony Kuang-Shih Chen
Publsiher: Unknown
Total Pages: 114
Release: 2002
ISBN 10:
ISBN 13: UCSD:31822009314170
Language: EN, FR, DE, ES & NL

The Use of Dinoflagellates to Characterize Cell Stimulation in Bioreactors Book Review:

Immobilization of Bacterial and Yeast Cells in Hollow fiber Membrane Bioreactors

Immobilization of Bacterial and Yeast Cells in Hollow fiber Membrane Bioreactors
Author: Douglas Scott Inloes
Publsiher: Unknown
Total Pages: 368
Release: 1982
ISBN 10:
ISBN 13: STANFORD:36105031927754
Language: EN, FR, DE, ES & NL

Immobilization of Bacterial and Yeast Cells in Hollow fiber Membrane Bioreactors Book Review:

Eco Engineered Bioreactors

Eco Engineered Bioreactors
Author: James Higgins,Al Mattes,William Stiebel,Brent Wootton
Publsiher: CRC Press
Total Pages: 385
Release: 2017-11-22
ISBN 10: 1351681117
ISBN 13: 9781351681117
Language: EN, FR, DE, ES & NL

Eco Engineered Bioreactors Book Review:

This book provides a comprehensive understanding of a highly innovative method of natural wastewater treatment using advanced in-groundbioreactors called Eco-Engineered Bioreactors (EEBs), and traces their evolution from the earliest aerated gravel bed versions once known as Engineered Wetlands (EWs) and now known as BREW Bioreactors (BBRs) all the way to today’s wide slate of aerobic and anaerobic varieties. Treatment using EEBs involves passing wastewaters through excavated basins in which they contact fixed films of microbial consortia on permeable substrate media. Written from the perspective of ecological engineers designing EEBs, this guide covers updated information on the state-of-the-art for EEBs, covering their morphologies, testing methods, designs, operations, and microbiology.