Biopharmaceutics and Pharmacokinetics Considerations

Biopharmaceutics and Pharmacokinetics Considerations
Author: Anonim
Publsiher: Academic Press
Total Pages: 575
Release: 2020-12-15
ISBN 10: 9780128144251
ISBN 13: 0128144254
Language: EN, FR, DE, ES & NL

Biopharmaceutics and Pharmacokinetics Considerations Book Review:

Biopharmaceutics and Pharmacokinetics Considerations examines the history of biopharmaceutics and pharmacokinetics. The book provides a biopharmaceutics and pharmacokinetics approach to addressing issues in formulation development and ethical considerations in handling animals. Written by experts in the field, this volume within the Advances in Pharmaceutical Product Development and Research series deepens understanding of biopharmaceutics and pharmacokinetics within drug discovery and drug development. Each chapter delves into a particular aspect of this fundamental field to cover the principles, methodologies and technologies employed by pharmaceutical scientists, researchers and pharmaceutical industries to study the chemical and physical properties of drugs and the biological effects they produce. Examines the most recent developments in biopharmaceutics and pharmacokinetics for pharmaceutical sciences Covers the principles, methodologies and technologies of biopharmaceutics and pharmacokinetics Focuses on the pharmaceutical sciences, but also encompasses aspects of toxicology, neuroscience, environmental sciences and nanotechnology

Biopharmaceutics and clinical pharmacokinetics

Biopharmaceutics and clinical pharmacokinetics
Author: Anonim
Publsiher: Anonim
Total Pages: 329
Release: 1977
ISBN 10:
ISBN 13: UCAL:B5040156
Language: EN, FR, DE, ES & NL

Biopharmaceutics and clinical pharmacokinetics Book Review:

Biopharmaceutics and Clinical Pharmacokinetics

Biopharmaceutics and Clinical Pharmacokinetics
Author: Milo Gibaldi
Publsiher: Lippincott Williams & Wilkins
Total Pages: 406
Release: 1991
ISBN 10:
ISBN 13: UOM:39015018883739
Language: EN, FR, DE, ES & NL

Biopharmaceutics and Clinical Pharmacokinetics Book Review:

This updated introduction to the clinical applications of pharmacokinetics looks at gastrointestinal absorption, prolonged release medication, and drug disposition. The effects of disease, weight, age, sex and genetic factors on pharmacokinetic variability and drug response are detailed. Bioequivalence and regulatory considerations for generic drug.

Biopharmaceutics Applications in Drug Development

Biopharmaceutics Applications in Drug Development
Author: Rajesh Krishna,Lawrence Yu
Publsiher: Springer Science & Business Media
Total Pages: 396
Release: 2007-09-20
ISBN 10: 038772379X
ISBN 13: 9780387723792
Language: EN, FR, DE, ES & NL

Biopharmaceutics Applications in Drug Development Book Review:

The highly experienced authors here present readers with step-wise, detail-conscious information to develop quality pharmaceuticals. The book is made up of carefully crafted sections introducing key concepts and advances in the areas of dissolution, BA/BE, BCS, IVIC, and product quality. It provides a specific focus on the integration of regulatory considerations and includes case histories highlighting the biopharmaceutics strategies adopted in development of successful drugs.

Biopharmaceutics Pharmacokinetics

Biopharmaceutics   Pharmacokinetics
Author: Dr. A. R. Paradkar
Publsiher: Pragati Books Pvt. Ltd.
Total Pages: 150
Release: 2008-10-06
ISBN 10: 9788185790374
ISBN 13: 818579037X
Language: EN, FR, DE, ES & NL

Biopharmaceutics Pharmacokinetics Book Review:

Applied Biopharmaceutics and Pharmacokinetics

Applied Biopharmaceutics and Pharmacokinetics
Author: Leon Shargel,Andrew B. C. Yu
Publsiher: McGraw-Hill/Appleton & Lange
Total Pages: 625
Release: 1993
ISBN 10:
ISBN 13: UOM:39015029461012
Language: EN, FR, DE, ES & NL

Applied Biopharmaceutics and Pharmacokinetics Book Review:

The third edition of this introductory text covers the factors which influence the release of the drug from the drug product and how the body handles the drug. A stronger focus has been placed on the basics with clear explanations and illustrated examples. There is also more information on statistics and population pharmacokinetics and new chapters on drug distribution, computer applications, enzyme kinetics and pharmacokinetics models.

Biopharmaceutics and Clinical Pharmacokinetics

Biopharmaceutics and Clinical Pharmacokinetics
Author: Notari
Publsiher: Routledge
Total Pages: 440
Release: 2017-11-22
ISBN 10: 1351463845
ISBN 13: 9781351463843
Language: EN, FR, DE, ES & NL

Biopharmaceutics and Clinical Pharmacokinetics Book Review:

For a decade and a half, Biopharmaceutics and Clinical Pharmacokinetics has been used in theclassrooms around the world as an introductory textbook on biophannaceutics and phannacokinetics.Now, the new Fourth Edition, Revised and Expanded further enhances the preceding editions'proven features, introducing significant advances in clinical pharmacokinetics, pharmacokineticdesign of drugs and dosage forms, and model-independent analyses.Still usable without prior knowledge of calculus or kinetics, this successfully implemented workbookmaintains a carefully graduated "building block" presentation, incorporating sample problemsand exercises throughout for a thorough understanding of the material.Biopharmaceutics and Clinical Pharmacokinetics features a growth-oriented format that systematicallydevelops and interrelates all subject matter .. . introduces basic theory and fields of application... emphasizes model-independent pharmacokinetic analyses ... presents biopharmaceutical aspectsof product design and evaluation .. . offers a unique approach to teaching dosage regimen design andindividualization . .. and considers structural modification of drug molecules for problems associatedwith pharmacokinetics.As a comprehensive coverage of the basic principles and the recent achievements in the field, noother textbook does as much for students of pharmacy, pharmacology, medicinal chemistry, andmedicine, or for scientists who desire a simple but thorough introduction to theory and application.

Basic Pharmacokinetics

Basic Pharmacokinetics
Author: Mohsen A. Hedaya
Publsiher: CRC Press
Total Pages: 328
Release: 2007-04-23
ISBN 10: 1420046721
ISBN 13: 9781420046724
Language: EN, FR, DE, ES & NL

Basic Pharmacokinetics Book Review:

This volume is a self-instructional computer-assisted medium for active learning. Indeed, the tutorial materials included in the accompanying compact disk have received an award from the American Association of Colleges of Pharmacy for innovation in teaching. This volume and its companion CD are intended for students and practitioners in the health professions who need to comprehend the concepts and principles related to how the body absorbs, distributes, metabolizes, and excretes drugs. "...The author's reliance on active learning, his use of examples illustrating important pharmacokinetic principles, and particularly the thoughtful simulation tools he has developed make this text and its companion CD an extremely effective and enjoyable introduction to the field of pharmacokinetics." From the Foreword, Ronald J. Sawchuk Minneapolis, Minnesota Pharmacokinetics has become an essential component of all the processes involved in drug development, discovery, and preclinical evaluation, as well as with the clinical use of drugs. While this has led to the development of many highly complex techniques, basic pharmacokinetic concepts remain the backbone of all these new developments. Consequently, a thorough understanding of the basic concepts is essential before one can tackle the more involved and applied areas of pharmacokinetics. Basic Pharmacokinetics consists of two parts: textual printed materials and highly interactive computer-based presentations. Together, these provide a useful combination that makes it easy to grasp basic principles. The computer-based information is presented in a self-instructional format, which introduces concepts, utilizing highly interactive graphical presentations and simulations. It visualizes the interplay between the different pharmacokinetic parameters, observing how the change in one or more of these parameters impacts the drug concentration-time profile in the body. Uniquely and carefully designed, the learning modules in the CD closely support and complement the text, providing the learner with an opportunity to reinforce his or her understanding of the principles presented.

Applications of Pharmacokinetic Principles in Drug Development

Applications of Pharmacokinetic Principles in Drug Development
Author: Rajesh Krishna
Publsiher: Springer Science & Business Media
Total Pages: 550
Release: 2012-12-06
ISBN 10: 1441992162
ISBN 13: 9781441992161
Language: EN, FR, DE, ES & NL

Applications of Pharmacokinetic Principles in Drug Development Book Review:

This volume is an important advancement in the application ofpharmacokinetic (PK) and pharmacodynamic (PO) principles to . drug development. The series of topics presented deal with the application of these tools to everyday decisions that a pharmaceutical scientist encounters. The ability to integrate these topics using PK and PO methods has optimized drug development pathways in the clinic. New technologies in the areas of in vitro assays that are more predictive of human absorption and metabolism and advancement in bioanalytical assays are leading the way to minimize drug failures in later, more expensive clinical development programs. of Pharmacokinetics and pharmacodynamics have become an important component understanding the drug action on the body and is becoming increasingly important in drug labeling due to it's potential for predicting drug behavior in populations that may be difficult to study in adequate numbers during drug development. The ability to correlate drug exposure to effect and model it during the drug development value chain provides valuable insight into optimizing the next steps to derive maximum information from each study. These principles and modeling techniques have resulted in an expanded and integrated view of PK and PO and have led to the expectations that we may be able to optimally design clinical trials and eventually lead us to identifying the optimal therapy for the patient, while minimizing cost and speeding up drug development. There is wide utility for the book both as a text and as a reference.

Applied Biopharmaceutics Pharmacokinetics

Applied Biopharmaceutics   Pharmacokinetics
Author: Leon Shargel,Susanna Wu-Pong,Andrew B. C. Yu
Publsiher: McGraw-Hill Medical Publishing
Total Pages: 892
Release: 2005
ISBN 10:
ISBN 13: UOM:39015059132483
Language: EN, FR, DE, ES & NL

Applied Biopharmaceutics Pharmacokinetics Book Review:

Annotation The primary emphasis of this book is on the application and understanding of concepts. Basic theoretical discussions of the principles of biopharmaceutics and pharmacokinetics are provided, along with illustrative examples and practice problems and solutions to help the student gain skill in practical problem solving.

Applied Biopharmaceutics and Pharmacokinetics

Applied Biopharmaceutics and Pharmacokinetics
Author: Leon Shargel,Andrew B. C. Yu
Publsiher: McGraw-Hill/Appleton & Lange
Total Pages: 625
Release: 1993
ISBN 10:
ISBN 13: UOM:39015029461012
Language: EN, FR, DE, ES & NL

Applied Biopharmaceutics and Pharmacokinetics Book Review:

The third edition of this introductory text covers the factors which influence the release of the drug from the drug product and how the body handles the drug. A stronger focus has been placed on the basics with clear explanations and illustrated examples. There is also more information on statistics and population pharmacokinetics and new chapters on drug distribution, computer applications, enzyme kinetics and pharmacokinetics models.

Applied Biopharmaceutics Pharmacokinetics Fifth Edition

Applied Biopharmaceutics   Pharmacokinetics  Fifth Edition
Author: Leon Shargel,Susanna Wu-Pong,Andrew Yu
Publsiher: McGraw Hill Professional
Total Pages: 892
Release: 2004-09-09
ISBN 10: 0071501878
ISBN 13: 9780071501873
Language: EN, FR, DE, ES & NL

Applied Biopharmaceutics Pharmacokinetics Fifth Edition Book Review:

The most comprehensive text on the practical applications of biopharmaceuticals and pharmacokinetics! 4 STAR DOODY'S REVIEW! "The updated edition provides the reader with a solid foundation in the basic principles of pharmacokinetics and biopharmaceutics. Students will be able to apply the information to their clinical practice and researchers will find this to be a valuable reference. This modestly priced book should be the gold standard for student use."--Doody's Review Service The primary emphasis of this book is on the application and understanding of concepts. Basic theoretical discussions of the principles of biopharmaceutics and pharmacokinetics are provided, along with illustrative examples and practice problems and solutions to help the student gain skill in practical problem solving.

Preclinical Development Handbook

Preclinical Development Handbook
Author: Shayne Cox Gad
Publsiher: John Wiley & Sons
Total Pages: 1352
Release: 2008-03-14
ISBN 10: 0470248475
ISBN 13: 9780470248478
Language: EN, FR, DE, ES & NL

Preclinical Development Handbook Book Review:

A clear, straightforward resource to guide you through preclinical drug development Following this book's step-by-step guidance, you can successfully initiate and complete critical phases of preclinical drug development. The book serves as a basic, comprehensive reference to prioritizing and optimizing leads, dose formulation, ADME, pharmacokinetics, modeling, and regulations. This authoritative, easy-to-use resource covers all the issues that need to be considered and provides detailed instructions for current methods and techniques. Each chapter is written by one or more leading experts in the field. These authors, representing the many disciplines involved in preclinical toxicology screening and testing, give you the tools needed to apply an effective multidisciplinary approach. The editor has carefully reviewed all the chapters to ensure that each one is thorough, accurate, and clear. Among the key topics covered are: * Modeling and informatics in drug design * Bioanalytical chemistry * Absorption of drugs after oral administration * Transporter interactions in the ADME pathway of drugs * Metabolism kinetics * Mechanisms and consequences of drug-drug interactions Each chapter offers a full exploration of problems that may be encountered and their solutions. The authors also set forth the limitations of various methods and techniques used in determining the safety and efficacy of a drug during the preclinical stage. This publication should be readily accessible to all pharmaceutical scientists involved in preclinical testing, enabling them to perform and document preclinical safety tests to meet all FDA requirements before clinical trials may begin.

Applied Biopharmaceutics Pharmacokinetics Seventh Edition

Applied Biopharmaceutics   Pharmacokinetics  Seventh Edition
Author: Leon Shargel,Andrew B. C. Yu
Publsiher: McGraw Hill Professional
Total Pages: 928
Release: 2015-11-22
ISBN 10: 0071829644
ISBN 13: 9780071829649
Language: EN, FR, DE, ES & NL

Applied Biopharmaceutics Pharmacokinetics Seventh Edition Book Review:

The landmark textbook on the theoretical and practical applications of biopharmaceutics and pharmacokinetics—now fully updated. Explains how to detect clinical pharmacokinetic problems and apply basic pharmacokinetic principles to solve them Helps you critically evaluate biopharmaceutic studies involving drug product equivalency and unequivalency Chapters have been revised to reflect the latest clinical perspectives on drug performance, bioavailability, bioequivalence, pharmacokinetics, pharmacodynamics, and drug therapy The field’s leading text for more than three decades, Applied Biopharmaceutics & Pharmacokinetics gets you up to speed on the basics of the discipline like no other resource. Practical problems and clinical examples with discussions are integrated within each chapter to help you apply principles to patient care and drug consultation situations. In addition, outstanding pedagogy, including chapter objectives, chapter summaries, and FAQs, plus additional application questions, identify and focus on key concepts. Written by authors who have both academic and clinical experience, Applied Biopharmaceutics & Pharmacokinetics shows you how to use raw data and formulate the pharmacokinetic models and parameters that best describe the process of drug absorption, distribution, and elimination. The book also helps you work with pharmacokinetic and biopharmaceutic parameters to design and evaluate dosage regimens of drugs. In the seventh edition of this must-have interactive learning tool, most of the chapters are updated to reflect our current understanding of complex issues associated with safe and efficacious drug therapy.

Applied Biopharmaceutics Pharmacokinetics Sixth Edition

Applied Biopharmaceutics   Pharmacokinetics  Sixth Edition
Author: Leon Shargel,Andrew Yu,Susanna Wu-Pong
Publsiher: McGraw Hill Professional
Total Pages: 811
Release: 2012-12-22
ISBN 10: 0071603948
ISBN 13: 9780071603942
Language: EN, FR, DE, ES & NL

Applied Biopharmaceutics Pharmacokinetics Sixth Edition Book Review:

A comprehensive textbook on the theoretical and practical applications of biopharmaceutics and pharmacokinetics The field’s leading text for more than three decades Applied Biopharmaceutics & Pharmacokinetics, Sixth Edition provides you with a basic understanding of the principles of biopharmaceutics and pharmacokinetics and applies these principles to drug product development, drug product performance and drug therapy. The revised and updated sixth edition is unique in teaching basic concepts that relate to understanding the complex issues associated with safe and efficacious drug therapy. Written by authors who have both academic and clinical experience, Applied Biopharmaceutics & Pharmacokinetics will help you to: Understand the basic concepts in biopharmaceutics and pharmacokinetics. Use raw data and derive the pharmacokinetic models and parameters that best describe the process of drug absorption, distribution, and elimination Critically evaluate biopharmaceutic studies involving drug product equivalency and unequivalency Design and evaluate dosage regimens of drugs, using pharmacokinetic and biopharmaceutic parameters Detect potential clinical pharmacokinetic problems and apply basic pharmacokinetic principles to solve them Practical problems and clinical examples with discussions are included in each chapter to help you apply these principles to patient care and drug consultation situations. Chapter Objectives, Chapter Summaries, and Frequently Asked Questions along with additional application questions appear within each chapter to identify and focus on key concepts. Most of the chapters have been revised to reflect our current understanding of drug product performance, bioavailability, bioequivalence, pharmacokinetics, pharmacodynamics, and drug therapy.

Modeling in Biopharmaceutics Pharmacokinetics and Pharmacodynamics

Modeling in Biopharmaceutics  Pharmacokinetics and Pharmacodynamics
Author: Panos Macheras,Athanassios Iliadis
Publsiher: Springer
Total Pages: 483
Release: 2016-03-30
ISBN 10: 3319275984
ISBN 13: 9783319275987
Language: EN, FR, DE, ES & NL

Modeling in Biopharmaceutics Pharmacokinetics and Pharmacodynamics Book Review:

The state of the art in Biopharmaceutics, Pharmacokinetics, and Pharmacodynamics Modeling is presented in this new second edition book. It shows how advanced physical and mathematical methods can expand classical models in order to cover heterogeneous drug-biological processes and therapeutic effects in the body. The book is divided into four parts; the first deals with the fundamental principles of fractals, diffusion and nonlinear dynamics; the second with drug dissolution, release, and absorption; the third with epirical, compartmental, and stochastic pharmacokinetic models, with two new chapters, one on fractional pharmacokinetics and one on bioequivalence; and the fourth mainly with classical and nonclassical aspects of pharmacodynamics. The classical models that have relevance and application to these sciences are also considered throughout. This second edition has new information on reaction limited models of dissolution, non binary biopharmaceutic classification system, time varying models, and interface models. Many examples are used to illustrate the intrinsic complexity of drug administration related phenomena in the human, justifying the use of advanced modeling methods. This book will appeal to graduate students and researchers in pharmacology, pharmaceutical sciences, bioengineering, and physiology. Reviews of the first edition: "This book presents a novel modelling approach to biopharmaceutics, pharmacokinetics and pharmacodynamic phenomena. This state-of-the-art volume will be helpful to students and researchers in pharmacology, bioengineering, and physiology. This book is a must for pharmaceutical researchers to keep up with recent developments in this field." (P. R. Parthasarathy, Zentralblatt MATH, Vol. 1103 (5), 2007) "These authors are the unique (or sole) contributors in this area that are working on these questions and bring a special expertise to the field that is now being recognized as essential to understanding biological system and kinetic/dynamic characteristics in drug development...This text is an essential primer for those who would envision the incorporation of heterogeneous approaches to systems where homogeneous approaches are not sufficient to describe the system." (Robert R. Bies, Journal of Clinical Pharmacology, Vol. 46, 2006)

Frontiers in Drug Design and Discovery

Frontiers in Drug Design and Discovery
Author: Atta-ur- Rahman,Gary W. Caldwell, M. Iqbal Choudhary,Zhengyin Yan
Publsiher: Bentham Science Publishers
Total Pages: 457
Release: 2009
ISBN 10: 1608052028
ISBN 13: 9781608052028
Language: EN, FR, DE, ES & NL

Frontiers in Drug Design and Discovery Book Review:

"Frontiers in Drug Design and Discovery" is an Ebook series devoted to publishing the latest and the most important advances in drug design and discovery. Eminent scientists write contributions on all areas of rational drug design and drug discovery inclu

Clinical Pharmacokinetics

Clinical Pharmacokinetics
Author: John E. Murphy
Publsiher: ASHP
Total Pages: 434
Release: 2011-10-01
ISBN 10: 9781585283477
ISBN 13: 1585283479
Language: EN, FR, DE, ES & NL

Clinical Pharmacokinetics Book Review:

In the complex field of pharmacokinetics, one reference guide has an identity all its own: Clinical Pharmacokinetics. Now the fully updated 5th edition brings to experienced practitioners and students alike the fresh information they need most: · Content organized for fast reference to specific drugs · The latest on dosing in obese and overweight patients · Dosing considerations for neonatal, pediatric and geriatric patients · A look at protein binding and its implications · Population values for a variety of drugs to initiate dosing · Drug dosing in renal disease and creatinine clearance estimation A Distinctively Straightforward Guide is Now Even Better The 5th Edition of Clinical Pharmacokinetics is completely revised and updated, making a handy clinical guide even easier to use than ever. · Reorganized content features two sections: Basic Concepts and Special Populations and Specific Drugs and Drug Classes · Sections on special populations, including Dosing in Overweight and Obese Patients, have been conveniently grouped together · Comprehensive introduction covers means, measurements and monitoring · Also conveniently placed up front” a glossary of pharmacokinetics basics and commonly used equations

Introduction to Biopharmaceutics

Introduction to Biopharmaceutics
Author: Milo Gibaldi
Publsiher: Anonim
Total Pages: 80
Release: 1971
ISBN 10:
ISBN 13: UOM:39015072267951
Language: EN, FR, DE, ES & NL

Introduction to Biopharmaceutics Book Review:

Biotechnology and Biopharmaceuticals

Biotechnology and Biopharmaceuticals
Author: Anonim
Publsiher: John Wiley & Sons
Total Pages: 744
Release: 2013-09-19
ISBN 10: 1118659988
ISBN 13: 9781118659984
Language: EN, FR, DE, ES & NL

Biotechnology and Biopharmaceuticals Book Review:

Biotechnology and Biopharmaceuticals: Transforming Proteins and Genes into Drugs, Second Edition addresses the pivotal issues relating to translational science, including preclinical and clinical drug development, regulatory science, pharmaco-economics and cost-effectiveness considerations. The new edition also provides an update on new proteins and genetic medicines, the translational and integrated sciences that continue to fuel the innovations in medicine, as well as the new areas of therapeutic development including cancer vaccines, stem cell therapeutics, and cell-based therapies.