Biomarkers of Hip Implant Function

Biomarkers of Hip Implant Function
Author: Ilona Swiatkowska
Publsiher: Academic Press
Total Pages: 200
Release: 2021-06-15
ISBN 10: 9780128215968
ISBN 13: 0128215968
Language: EN, FR, DE, ES & NL

Biomarkers of Hip Implant Function Book Review:

Biomarkers of Hip Implant Function: Diagnostic Modalities to Prevent Chronic Periprosthetic Joint Infection and Implant Failure brings together established and potential new biomarkers, critically evaluating their clinical usefulness based on recent evidence. Researchers will benefit from a comprehensive view of the topic to identify underexplored areas. Orthopedic surgeons and general practitioners will use the book to monitor implant performance and facilitate management of their patients. Additionally, the work will benefit engineers and joint implant manufacturers to guide improvements in design. This book will also be of interest to regulators and policymakers by helping them update their guidelines on follow-ups for hip implant recipients. Nearly all orthopedic surgeons have implanted a cobalt-chromium hip and most general practitioners have at least one patient with cobalt-chromium implant on their books. The recent worldwide controversy surrounding metal-on-metal hips means that advice on how to manage patients with these implants is of great interest to these professionals. Hence, this book is a welcomed addition to the conversation. Covers all candidate biomarkers of hip implant wear and toxicity in a single source Summarizes recent research into blood titanium levels associated with well-functioning and malfunctioning hip implants to aid implant revision decisions Contains essential clinical cases and tables to illustrate points

Prosthetic Joint Infections

Prosthetic Joint Infections
Author: Trisha Peel
Publsiher: Springer
Total Pages: 263
Release: 2017-11-28
ISBN 10: 3319652508
ISBN 13: 9783319652504
Language: EN, FR, DE, ES & NL

Prosthetic Joint Infections Book Review:

This book outlines the most updated clinical guidelines that are vital for the prevention infections and care of patients with joint infections following a replacement surgery, one of the highest volume medical interventions globally. Sections address the diagnosis, management approaches and prevention of prosthetic joint infections. Written by experts in the field, this text provides a brief overview of the literature and current recommendations in each of the specified areas. Given the rapidly evolving state-of-play in this clinical area, this compendium grows increasingly important to clinicians in their management decisions. Prosthetic Joint Infections is a valuable resource for infectious disease specialists, epidemiologists, surgeons, and orthopedic specialists who may work with patients with prosthetic joint infections.

Volume 47 Issue 1 An Issue of Orthopedic Clinics

Volume 47  Issue 1  An Issue of Orthopedic Clinics
Author: Asif M. Ilyas,Shital N. Parikh,Saqib Rehman,Giles R Scuderi,Felasfa M. Wodajo
Publsiher: Elsevier Health Sciences
Total Pages: 299
Release: 2016-01-19
ISBN 10: 0323414613
ISBN 13: 9780323414616
Language: EN, FR, DE, ES & NL

Volume 47 Issue 1 An Issue of Orthopedic Clinics Book Review:

Each issue of Orthopedic Clinics offers clinical review articles on the most cutting edge technologies, techniques, and more in the field. Major topic areas include: adult reconstruction, upper extremity, pediatrics, trauma, oncology, hand, foot & ankle, and sports medicine.

Advances in Intelligent Data Analysis XV

Advances in Intelligent Data Analysis XV
Author: Henrik Boström,Arno Knobbe,Carlos Soares,Panagiotis Papapetrou
Publsiher: Springer
Total Pages: 404
Release: 2016-09-23
ISBN 10: 3319463497
ISBN 13: 9783319463490
Language: EN, FR, DE, ES & NL

Advances in Intelligent Data Analysis XV Book Review:

This book constitutes the refereed conference proceedings of the 15th International Conference on Intelligent Data Analysis, which was held in October 2016 in Stockholm, Sweden. The 36 revised full papers presented were carefully reviewed and selected from 75 submissions. The traditional focus of the IDA symposium series is on end-to-end intelligent support for data analysis. The symposium aims to provide a forum for inspiring research contributions that might be considered preliminary in other leading conferences and journals, but that have a potentially dramatic impact.

Biomarkers in Toxicology

Biomarkers in Toxicology
Author: Ramesh C. Gupta
Publsiher: Academic Press
Total Pages: 1246
Release: 2019-02-13
ISBN 10: 0128146567
ISBN 13: 9780128146569
Language: EN, FR, DE, ES & NL

Biomarkers in Toxicology Book Review:

Biomarkers in Toxicology, Second Edition, is a timely and comprehensive reference dedicated to all aspects of biomarkers that relate to chemical exposure and their effects on biological systems. This revised and completely updated edition includes both vertebrate and non-vertebrate species models for toxicological testing and the development of biomarkers. Divided into several key sections, this reference volume contains new chapters devoted to topics in microplastics, neuroimmunotoxicity and nutraceuticals, along with a look at the latest cutting-edge technologies used to detect biomarkers. Each chapter contains several references to current literature and important resources for further reading. Given this comprehensive treatment, this book is an essential reference for anyone interested in biomarkers across the scientific and biomedical fields. Evaluates the expansive literature, providing one resource covering all aspects of toxicology biomarkers Includes completely revised chapters, along with additional chapters on the newest developments in the field Identifies and discusses the most sensitive, accurate, unique and validated biomarkers used as indicators of exposure Covers special topics and applications of biomarkers, including chapters on molecular toxicology biomarkers, biomarker analysis for nanotoxicology, development of biomarkers for drug efficacy evaluation, and much more

Examining the Use of Biomarkers in Establishing the Presence and Severity of Impairments

Examining the Use of Biomarkers in Establishing the Presence and Severity of Impairments
Author: National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Care Services
Publsiher: National Academies Press
Total Pages: 84
Release: 2020-12-15
ISBN 10: 0309682665
ISBN 13: 9780309682664
Language: EN, FR, DE, ES & NL

Examining the Use of Biomarkers in Establishing the Presence and Severity of Impairments Book Review:

As part of the overall disability determination process, the Social Security Administration uses a step-by-step approach to understand how severe an individual's condition is and whether it meets program criteria for disability. The use of various types of biomarkers has been suggested as a way to strengthen the amount and quality of objective evidence available to the review process. At the request of the Social Security Administration, the National Academies of Sciences, Engineering, and Medicine's Board on Health Care Services organized a virtual workshop on July 21, 2020, titled The State of the Science of the Use of Biomarkers to Establish the Presence and Severity of Impairments. Workshop discussions focused on the current and potential uses for biomarkers; explored legal and ethical implications associated with biomarker use in clinical decision making; and considered the possible uses of nongenetic biomarkers as tools for the diagnosis or prognosis of the severity of specific physical and mental impairments. This publication summarizes the presentations and discussion of the workshop.

Osteoarthritis Biomarkers and Treatments

Osteoarthritis Biomarkers and Treatments
Author: Anonim
Publsiher: BoD – Books on Demand
Total Pages: 114
Release: 2019-03-27
ISBN 10: 1789857376
ISBN 13: 9781789857375
Language: EN, FR, DE, ES & NL

Osteoarthritis Biomarkers and Treatments Book Review:

This book presents exclusive and comprehensive insight into the detailed molecular mechanisms of osteoarthritis (OA) initiation, progression and current advancements in the field. Inputs from clinician scientists, research and expertise offer a complete explanation of the current understanding of the pathogenesis of OA and practice in imaging and treatments strategies. Contributions from leading scientists provide a detailed introduction in the use of biomarkers in clinical research as well as in clinical practice and OA diagnosis. This book further discusses the potential of regenerative therapies and recent advances in cardiovascular and functional capacity on patients with OA.

Novel Biomarkers for Heart Disease

Novel Biomarkers for Heart Disease
Author: Michael Lichtenauer
Publsiher: MDPI
Total Pages: 420
Release: 2020-12-28
ISBN 10: 3039438832
ISBN 13: 9783039438839
Language: EN, FR, DE, ES & NL

Novel Biomarkers for Heart Disease Book Review:

Cardiac biomarkers such as troponins and natiuretic peptides have made a great impact on clinical decision making as well as improving our understanding of molecular mechanisms of different disease conditions. However, the biomarkers that are currently in use do not reflect all the multiple disease pathways that are involved in a broad spectrum of cardiac disease conditions ranging from acute coronary syndrome, to heart failure (and heart failure with preserved ejection fraction, HFpEF), to pulmonary hypertension or arrhythmias. In this Special Issue, we will provide an overview of the current developments in the field of biomarker research, beginning with research on molecular pathways and cellular communication (e.g., microRNA) up to the clinical use of biomarkers.

Personalized Hip and Knee Joint Replacement

Personalized Hip and Knee Joint Replacement
Author: Anonim
Publsiher: Springer Nature
Total Pages: 350
Release: 2020-01-01
ISBN 10: 3030242439
ISBN 13: 9783030242435
Language: EN, FR, DE, ES & NL

Personalized Hip and Knee Joint Replacement Book Review:

This open access book describes and illustrates the surgical techniques, implants, and technologies used for the purpose of personalized implantation of hip and knee components. This new and flourishing treatment philosophy offers important benefits over conventional systematic techniques, including component positioning appropriate to individual anatomy, improved surgical reproducibility and prosthetic performance, and a reduction in complications. The techniques described in the book aim to reproduce patients native anatomy and physiological joint laxity, thereby improving the prosthetic hip/knee kinematics and functional outcomes in the quest of the forgotten joint. They include kinematically aligned total knee/total hip arthroplasty, partial knee replacement, and hip resurfacing. The relevance of available and emerging technological tools for these personalized approaches is also explained, with coverage of, for example, robotics, computer-assisted surgery, and augmented reality. Contributions from surgeons who are considered world leaders in diverse fields of this novel surgical philosophy make this open access book will invaluable to a wide readership, from trainees at all levels to consultants practicing lower limb surgery.

Joint Arthroplasty

Joint Arthroplasty
Author: Shinichi Imura,Makoto Wada,Hironori Omori
Publsiher: Springer Science & Business Media
Total Pages: 425
Release: 2012-12-06
ISBN 10: 4431685294
ISBN 13: 9784431685296
Language: EN, FR, DE, ES & NL

Joint Arthroplasty Book Review:

The introduction of total joint arthroplasty throughout the world has contributed manifold benefits to patients who suffer from joint diseases. Concurrently, however, there has been an increase in revision surgery. Many orthopedic surgeons agree that durability of prostheses is an eternal problem. In particular, periprosthetic osteolysis recently has been identified as one of the serious problems affecting prosthetic dura bility. To improve durability, osteolysis and many other problems must be investi gated and solved both experimentally and clinically with respect to such aspects as prosthetic material, design, and biological and biomechanical behavior. This book comprises 37 papers that were presented by orthopedic surgeons and biomedical engineers at the 28th Annual Meeting of the Japanese Society for Replace ment Arthroplasty, held in March 1998 in Kanazawa, Japan. The volume is thus a compilation of the latest knowledge about the pathogenesis and reduction of osteolysis and wear, newly developed total hip prostheses, and other current topics of total knee arthroplasty. We earnestly hope that this book will be of benefit to clinicians and researchers, and that it will contribute to the creation of more durable total joint prostheses in the future. SHINICHI IMURA v Contents Preface .................... '" .. .. .. ... . .. .. .. . ... .. . . .. . ... . . .. . V List of Contributors. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . XI . . . . . . . . . . . . Part 1 Wear and Pathogenesis of Osteolysis Friction and Wear of Artificial Joints: A Historical Review N. AKAMATSU ................................................ , 3 Matrix Degradation in Osteoclastic Bone Resorption Under Pathological Conditions .

Orthopedic Surgery

Orthopedic Surgery
Author: Zaid Al-Aubaidi,Andreas Fette
Publsiher: BoD – Books on Demand
Total Pages: 234
Release: 2012-03-09
ISBN 10: 9535102311
ISBN 13: 9789535102311
Language: EN, FR, DE, ES & NL

Orthopedic Surgery Book Review:

Orthopaedic surgery is the widest and the strongest growing surgical specialty. It is clear, that the process of improving treatments and patients care, requires knowledge, and this requires access to studies, expert opinion and books. Unfortunately, the access to this knowledge is being materialized. As we believe that access to the medical knowledge should be reachable to everyone free of charge, this book was generated to cover the orthopaedic aspect. It will provide the reader with a mix of basic, but as well highly specialized knowledge. In the process of editing this book, my wife Jurgita has been, as usual, the most supportive person. I would like to thank her for being in my life. I would like to thank Mr. Greblo, the Publishing Process Manager, for all his help and last but not least thanks to our readers, as without them this book would have no meaning.

Cancer New Insights for the Healthcare Professional 2011 Edition

Cancer  New Insights for the Healthcare Professional  2011 Edition
Author: Anonim
Publsiher: ScholarlyEditions
Total Pages: 3937
Release: 2012-01-09
ISBN 10: 1464900027
ISBN 13: 9781464900020
Language: EN, FR, DE, ES & NL

Cancer New Insights for the Healthcare Professional 2011 Edition Book Review:

Cancer: New Insights for the Healthcare Professional: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Cancer. The editors have built Cancer: New Insights for the Healthcare Professional: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Cancer in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Cancer: New Insights for the Healthcare Professional: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

The Adult Hip

The Adult Hip
Author: Aaron G. Rosenberg,Harry E. Rubash,John Clohisy,Paul Beaule,Craig DellaValle
Publsiher: Lippincott Williams & Wilkins
Total Pages: 1624
Release: 2015-10-13
ISBN 10: 1496318471
ISBN 13: 9781496318473
Language: EN, FR, DE, ES & NL

The Adult Hip Book Review:

This two volume set contains comprehensive coverage of management of disorders of the adult hip. It includes all arthroscopic and open procedures as well as extensive coverage of equipment and prostheses.

Obesity New Insights for the Healthcare Professional 2013 Edition

Obesity  New Insights for the Healthcare Professional  2013 Edition
Author: Anonim
Publsiher: ScholarlyEditions
Total Pages: 820
Release: 2013-07-22
ISBN 10: 1481654721
ISBN 13: 9781481654722
Language: EN, FR, DE, ES & NL

Obesity New Insights for the Healthcare Professional 2013 Edition Book Review:

Obesity: New Insights for the Healthcare Professional: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Diagnosis and Screening. The editors have built Obesity: New Insights for the Healthcare Professional: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Diagnosis and Screening in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Obesity: New Insights for the Healthcare Professional: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Issues in Rheumatology Research and Practice 2011 Edition

Issues in Rheumatology Research and Practice  2011 Edition
Author: Anonim
Publsiher: ScholarlyEditions
Total Pages: 627
Release: 2012-01-09
ISBN 10: 146496615X
ISBN 13: 9781464966156
Language: EN, FR, DE, ES & NL

Issues in Rheumatology Research and Practice 2011 Edition Book Review:

Issues in Rheumatology Research and Practice: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Rheumatology Research and Practice. The editors have built Issues in Rheumatology Research and Practice: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Rheumatology Research and Practice in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Rheumatology Research and Practice: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Infected Total Joint Arthroplasty

Infected Total Joint Arthroplasty
Author: Rihard Trebše
Publsiher: Springer Science & Business Media
Total Pages: 322
Release: 2012-12-14
ISBN 10: 1447124820
ISBN 13: 9781447124825
Language: EN, FR, DE, ES & NL

Infected Total Joint Arthroplasty Book Review:

There are a variety of protocols that are used in infected total joint arthroplasty. This book outlines and details the best possible course of treatment and formulate custom algorithms for every possible case, based on current evidence. It reviews current concepts and “recipes” for the diagnostic and therapeutic procedures (surgical and antibiotic) based on the type of implant, infection and the patient. This book is an essential resource on infected total joint arthroplasty, containing a series of logical and highly detailed instructions that will serve to educate orthopedic surgeons operating in this field on the best approaches, according to detailed and careful research conducted over the last decade.

A Modern Approach to Biofilm Related Orthopaedic Implant Infections

A Modern Approach to Biofilm Related Orthopaedic Implant Infections
Author: Lorenzo Drago
Publsiher: Springer
Total Pages: 119
Release: 2017-06-24
ISBN 10: 3319522744
ISBN 13: 9783319522746
Language: EN, FR, DE, ES & NL

A Modern Approach to Biofilm Related Orthopaedic Implant Infections Book Review:

This book discusses Prosthetic Joint Infection (PJI), which remains one of the most common problems necessitating revision arthroplasty. It pursues a multidisciplinary approach, bringing together opinions from the leading experts in the field. The book identifies the potential causes of these infections, provides sound diagnostic criteria guidelines, and explains how these prosthetic infections are managed from orthopedic surgery, clinical and diagnostic perspectives. PJI can lead to multiple revision surgeries and significant patient morbidity. Periprosthetic infection rates remain around 1–2% after primary total hip and knee arthroplasty and account for approximately 7–12% of all revision cases. Orthopedic hardware infections are much-feared and costly complications that can occur when these devices are implemented both in traumatic cases as well as in joint replacement surgery. Because these infections can lead to higher morbidity, it is important to understand their pathophysiology and the principles behind their diagnosis and initial treatment. The pathogenesis of these kinds of infections is intimately connected to the biofilm-producing trait characteristic of many microorganisms, which can have a critical effect on the likely success of treatments. The book offers a unique guide for all scientists working in arthroplasty who are seeking an update on the field, and for newcomers alike.

Cartilage Injury of the Knee

Cartilage Injury of the Knee
Author: Aaron J. Krych
Publsiher: Springer Nature
Total Pages: 135
Release: 2021
ISBN 10: 3030780511
ISBN 13: 9783030780517
Language: EN, FR, DE, ES & NL

Cartilage Injury of the Knee Book Review:

Principles of Translational Science in Medicine

Principles of Translational Science in Medicine
Author: Martin Wehling
Publsiher: Academic Press
Total Pages: 494
Release: 2021-07-15
ISBN 10: 032399962X
ISBN 13: 9780323999625
Language: EN, FR, DE, ES & NL

Principles of Translational Science in Medicine Book Review:

Principles of Translational Science in Medicine: From Bench to Bedside, Third Edition, provides an update on major achievements in the translation of research into medically relevant results and therapeutics. The book presents a thorough discussion of biomarkers, early human trials, and networking models, and includes institutional and industrial support systems. It also covers algorithms that have influenced all major areas of biomedical research in recent years, resulting in an increasing number of new chemical/biological entities (NCEs or NBEs) as shown in FDA statistics. New chapters include: Translation in Oncology, Biologicals, and Orphan Drugs. The book is ideal for use as a guide for biomedical scientists to establish a systematic approach to translational medicine and is written by worldwide experts in their respective fields. Includes state-of-the-art principles, tools such as biomarkers and early clinical trials, algorithms of translational science in medicine Provides in-depth description of special translational aspects in the currently most successful areas of clinical translation, namely oncology and immunology Covers status of institutionalization of translational medicine, networking structures and outcomes at the level of marketing authorization

Clinical and Imaging Assessment of Metal on Metal Hip Patients

Clinical and Imaging Assessment of Metal on Metal Hip Patients
Author: Reshid Berber
Publsiher: Unknown
Total Pages: 296
Release: 2019
ISBN 10: 1928374650XXX
ISBN 13: OCLC:1167563462
Language: EN, FR, DE, ES & NL

Clinical and Imaging Assessment of Metal on Metal Hip Patients Book Review:

A high failure rate of metal-on-metal (MoM) hip implants prompted regulatory authorities to issue worldwide product recalls. The cause for their failure and decisions surrounding the need for revision is complex due to poor understanding of the toxic effects of metal debris. In addition to local soft tissue destruction, circulating cobalt can cause rare but fatal cardiotoxicity. This thesis describes the detection of metal cobalt-chromium within the liver of a patient with highly elevated blood cobalt (587ppb) using novel MRI imaging techniques, validated by liver biopsy and micro x-ray fluorescence. The prevalence of tissue metal deposition and potential cardiotoxic effects were assessed through a prospective case controlled cohort study. Ninety patients were recruited into three age and gender-matched groups according to blood metal levels. All underwent detailed cardiovascular and liver phenotyping using MRI (for myocardial volumes and function, T2*, T1 and Extra-Cellular Volume mapping), echocardiography, and blood biomarker sampling. T2* is a novel MRI biomarker of tissue metal deposition. Blood cobalt levels among the cohort ranged 0.1 to 118ppb, which is still seen in patients presenting for clinical follow-up. No significant between-group differences were found for cardiac volume or function, nor was there any difference in tissue characterization using T1, T2* and ECV. Higher blood cobalt levels did not translate to increased metal deposition within the heart or liver.The application of these results were analsyed through a multi-disciplianary team setting designed to aid complex decisions of who, when and how to treat MoM patients surgically. By analysis of MDT recommendations compared to the treatment undertaken it was demonstrated that an MDT approach is an acceptable evidence-based aid to decision-making.This thesis concludes that cobalt tissue deposition can be detected using non-invasive MRI techniques, however metal deposition is not commonly seen with blood cobalt levels upto 118ppb with reassuringly little cardiotoxic effects. These results help reassure clinicians managing MoM patients through an MDT approach.