Bioinformatics for Biomedical Science and Clinical Applications

Bioinformatics for Biomedical Science and Clinical Applications
Author: K-H Liang
Publsiher: Elsevier
Total Pages: 170
Release: 2013-07-31
ISBN 10: 1908818239
ISBN 13: 9781908818232
Language: EN, FR, DE, ES & NL

Bioinformatics for Biomedical Science and Clinical Applications Book Review:

Contemporary biomedical and clinical research is undergoing constant development thanks to the rapid advancement of various high throughput technologies at the DNA, RNA and protein levels. These technologies can generate vast amounts of raw data, making bioinformatics methodologies essential in their use for basic biomedical and clinical applications. Bioinformatics for biomedical science and clinical applications demonstrates what these cutting-edge technologies can do and examines how to design an appropriate study, including how to deal with data and address specific clinical questions. The first two chapters consider Bioinformatics and analysis of the human genome. The subsequent three chapters cover the introduction of Transcriptomics, Proteomics and Systems biomedical science. The remaining chapters move on to critical developments, clinical information and conclude with domain knowledge and adaptivity. A coherent presentation of concepts, methodologies and practical tools that systematically lead to significant discoveries in the biomedical and clinical area Real examples of cutting edge discoveries The introduction of study types and technologies for all the DNA, RNA and protein levels

Statistical Advances in the Biomedical Sciences

Statistical Advances in the Biomedical Sciences
Author: Atanu Biswas,Sujay Datta,Jason P. Fine,Mark R. Segal
Publsiher: John Wiley & Sons
Total Pages: 616
Release: 2007-12-14
ISBN 10: 9780470181195
ISBN 13: 0470181192
Language: EN, FR, DE, ES & NL

Statistical Advances in the Biomedical Sciences Book Review:

The Most Comprehensive and Cutting-Edge Guide to Statistical Applications in Biomedical Research With the increasing use of biotechnology in medical research and the sophisticated advances in computing, it has become essential for practitioners in the biomedical sciences to be fully educated on the role statistics plays in ensuring the accurate analysis of research findings. Statistical Advances in the Biomedical Sciences explores the growing value of statistical knowledge in the management and comprehension of medical research and, more specifically, provides an accessible introduction to the contemporary methodologies used to understand complex problems in the four major areas of modern-day biomedical science: clinical trials, epidemiology, survival analysis, and bioinformatics. Composed of contributions from eminent researchers in the field, this volume discusses the application of statistical techniques to various aspects of modern medical research and illustrates how these methods ultimately prove to be an indispensable part of proper data collection and analysis. A structural uniformity is maintained across all chapters, each beginning with an introduction that discusses general concepts and the biomedical problem under focus and is followed by specific details on the associated methods, algorithms, and applications. In addition, each chapter provides a summary of the main ideas and offers a concluding remarks section that presents novel ideas, approaches, and challenges for future research. Complete with detailed references and insight on the future directions of biomedical research, Statistical Advances in the Biomedical Sciences provides vital statistical guidance to practitioners in the biomedical sciences while also introducing statisticians to new, multidisciplinary frontiers of application. This text is an excellent reference for graduate- and PhD-level courses in various areas of biostatistics and the medical sciences and also serves as a valuable tool for medical researchers, statisticians, public health professionals, and biostatisticians.

Cancer Systems Biology Bioinformatics and Medicine

Cancer Systems Biology  Bioinformatics and Medicine
Author: Alfredo Cesario,Frederick Marcus
Publsiher: Springer Science & Business Media
Total Pages: 484
Release: 2011-08-21
ISBN 10: 9789400715677
ISBN 13: 9400715676
Language: EN, FR, DE, ES & NL

Cancer Systems Biology Bioinformatics and Medicine Book Review:

This teaching monograph on systems approaches to cancer research and clinical applications provides a unique synthesis, by world-class scientists and doctors, of laboratory, computational, and clinical methods, thereby establishing the foundations for major advances not possible with current methods. Specifically, the book: 1) Sets the stage by describing the basis of systems biology and bioinformatics approaches, and the clinical background of cancer in a systems context; 2) Summarizes the laboratory, clinical, data systems analysis and bioinformatics tools, along with infrastructure and resources required; 3) Demonstrates the application of these tools to cancer research; 4) Extends these tools and methods to clinical diagnosis, drug development and treatment applications; and 5) Finishes by exploring longer term perspectives and providing conclusions. This book reviews the state-of-the-art, and goes beyond into new applications. It is written and highly referenced as a textbook and practical guide aimed at students, academics, doctors, clinicians, industrialists and managers in cancer research and therapeutic applications. Ideally, it will set the stage for integration of available knowledge to optimize communication between basic and clinical researchers involved in the ultimate fight against cancer, whatever the field of specific interest, whatever the area of activity within translational research.

Java for Bioinformatics and Biomedical Applications

Java for Bioinformatics and Biomedical Applications
Author: Harshawardhan Bal,Johnny Hujol
Publsiher: Springer Science & Business Media
Total Pages: 342
Release: 2007-01-16
ISBN 10: 0387372377
ISBN 13: 9780387372372
Language: EN, FR, DE, ES & NL

Java for Bioinformatics and Biomedical Applications Book Review:

Medical science and practice have undergone fundamental changes in the last 5 years, as large-scale genome projects have resulted in the sequencing of a number of important microbial, plant and animal genomes. This book aims to combine industry standard software engineering and design principles with genomics, bioinformatics and cancer research. Rather than an exercise in learning a programming platform, the text focuses on useful analytical tools for the scientific community.

Application of Clinical Bioinformatics

Application of Clinical Bioinformatics
Author: Xiangdong Wang,Christian Baumgartner,Denis C. Shields,Hong-Wen Deng,Jacques S Beckmann
Publsiher: Springer
Total Pages: 398
Release: 2016-03-31
ISBN 10: 9401775435
ISBN 13: 9789401775434
Language: EN, FR, DE, ES & NL

Application of Clinical Bioinformatics Book Review:

This book elucidates how genetic, biological and medical information can be applied to the development of personalized healthcare, medication and therapies. Focusing on aspects of the development of evidence-based approaches in bioinformatics and computational medicine, including data integration, methodologies, tools and models for clinical and translational medicine, it offers an essential introduction to clinical bioinformatics for clinical researchers and physicians, medical students and teachers, and scientists working with human disease-based omics and bioinformatics. Dr. Xiangdong Wang is a distinguished Professor of Medicine. He is Director of Shanghai Institute of Clinical Bioinformatics, Director of Fudan University Center for Clinical Bioinformatics, Deputy Director of Shanghai Respiratory Research Institute, Director of Biomedical Research Center, Fudan University Zhongshan Hospital, Shanghai, China; Dr. Christian Baumgartner is a Professor of Health Care and Biomedical Engineering at Institute of Health Care Engineering with European Notified Body of Medical Devices, Graz University of Technology, Graz, Austria; Dr. Denis Shields is a Professor of Clinical Bioinformatics at Conway Institute, Belfield, Dublin, Ireland; Dr. Hong-Wen Deng is a Professor at Department of Biostatistics and Bioinformatics, Tulane University School of Public Health and Tropical Medicine, USA; Dr. Jacques S Beckmann is a Professor and Director of Section of Clinical Bioinformatics, Swiss Institute of Bioinformatics, Switzerland.

Computational Methods With Applications In Bioinformatics Analysis

Computational Methods With Applications In Bioinformatics Analysis
Author: Tsai Jeffrey J P,Ng Ka-lok
Publsiher: World Scientific
Total Pages: 232
Release: 2017-06-09
ISBN 10: 981320799X
ISBN 13: 9789813207998
Language: EN, FR, DE, ES & NL

Computational Methods With Applications In Bioinformatics Analysis Book Review:

This compendium contains 10 chapters written by world renowned researchers with expertise in semantic computing, genome sequence analysis, biomolecular interaction, time-series microarray analysis, and machine learning algorithms. The salient feature of this book is that it highlights eight types of computational techniques to tackle different biomedical applications. These techniques include unsupervised learning algorithms, principal component analysis, fuzzy integral, graph-based ensemble clustering method, semantic analysis, interolog approach, molecular simulations and enzyme kinetics. The unique volume will be a useful reference material and an inspirational read for advanced undergraduate and graduate students, computer scientists, computational biologists, bioinformatics and biomedical professionals.

Biomedical Informatics

Biomedical Informatics
Author: Edward H. Shortliffe,James J. Cimino
Publsiher: Springer Science & Business Media
Total Pages: 965
Release: 2013-12-02
ISBN 10: 1447144740
ISBN 13: 9781447144748
Language: EN, FR, DE, ES & NL

Biomedical Informatics Book Review:

The practice of modern medicine and biomedical research requires sophisticated information technologies with which to manage patient information, plan diagnostic procedures, interpret laboratory results, and carry out investigations. Biomedical Informatics provides both a conceptual framework and a practical inspiration for this swiftly emerging scientific discipline at the intersection of computer science, decision science, information science, cognitive science, and biomedicine. Now revised and in its third edition, this text meets the growing demand by practitioners, researchers, and students for a comprehensive introduction to key topics in the field. Authored by leaders in medical informatics and extensively tested in their courses, the chapters in this volume constitute an effective textbook for students of medical informatics and its areas of application. The book is also a useful reference work for individual readers needing to understand the role that computers can play in the provision of clinical services and the pursuit of biological questions. The volume is organized so as first to explain basic concepts and then to illustrate them with specific systems and technologies.

Translational Biotechnology

Translational Biotechnology
Author: Yasha Hasija
Publsiher: Academic Press
Total Pages: 452
Release: 2021-01-17
ISBN 10: 0128219734
ISBN 13: 9780128219737
Language: EN, FR, DE, ES & NL

Translational Biotechnology Book Review:

Translational Biotechnology: A Journey from Laboratory to Clinics presents an integrative and multidisciplinary approach to biotechnology to help readers bridge the gaps between fundamental and functional research. The book provides state-of-the-art and integrative views of translational biotechnology by covering topics from basic concepts to novel methodologies. Topics discussed include biotechnology-based therapeutics, pathway and target discovery, biological therapeutic modalities, translational bioinformatics, and system and synthetic biology. Additional sections cover drug discovery, precision medicine and the socioeconomic impact of translational biotechnology. This book is valuable for bioinformaticians, biotechnologists, and members of the biomedical field who are interested in learning more about this promising field. Explains biotechnology in a different light by using an application-oriented approach Discusses practical approaches in the development of precision medicine tools, systems and dynamical medicine approaches Promotes research in the field of biotechnology that is translational in nature, cost-effective and readily available to the community

Comprehensive Biomedical Physics

Comprehensive Biomedical Physics
Author: Anonim
Publsiher: Newnes
Total Pages: 4056
Release: 2014-07-25
ISBN 10: 0444536337
ISBN 13: 9780444536334
Language: EN, FR, DE, ES & NL

Comprehensive Biomedical Physics Book Review:

Comprehensive Biomedical Physics is a new reference work that provides the first point of entry to the literature for all scientists interested in biomedical physics. It is of particularly use for graduate and postgraduate students in the areas of medical biophysics. This Work is indispensable to all serious readers in this interdisciplinary area where physics is applied in medicine and biology. Written by leading scientists who have evaluated and summarized the most important methods, principles, technologies and data within the field, Comprehensive Biomedical Physics is a vital addition to the reference libraries of those working within the areas of medical imaging, radiation sources, detectors, biology, safety and therapy, physiology, and pharmacology as well as in the treatment of different clinical conditions and bioinformatics. This Work will be valuable to students working in all aspect of medical biophysics, including medical imaging and biomedical radiation science and therapy, physiology, pharmacology and treatment of clinical conditions and bioinformatics. The most comprehensive work on biomedical physics ever published Covers one of the fastest growing areas in the physical sciences, including interdisciplinary areas ranging from advanced nuclear physics and quantum mechanics through mathematics to molecular biology and medicine Contains 1800 illustrations, all in full color

Big Data Analytics in Bioinformatics and Healthcare

Big Data Analytics in Bioinformatics and Healthcare
Author: Wang, Baoying
Publsiher: IGI Global
Total Pages: 528
Release: 2014-10-31
ISBN 10: 1466666129
ISBN 13: 9781466666122
Language: EN, FR, DE, ES & NL

Big Data Analytics in Bioinformatics and Healthcare Book Review:

As technology evolves and electronic data becomes more complex, digital medical record management and analysis becomes a challenge. In order to discover patterns and make relevant predictions based on large data sets, researchers and medical professionals must find new methods to analyze and extract relevant health information. Big Data Analytics in Bioinformatics and Healthcare merges the fields of biology, technology, and medicine in order to present a comprehensive study on the emerging information processing applications necessary in the field of electronic medical record management. Complete with interdisciplinary research resources, this publication is an essential reference source for researchers, practitioners, and students interested in the fields of biological computation, database management, and health information technology, with a special focus on the methodologies and tools to manage massive and complex electronic information.

Translational Bioinformatics and Systems Biology Methods for Personalized Medicine

Translational Bioinformatics and Systems Biology Methods for Personalized Medicine
Author: Qing Yan
Publsiher: Academic Press
Total Pages: 182
Release: 2017-04-18
ISBN 10: 0128043881
ISBN 13: 9780128043882
Language: EN, FR, DE, ES & NL

Translational Bioinformatics and Systems Biology Methods for Personalized Medicine Book Review:

Translational Bioinformatics and Systems Biology Methods for Personalized Medicine introduces integrative approaches in translational bioinformatics and systems biology to support the practice of personalized, precision, predictive, preventive, and participatory medicine. Through the description of important cutting-edge technologies in bioinformatics and systems biology, readers may gain an essential understanding of state-of-the-art methodologies. The book discusses topics such as the challenges and tasks in translational bioinformatics; pharmacogenomics, systems biology, and personalized medicine; and the applicability of translational bioinformatics for biomarker discovery, epigenomics, and molecular dynamics. It also discusses data integration and mining, immunoinformatics, and neuroinformatics. With broad coverage of both basic scientific and clinical applications, this book is suitable for a wide range of readers who may not be scientists but who are also interested in the practice of personalized medicine. Introduces integrative approaches in translational bioinformatics and systems biology to support the practice of personalized, precision, predictive, preventive, and participatory medicine Presents a problem-solving oriented methodology to deal with practical problems in various applications Covers both basic scientific and clinical applications in order to enhance the collaboration between researchers and clinicians Brings integrative and multidisciplinary approaches to bridge the gaps among various knowledge domains in the field

Enhancing the Vitality of the National Institutes of Health

Enhancing the Vitality of the National Institutes of Health
Author: National Research Council,Institute of Medicine,Board on Health Sciences Policy,Division on Earth and Life Studies,Board on Life Sciences,Committee on the Organizational Structure of the National Institutes of Health
Publsiher: National Academies Press
Total Pages: 164
Release: 2003-07-29
ISBN 10: 9780309167116
ISBN 13: 0309167116
Language: EN, FR, DE, ES & NL

Enhancing the Vitality of the National Institutes of Health Book Review:

The report says that important organizational changes are needed at the National Institutes of Health to ensure the agency meets future challenges effectively. In particular, the report advises NIH to devote additional resources to innovative interdisciplinary research that reflects its strategic objectives and cuts across all agency's institutes and centers. The report recommends that Congress should establish a formal process for determining how specific proposals for changes in the number of NIH agencies and centers should be addressed.

Pediatric Biomedical Informatics

Pediatric Biomedical Informatics
Author: John J. Hutton
Publsiher: Springer
Total Pages: 450
Release: 2016-10-08
ISBN 10: 9811011044
ISBN 13: 9789811011047
Language: EN, FR, DE, ES & NL

Pediatric Biomedical Informatics Book Review:

The book describes the core resources in informatics necessary to support biomedical research programs and how these can best be integrated with hospital systems to receive clinical information that is necessary to conduct translational research. The focus is on the authors’ recent practical experiences in establishing an informatics infrastructure in a large research-intensive children’s hospital. This book is intended for translational researchers and informaticians in pediatrics, but can also serve as a guide to all institutions facing the challenges of developing and strengthening informatics support for biomedical research. The first section of the book discusses important technical challenges underlying computer-based pediatric research, while subsequent sections discuss informatics applications that support biobanking and a broad range of research programs. Pediatric Biomedical Informatics provides practical insights into the design, implementation, and utilization of informatics infrastructures to optimize care and research to benefit children.

Biocomputation and Biomedical Informatics Case Studies and Applications

Biocomputation and Biomedical Informatics  Case Studies and Applications
Author: Lazakidou, Athina A.
Publsiher: IGI Global
Total Pages: 356
Release: 2009-11-30
ISBN 10: 1605667692
ISBN 13: 9781605667690
Language: EN, FR, DE, ES & NL

Biocomputation and Biomedical Informatics Case Studies and Applications Book Review:

"This book provides a compendium of terms, definitions, and explanations of concepts, processes, and acronyms"--Provided by publisher.

Bioinformatics Methods in Clinical Research

Bioinformatics Methods in Clinical Research
Author: Rune Matthiesen
Publsiher: Humana Press
Total Pages: 390
Release: 2012-03-01
ISBN 10: 9781617796708
ISBN 13: 1617796700
Language: EN, FR, DE, ES & NL

Bioinformatics Methods in Clinical Research Book Review:

Integrated bioinformatics solutions have become increasingly valuable in past years, as technological advances have allowed researchers to consider the potential of omics for clinical diagnosis, prognosis, and therapeutic purposes, and as the costs of such techniques have begun to lessen. In Bioinformatics Methods in Clinical Research, experts examine the latest developments impacting clinical omics, and describe in great detail the algorithms that are currently used in publicly available software tools. Chapters discuss statistics, algorithms, automated methods of data retrieval, and experimental consideration in genomics, transcriptomics, proteomics, and metabolomics. Composed in the highly successful Methods in Molecular BiologyTM series format, each chapter contains a brief introduction, provides practical examples illustrating methods, results, and conclusions from data mining strategies wherever possible, and includes a Notes section which shares tips on troubleshooting and avoiding known pitfalls. Informative and ground-breaking, Bioinformatics Methods in Clinical Research establishes a much-needed bridge between theory and practice, making it an indispensable resource for bioinformatics researchers.

Genomics and Clinical Diagnostics

Genomics and Clinical Diagnostics
Author: Ralph Rapley,David Whitehouse
Publsiher: Royal Society of Chemistry
Total Pages: 574
Release: 2019-01-29
ISBN 10: 1788016807
ISBN 13: 9781788016803
Language: EN, FR, DE, ES & NL

Genomics and Clinical Diagnostics Book Review:

Genomics and genome technology is having, and continues to have, a major impact on all areas of bioscience research providing insights into the key area of molecular mechanisms of cells in health and disease. This is causing a profound effect on biomedical science and is accelerating the development of new diagnostic applications. This book provides a timely, graduate level introduction to the fast-paced area of genomics and clinical diagnostic technologies and introduces the concept of applications based on this area. The initial chapters focus on principal molecular technologies that underpin the information in the later chapters. In addition to introductory areas of nucleic acids and techniques in molecular biology, bioinformatics and proteomics, other key diagnostic areas such as the use of immunological reagents are covered. The later chapters provide more specialised examples of currently used diagnostic technologies and insights into selected key diagnostic challenges including specific examples of molecular microbial diagnostics and molecular biomarkers in oncology. The running themes through the chapters provides an insight into current and future perspectives in this rapidly evolving field.

Computational Learning Approaches to Data Analytics in Biomedical Applications

Computational Learning Approaches to Data Analytics in Biomedical Applications
Author: Khalid Al-Jabery,Tayo Obafemi-Ajayi,Gayla Olbricht,Donald Wunsch
Publsiher: Academic Press
Total Pages: 310
Release: 2019-11-29
ISBN 10: 0128144831
ISBN 13: 9780128144831
Language: EN, FR, DE, ES & NL

Computational Learning Approaches to Data Analytics in Biomedical Applications Book Review:

Computational Learning Approaches to Data Analytics in Biomedical Applications provides a unified framework for biomedical data analysis using varied machine learning and statistical techniques. It presents insights on biomedical data processing, innovative clustering algorithms and techniques, and connections between statistical analysis and clustering. The book introduces and discusses the major problems relating to data analytics, provides a review of influential and state-of-the-art learning algorithms for biomedical applications, reviews cluster validity indices and how to select the appropriate index, and includes an overview of statistical methods that can be applied to increase confidence in the clustering framework and analysis of the results obtained. Includes an overview of data analytics in biomedical applications and current challenges Updates on the latest research in supervised learning algorithms and applications, clustering algorithms and cluster validation indices Provides complete coverage of computational and statistical analysis tools for biomedical data analysis Presents hands-on training on the use of Python libraries, MATLAB® tools, WEKA, SAP-HANA and R/Bioconductor

Biomedical Applications of Computer Modeling

Biomedical Applications of Computer Modeling
Author: Arthur Christopoulos
Publsiher: CRC Press
Total Pages: 264
Release: 2000-09-19
ISBN 10: 1420041878
ISBN 13: 9781420041873
Language: EN, FR, DE, ES & NL

Biomedical Applications of Computer Modeling Book Review:

Up to the last decade or so, most general modeling approaches to the study of molecular components of biological responses have required significant amount of computer time, expertise, and resources, as well as highly specialized and often custom-written programs. With Biomedical Applications of Computer Modeling you don't have to be a computer scientist to learn valuable modeling techniques. The book represents the first single-volume book that describes general approaches to computer modeling as they apply to the biomedical professions, particularly in the realms of pharmacology and biochemistry. Bringing together contributions from researchers with hands-on expertise, the book is loaded with examples, and it also encompasses different types of computer modeling approaches. In fact, the text supports each modeling approach with clinical examples. It thereby provides a convenient source of readily applicable modeling information. In addition, the book offers easy-to-follow information and presents it in a how-to manner that minimizes the use of mathematical jargon. Biomedical Applications of Computer Modeling includes chapters on equilibrium modeling, dynamic/kinetic modeling, and stochastic modeling, as well as overviews of the application of models to experimental data. With the ubiquitous presence of desktops and notebook computers in biomedical environments, Biomedical Applications of Computer Modeling provides you with an unprecedented means for readily addressing data analysis or computer modeling problems.

Evolution of Translational Omics

Evolution of Translational Omics
Author: Institute of Medicine,Board on Health Sciences Policy,Board on Health Care Services,Committee on the Review of Omics-Based Tests for Predicting Patient Outcomes in Clinical Trials
Publsiher: National Academies Press
Total Pages: 354
Release: 2012-09-13
ISBN 10: 0309224187
ISBN 13: 9780309224185
Language: EN, FR, DE, ES & NL

Evolution of Translational Omics Book Review:

Technologies collectively called omics enable simultaneous measurement of an enormous number of biomolecules; for example, genomics investigates thousands of DNA sequences, and proteomics examines large numbers of proteins. Scientists are using these technologies to develop innovative tests to detect disease and to predict a patient's likelihood of responding to specific drugs. Following a recent case involving premature use of omics-based tests in cancer clinical trials at Duke University, the NCI requested that the IOM establish a committee to recommend ways to strengthen omics-based test development and evaluation. This report identifies best practices to enhance development, evaluation, and translation of omics-based tests while simultaneously reinforcing steps to ensure that these tests are appropriately assessed for scientific validity before they are used to guide patient treatment in clinical trials.

Encyclopedia of Bioinformatics and Computational Biology

Encyclopedia of Bioinformatics and Computational Biology
Author: Anonim
Publsiher: Elsevier
Total Pages: 3284
Release: 2018-08-21
ISBN 10: 0128114320
ISBN 13: 9780128114322
Language: EN, FR, DE, ES & NL

Encyclopedia of Bioinformatics and Computational Biology Book Review:

Encyclopedia of Bioinformatics and Computational Biology: ABC of Bioinformatics combines elements of computer science, information technology, mathematics, statistics and biotechnology, providing the methodology and in silico solutions to mine biological data and processes. The book covers Theory, Topics and Applications, with a special focus on Integrative –omics and Systems Biology. The theoretical, methodological underpinnings of BCB, including phylogeny are covered, as are more current areas of focus, such as translational bioinformatics, cheminformatics, and environmental informatics. Finally, Applications provide guidance for commonly asked questions. This major reference work spans basic and cutting-edge methodologies authored by leaders in the field, providing an invaluable resource for students, scientists, professionals in research institutes, and a broad swath of researchers in biotechnology and the biomedical and pharmaceutical industries. Brings together information from computer science, information technology, mathematics, statistics and biotechnology Written and reviewed by leading experts in the field, providing a unique and authoritative resource Focuses on the main theoretical and methodological concepts before expanding on specific topics and applications Includes interactive images, multimedia tools and crosslinking to further resources and databases