Biofilms and Implantable Medical Devices

Biofilms and Implantable Medical Devices
Author: Ying Deng,Wei Lv
Publsiher: Woodhead Publishing
Total Pages: 238
Release: 2016-10-24
ISBN 10: 0081003986
ISBN 13: 9780081003985
Language: EN, FR, DE, ES & NL

Biofilms and Implantable Medical Devices Book Review:

Biofilms and Implantable Medical Devices: Infection and Control explores the increasing use of permanent and semi-permanent implants and indwelling medical devices. As an understanding of the growth and impact of biofilm formation on these medical devices and biomaterials is vital for protecting the health of the human host, this book provides readers with a comprehensive treatise on biofilms and their relationship with medical devices, also reporting on infections and associated strategies for prevention. Provides useful information on the fundamentals of biofilm problems in medical devices Discusses biofilm problems in a range of medical devices Focuses on strategies for prevention of biofilm formation

Medical Biofilms

Medical Biofilms
Author: Jana Jass,Susanne Surman,James Walker
Publsiher: John Wiley & Sons
Total Pages: 314
Release: 2003-04-02
ISBN 10: 9780471988670
ISBN 13: 0471988677
Language: EN, FR, DE, ES & NL

Medical Biofilms Book Review:

Biofilms are formed by microorganisms growing on surfaces and comprise a series of microcolonies interspersed with spaces through which fluids and other microorganisms move. In medicine, the primary problems are biofilms associated with implants: infections are increasingly difficult to treat with traditional antibiotics and removal of the implant often becomes essential, frequently leading to higher morbidity and mortality. This will be the first book dedicated to medical biofilms. It will cover much recent information on the problems of biofilms, how to detect them and how to control their presence.

Biofilm Eradication and Prevention

Biofilm Eradication and Prevention
Author: Tamilvanan Shunmugaperumal
Publsiher: John Wiley & Sons
Total Pages: 440
Release: 2010-12-28
ISBN 10: 9781118043554
ISBN 13: 1118043553
Language: EN, FR, DE, ES & NL

Biofilm Eradication and Prevention Book Review:

Biofilm Eradication and Preventions presents the basics of biofilm formation on medical devices, diseases related to this formation, and approaches pharmaceutical researchers need to take to limit this problem. Split into three parts, the first deals with the development and characterization of biofilm on the surfaces of implanted or inserted medical devices. Questions as to why biofilms form over medical device surfaces and what triggers biofilm formation are addressed. In the second section, the author discusses biofilm-mediated chronic infections occurred in various organs (eyes, mouth, wounds) and pharmaceutical and drug delivery knowledge gained from research in these area. The third part explores pharmaceutical approaches like lipid-and polymer-based drug delivery carriers for eradicating biofilm on device-related infections. In addition, this section also explores the topic of novel small molecule (like iron and its complexes/metal chelators) and a quorum-sensing inhibitors to control medical biofilm formation.

Biomaterials and Medical Device Associated Infections

Biomaterials and Medical Device   Associated Infections
Author: L Barnes,Ian Cooper
Publsiher: Elsevier
Total Pages: 278
Release: 2014-11-21
ISBN 10: 0857097229
ISBN 13: 9780857097224
Language: EN, FR, DE, ES & NL

Biomaterials and Medical Device Associated Infections Book Review:

Despite advances in materials and sterilisation, patients who receive biomaterials of medical device implants are still at risk of developing an infection around the implantation site. This book reviews the fundamentals of biomaterials and medical device related infections and methods and materials for the treatment and prevention of infection. The first part of the book provides readers with an introduction to the topic including analyses of biofilms, diagnosis and treatment of infection, pathology and topography. The second part of the book discusses a range of established and novel technologies and materials which have been designed to prevent infection. Provides analysis of biofilms and their relevance to implant associated infections. Assesses technologies for controlling biofilms. Considers advantages and disadvantages of in vivo infection studies.

Biofilms in Human Diseases Treatment and Control

Biofilms in Human Diseases  Treatment and Control
Author: Sunil Kumar,Niharika Chandra,Leena Singh,Muhammad Zaffar Hashmi,Ajit Varma
Publsiher: Springer Nature
Total Pages: 311
Release: 2019-11-19
ISBN 10: 3030307573
ISBN 13: 9783030307578
Language: EN, FR, DE, ES & NL

Biofilms in Human Diseases Treatment and Control Book Review:

This book highlights treatment strategies for bacterial biofilms in connection with a variety of human diseases. In particular, it reviews bacterial biofilm formation and its mechanism. Topics covered include biofilms in human health, the role of biofilms in mediating human diseases, and methods for testing bacterial biofilms. Further sections concentrate on biofilm-mediated diseases in different parts of the human gastrointestinal tract, while therapeutic strategies for biofilm control and natural agents that disrupt bacterial biofilms are also covered. Readers will also find the latest advances in probiotics and biofilms, as well as the use of probiotics to counteract biofilm-associated infections. Biofilms and antimicrobial resistance are discussed. Subsequent chapters address the management of inflammatory bowel disease via probiotics biofilms, as well as the role of probiotics bacteria in the treatment of human diseases associated with bacterial biofilms. The book is chiefly intended for clinicians/scientists in the fields of medical microbiology, applied microbiology, biochemistry, and biotechnology.

Microbial Biofilms in Healthcare

Microbial Biofilms in Healthcare
Author: Karen Vickery
Publsiher: MDPI
Total Pages: 166
Release: 2020-03-16
ISBN 10: 303928410X
ISBN 13: 9783039284108
Language: EN, FR, DE, ES & NL

Microbial Biofilms in Healthcare Book Review:

Biofilms are ubiquitous and their presence in industry can lead to production losses. However, nowhere do biofilms impact human health and welfare as much as those that are found contaminating the healthcare environment, surgical instruments, equipment, and medical implantable devices. Approximately 70% of healthcare-associated infections are due to biofilm formation, resulting in increased patient morbidity and mortality. Biofilms formed on medical implants are recalcitrant to antibiotic treatment, which leaves implant removal as the principal treatment option. In this book, we investigate the role of biofilms in breast and dental implant disease and cancer. We include in vitro models for investigating treatment of chronic wounds and disinfectant action against Candida sp. Also included are papers on the most recent strategies for treating biofilm infection ranging from antibiotics incorporated into bone void fillers to antimicrobial peptides and quorum sensing.

Biofilm and Materials Science

Biofilm and Materials Science
Author: Hideyuki Kanematsu,Dana M Barry
Publsiher: Springer
Total Pages: 196
Release: 2015-04-09
ISBN 10: 3319145657
ISBN 13: 9783319145655
Language: EN, FR, DE, ES & NL

Biofilm and Materials Science Book Review:

This book explains the formation of biofilm on materials surfaces in an industrial setting. The authors describe new developments in understanding of biofilm formation, detection, and control from the viewpoint of materials science and engineering. The book details the range of issues caused by biofilm formation and the variety of affected industries.

Antimicrobial Coatings and Modifications on Medical Devices

Antimicrobial Coatings and Modifications on Medical Devices
Author: Zheng Zhang,Victoria E. Wagner
Publsiher: Springer
Total Pages: 273
Release: 2017-05-24
ISBN 10: 3319574949
ISBN 13: 9783319574943
Language: EN, FR, DE, ES & NL

Antimicrobial Coatings and Modifications on Medical Devices Book Review:

Based on a fundamental understanding of the interaction between bacteria and materials, this timely volume emphasizes the latest research in the antimicrobial interfacial design and provides an invaluable blueprint for improving antimicrobial performance on devices and products. Antimicrobial Coatings and Modifications targets reduction of microbial accumulation on biomedical and industrial materials through changing interfacial characteristics. Applying a viable antimicrobial coating or modification to resist alarming threats is a highly demanding requirement for many medical and engineering applications. Many contemporary books in the area of antimicrobial solution focus on applying antimicrobial agents or materials that can kill bacteria. The volume pays more attention to eliminating bacterial contamination and biofilm formation through surface characteristics with minimized bacterial resistance and environmental impact.

Biomaterials Associated Infection

Biomaterials Associated Infection
Author: Fintan Moriarty,Sebastian A.J. Zaat,Henk J. Busscher
Publsiher: Springer Science & Business Media
Total Pages: 566
Release: 2012-09-29
ISBN 10: 1461410312
ISBN 13: 9781461410317
Language: EN, FR, DE, ES & NL

Biomaterials Associated Infection Book Review:

Biomaterials associated infection (BAI) is one of the most common complications associated with implantation of any biomaterial regardless of form or function. These infections usually involve bacterial colonization and biofilm formation on the biomaterial itself, rendering the infection impervious to antimicrobials and host defenses. In addition, it is becoming increasingly clear that infection of the surrounding tissues also plays an important role in BAI, and that the infection may be influenced by the composition and design of the implanted biomaterial. In this book, worldwide leaders in the field address this critical problem in the translation of biomaterials research into clinical practice. The book begins with an emphasis on the latest research in the pathogenesis of BAI from microbiological, immunological, and materials science perspectives. The current state of the art in antimicrobial activation of biomaterials through surface modification and the incorporation of antimicrobial agents is then discussed. In the concluding chapters, successful translation of a selection of antimicrobial technologies from preclinical research into clinical use is described alongside a discussion of the utility of these devices and perspectives for future development. This book is essential reading for researchers and clinicians who are interested in understanding the fundamentals of BAI, the latest in antimicrobial materials research, and the state of the art in clinically available antimicrobial containing medical devices.

Medical Implications of Biofilms

Medical Implications of Biofilms
Author: Michael Wilson,Deirdre Devine
Publsiher: Cambridge University Press
Total Pages: 329
Release: 2003-09-01
ISBN 10: 9781139438018
ISBN 13: 1139438018
Language: EN, FR, DE, ES & NL

Medical Implications of Biofilms Book Review:

Human tissues often support large, complex microbial communities growing as biofilms that can cause a variety of infections. As a result of an increased use of implanted medical devices, the incidence of these biofilm-associated diseases is increasing: the non-shedding surfaces of these devices provide ideal substrata for colonisation by biofilm-forming microbes. The consequences of this mode of growth are far-reaching. As microbes in biofilms exhibit increased tolerance towards antimicrobial agents and decreased susceptibility to host defence systems, biofilm-associated diseases are becoming increasingly difficult to treat. Not surprisingly, therefore, interest in biofilms has increased dramatically. The application of microscopic and molecular techniques has revolutionised our understanding of biofilm structure, composition, organisation, and activities, resulting in important advances in the prevention and treatment of biofilm-related diseases. The purpose of this book, which was first published in 2003, is to bring these advances to the attention of clinicians and medical researchers.

Bacterial Biofilms

Bacterial Biofilms
Author: Tony Romeo
Publsiher: Springer Science & Business Media
Total Pages: 294
Release: 2008-02-26
ISBN 10: 9783540754183
ISBN 13: 3540754180
Language: EN, FR, DE, ES & NL

Bacterial Biofilms Book Review:

Throughout the biological world, bacteria thrive predominantly in surface-attached, matrix-enclosed, multicellular communities or biofilms, as opposed to isolated planktonic cells. This choice of lifestyle is not trivial, as it involves major shifts in the use of genetic information and cellular energy, and has profound consequences for bacterial physiology and survival. Growth within a biofilm can thwart immune function and antibiotic therapy and thereby complicate the treatment of infectious diseases, especially chronic and foreign device-associated infections. Modern studies of many important biofilms have advanced well beyond the descriptive stage, and have begun to provide molecular details of the structural, biochemical, and genetic processes that drive biofilm formation and its dispersion. There is much diversity in the details of biofilm development among various species, but there are also commonalities. In most species, environmental and nutritional conditions greatly influence biofilm development. Similar kinds of adhesive molecules often promote biofilm formation in diverse species. Signaling and regulatory processes that drive biofilm development are often conserved, especially among related bacteria. Knowledge of such processes holds great promise for efforts to control biofilm growth and combat biofilm-associated infections. This volume focuses on the biology of biofilms that affect human disease, although it is by no means comprehensive. It opens with chapters that provide the reader with current perspectives on biofilm development, physiology, environmental, and regulatory effects, the role of quorum sensing, and resistance/phenotypic persistence to antimicrobial agents during biofilm growth.

The Rise of Virulence and Antibiotic Resistance in Staphylococcus aureus

The Rise of Virulence and Antibiotic Resistance in Staphylococcus aureus
Author: Shymaa Enany,Laura Crotty Alexander
Publsiher: BoD – Books on Demand
Total Pages: 224
Release: 2017-03-08
ISBN 10: 953512983X
ISBN 13: 9789535129837
Language: EN, FR, DE, ES & NL

The Rise of Virulence and Antibiotic Resistance in Staphylococcus aureus Book Review:

Staphylococcus aureus S. aureus is a growing issue both within hospitals and community because of its virulence determinants and the continuing emergence of new strains resistant to antimicrobiotics. In this book, we present the state of the art of S. aureus virulence mechanisms and antibiotic-resistance profiles, providing an unprecedented and comprehensive collection of up-to-date research about the evolution, dissemination, and mechanisms of different staphylococcal antimicrobial resistance patterns alongside bacterial virulence determinants and their impact in the medical field. We include several review chapters to allow readers to better understand the mechanisms of methicillin resistance, glycopeptide resistance, and horizontal gene transfer and the effects of alterations in S. aureus membranes and cell walls on drug resistance. In addition, we include chapters dedicated to unveiling S. aureus pathogenicity with the most current research available on S. aureus exfoliative toxins, enterotoxins, surface proteins, biofilm, and defensive responses of S. aureus to antibiotic treatment.

Biofilms in Infection Prevention and Control

Biofilms in Infection Prevention and Control
Author: Steven L. Percival,David Williams,Tracey Cooper,Jacqueline Randle
Publsiher: Academic Press
Total Pages: 394
Release: 2014-01-30
ISBN 10: 0123977517
ISBN 13: 9780123977519
Language: EN, FR, DE, ES & NL

Biofilms in Infection Prevention and Control Book Review:

Biofilms in Infection and Disease Control: A Healthcare Handbook outlines the scientific evidence and rationale for the prevention of infection, the role biofilms play in infection control, and the issues concerning their resistance to antimicrobials. This book provides practical guidance for healthcare and infection control professionals, as well as students, for preventing and controlling infection. Biofilms are the most common mode of bacterial growth in nature. Highly resistant to antibiotics and antimicrobials, biofilms are the source of more than 65 percent of health care associated infections (HCAI), which, according to the WHO, affect 1.4 million people annually. Biofilms are involved in 80 percent of all microbial infections in the body, including those associated with medical devices such as catheters, endotracheal tubes, joint prostheses, and heart valves. Biofilms are also the principle causes of infections of the middle-ear, dental caries, gingivitis, prostatitis and cystic fibrosis. Importantly, biofilms also significantly delay wound healing and reduce antimicrobial efficiency in at-risk or infected skin wounds. Provides specific procedures for controlling and preventing infection Includes case studies of HCAI, and identifies appropriate treatments Presents national government standards for infection prevention and control Includes extensive references and links to websites for further information

Microbial Biofilms

Microbial Biofilms
Author: Mahmoud Ghannoum,George A. O'toole
Publsiher: Amer Society for Microbiology
Total Pages: 426
Release: 2013-03-12
ISBN 10: 9781555818944
ISBN 13: 1555818943
Language: EN, FR, DE, ES & NL

Microbial Biofilms Book Review:

A comprehensive introduction to this exciting and developing field. Covers broad topics, including biofilm development, antibiotic resistance, architecture, and the roles these communities play in disease and industry, and incorporates both bacteria and fungi. Includes a chapter on the history of biofilm biology, written by one of the pioneers in the field, and concludes with ruminations on future directions. Serves as a resource for environmental microbiologists, medical and clinical microbiologists, geologists, biomedical engineers, biotechnologists, and non-experts interested in learning about biofilms, as well as graduate students in biofilm biology courses."

Microbial Biofilms

Microbial Biofilms
Author: Dharumadurai Dhanasekaran,Nooruddin Thajuddin
Publsiher: BoD – Books on Demand
Total Pages: 524
Release: 2016-07-13
ISBN 10: 9535124358
ISBN 13: 9789535124351
Language: EN, FR, DE, ES & NL

Microbial Biofilms Book Review:

In the book Microbial Biofilms: Importance and applications, eminent scientists provide an up-to-date review of the present and future trends on biofilm-related research. This book is divided with four subdivisions as biofilm fundamentals, applications, health aspects, and their control. Moreover, this book also provides a comprehensive account on microbial interactions in biofilms, pyocyanin, and extracellular DNA in facilitating Pseudomonas aeruginosa biofilm formation, atomic force microscopic studies of biofilms, and biofilms in beverage industry. The book comprises a total of 21 chapters from valued contributions from world leading experts in Australia, Bulgaria, Canada, China, Serbia, Germany, Italy, Japan, the United Kingdom, the Kingdom of Saudi Arabia, Republic of Korea, Mexico, Poland, Portugal, and Turkey. This book may be used as a text or reference for everyone interested in biofilms and their applications. It is also highly recommended for environmental microbiologists, soil scientists, medical microbiologists, bioremediation experts, and microbiologists working in biocorrosion, biofouling, biodegradation, water microbiology, quorum sensing, and many other related areas. Scientists in academia, research laboratories, and industry will also find it of interest.

Biofilm formation by staphylococci and streptococci Structural functional and regulatory aspects and implications for pathogenesis

Biofilm formation by staphylococci and streptococci  Structural  functional and regulatory aspects and implications for pathogenesis
Author: Joan A. Geoghegan, Pietro Speziale
Publsiher: Frontiers Media SA
Total Pages: 329
Release: 2015-06-25
ISBN 10: 2889195635
ISBN 13: 9782889195633
Language: EN, FR, DE, ES & NL

Biofilm formation by staphylococci and streptococci Structural functional and regulatory aspects and implications for pathogenesis Book Review:

Members of the genus Staphylococcus and Streptococcus are the causative agnets of many human and animal diseases. Over the past decade the complete sequencing of many staphylococcal and streptococcal genomes has promoted a significant advance in our knowledge of these important pathogens. The pathogenicity of these bacteria is due to the expression of a large variety of virulence factors. Such determinants, which are cell wall-associated and secreted proteins, include adhesins that confer to the pathogen the ability to attach to extracellular matrix/plasma and host cell surfaces, proteins that contribute to host cell invasion and intracellular survival and soluble factors that decrease phagocytosis and modulate the immune response. Furthermore, these Gram-positive cocci in many natural environments (heart valve, lung, oral cavity, throat) and infections on implanted devices live in matrix-encased groups known as biofilms. Biofilms are specialized bacterial communities with high order organization analogous to that of a tissue in multicellular organism that adhere to abiotic or biological substrata and produce an exopolymeric matrix composed of polysaccarides, proteins, DNA or combination thereof. Bacteria within a biofilm persist in adverse conditions, show resistance to killing by antibiotics and to host immune defences and are difficult to eradicate and treat clinically. Therefore, understanding the mechanisms of biofilm development will allow us to effectively combat staphylococcal/streptococcal biofilm-based infections. This Research Topic will focus on the molecular components involved in biofilm formation by staphylococci and streptococci, the role they play in the development, maturation and dispersal of biofilm and on the regulatory aspects of such complex processes. The implication for the pathogenesis of infective diseases and potential therapeutic strategies against biofilm-based infections will be also discussed. The articles will highlight both the recent advances and future challenges inherent in this rapidly evolving area.

Biofilm Infections

Biofilm Infections
Author: Thomas Bjarnsholt,Peter Østrup Jensen,Claus Moser,Niels Høiby
Publsiher: Springer
Total Pages: 314
Release: 2014-10-11
ISBN 10: 9781489982285
ISBN 13: 1489982280
Language: EN, FR, DE, ES & NL

Biofilm Infections Book Review:

This book will cover both the evidence for biofilms in many chronic bacterial infections as well as the problems facing these infections such as diagnostics and treatment regimes. A still increasing interest and emphasis on the sessile bacterial lifestyle biofilms has been seen since it was realized that that less than 0.1% of the total microbial biomass lives in the planktonic mode of growth. The term was coined in 1978 by Costerton et al. who defined the term biofilm for the first time.In 1993 the American Society for Microbiology (ASM) recognised that the biofilmmode of growth was relevant to microbiology. Lately many articles have been published on the clinical implications of bacterial biofilms. Both original articles and reviews concerning the biofilm problem are available.

Antimicrobial Anti Infective Materials

Antimicrobial Anti Infective Materials
Author: Samuel P. Sawan,Gurusamy Manivannan
Publsiher: CRC Press
Total Pages: 346
Release: 1999-12-10
ISBN 10: 1482293943
ISBN 13: 9781482293944
Language: EN, FR, DE, ES & NL

Antimicrobial Anti Infective Materials Book Review:

As our consciousness of microbes increases, it appears that our desire to control our interactions with germs also increases in proportion. This is clearly demonstrated by examining the incredible growth in the number and sales volume of consumer products with antimicrobial claims. In the medical field as well, there is much interest in the use of

Prosthetic Joint Infections

Prosthetic Joint Infections
Author: Trisha Peel
Publsiher: Springer
Total Pages: 263
Release: 2017-11-28
ISBN 10: 3319652508
ISBN 13: 9783319652504
Language: EN, FR, DE, ES & NL

Prosthetic Joint Infections Book Review:

This book outlines the most updated clinical guidelines that are vital for the prevention infections and care of patients with joint infections following a replacement surgery, one of the highest volume medical interventions globally. Sections address the diagnosis, management approaches and prevention of prosthetic joint infections. Written by experts in the field, this text provides a brief overview of the literature and current recommendations in each of the specified areas. Given the rapidly evolving state-of-play in this clinical area, this compendium grows increasingly important to clinicians in their management decisions. Prosthetic Joint Infections is a valuable resource for infectious disease specialists, epidemiologists, surgeons, and orthopedic specialists who may work with patients with prosthetic joint infections.

Handbook of Active Materials for Medical Devices

Handbook of Active Materials for Medical Devices
Author: Andres Diaz Lantada
Publsiher: CRC Press
Total Pages: 350
Release: 2011-09-28
ISBN 10: 9814303364
ISBN 13: 9789814303361
Language: EN, FR, DE, ES & NL

Handbook of Active Materials for Medical Devices Book Review:

This book covers biodevices, mainly implantable or quirurgical, for the diagnosis or treatment of different pathologies, which benefit from the use of active materials as sensors or actuators. Such active or "intelligent" materials are capable of responding in a controlled way to different external physical or chemical stimuli by changing some of their properties. These materials can be used to design and develop sensors, actuators, and multifunctional systems with a large number of applications for developing biodevices and medical appliances. Current work on these fields entails problems related to synthesis, characterization, modeling, simulation, processing, and prototyping technologies, as well as device testing and validation, all of which are treated in depth in this book, for the several types of active or intelligent materials covered. The research presented in this book helps further development of medical devices, based on the additional functionalities that the use of active or "intelligent" materials, both as sensors and actuators, supplies. The main results exposed may help with the industrial expansion of this kind of materials as part of more complex systems.