Application of Brain Oscillations in Neuropsychiatric Diseases

Application of Brain Oscillations in Neuropsychiatric Diseases
Author: Erol Başar,Canan Bașar-Eroğlu,Ayșegül Özerdem,Paolo M. Rossini,Görsev G. Yener
Publsiher: Elsevier Science Health Science Division
Total Pages: 375
Release: 2013
ISBN 10: 9780702053078
ISBN 13: 0702053074
Language: EN, FR, DE, ES & NL

Application of Brain Oscillations in Neuropsychiatric Diseases Book Review:

Brain Oscillations Synchrony and Plasticity

Brain Oscillations  Synchrony and Plasticity
Author: Jos J. Eggermont
Publsiher: Academic Press
Total Pages: 266
Release: 2021-01-25
ISBN 10: 0128204087
ISBN 13: 9780128204085
Language: EN, FR, DE, ES & NL

Brain Oscillations Synchrony and Plasticity Book Review:

Brain Oscillations, Synchrony and Plasticity: Basic Principles and Application to Auditory-Related Disorders discusses the role of brain oscillations, especially with respect to the auditory system and how those oscillations are measured, change over the lifespan, and falter leading to a variety of psychiatric and neurological disorders. The book begins with a description of these cortical rhythm oscillations and how they function in both the normal and pathological brain. It explains how these oscillations are important to auditory, executive and attention brain networks and how they relate to the development, production and deterioration of speech and language. In addition, treatment of malfunctioning cortical rhythms are reviewed using neuromodulation, such as transcranial magnetic, direct current, random noise, and alternating current stimulation, as well as focused ultrasound. The book concludes by describing the potential role of oscillations in dyslexia, autism, schizophrenia and Alzheimer’s disease. Introduces readers to brain imaging methods such as structural and functional magnetic resonance imaging, EEG and magnetoencephalography, in the study of brain oscillations, synchrony and networks of the normal and pathological brain Highlights the role of brain oscillations in perception and cognition, in particular with respect to the auditory system, speech and language Describes lifespan changes, from preterm to senescence, of brain oscillations, brain networks and how they relate to the development and deterioration of speech and language Explains the effects of hearing loss on neural network change in the auditory and non-auditory networks such as the default mode-, the salience-, the executive- and attention networks Illustrates the breakdown of network connections in auditory-related disorders such as tinnitus and in psychiatric disorders with a strong auditory, speech and language component

Arousal in Neurological and Psychiatric Diseases

Arousal in Neurological and Psychiatric Diseases
Author: Edgar Garcia-Rill
Publsiher: Academic Press
Total Pages: 276
Release: 2019-06-18
ISBN 10: 0128179937
ISBN 13: 9780128179932
Language: EN, FR, DE, ES & NL

Arousal in Neurological and Psychiatric Diseases Book Review:

Arousal in Neurological and Psychiatric Diseases focuses on the dysregulation of arousal found in many neurological and psychiatric disorders. Chapters describe the physiology of each process, how it presents in each disorder, and the most appropriate treatment(s). The book also imparts the understanding of the RAS as a system that not only modulates waking, but also survival mechanisms, such as fight vs. flight responses and other reflexes. This book helps neuroscientists, sleep researchers, neurologists and psychiatrists understand the basic mechanisms that modulate arousal in health and disease. In addition, it promotes therapies that can alter the severity and manifestation of multiple disorders. Provides a comprehensive overview of the basic mechanisms behind dysregulation of arousal in neurological and psychiatric disorders Describes, in detail, the function of the Reticular Activating System with respect to higher functions, motor control and the intertwining of arousal and motor disorders Covers multiple neurological disorders, including epilepsy, Alzheimer’s disease, Parkinson’s disease and autism

Genomics Circuits and Pathways in Clinical Neuropsychiatry

Genomics  Circuits  and Pathways in Clinical Neuropsychiatry
Author: Thomas Lehner,Bruce L. Miller,Matthew W. State
Publsiher: Academic Press
Total Pages: 796
Release: 2016-06-07
ISBN 10: 0128005300
ISBN 13: 9780128005309
Language: EN, FR, DE, ES & NL

Genomics Circuits and Pathways in Clinical Neuropsychiatry Book Review:

This foundational work comprehensively examines the current state of the genetics, genomics and brain circuitry of psychiatric and neurological disorders. It consolidates discoveries of specific genes and genomic regions associated with these conditions, the genetic and anatomic architecture of these syndromes, and addresses how recent advances in genomics are leading to a reappraisal of the biology underlying clinical neuroscience. In doing so, it critically examines the promise and limitations of these discoveries toward treatment, and to the interdisciplinary nature of understanding brain and behavior. Coverage includes new discoveries regarding autism, epilepsy, intellectual disability, dementias, movement disorders, language impairment, disorders of attention, schizophrenia, and bipolar disorder. Genomics, Circuits, and Pathways in Clinical Neuropsychiatry focuses on key concepts, challenges, findings, and methods in genetics, genomics, molecular pathways, brain circuitry, and related neurobiology of neurologic and psychiatric disorders. Provides interdisciplinary appeal in psychiatry, neurology, neuroscience, and genetics Identifies key concepts, methods, and findings Includes coverage of multiple disorders from autism to schizophrenia Reviews specific genes associated with disorders Discusses the genetic architecture of these syndromes Explains how recent findings are influencing the understanding of biology Clarifies the promise of these findings for future treatment

Cortical Oscillations in Health and Disease

Cortical Oscillations in Health and Disease
Author: Roger D. Traub,Miles A. Whittington
Publsiher: Oxford University Press, USA
Total Pages: 431
Release: 2010
ISBN 10: 0195342798
ISBN 13: 9780195342796
Language: EN, FR, DE, ES & NL

Cortical Oscillations in Health and Disease Book Review:

This book first reviews the case that brain oscillations not only are important for cognition, as long suspected, but also play a part in the expression of signs and symptoms of neuropsychiatric disorders. The cellular mechanisms of many of the clinically relevant oscillations have been studied by the authors and their colleagues, using in vitro slice methods as well as detailed computer simulations. A surprising insight is that gap junctions between principal neurons play an absolutely critical role in so many types of oscillation in neuronal populations; oscillations are not just the result of properties of individual neurons and their synaptic connections. Furthermore, the way in which gap junctions produce oscillations in the cortex is novel, involving as it does global properties of networks, rather than just the time constants of membrane currents. This insight has implications for therapeutics as well as for our understanding of normal brain functions.

Event Related Dynamics of Brain Oscillations

Event Related Dynamics of Brain Oscillations
Author: Christa Neuper,Wolfgang Klimesch
Publsiher: Elsevier
Total Pages: 464
Release: 2006-12-03
ISBN 10: 9780080465593
ISBN 13: 0080465595
Language: EN, FR, DE, ES & NL

Event Related Dynamics of Brain Oscillations Book Review:

Research on brain oscillations and event-related electroencephalography (EEG) and event-related (de-) synchronization (ERD/ERS) in particular became a rapidly growing field in the last decades. A large number of laboratories worldwide are using ERD/ERS to study cognitive and motor brain function and the importance of this tool in neurocognitive research is widely recognized. This book is a summary of the most current research, methods, and applications of the study of event-related dynamics of brain oscillations. Facing the rapid progress in this field, it brings together, on the one side, fundamental questions of the underlying events, which still remain to be clarified and, on the other side, some of the most significant novel findings, which point to the key topics for future research. In particular, the chapters of this volume cover the neurophysiological fundamentals and models (Section I), new methodological approaches (Section II), current ERD research related to cognitive (Section III) and sensorimotor brain function (Section IV), invasive approaches and clinical applications (Section V), and novel developments of EEG-based brain-computer interfaces and neurofeedback (Section IV).

Brain Dynamics

Brain Dynamics
Author: Erol Başar,Theodore H. Bullock
Publsiher: Springer Science & Business Media
Total Pages: 547
Release: 2012-12-06
ISBN 10: 3642745571
ISBN 13: 9783642745577
Language: EN, FR, DE, ES & NL

Brain Dynamics Book Review:

This volume is based on contributions to the second Brain Dynamics Conference, held in Berlin on August 10-14, 1987, as a satellite conference of the Budapest Congress of the International Brain Research Organization. Like the volume resulting from the first conference, Dynamics of Sensory and Cognitive Processing by the Brain, the present work covers new approaches to brain function, with emphasis on electromagnetic fields, EEG, event-related potentials, connectivistic views, and neural networks. Close attention is also paid to research in the emerging field of deterministic chaos and strange attractors. The diversity of this collection of papers reflects a multipronged advance in a hitherto relatively neglected domain, i. e., the study of signs of dynamic processes in organized neural tissue in order both to explain them and to exploit them for clues to system function. The need is greater than ever for new windows. This volume reflects a historical moment, the moment when a relatively neglected field of basic research into available signs of dynamic processes ongoing in organized neural tissue is expanding almost explosively to complement other approaches. From the topics treated, this book should appeal, as did its predecessor, to neuroscientists, neurologists, scientists studying complex systems, artificial intelligence, and neural networks, psychobiologists, and all basic and clinical investigators concerned with new techniques of monitoring and analyzing the brain's electromagnetic activity.

Neuronal Oscillations of Wakefulness and Sleep

Neuronal Oscillations of Wakefulness and Sleep
Author: Thien Thanh Dang-Vu,Richard Courtemanche
Publsiher: Springer Nature
Total Pages: 277
Release: 2020-05-29
ISBN 10: 1071606530
ISBN 13: 9781071606537
Language: EN, FR, DE, ES & NL

Neuronal Oscillations of Wakefulness and Sleep Book Review:

The purpose of this work is to review recent findings highlighting the mechanisms and functions of the neuronal oscillations that structure brain activity across the sleep-wake cycle. An increasing number of studies conducted in humans and animals, and using a variety of techniques ranging from intracellular recording to functional neuroimaging, has provided important insight into the mechanisms and functional properties of these brain rhythms. Studies of these rhythms are fundamental not only for basic neuroscience, but also for clinical neuroscience. At the basic science level, neuronal oscillations shape the interactions between different areas of the brain and profoundly impact neural responses to the environment, thereby mediating the processing of information in the brain. At the clinical level, brain oscillations are affected in numerous neurological conditions and might provide useful biomarkers that inform about patients’ evolution and vulnerability. During sleep, these brain rhythms could provide functional support to internal states that govern the basic maintenance of local circuit and systemic interactions. During wake, the rhythmicity of cortical and subcortical circuits have been linked with sensory processing, cognitive operations, and preparation for action. This book will attempt to link together these sleep and wake functional roles at the level of neuroimaging and electroencephalographic measures, local field potentials, and even at the cellular level. ​

Rhythms of the Brain

Rhythms of the Brain
Author: Gyorgy Buzsaki
Publsiher: Oxford University Press
Total Pages: 464
Release: 2006-08-03
ISBN 10: 019804125X
ISBN 13: 9780198041252
Language: EN, FR, DE, ES & NL

Rhythms of the Brain Book Review:

This book provides eloquent support for the idea that spontaneous neuron activity, far from being mere noise, is actually the source of our cognitive abilities. In a sequence of "cycles," György Buzsáki guides the reader from the physics of oscillations through neuronal assembly organization to complex cognitive processing and memory storage. His clear, fluid writing-accessible to any reader with some scientific knowledge-is supplemented by extensive footnotes and references that make it just as gratifying and instructive a read for the specialist. The coherent view of a single author who has been at the forefront of research in this exciting field, this volume is essential reading for anyone interested in our rapidly evolving understanding of the brain.

Non Invasive Brain Stimulation in Psychiatry and Clinical Neurosciences

Non Invasive Brain Stimulation in Psychiatry and Clinical Neurosciences
Author: Bernardo Dell'Osso,Giorgio Di Lorenzo
Publsiher: Springer Nature
Total Pages: 370
Release: 2020-09-01
ISBN 10: 3030433560
ISBN 13: 9783030433567
Language: EN, FR, DE, ES & NL

Non Invasive Brain Stimulation in Psychiatry and Clinical Neurosciences Book Review:

This book presents the state of the art regarding the use of non-invasive brain stimulation (TMS and tDCS) in the research and treatment of neuropsychiatric disorders. The contributions, all of which were prepared by internationally recognized experts in the field, are divided into two main sections (for TMS and tDCS, respectively) across diagnoses, following an introductory section on the mechanisms of action and neurophysiological background. Neuropsychological perspectives and approaches are provided as well. The book is ultimately intended to offer a unique, integrated approach to the use of non-invasive brain stimulation across the clinical neurosciences, providing a comprehensive and updated perspective that will benefit psychiatrists, neurologists, clinical psychologists and neurophysiologists alike.

The Oscillatory Nature of Language

The Oscillatory Nature of Language
Author: Elliot Murphy
Publsiher: Cambridge University Press
Total Pages: 285
Release: 2020-09-30
ISBN 10: 1108836313
ISBN 13: 9781108836319
Language: EN, FR, DE, ES & NL

The Oscillatory Nature of Language Book Review:

Develops a theory of how language is processed in the brain and provides a state-of-the-art review of current neuroscientific debates.

Network Neuroscience

Network Neuroscience
Author: Flavio Fröhlich
Publsiher: Academic Press
Total Pages: 482
Release: 2016-09-20
ISBN 10: 0128015861
ISBN 13: 9780128015865
Language: EN, FR, DE, ES & NL

Network Neuroscience Book Review:

Studying brain networks has become a truly interdisciplinary endeavor, attracting students and seasoned researchers alike from a wide variety of academic backgrounds. What has been lacking is an introductory textbook that brings together the different fields and provides a gentle introduction to the major concepts and findings in the emerging field of network neuroscience. Network Neuroscience is a one-stop-shop that is of equal use to the neurobiologist, who is interested in understanding the quantitative methods employed in network neuroscience, and to the physicist or engineer, who is interested in neuroscience applications of mathematical and engineering tools. The book spans 27 chapters that cover everything from individual cells all the way to complex network disorders such as depression and autism spectrum disorders. An additional 12 toolboxes provide the necessary background for making network neuroscience accessible independent of the reader’s background. Dr. Flavio Frohlich (www.networkneuroscientist.org) wrote this book based on his experience of mentoring dozens of trainees in the Frohlich Lab, from undergraduate students to senior researchers. The Frohlich lab (www.frohlichlab.org) pursues a unique and integrated vision that combines computer simulations, animal model studies, human studies, and clinical trials with the goal of developing novel brain stimulation treatments for psychiatric disorders. The book is based on a course he teaches at UNC that has attracted trainees from many different departments, including neuroscience, biomedical engineering, psychology, cell biology, physiology, neurology, and psychiatry. Dr. Frohlich has consistently received rave reviews for his teaching. With this book he hopes to make his integrated view of neuroscience available to trainees and researchers on a global scale. His goal is to make the book the training manual for the next generation of (network) neuroscientists, who will be fusing biology, engineering, and medicine to unravel the big questions about the brain and to revolutionize psychiatry and neurology. Easy-to-read, comprehensive introduction to the emerging field of network neuroscience Includes 27 chapters packed with information on topics from single neurons to complex network disorders such as depression and autism Features 12 toolboxes serve as primers to provide essential background knowledge in the fields of biology, mathematics, engineering, and physics

Brain Body Mind in the Nebulous Cartesian System A Holistic Approach by Oscillations

Brain Body Mind in the Nebulous Cartesian System  A Holistic Approach by Oscillations
Author: Erol Başar
Publsiher: Springer Science & Business Media
Total Pages: 524
Release: 2010-12-06
ISBN 10: 9781441961365
ISBN 13: 1441961364
Language: EN, FR, DE, ES & NL

Brain Body Mind in the Nebulous Cartesian System A Holistic Approach by Oscillations Book Review:

Brain-Body-Mind in the Nebulous Cartesian System: A Holistic Approach by Oscillations is a research monograph, with didactical features, on the mechanisms of the mind, encompassing a wide spectrum of results and analyses. The book should appeal to scientists and graduate students in the fields of neuroscience, neurology, psychiatry, physiology, psychology, physics and philosophy. Its goals are the development of an empirical-analytical construct, denoted as “Reasonings to Approach the Mind”, and the comprehension of 20 principles for understanding the mind. This book amalgamates results from work on the brain, vegetative system, brains in the evolution of species, the maturing brain, dynamic memory, emotional processes, and cognitive impairment in neuro-psychiatric disorders (Alzheimer, Schizophrenia, Bipolar disorders). The findings are comparatively evaluated within the framework of brain oscillations and neurotransmitters. Further, a holistic approach links the brain to the cardiovascular system and overall myogenic coordination of the vegetative system. The results emphasize that EEG oscillations, ultraslow oscillations, and neurotransmitters are quasi-invariant building blocks in brain-body-mind function and also during the evolution of species: The temporal domain is where the importance of research on neural oscillators is indispensable. The core, holistic concept that emerges is that the brain, spinal cord, overall myogenic system, brain-body-oscillations, and neurotransmitters form a functional syncytium. Accordingly, the concept of “Syncytium Brain-Body-Mind” replaces the concept of “Mind”. P>

Closed Loop Neuroscience

Closed Loop Neuroscience
Author: Ahmed El Hady
Publsiher: Academic Press
Total Pages: 304
Release: 2016-09-08
ISBN 10: 0128026413
ISBN 13: 9780128026410
Language: EN, FR, DE, ES & NL

Closed Loop Neuroscience Book Review:

Closed Loop Neuroscience addresses the technical aspects of closed loop neurophysiology, presenting the implementation of these approaches spanning several domains of neuroscience, from cellular and network neurophysiology, through sensory and motor systems, and then clinical therapeutic devices. Although closed-loop approaches have long been a part of the neuroscientific toolbox, these techniques are only now gaining popularity in research and clinical applications. As there is not yet a comprehensive methods book addressing the topic as a whole, this volume fills that gap, presenting state-of-the-art approaches and the technical advancements that enable their application to different scientific problems in neuroscience. Presents the first volume to offer researchers a comprehensive overview of the technical realities of employing closed loop techniques in their work Offers application to in-vitro, in-vivo, and hybrid systems Contains an emphasis on the actual techniques used rather than on specific results obtained Includes exhaustive protocols and descriptions of software and hardware, making it easy for readers to implement the proposed methodologies Encompasses the clinical/neuroprosthetic aspect and how these systems can also be used to contribute to our understanding of basic neurophysiology Edited work with chapters authored by leaders in the field from around the globe – the broadest, most expert coverage available

Fast Oscillations in Cortical Circuits

Fast Oscillations in Cortical Circuits
Author: Roger D. Traub,John G. R.. Jefferys,John G. R. Jefferys,Miles A. Whittington
Publsiher: MIT Press
Total Pages: 324
Release: 1999
ISBN 10: 9780262201186
ISBN 13: 0262201186
Language: EN, FR, DE, ES & NL

Fast Oscillations in Cortical Circuits Book Review:

In Fast Oscillations in Cortical Circuits, the authors use a combination of electrophysiological and computer modeling techniques to analyze how large networks of neurons can produce both epileptic seizures and functionally relevant synchronized oscillations.

Learned Brain Self Regulation for Emotional Processing and Attentional Modulation From Theory to Clinical Applications

Learned Brain Self Regulation for Emotional Processing and Attentional Modulation  From Theory to Clinical Applications
Author: Sergio Ruiz,Ranganatha Sitaram,Niels Birbaumer,Francisco Javier Zamorano
Publsiher: Frontiers Media SA
Total Pages: 329
Release: 2016-10-19
ISBN 10: 2889199800
ISBN 13: 9782889199808
Language: EN, FR, DE, ES & NL

Learned Brain Self Regulation for Emotional Processing and Attentional Modulation From Theory to Clinical Applications Book Review:

Mounting evidence in the last years has demonstrated that self-regulation of brain activity can successfully be achieved by neurofeedback (NF). These methodologies have constituted themselves as new tools for cognitive neuroscience establishing causal links between voluntary brain activations and cognition and behavior, and as potential novel approaches for clinical applications in severe neuropsychiatric disorders (e.g. schizophrenia, depression, Parkinson´s disease, etc.). Current developments of brain imaging-based neurofeedback include the study of the behavioral modifications and neural reorganization produced by learned regulation of the activity of circumscribed brain regions and neuronal network activations. In a rapidly developing field, many open questions and controversies have arisen, i.e. choosing the proper experimental design, the adequate use of control conditions and subjects, the mechanism of learning involved in brain self-regulation, and the still unexplored potential long-lasting effect on brain reorganization and clinical alleviation, among others. This special issue on self-regulation of the brain of emotion and attention using NF approaches interested authors to report technical and methodological advances, scientific investigations in understanding the relation between brain activity and behaviour using NF, and finally studies developing clinical treatment of emotional and attentional disorders. The editors of this special issue anticipate rapid developments in this emerging field.

GABA And Glutamate

GABA And Glutamate
Author: Janko Samardzic
Publsiher: BoD – Books on Demand
Total Pages: 138
Release: 2018-03-21
ISBN 10: 9535138219
ISBN 13: 9789535138211
Language: EN, FR, DE, ES & NL

GABA And Glutamate Book Review:

This book collates the contributions of a selected number of neuroscientists that are interested in the molecular, preclinical, and clinical aspects of neurotransmission research. The seven chapters in this book address the latest research/review data related to GABA/glutamate system's organization and function, the structure of receptors, subtypes and their ligands, as well as the translational approach and clinical implications. The book offers readers a rich collection of data regarding current and future applications of GABA and glutamate neurotransmission, including promising research strategies and potential clinical benefits.

Transcranial Direct Current Stimulation in Neuropsychiatric Disorders

Transcranial Direct Current Stimulation in Neuropsychiatric Disorders
Author: André Brunoni,Michael Nitsche,Colleen Loo
Publsiher: Springer
Total Pages: 414
Release: 2016-09-12
ISBN 10: 3319339672
ISBN 13: 9783319339672
Language: EN, FR, DE, ES & NL

Transcranial Direct Current Stimulation in Neuropsychiatric Disorders Book Review:

The aim of this book is to provide a comprehensive review of the use of Transcranial Direct Current Stimulation (tDCS) in different psychiatric conditions. Here we review tDCS clinical studies employing different types of design (from single-session tDCS studies to randomized clinical trials) as well as studies evaluating the impact of tDCS in neurophysiological, behavioral and brain imaging outcomes. Although the understanding about physiological foundations and effectiveness of clinical therapies of psychiatric diseases has been considerably increased during the last decades, our knowledge is still limited, and consequently psychiatric diseases are still a major burden to the individual patient and society. Recently, interest in pathological alterations of neuroplasticity in psychiatric diseases as a critical condition for development, and amelioration of clinical symptoms increased, caused by the fact that new tools, such as functional imaging, and brain stimulation techniques do allow to monitor, and modulate these phenomena in humans. Especially non-invasive brain stimulation techniques evolved as an attractive potential new therapeutic tool. The interest in non-invasive brain stimulation has grown exponentially in the past 25 years, with the development of non-pharmacological, neuromodulatory techniques such as tDCS and repetitive transcranial magnetic stimulation (rTMS). TDCS, although even newer than rTMS, has attracted considerable attention in both basic and clinical research scenarios. In the context of clinical research, tDCS is being increasingly investigated as a novel treatment tool for several psychiatric disorders, such as major depression, schizophrenia and neurocognitive and substance abuse disorders. Transcranial Direct Current Stimulation in Neuropsychiatric Disorders – Clinical Principles and Management intends to serve as a practical guide on the field, attracting the interest of psychiatrists, neurologists and neuroscientists with little or no experience with tDCS, as well as those with a background on tDCS who want to increase their knowledge in any particular psychiatric condition.

The Oxford Handbook of Event Related Potential Components

The Oxford Handbook of Event Related Potential Components
Author: Steven J. Luck
Publsiher: OUP USA
Total Pages: 641
Release: 2012-01-12
ISBN 10: 0195374142
ISBN 13: 9780195374148
Language: EN, FR, DE, ES & NL

The Oxford Handbook of Event Related Potential Components Book Review:

The Oxford Handbook of Event-Related Potential Components provides a detailed and comprehensive overview of the major ERP components. It covers components related to multiple research domains, including perception, cognition, emotion, neurological and psychiatric disorders, and lifespan development.

Alcohol and the Nervous System

Alcohol and the Nervous System
Author: Edith V. Sullivan,Adolf Pfefferbaum
Publsiher: Elsevier
Total Pages: 704
Release: 2014-10-08
ISBN 10: 0444626220
ISBN 13: 9780444626226
Language: EN, FR, DE, ES & NL

Alcohol and the Nervous System Book Review:

Alcohol is the most widely used drug in the world, yet alcoholism remains a serious addiction affecting nearly 20 million Americans. Our current understanding of alcohol's effect on brain structure and related functional damage is being revolutionized by genetic research, basic neuroscience, brain imaging science, and systematic study of cognitive, sensory, and motor abilities. Volume 125 of the Handbook of Clinical Neurology is a comprehensive, in-depth treatise of studies on alcohol and the brain covering the basic understanding of alcohol's effect on the central nervous system, the diagnosis and treatment of alcoholism, and prospect for recovery. The chapters within will be of interest to clinical neurologists, neuropsychologists, and researchers in all facets and levels of the neuroscience of alcohol and alcoholism. The first focused reference specifically on alcohol and the brain Details our current understanding of how alcohol impacts the central nervous system Covers clinical and social impact of alcohol abuse disorders and the biomedical consequences of alcohol abuse Includes section on neuroimaging of neurochemical markers and brain function