Antimalarial Agents

Antimalarial Agents
Author: Graham L. Patrick
Publsiher: Elsevier
Total Pages: 622
Release: 2020-05-30
ISBN 10: 0081012411
ISBN 13: 9780081012413
Language: EN, FR, DE, ES & NL

Antimalarial Agents Book Review:

Antimalarial Agents: Design and Mechanism of Action seeks to support medicinal chemists in their work towards antimalarial solution, providing practical guidance on current developments and highlighting promising leads for the future. Malaria is a deadly disease which threatens half of the world’s population. Advances over the last decade have seen vast improvements in the effectiveness of both preventative measures and treatments, but the rapid adaptability of the disease means that the ongoing search for improved and novel antimalarial drugs is essential. Beginning with a focus on biological aspects of malaria, this book highlights the lifecycle of the parasite responsible for malaria, the problem of resistance, genetic mapping of the parasite’s genome, established drug targets, and potential drug targets for the future. The book also includes detailed study of the medicinal chemistry of antimalarial agents and a focus on the design of antimalarial drugs. Drawing on the knowledge of its expert authors and coupling historic research with current findings to provide a full picture of both past and current milestones, Antimalarial Agents: Design and Mechanism of Action is a comprehensive yet accessible guide for all those involved in the design, development and administration of antimalarial drugs, including academic researchers, medicinal chemists, malaria researchers and pharmaceutical scientists. Consolidates both past and current developments in the discovery and design of antimalarial drugs Presents content in a style that is both thorough and engaging, providing a supportive and guiding reference to students and researchers from interdisciplinary backgrounds Highlights drug targets currently considered to be the most promising for future therapies, and the classes of compounds that are currently being studied and perfected

Antimalarial Agents

Antimalarial Agents
Author: Graham L. Patrick
Publsiher: Elsevier
Total Pages: 622
Release: 2020-06-16
ISBN 10: 0081012101
ISBN 13: 9780081012109
Language: EN, FR, DE, ES & NL

Antimalarial Agents Book Review:

Antimalarial Agents: Design and Mechanism of Action seeks to support medicinal chemists in their work toward antimalarial solutions, providing practical guidance on past and current developments and highlighting promising leads for the future. Malaria is a deadly disease which threatens half of the world's population. Advances over several decades have seen vast improvements in the eff ectiveness of both preventative measures and treatments, but the rapid adaptability of the disease means that the ongoing search for improved and novel antimalarial drugs is essential. Beginning with a historical overview of malaria and antimalarial research, this book goes on to describe the biological aspects of malaria, highlighting the lifecycle of the parasite responsible for malaria, the problem of resistance, genetic mapping of the parasite's genome, established drug targets, and potential drug targets for the future. This sets the scene for the following chapters which provide a detailed study of the medicinal chemistry of antimalarial agents, with a focus on the design of antimalarial drugs. Drawing on the knowledge of its experienced authors, and coupling historic research with current fi ndings to provide a full picture of both past and current milestones, Antimalarial Agents: Design and Mechanism of Action is a comprehensive yet accessible guide for all those involved in the design, development, and administration of antimalarial drugs, including student academic researchers, medicinal chemists, malaria researchers, and pharmaceutical scientists. Consolidates both past and current developments in the discovery and design of antimalarial drugs Presents content in a style that is both thorough and engaging, providing a supportive and guiding reference to students and researchers from interdisciplinary backgrounds Highlights drug targets currently considered to be the most promising for future therapies, and the classes of compounds that are currently being studied and perfected

Antimalarial Agents

Antimalarial Agents
Author: Poul Thompson
Publsiher: Elsevier
Total Pages: 408
Release: 2012-12-02
ISBN 10: 032315168X
ISBN 13: 9780323151689
Language: EN, FR, DE, ES & NL

Antimalarial Agents Book Review:

Medicinal Chemistry, Volume 12: Antimalarial Agents: Chemistry and Pharmacology presents the essentials of both biology and chemistry pertinent to the chemotherapy of malaria. This book discusses the nature of the disease, the physiology and biochemistry of the plasmodia, and the mode of action of drugs. Organized into 19 chapters, this volume begins with an overview of the most intensive efforts to develop synthetic antimalarial drugs. This text then examines how drugs are evaluated as well as the specific chemotherapy in malaria. Other chapters consider the diversity of chemical structures exhibiting antimalarial activity with emphasis on structure–activity relationships and methods of synthesis. This book discusses as well the plasmodial effects by quinine in vivo. The final chapter deals with the miscellaneous structures known to have activity against some types of plasmodial infection in animals. This book is a valuable resource for chemists and biologists involved in the development of antimalarial drugs.

Antimalarial Agents Advances in Research and Application 2011 Edition

Antimalarial Agents  Advances in Research and Application  2011 Edition
Author: Anonim
Publsiher: ScholarlyEditions
Total Pages: 26
Release: 2012-01-09
ISBN 10: 1464949840
ISBN 13: 9781464949845
Language: EN, FR, DE, ES & NL

Antimalarial Agents Advances in Research and Application 2011 Edition Book Review:

Antimalarial Agents: Advances in Research and Application: 2011 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Antimalarial Agents in a compact format. The editors have built Antimalarial Agents: Advances in Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Antimalarial Agents in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Antimalarial Agents: Advances in Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Antimalarial Agents An Update on Synthetic Variants of Chloroquine

Antimalarial Agents  An Update on Synthetic Variants of Chloroquine
Author: Anupama Parate
Publsiher: Anonim
Total Pages: 329
Release: 2019
ISBN 10: 9783659876677
ISBN 13: 3659876674
Language: EN, FR, DE, ES & NL

Antimalarial Agents An Update on Synthetic Variants of Chloroquine Book Review:

Saving Lives Buying Time

Saving Lives  Buying Time
Author: Institute of Medicine,Board on Global Health,Committee on the Economics of Antimalarial Drugs
Publsiher: National Academies Press
Total Pages: 384
Release: 2004-10-09
ISBN 10: 0309092183
ISBN 13: 9780309092180
Language: EN, FR, DE, ES & NL

Saving Lives Buying Time Book Review:

For more than 50 years, low-cost antimalarial drugs silently saved millions of lives and cured billions of debilitating infections. Today, however, these drugs no longer work against the deadliest form of malaria that exists throughout the world. Malaria deaths in sub-Saharan Africaâ€"currently just over one million per yearâ€"are rising because of increased resistance to the old, inexpensive drugs. Although effective new drugs called “artemisinins†are available, they are unaffordable for the majority of the affected population, even at a cost of one dollar per course. Saving Lives, Buying Time: Economics of Malaria Drugs in an Age of Resistance examines the history of malaria treatments, provides an overview of the current drug crisis, and offers recommendations on maximizing access to and effectiveness of antimalarial drugs. The book finds that most people in endemic countries will not have access to currently effective combination treatments, which should include an artemisinin, without financing from the global community. Without funding for effective treatment, malaria mortality could double over the next 10 to 20 years and transmission will intensify.

Survey of Antimalarial Agents

Survey of Antimalarial Agents
Author: George Robert Coatney
Publsiher: Anonim
Total Pages: 323
Release: 1953
ISBN 10:
ISBN 13: CORNELL:31924018502942
Language: EN, FR, DE, ES & NL

Survey of Antimalarial Agents Book Review:

STERIC HINDRANCE AND SYNERGISM IN THE DESIGN OF ANTIMALARIAL AGENTS

STERIC HINDRANCE AND SYNERGISM IN THE DESIGN OF ANTIMALARIAL AGENTS
Author: DOUGLAS CLIFFORD MORRISON
Publsiher: Anonim
Total Pages: 68
Release: 1964
ISBN 10:
ISBN 13: UOM:39015032276696
Language: EN, FR, DE, ES & NL

STERIC HINDRANCE AND SYNERGISM IN THE DESIGN OF ANTIMALARIAL AGENTS Book Review:

Antimalarial Chemotherapy

Antimalarial Chemotherapy
Author: Philip J. Rosenthal
Publsiher: Springer Science & Business Media
Total Pages: 396
Release: 2001-04-01
ISBN 10: 1592591116
ISBN 13: 9781592591114
Language: EN, FR, DE, ES & NL

Antimalarial Chemotherapy Book Review:

Philip Rosenthal, MD, and a panel of leading malaria experts drawn from academia, the military, and international health organizations survey the latest scientific understanding of antimalarial chemotherapy, emphasizing the molecular mechanisms of resistance and the description of important new targets. Their survey covers the current status of malarial and antimalarial chemotherapy, the relevant biology and biochemistry of malaria parasites, the antimalarial drugs currently available, new chemical approaches to chemotherapy, and possible new targets for chemotherapy. Comprehensive and cutting-edge, Antimalarial Chemotherapy: Mechanisms of Action, Resistance, and New Directions in Drug Discovery clearly delineates all the basic and clinical research now addressing one of the world's major unresolved disease problems, work that is now powerfully driving the rapid pace of antimalarial drug discovery today.

Exam Prep for Antimalarial Agents Chemistry And

Exam Prep for  Antimalarial Agents  Chemistry And
Author: Anonim
Publsiher: Anonim
Total Pages: 329
Release:
ISBN 10:
ISBN 13:
Language: EN, FR, DE, ES & NL

Exam Prep for Antimalarial Agents Chemistry And Book Review:

Pediatric Dermatology E Book

Pediatric Dermatology E Book
Author: Lawrence A. Schachner,Ronald C. Hansen
Publsiher: Elsevier Health Sciences
Total Pages: 1912
Release: 2011-02-08
ISBN 10: 0723436657
ISBN 13: 9780723436652
Language: EN, FR, DE, ES & NL

Pediatric Dermatology E Book Book Review:

The latest edition of Pediatric Dermatology, edited by Lawrence A. Schachner, MD and Ronald C. Hansen, MD brings you the detailed guidance you need to effectively diagnose and treat pediatric skin conditions. Review topics from keratinization to stem cell therapy, and gain expert guidance from international contributors. Now in a comprehensive format with 40% all new clinical photos, this resource is ideal for clinical practice. Refer to full-color photographs that accurately capture the appearance of a wide range of skin disorders. Access many new tables and therapeutic algorithms for at-a-glance guidance. Recognize distinguishing factors in skin lesions with 40% new and improved clinical photographs. Find extended coverage of topics like genodermatoses and disorders of keratinization, review excellent information on skin neoplasms in children, new systemic therapies, and viral disorders, and explore new concepts in autoinflammatory disorders and Kawasaki’s disease. Read up on best practices and stay at the forefront of your profession with new perspectives from a host of international contributors like new Associate Editor Antonio Torrello, who co-edits the Pediatric Dermatology journal.

Contribution of Mass Spectrometry to the Study of Antimalarial Agents

Contribution of Mass Spectrometry to the Study of Antimalarial Agents
Author: Ana Raquel Sitoe
Publsiher: Anonim
Total Pages: 329
Release: 2013
ISBN 10:
ISBN 13: OCLC:1154248500
Language: EN, FR, DE, ES & NL

Contribution of Mass Spectrometry to the Study of Antimalarial Agents Book Review:

Contribution of Mass Spectrometry to the Study of Antimalarial Agents.

Tandem Mass Spectrometry

Tandem Mass Spectrometry
Author: Ana Varela Coelho,Catarina De Matos Ferraz Franco
Publsiher: BoD – Books on Demand
Total Pages: 206
Release: 2013-05-29
ISBN 10: 9535111361
ISBN 13: 9789535111368
Language: EN, FR, DE, ES & NL

Tandem Mass Spectrometry Book Review:

Tandem Mass Spectrometry - Molecular Characterization presents a comprehensive coverage of theory, instrumentation and description of experimental strategies and MS/MS data interpretation for the structural characterization of relevant molecular compounds. The areas covered include the analysis of drugs, metabolites, carbohydrates and protein post-translational modifications. The book series in Tandem Mass Spectrometry serves multiple groups of audiences; professional (academic and industry), graduate students and general readers interested in the use of modern mass spectrometry in solving critical questions of chemical and biological sciences.

Assessment of Long Term Health Effects of Antimalarial Drugs When Used for Prophylaxis

Assessment of Long Term Health Effects of Antimalarial Drugs When Used for Prophylaxis
Author: National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Population Health and Public Health Practice
Publsiher: National Academies Press
Total Pages: 426
Release: 2020-03-24
ISBN 10: 0309672139
ISBN 13: 9780309672139
Language: EN, FR, DE, ES & NL

Assessment of Long Term Health Effects of Antimalarial Drugs When Used for Prophylaxis Book Review:

Among the many who serve in the United States Armed Forces and who are deployed to distant locations around the world, myriad health threats are encountered. In addition to those associated with the disruption of their home life and potential for combat, they may face distinctive disease threats that are specific to the locations to which they are deployed. U.S. forces have been deployed many times over the years to areas in which malaria is endemic, including in parts of Afghanistan and Iraq. Department of Defense (DoD) policy requires that antimalarial drugs be issued and regimens adhered to for deployments to malaria-endemic areas. Policies directing which should be used as first and as second-line agents have evolved over time based on new data regarding adverse events or precautions for specific underlying health conditions, areas of deployment, and other operational factors At the request of the Veterans Administration, Assessment of Long-Term Health Effects of Antimalarial Drugs When Used for Prophylaxis assesses the scientific evidence regarding the potential for long-term health effects resulting from the use of antimalarial drugs that were approved by FDA or used by U.S. service members for malaria prophylaxis, with a focus on mefloquine, tafenoquine, and other antimalarial drugs that have been used by DoD in the past 25 years. This report offers conclusions based on available evidence regarding associations of persistent or latent adverse events.

Hepatotoxicity

Hepatotoxicity
Author: Hyman J. Zimmerman
Publsiher: Lippincott Williams & Wilkins
Total Pages: 789
Release: 1999
ISBN 10: 9780781719520
ISBN 13: 0781719526
Language: EN, FR, DE, ES & NL

Hepatotoxicity Book Review:

Written by the foremost authority in the field, this volume is a comprehensive review of the multifaceted phenomenon of hepatotoxicity. Dr. Zimmerman examines the interface between chemicals and the liver; the latest research in experimental hepatotoxicology; the hepatotoxic risks of household, industrial, and environmental chemicals; and the adverse effects of drugs on the liver. This thoroughly revised, updated Second Edition features a greatly expanded section on the wide variety of drugs that can cause liver injury. For quick reference, an appendix lists these medications and their associated hepatic injuries. Also included are in-depth discussions of drug metabolism and factors affecting susceptibility to liver injury.

Redox active 3 benzyl menadiones as New Antimalarial Agents Studies on Structure activity Relationships Antiparasitic Potency and Mechanism of Action

Redox active 3 benzyl menadiones as New Antimalarial Agents  Studies on Structure activity Relationships  Antiparasitic Potency and Mechanism of Action
Author: Katharina Ehrhardt
Publsiher: Anonim
Total Pages: 329
Release: 2017
ISBN 10:
ISBN 13: OCLC:1137000748
Language: EN, FR, DE, ES & NL

Redox active 3 benzyl menadiones as New Antimalarial Agents Studies on Structure activity Relationships Antiparasitic Potency and Mechanism of Action Book Review:

Current Topics in Malaria

Current Topics in Malaria
Author: Alfonso J. Rodriguez-Morales
Publsiher: Anonim
Total Pages: 506
Release: 2016-11-30
ISBN 10: 9535127896
ISBN 13: 9789535127895
Language: EN, FR, DE, ES & NL

Current Topics in Malaria Book Review:

Psychiatric Side Effects of Prescription and Over the counter Medications

Psychiatric Side Effects of Prescription and Over the counter Medications
Author: Thomas Markham Brown,Alan Stoudemire
Publsiher: American Psychiatric Pub
Total Pages: 443
Release: 1998
ISBN 10: 9780880488686
ISBN 13: 0880488689
Language: EN, FR, DE, ES & NL

Psychiatric Side Effects of Prescription and Over the counter Medications Book Review:

Both prescription and non-prescription medications used in medicine and psychiatry can cause a varietyof problems for those taking them, both in terms of their behavior and their ability to think. The first book to thoroughly examine how to recognize and manage the psychological side-effects of these medicines, this exhaustive work also provides a fingertip source of vital information for everyone from psychiatrists, primary care doctors and other medical subspecialty practitioners to students, residents and general readers. Noted physicians Thomas Markham Brown and Alan Stoudemire cover all of the major medications used in medicine and psychiatry, with full chapters on such topics as: * Antipsychotics* Antidepressants* Lithium* Anticonvulsants* Anesthetic agents* Sedative-Hypnotic and related agents* Antibiotics* Cardiovascular agents* Antineoplastic agents* Gastrointestinal agents* Pulmonary agents* Hematologic agents* Antilipemic agents* Drugs affecting the endocrine system Throughout this information-packed reference, the authors, noted physicians Thomas Markham Brown and Alan Stoudemire, cover all of the major medications used in medicine and psychiatry. They focus on the fundamental ways drugs cause cognitive toxicity and map strategies for clinical management. They also address the consequences of drug interactions and the basic pathophysiology of central nervous system toxicity. With the help of Psychiatric Side Effects of Prescription and Over-the-Counter Medications, readers will be able to quickly identify the ways drugs sometimes negatively affect behavior and ability to reason, and then determine the best practical course for treating those problems. A CD-ROM containing the complete contents of Psychiatric Side Effects of Prescription and Over the Counter Medications is included. Fully searchable, this CD-ROM is compatible on both MACINTOSH and WINDOWS systems.

Treatment and Prevention of Malaria

Treatment and Prevention of Malaria
Author: Henry M. Staines,Sanjeev Krishna
Publsiher: Springer Science & Business Media
Total Pages: 318
Release: 2012-01-05
ISBN 10: 3034604807
ISBN 13: 9783034604802
Language: EN, FR, DE, ES & NL

Treatment and Prevention of Malaria Book Review:

Malaria has defeated previous efforts at eradication and remains a massive global public health problem despite being readily preventable and treatable. It is a devastating disease that also extracts huge economic costs from the poorest countries in endemic regions. Starting with an overview of the disease and its current political, financial and technical context, this Milestones in Drug Therapy volume describes the history, chemistry, mechanisms of action and resistance, preclinical and clinical use, pharmacokinetics and safety and tolerability of the current range of antimalarial drugs. There is particular emphasis on artemisinins and related peroxides, as these drugs have now become the frontline treatment for malaria. Next generation antimalarials, molecular markers for detecting resistance, the importance of diagnostics and disease prevention are also covered in detail.

The Harriet Lane Handbook of Pediatric Antimicrobial Therapy E Book

The Harriet Lane Handbook of Pediatric Antimicrobial Therapy E Book
Author: Julia McMillan,Carlton K. Lee,George K. Siberry,Karen Carroll
Publsiher: Elsevier Health Sciences
Total Pages: 640
Release: 2012-05-15
ISBN 10: 0323112641
ISBN 13: 9780323112642
Language: EN, FR, DE, ES & NL

The Harriet Lane Handbook of Pediatric Antimicrobial Therapy E Book Book Review:

From the experts at Johns Hopkins University who bring you the bestselling Harriet Lane Handbook, the Harriet Lane Handbook of Pediatric Antimicrobial Therapy delivers quick, dependable answers to help you effectively treat a broad spectrum of pediatric infectious diseases. This highly regarded medical reference book is your pocket-sized source for all of the evidence-based recommendations you need to provide the best possible care to your young patients. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Get all of the information you need to prescribe the correct drug and the appropriate dose through a detailed drug formulary, expanded from the popular Harriet Lane Handbook. Better manage persistent, hard-to-fight pediatric infections with a section on adverse effects and drug resistance. Make the best clinical decisions with up-to-date practice guidelines from the AAP, CDC, and other authoritative pediatric and infectious disease sources. Stay on top of the most effective treatments with leading-edge coverage of antiretroviral drugs for HIV and hepatitis; antimicrobial pharmacokinetic/pharmacodynamics (PK/PD) information; the latest Vancomycin therapeutic drug-monitoring recommendations; antimicrobial desensitization; pediatric developmental effects of antimicrobials approved in adults but not children; and much more. Depend on the professional wisdom of an expert author team, combined with the front-line input of current pediatric infectious disease fellows.