Antimalarial Agents

Antimalarial Agents
Author: Graham L. Patrick
Publsiher: Elsevier
Total Pages: 622
Release: 2020-06-16
ISBN 10: 0081012101
ISBN 13: 9780081012109
Language: EN, FR, DE, ES & NL

Antimalarial Agents Book Review:

Antimalarial Agents: Design and Mechanism of Action seeks to support medicinal chemists in their work toward antimalarial solutions, providing practical guidance on past and current developments and highlighting promising leads for the future. Malaria is a deadly disease which threatens half of the world's population. Advances over several decades have seen vast improvements in the eff ectiveness of both preventative measures and treatments, but the rapid adaptability of the disease means that the ongoing search for improved and novel antimalarial drugs is essential. Beginning with a historical overview of malaria and antimalarial research, this book goes on to describe the biological aspects of malaria, highlighting the lifecycle of the parasite responsible for malaria, the problem of resistance, genetic mapping of the parasite's genome, established drug targets, and potential drug targets for the future. This sets the scene for the following chapters which provide a detailed study of the medicinal chemistry of antimalarial agents, with a focus on the design of antimalarial drugs. Drawing on the knowledge of its experienced authors, and coupling historic research with current fi ndings to provide a full picture of both past and current milestones, Antimalarial Agents: Design and Mechanism of Action is a comprehensive yet accessible guide for all those involved in the design, development, and administration of antimalarial drugs, including student academic researchers, medicinal chemists, malaria researchers, and pharmaceutical scientists. Consolidates both past and current developments in the discovery and design of antimalarial drugs Presents content in a style that is both thorough and engaging, providing a supportive and guiding reference to students and researchers from interdisciplinary backgrounds Highlights drug targets currently considered to be the most promising for future therapies, and the classes of compounds that are currently being studied and perfected

Antimalarial Agents

Antimalarial Agents
Author: Poul Thompson
Publsiher: Elsevier
Total Pages: 408
Release: 2012-12-02
ISBN 10: 032315168X
ISBN 13: 9780323151689
Language: EN, FR, DE, ES & NL

Antimalarial Agents Book Review:

Medicinal Chemistry, Volume 12: Antimalarial Agents: Chemistry and Pharmacology presents the essentials of both biology and chemistry pertinent to the chemotherapy of malaria. This book discusses the nature of the disease, the physiology and biochemistry of the plasmodia, and the mode of action of drugs. Organized into 19 chapters, this volume begins with an overview of the most intensive efforts to develop synthetic antimalarial drugs. This text then examines how drugs are evaluated as well as the specific chemotherapy in malaria. Other chapters consider the diversity of chemical structures exhibiting antimalarial activity with emphasis on structure–activity relationships and methods of synthesis. This book discusses as well the plasmodial effects by quinine in vivo. The final chapter deals with the miscellaneous structures known to have activity against some types of plasmodial infection in animals. This book is a valuable resource for chemists and biologists involved in the development of antimalarial drugs.

Hepatotoxicity

Hepatotoxicity
Author: Hyman J. Zimmerman
Publsiher: Lippincott Williams & Wilkins
Total Pages: 789
Release: 1999
ISBN 10: 9780781719520
ISBN 13: 0781719526
Language: EN, FR, DE, ES & NL

Hepatotoxicity Book Review:

Written by the foremost authority in the field, this volume is a comprehensive review of the multifaceted phenomenon of hepatotoxicity. Dr. Zimmerman examines the interface between chemicals and the liver; the latest research in experimental hepatotoxicology; the hepatotoxic risks of household, industrial, and environmental chemicals; and the adverse effects of drugs on the liver. This thoroughly revised, updated Second Edition features a greatly expanded section on the wide variety of drugs that can cause liver injury. For quick reference, an appendix lists these medications and their associated hepatic injuries. Also included are in-depth discussions of drug metabolism and factors affecting susceptibility to liver injury.

Survey of Antimalarial Agents

Survey of Antimalarial Agents
Author: George Robert Coatney
Publsiher: Unknown
Total Pages: 323
Release: 1953
ISBN 10:
ISBN 13: CORNELL:31924018502942
Language: EN, FR, DE, ES & NL

Survey of Antimalarial Agents Book Review:

Saving Lives Buying Time

Saving Lives  Buying Time
Author: Institute of Medicine,Board on Global Health,Committee on the Economics of Antimalarial Drugs
Publsiher: National Academies Press
Total Pages: 384
Release: 2004-10-09
ISBN 10: 0309092183
ISBN 13: 9780309092180
Language: EN, FR, DE, ES & NL

Saving Lives Buying Time Book Review:

For more than 50 years, low-cost antimalarial drugs silently saved millions of lives and cured billions of debilitating infections. Today, however, these drugs no longer work against the deadliest form of malaria that exists throughout the world. Malaria deaths in sub-Saharan Africaâ€"currently just over one million per yearâ€"are rising because of increased resistance to the old, inexpensive drugs. Although effective new drugs called “artemisinins†are available, they are unaffordable for the majority of the affected population, even at a cost of one dollar per course. Saving Lives, Buying Time: Economics of Malaria Drugs in an Age of Resistance examines the history of malaria treatments, provides an overview of the current drug crisis, and offers recommendations on maximizing access to and effectiveness of antimalarial drugs. The book finds that most people in endemic countries will not have access to currently effective combination treatments, which should include an artemisinin, without financing from the global community. Without funding for effective treatment, malaria mortality could double over the next 10 to 20 years and transmission will intensify.

STERIC HINDRANCE AND SYNERGISM IN THE DESIGN OF ANTIMALARIAL AGENTS

STERIC HINDRANCE AND SYNERGISM IN THE DESIGN OF ANTIMALARIAL AGENTS
Author: DOUGLAS CLIFFORD MORRISON
Publsiher: Unknown
Total Pages: 68
Release: 1964
ISBN 10:
ISBN 13: UOM:39015032276696
Language: EN, FR, DE, ES & NL

STERIC HINDRANCE AND SYNERGISM IN THE DESIGN OF ANTIMALARIAL AGENTS Book Review:

Antimalarial Chemotherapy

Antimalarial Chemotherapy
Author: Philip J. Rosenthal
Publsiher: Springer Science & Business Media
Total Pages: 396
Release: 2001-04-01
ISBN 10: 1592591116
ISBN 13: 9781592591114
Language: EN, FR, DE, ES & NL

Antimalarial Chemotherapy Book Review:

Philip Rosenthal, MD, and a panel of leading malaria experts drawn from academia, the military, and international health organizations survey the latest scientific understanding of antimalarial chemotherapy, emphasizing the molecular mechanisms of resistance and the description of important new targets. Their survey covers the current status of malarial and antimalarial chemotherapy, the relevant biology and biochemistry of malaria parasites, the antimalarial drugs currently available, new chemical approaches to chemotherapy, and possible new targets for chemotherapy. Comprehensive and cutting-edge, Antimalarial Chemotherapy: Mechanisms of Action, Resistance, and New Directions in Drug Discovery clearly delineates all the basic and clinical research now addressing one of the world's major unresolved disease problems, work that is now powerfully driving the rapid pace of antimalarial drug discovery today.

Exam Prep for Antimalarial Agents Chemistry And

Exam Prep for  Antimalarial Agents  Chemistry And
Author: Anonim
Publsiher: Unknown
Total Pages: 329
Release: 2021
ISBN 10:
ISBN 13:
Language: EN, FR, DE, ES & NL

Exam Prep for Antimalarial Agents Chemistry And Book Review:

An Overview of Tropical Diseases

An Overview of Tropical Diseases
Author: Amidou Samie
Publsiher: BoD – Books on Demand
Total Pages: 212
Release: 2015-12-02
ISBN 10: 953512224X
ISBN 13: 9789535122241
Language: EN, FR, DE, ES & NL

An Overview of Tropical Diseases Book Review:

Tropical diseases affect millions of people throughout the world and particularly in the developing countries. The millennium development goals had specifically targeted HIV/AIDS and Malaria for substantial reduction as well as Tuberculosis while many other tropical diseases have been neglected. The new sustainable development goals have not made such distinction and have targeted all diseases for elimination for the improvement of the quality of life of human beings on earth. The present book was developed to provide an update on issues relevant to the treatment of selected tropical diseases such as tuberculosis, malaria, leishmaniasis, schistosomiasis and ectoparasites such as chiggers which are widely distributed throughout the world. The control of these infections has been hampered by the development of drug resistance and the lack of the development of new and more effective drugs. The understanding of the biochemical processes underlying drug activity is therefore essential for the potential elimination of these infections.

Guidelines for the Treatment of Malaria

Guidelines for the Treatment of Malaria
Author: World Health Organization
Publsiher: World Health Organization
Total Pages: 194
Release: 2010
ISBN 10: 9241547928
ISBN 13: 9789241547925
Language: EN, FR, DE, ES & NL

Guidelines for the Treatment of Malaria Book Review:

"The purpose of this document is to provide comprehensible, global, evidence-based guidelines to help formulate policies and protocols for the treatment of malaria. Information is presented on the treatment of uncomplicated malaria, including disease in special groups (young children, pregnant women, people who are HIV positive, travellers from non-malaria endemic regions) and in complex emergency situations and severe malaria."--Publisher's description.

From Artemisia Annua L to Artemisinins Hindi Edition

From Artemisia Annua L  to Artemisinins  Hindi Edition
Author: Youyou Tu
Publsiher: Royal Collins Publishing Company
Total Pages: 456
Release: 2021-10-31
ISBN 10: 9781487804459
ISBN 13: 1487804458
Language: EN, FR, DE, ES & NL

From Artemisia Annua L to Artemisinins Hindi Edition Book Review:

From Artemisia annua L. to Artemisinins: The Discovery and Development of Artemisinins and Antimalarial Agents is the first book that systematically introduces the origin and development of artemisinine and artemisinine-based drugs. It includes four distinct sections, including Artemisia annua L., Artemisinin, Dihydroartemisinin, and other artemisinin derivatives. Tu Youyou, the chief inventor of artemisinin, together with other members from the research team, have written a book that will be a valuable reference work for both researchers involved in the medical industry and scholars who are interested in undertaking innovative research.

Antimalarial Agents An Update on Synthetic Variants of Chloroquine

Antimalarial Agents  An Update on Synthetic Variants of Chloroquine
Author: Anupama Parate
Publsiher: Unknown
Total Pages: 329
Release: 2019
ISBN 10: 9783659876677
ISBN 13: 3659876674
Language: EN, FR, DE, ES & NL

Antimalarial Agents An Update on Synthetic Variants of Chloroquine Book Review:

Malaria

Malaria
Author: Institute of Medicine,Division of International Health,Committee for the Study on Malaria Prevention and Control
Publsiher: National Academies Press
Total Pages: 328
Release: 1991-02-01
ISBN 10: 0309045274
ISBN 13: 9780309045278
Language: EN, FR, DE, ES & NL

Malaria Book Review:

Malaria is making a dramatic comeback in the world. The disease is the foremost health challenge in Africa south of the Sahara, and people traveling to malarious areas are at increased risk of malaria-related sickness and death. This book examines the prospects for bringing malaria under control, with specific recommendations for U.S. policy, directions for research and program funding, and appropriate roles for federal and international agencies and the medical and public health communities. The volume reports on the current status of malaria research, prevention, and control efforts worldwide. The authors present study results and commentary on the: Nature, clinical manifestations, diagnosis, and epidemiology of malaria. Biology of the malaria parasite and its vector. Prospects for developing malaria vaccines and improved treatments. Economic, social, and behavioral factors in malaria control.

Tandem Mass Spectrometry

Tandem Mass Spectrometry
Author: Ana Varela Coelho,Catarina De Matos Ferraz Franco
Publsiher: BoD – Books on Demand
Total Pages: 206
Release: 2013-05-29
ISBN 10: 9535111361
ISBN 13: 9789535111368
Language: EN, FR, DE, ES & NL

Tandem Mass Spectrometry Book Review:

Tandem Mass Spectrometry - Molecular Characterization presents a comprehensive coverage of theory, instrumentation and description of experimental strategies and MS/MS data interpretation for the structural characterization of relevant molecular compounds. The areas covered include the analysis of drugs, metabolites, carbohydrates and protein post-translational modifications. The book series in Tandem Mass Spectrometry serves multiple groups of audiences; professional (academic and industry), graduate students and general readers interested in the use of modern mass spectrometry in solving critical questions of chemical and biological sciences.

Artemisia

Artemisia
Author: Colin W. Wright
Publsiher: CRC Press
Total Pages: 344
Release: 2001-10-18
ISBN 10: 0203303067
ISBN 13: 9780203303061
Language: EN, FR, DE, ES & NL

Artemisia Book Review:

A comprehensive overview of this genus, Artemisia examines all aspects of the herbs uses and applications, its mode of action and clinical importance. Following a comprehensive introduction to the genus, the book discusses the botanical, phytochemical and biological aspects of a number of important species of Artemisis. Considering that the discove

Current Topics in Malaria

Current Topics in Malaria
Author: Alfonso J. Rodriguez-Morales
Publsiher: Unknown
Total Pages: 506
Release: 2016-11-30
ISBN 10: 9535127896
ISBN 13: 9789535127895
Language: EN, FR, DE, ES & NL

Current Topics in Malaria Book Review:

Medicinal Chemistry and Drug Discovery Chemotherapeutic agents

Medicinal Chemistry and Drug Discovery  Chemotherapeutic agents
Author: Alfred Burger
Publsiher: Unknown
Total Pages: 329
Release: 2003
ISBN 10:
ISBN 13: UOM:39015056276903
Language: EN, FR, DE, ES & NL

Medicinal Chemistry and Drug Discovery Chemotherapeutic agents Book Review:

The Potential of Plants as a Source of Antimalarial Agents

The Potential of Plants as a Source of Antimalarial Agents
Author: Geoffrey Rukunga,Tanzania. Wizara ya Afya na Ustawi wa Jamii
Publsiher: Unknown
Total Pages: 72
Release: 2006
ISBN 10: 9783981092905
ISBN 13: 3981092902
Language: EN, FR, DE, ES & NL

The Potential of Plants as a Source of Antimalarial Agents Book Review:

CDC Yellow Book 2018 Health Information for International Travel

CDC Yellow Book 2018  Health Information for International Travel
Author: Centers for Disease Control and Prevention CDC
Publsiher: Oxford University Press
Total Pages: 672
Release: 2017-04-17
ISBN 10: 0190628634
ISBN 13: 9780190628635
Language: EN, FR, DE, ES & NL

CDC Yellow Book 2018 Health Information for International Travel Book Review:

THE ESSENTIAL WORK IN TRAVEL MEDICINE -- NOW COMPLETELY UPDATED FOR 2018 As unprecedented numbers of travelers cross international borders each day, the need for up-to-date, practical information about the health challenges posed by travel has never been greater. For both international travelers and the health professionals who care for them, the CDC Yellow Book 2018: Health Information for International Travel is the definitive guide to staying safe and healthy anywhere in the world. The fully revised and updated 2018 edition codifies the U.S. government's most current health guidelines and information for international travelers, including pretravel vaccine recommendations, destination-specific health advice, and easy-to-reference maps, tables, and charts. The 2018 Yellow Book also addresses the needs of specific types of travelers, with dedicated sections on: · Precautions for pregnant travelers, immunocompromised travelers, and travelers with disabilities · Special considerations for newly arrived adoptees, immigrants, and refugees · Practical tips for last-minute or resource-limited travelers · Advice for air crews, humanitarian workers, missionaries, and others who provide care and support overseas Authored by a team of the world's most esteemed travel medicine experts, the Yellow Book is an essential resource for travelers -- and the clinicians overseeing their care -- at home and abroad.

Artemisinin Based and Other Antimalarials

Artemisinin Based and Other Antimalarials
Author: Guoqiao Li,Ying Li,Zelin Li,Meiyi Zeng
Publsiher: Academic Press
Total Pages: 736
Release: 2017-11-28
ISBN 10: 0128132116
ISBN 13: 9780128132111
Language: EN, FR, DE, ES & NL

Artemisinin Based and Other Antimalarials Book Review:

Artemisinin-Based and Other Antimalarials: Detailed Account of Studies by Chinese Scientists Who Discovered and Developed Them provides a historical and scientific background of the discovery and development of artemisinin, artemisinin derivatives, combination drugs and related chemicals. It is a historical document, a scientific treatise, and a fascinating description of innovative research on new drug development that is carried out under extremely difficult conditions. The book also includes detailed experiments, physical-chemical procedures, practical methodologies and clinical trials. It is a valuable reference for students and researchers in the fields of scientific history, medicine, pharmaceutical science, chemistry, pharmacology and toxicology. Presents details of all stages of drug development, including in vitro experiment, animal exploratory studies, animal tests for toxicity, safety and efficacy followed by stages I, II, III and IV, safety and efficacy in human volunteers and patients with malaria Provides many physical-chemical laboratory procedures, such as NMR, MS, HPLC and X-ray diffraction used in drug development Includes practical methodology of clinical trials from many research centers and countries to demonstrate the importance of this discovery