Advanced Neuro MR Techniques and Applications

Over the last decade, some of the greatest achievements in the field of neuroimaging have been related to remarkable advances in magnetic resonance techniques, including diffusion, perfusion, magnetic resonance spectroscopy, and functional MRI. Such techniques have provided valuable insights into tissue microstructure, microvasculature, metabolism and brain connectivity. Previously available mostly in research environments, these techniques are now becoming part of everyday clinical practice in a plethora of clinical MR systems. Nevertheless, despite growing interest and wider acceptance, there remains a lack of a comprehensive body of knowledge on the subject, exploring the intrinsic complexity and physical difficulty of the techniques. This book focuses on the basic principles and theories of diffusion, perfusion, magnetic resonance spectroscopy, and functional MRI. It also explores their clinical applications and places emphasis on the associated artifacts and pitfalls with a comprehensive and didactic approach. This book aims to bridge the gap between research applications and clinical practice. It will serve as an educational manual for neuroimaging researchers and radiologists, neurologists, neurosurgeons, and physicists with an interest in advanced MR techniques. It will also be a useful reference text for experienced clinical scientists who wish to optimize their multi-parametric imaging approach.

"This book includes state-of-the-art methodologies that introduce biomedical imaging in decision support systems and their applications in clinical practice"--Provided by publisher.

The field of brain imaging is developing at a rapid pace and has greatly advanced the areas of cognitive and clinical neuroscience. The availability of neuroimaging techniques, especially magnetic resonance imaging (MRI), functional MRI (fMRI), diffusion tensor imaging (DTI) and magnetoencephalography (MEG) and magnetic source imaging (MSI) has brought about breakthroughs in neuroscience.To obtain comprehensive information about the activity of the human brain, different analytical approaches should be complemented. Thus, in "intermodal multimodality" imaging, great efforts have been made to combine the highest spatial resolution (MRI, fMRI) with the best temporal resolution (MEG or EEG). "Intramodal multimodality" imaging combines various functional MRI techniques (e.g., fMRI, DTI, and/or morphometric/volumetric analysis). The multimodal approach is conceptually based on the combination of different noninvasive functional neuroimaging tools, their registration and cointegration. In particular, the combination of imaging applications that map different functional systems is useful, such as fMRI as a technique for the localization of cortical function and DTI as a technique for mapping of white matter fiber bundles or tracts.This booklet gives an insight into the wide field of multimodal imaging with respect to concepts, data acquisition, and postprocessing. Examples for intermodal and intramodal multimodality imaging are also demonstrated.Table of Contents: Introduction / Neurological Measurement Techniques and First Steps of Postprocessing / Coordinate Transformation / Examples for Multimodal Imaging / Clinical Aspects of Multimodal Imaging / References / Biography

This book constitutes the thoroughly refereed proceedings of the 16th International Conference on Knowledge-Based Intelligent Information and Engineering Systems, KES 2012, held in San Sebastian, Spain, in September 2012. The 21 revised papers were carefully reviewed and selected from 254 submissions. Topics of interest include the exploitation of AI techniques, most recent research in information technologies and dynamic ontologies.

Part of the Oxford Textbooks in Clinical Neurology series, the Oxford Textbook of Neuroimaging provides an overview of the established and latest neuroimaging methodologies, and illustrates their application to the main diseases of the brain and the spinal cord including movement disorders, headache and stroke. In addition, assessments of neuroimaging techniques in both adult and paediatric neurological conditions are included, enabling thorough examples from both age groups. This full-colour book contains 280 detailed photographs and illustrations that enable a clear understanding of each technique. Covering the newest advances, each different imagining technique is comprehensively described, providing a practical relevance and a stimulus for more in-depth readings. The print edition is supplemented with a concurrent online edition, which allows access to the full content of the textbook, contains links from the references to primary research journal articles, and provides access to figures and tables that can be downloaded by the user. Providing a balanced state-of-the-art guide to neuroimaging for neurologists and radiologists, this title will enhance understanding of the pathophysiological basis of neurological conditions and will help set the stage for future research.

Medical imaging is an important topic and plays a key role in robust diagnosis and patient care. It has experienced an explosive growth over the last few years due to imaging modalities such as X-rays, computed tomography (CT), magnetic resonance (MR) imaging, and ultrasound. This book focuses primarily on model-based segmentation techniques, which are applied to cardiac, brain, breast and microscopic cancer cell imaging. It includes contributions from authors working in industry and academia, and presents new material.

This concise and comprehensive review uniquely contains all the information required to perform and interpret clinical MR perfusion imaging.

This issue of MRI Clinics of North America focuses on Advanced MR Techniques for Imaging the Abdomen and Pelvis and is edited by Dr. Sudhakar Venkatesh. Articles will include: Advances in MR Elastography in Liver; Biliary Tract Imaging; Imaging of the Pancreas; PET/MRI Applications in Abdomen and Pelvis; Abbreviated MR Protocols for the Abdomen and Pelvis; Advances in MR Angiography of Abdomen and Pelvis; Advances in MRI of Prostate; Advances in MRI of the Female Pelvis; Advanced MR Techniques for Imaging the Abdomen and Pelvis; Texture Analysis and AI with MR in Abdomen and Pelvis; Advances in MRI of the Kidneys and Upper Urinary Tract, and more!

The brain is the most complex computational device we know, consisting of highly interacting and redundant networks of areas, supporting specific brain functions. The rules by which these areas organize themselves to perform specific computations have only now started to be uncovered. Advances in non-invasive neuroimaging technologies have revolutionized our understanding of the functional anatomy of cortical circuits in health and disease states, which is the focus of this book. The first section of this book focuses on methodological issues, such as combining functional MRI technology with other brain imaging modalities. The second section examines the application of brain neuroimaging to understand cognitive, visual, auditory, motor and decision-making networks, as well as neurological diseases. The use of non-invasive neuroimaging technologies will continue to stimulate an exponential growth in understanding basic brain processes, largely as a result of sustained advances in neuroimaging methods and applications.

Information for neuroimaging specialists includes a "Diagnostic Checklist or “Clinical Recommendations along with tables presenting recommended MR sequences and protocols. The primary focus of the issue is 3.0T; one article specifically deals with 7T and higher fields are mentioned sporadically throughout. Topics include: Tumor High-Field MR; Stroke High-Field MR; High-Field MR of Inflammation; Vascular Disorders: MR Angiography of Brain Vessels, MR Angiography of Neck Vessels, and Perfusion Imaging; Plaque Imaging; Neurodegenerative Disease; Epilepsy Imaging; Head and Neck Oncology Applications; Pediatric High-Field Imaging; Spine High-Field Imaging; Ultra High-Field Imaging; Future Perspectives on High-Field MR

Concise yet comprehensive, Clinical Neurology, Fourth Edition builds on the success of three previous editions in helping medical students, junior doctors, and practicing physicians acquire an improved understanding of the principles of neurology. The fourth edition has been fully revised and updated to take into account current developments in the investigation and treatment of neurological disorders. It retains a clinical focus, emphasizing the basic skills of history taking and neurological examination throughout. This edition presents expanded coverage of neurophysiology and motor neurone disease. Authored and edited by leading figures in neurology, this book is an indispensable introduction to the field of clinical neurology, for use in training and study as well as in the clinical setting.

Basic relevant information on methodologies used in neurological disease models can be extremely hard to find. Originally published in 2006, this important reference work contains 30 chapters from over 60 internationally recognized scientists and covers every major methodology and disease model used in neuroscience research. Divided into two major sections, the first deals with general methodologies in neuroscience research covering topics from animal welfare and ethical issues to surgical procedures, post-operative care and behavioral testing. Section two covers every major disease model including traumatic brain injury, ischemia and stroke, to Parkinson's, motor neurone disease, epilepsy and sleep disorders. Delivering critical methodological information and describing small animal models for almost all major neurological diseases, this book forms an essential reference for anyone working in neuroscience, from beginning students to experienced researchers and medical professionals.

Covers each physiological MR methodology and their applications to all major neurological diseases.

Written by Lane F. Donnelly, MD, recipient of the Society of Pediatric Radiology’s 2009 Singleton-Taybi Award for professional lifetime dedication to medical education, "Pediatric Imaging: The Fundamentals" makes it remarkably simple to learn how to safely perform and accurately interpret pediatric imaging studies. Ideal for residents and practitioners alike, this reader-friendly text emphasizes advanced imaging applications—including neuro applications—while nearly 400 high-quality, clinically relevant digital images (nearly 100 in color) clearly demonstrate essential concepts, techniques, and interpretation skills. Full-chapter coverage of current breakthroughs in PET/CT, MR sleep studies, fetal imaging, and more, ensure that you have the latest information available at your fingertips. Offers full-chapter coverage of current breakthroughs in PET/CT, MR sleep studies, fetal imaging, and more, ensuring that you have the latest information at your fingertips. Emphasizes advanced imaging applications, including neuro applications. Highlights the basic anatomy needed to understand this complex subspecialty. Provides an in-depth discussion of patient safety issues to help you gain a basic understanding of radiology and its effect on the pediatric patient. Presents information in a reader-friendly format through lists, tables, and images that makes reference quick and easy. Includes nearly 650 high-quality, clinically relevant digital images that clearly demonstrate essential concepts, techniques, and interpretation skills.

This book provides an overview of the practical aspects of diffusion tensor imaging (DTI), from understanding the basis of the technique through selection of the right protocols, trouble-shooting data quality, and analyzing DTI data optimally. DTI is a non-invasive magnetic resonance imaging (MRI) technique for visualizing and quantifying tissue microstructure based on diffusion. The book discusses the theoretical background underlying DTI and advanced techniques based on higher-order models and multi-shell diffusion imaging. It covers the practical implementation of DTI; derivation of information from DTI data; and a range of clinical applications, including neurosurgical planning and the assessment of brain tumors. Its practical utility is enhanced by decision schemes and a fully annotated DTI brain atlas, including color fractional anisotropy maps and 3D tractography reconstructions of major white matter fiber bundles. Featuring contributions from leading specialists in the field of DTI, Diffusion Tensor Imaging: A Practical Handbook is a valuable resource for radiologists, neuroradiologists, MRI technicians and clinicians.

Editor Jay J. Pillai and authors review important areas in Clinical Applications of Functional MRI. Articles will include: Blood Oxygen Level Dependent Functional Magnetic Resonance Imaging for Presurgical Planning; Visual Mapping Using Blood Oxygen Level Dependent Functional MRI; Applications of BOLD fMRI and DTI in Epilepsy; Pretherapeutic fMRI in Children; BOLD fMRI for Presurgical Planning; Brain Tensor Imaging for Brain Malformations: Does it Help?; Technical Considerations for fMRI Analysis; Special Considerations/Technical Limitations of BOLD fMRI; The Economics of Functional MRI: Clinical and Research; Memory Assessment in the Clinical Context Using fMRI: A Critical Look at the State of the Field; Resting State BOLD fMRI for Pre-surgical Planning, and more!

Functional Neuroradiology: Principles and Clinical Applications, is a follow-up to Faro and Mohamed’s groundbreaking work, Functional (BOLD)MRI: Basic Principles and Clinical Applications. This new 49 chapter textbook is comprehensive and offers a complete introduction to the state-of-the-art functional imaging in Neuroradiology, including the physical principles and clinical applications of Diffusion, Perfusion, Permeability, MR spectroscopy, Positron Emission Tomography, BOLD fMRI and Diffusion Tensor Imaging. With chapters written by internationally distinguished neuroradiologists, neurologists, psychiatrists, cognitive neuroscientists, and physicists, Functional Neuroradiology is divided into 9 major sections, including: Physical principles of all key functional techniques, Lesion characterization using Diffusion, Perfusion, Permeability, MR spectroscopy, and Positron Emission Tomography, an overview of BOLD fMRI physical principles and key concepts, including scanning methodologies, experimental research design, data analysis, and functional connectivity, Eloquent Cortex and White matter localization using BOLD fMRI and Diffusion Tensor Imaging, Clinical applications of BOLD fMRI in Neurosurgery, Neurology, Psychiatry, Neuropsychology, and Neuropharmacology, Multi-modality functional Neuroradiology, Beyond Proton Imaging, Functional spine and CSF imaging, a full-color Neuroanatomical Brain atlas of eloquent cortex and key white matter tracts and BOLD fMRI paradigms. By offering readers a complete overview of functional imaging modalities and techniques currently used in patient diagnosis and management, as well as emerging technology, Functional Neuroradiology is a vital information source for physicians and cognitive neuroscientists involved in daily practice and research.

ìBy far, the most comprehensive and detailed coverage of pediatric neuropsychology available in a single book today, Davis provides coverage of basic principles of pediatric neuropsychology, but overall the work highlights applications to daily practice and special problems encountered by the pediatric neuropsychologist.î Cecil R. Reynolds, PhD Texas A&M University "The breadth and depth of this body of work is impressive. Chapters written by some of the best researchers and authors in the field of pediatric neuropsychology address every possible perspective on brain-behavior relationships culminating in an encyclopedic textÖ. This [book] reflects how far and wide pediatric neuropsychology has come in the past 20 years and the promise of how far it will go in the next." Elaine Fletcher-Janzen, EdD, NCSP, ABPdN The Chicago School of Professional Psychology "...it would be hard to imagine a clinical situation in pediatric neuropsychology in whichthis book would fail as a valuable resource."--Archives of Clinical Neuropsychology "I believe there is much to recommend this hefty volume. It is a solid reference that I can see appreciating as a resource as I update my training bibliography."--Journal of the International Neuropsychological Society This landmark reference covers all aspects of pediatric neuropsychology from a research-based perspective, while presenting an applied focus with practical suggestions and guidelines for clinical practice. Useful both as a training manual for graduate students and as a comprehensive reference for experienced practitioners, it is an essential resource for those dealing with a pediatric population. This handbook provides an extensive overview of the most common medical conditions that neuropsychologists encounter while dealing with pediatric populations. It also discusses school-based issues such as special education law, consulting with school staff, and reintegrating children back into mainstream schools. It contains over 100 well-respected authors who are leading researchers in their respective fields. Additionally, each of the 95 chapters includes an up-to-date review of available research, resulting in the most comprehensive text on pediatric neuropsychology available in a single volume. Key Features: Provides thorough information on understanding functional neuroanatomy and development, and on using functional neuroimaging Highlights clinical practice issues, such as legal and ethical decision-making, dealing with child abuse and neglect, and working with school staff Describes a variety of professional issues that neuropsychologists must confront during their daily practice, such as ethics, multiculturalism, child abuse, forensics, and psychopharmacology

Each issue includes separate but continuously paged sections called: Nuclear medicine, and: Ultrasound