A Pharmacology Primer

A Pharmacology Primer
Author: Terry Kenakin
Publsiher: Academic Press
Total Pages: 430
Release: 2014
ISBN 10: 9780124076631
ISBN 13: 0124076637
Language: EN, FR, DE, ES & NL

A Pharmacology Primer Book Review:

A Pharmacology Primer: Techniques for More Effective and Strategic Drug Discovery, 4th Edition features the latest ideas and research about the application of pharmacology to the process of drug discovery to equip readers with a deeper understanding of the complex and rapid changes in this field. Written by well-respected pharmacologist, Terry P. Kenakin, this primer is an indispensable resource for all those involved in drug discovery. This edition has been thoroughly revised to include material on data-driven drug discovery, biased signaling, structure-based drug design, drug activity screening, drug development (including pharmacokinetics and safety Pharmacology), and much more. With more color illustrations, examples, and exercises throughout, this book remains a top reference for all industry and academic scientists and students directly involved in drug discovery, or pharmacologic research. Highlights changes surrounding the strategy of drug discovery to provide you with a comprehensive reference featuring advances in the methods involved in lead optimization and more effective drug discovery Includes a new chapter on data-driven drug discovery in terms of the optimal design of pharmacological experiments to identify mechanism of action of new molecules Illustrates the application of rapid inexpensive assays to predict activity in the therapeutic setting, showing data outcomes and the limitations inherent in interpreting this data

A Pharmacology Primer

A Pharmacology Primer
Author: Terry Kenakin
Publsiher: Elsevier
Total Pages: 318
Release: 2010-07-26
ISBN 10: 9780080465302
ISBN 13: 0080465307
Language: EN, FR, DE, ES & NL

A Pharmacology Primer Book Review:

The Second Edition will continue this tradition of better preparing researchers in the basics of pharmacology. In addition, new human interest material including historical facts in pharmacology will be added. A new section on therapeutics will help readers identify with diseases and drug treatments. Over 30 new figures and tables More human interest information to provide readers with historical facts on pharmacology research New section on therapeutics to help identify diseaes and drug treatments New section on new biological concepts relevant to pharmacological research (i.e., systems biology) New study sections organized with ASPET and other international pharmacology organizations New coverage of pharmacokinetics and drug disposition

A Pharmacology Primer

A Pharmacology Primer
Author: Terry Kenakin
Publsiher: Academic Press
Total Pages: 488
Release: 2018-10-26
ISBN 10: 0128139587
ISBN 13: 9780128139585
Language: EN, FR, DE, ES & NL

A Pharmacology Primer Book Review:

A Pharmacology Primer: Techniques for More Effective and Strategic Drug Discovery, Fifth Edition features the latest ideas and research regarding the application of pharmacology to the process of drug discovery. Written by well-respected pharmacologist, Terry P. Kenakin, this primer is an indispensable resource for all those involved in drug discovery. This updated edition has been thoroughly revised to include material on quantifying drug efficacy through bias and cluster analysis, the impact of molecular dynamics and protein structural analysis, the real time kinetic analysis of drug effect, virtual screening for new drug chemical scaffolds, and much more. With full color illustrations and new examples throughout, this book remains a top reference for all industry and academic scientists that is also ideal for students directly involved in drug discovery or pharmacologic research. Highlights changes surrounding strategies for drug discovery, providing a comprehensive reference and featuring advances in the methods involved Includes multiple new sections, such as development and utilization of models in pharmacology, de-orphanization of new drug targets, predicting impact of disease on drug pharmacokinetics, and the impact of enzyme kinetics on drug-drug interactions Illustrates the application of rapid inexpensive assays to predict activity in the therapeutic setting, showing data outcomes and the limitations inherent in interpreting this data

A Pharmacology Primer

A Pharmacology Primer
Author: Terry Kenakin
Publsiher: Academic Press
Total Pages: 416
Release: 2009-02-07
ISBN 10: 9780080923338
ISBN 13: 008092333X
Language: EN, FR, DE, ES & NL

A Pharmacology Primer Book Review:

This successful guide assists scientists trained in molecular biology and related fields who now need to know the basic theories, principles and practical applications of pharmacology. This latest edition continues the tradition of better preparing researchers in the basics of pharmacology. With expanded hands-on exercises and the addition of Pharmacokinetics coverage, new human interest material including historical facts in pharmacology and a new section on therapeutics that will help readers identify with diseases and drug treatments. The ideal book for researchers in drug discovery who have seen their role shift from "individual" to "team player" where that team includes chemists, biologists, and others with strong, but varied, science backgrounds who must now work together toward their common pharmacology goal. At GlaxoSmithKline, a pharmaceuticals world-leader, Terry Kenakin regularly teaches a course for their research scientists and has drawn on his experience to create a pharmacology primer. *New - Latest coverage of the chemistry of drugs including expanded coverage of the pharmacokinetic discussion of druglike properties -- Increases reader understanding of necessary ADME (Absorption, Distribution, Metabolism, and Excretion) properties and increases the rate of drug approval and acceptance. *Context - Unique discussions on various drug discovery teams and the role of the chemist on those teams -- Promotes the understanding of these expanding roles and responsibilities and how to maximize the effective contributions of each matrix team member. *Real-world learning - There are hands-on exercises, with extensive answers, utilizing real data on structure activity relationships; utilization of pharmacological principles to make general statements about how changes in structure lead to changes in drug activity. + hands on exercises with extensive answers on Pharmacokinetics -- Stengthens practical application and understanding of core concepts and principles. *Study sections are organized with ASPET (American Society for Pharmacology and Experimental Therapeutics)and other international organizations -- Ensures that learning follows professional industry standards.

Medication Workbook for Pharmacy Technicians A Pharmacology Primer

Medication Workbook for Pharmacy Technicians  A Pharmacology Primer
Author: David R. Bright,Mary F. Powers
Publsiher: Morton Publishing Company
Total Pages: 360
Release: 2012-01-01
ISBN 10: 1617310905
ISBN 13: 9781617310904
Language: EN, FR, DE, ES & NL

Medication Workbook for Pharmacy Technicians A Pharmacology Primer Book Review:

Officially endorsed by the American Pharmacists Association (APhA), this practical workbook provides a basic introduction to pharmacology and reinforces the use of medications for prospective technicians to work in a pharmacy and to help prepare them for the pharmacy technician national certification exams.

A Primer of Drug Action

A Primer of Drug Action
Author: Robert M. Julien, Ph.D.
Publsiher: Holt Paperbacks
Total Pages: 512
Release: 2013-08-06
ISBN 10: 146685118X
ISBN 13: 9781466851184
Language: EN, FR, DE, ES & NL

A Primer of Drug Action Book Review:

Since 1975, Robert Julien's A Primer of Drug Action has been the definitive guide to the effects of psychoactive drugs on the brain and on behavior. Now fully updated, this popular guide continues to lead the way through a rapidly changing field, providing readers with a clear, contemporary, and objective look at every drug and medication that either positively or adversely affects brain function. This edition includes important new information on -Herbal medications -Drug therapy for behavioral and anxiety disorders -Clinical practice guidelines for treating psychological disorders -Depression and the action of antidepressant drugs -The use of newer anticonvulsants in the treatment of bipolar disorder, pain syndromes, and behavioral disorders -Drug therapy for children, adolescents and the elderly -"New generation" antipsychotic agents Authoritative, comprehensive, and suitable for those with little background in biology, A Primer of Drug Action is an indispensable source of information for anyone interested in drug use, abuse, and education.

Elements of Pharmacology

Elements of Pharmacology
Author: P. J. Bentley
Publsiher: Cambridge University Press
Total Pages: 154
Release: 1981-08-31
ISBN 10: 9780521280747
ISBN 13: 0521280745
Language: EN, FR, DE, ES & NL

Elements of Pharmacology Book Review:

Written primarily for students of medicine, pharmacy, and pharmacology, this introductory book provides a concise summary of the principles that underlie the science of pharmacology. It presents the basic concepts required for understanding the use, mechanisms of action, toxicity and side effects, and therapeutic application of drugs in man. Thus the book may also be of interest to medical practitioners and to biological and medical scientists. Among topics covered are the sources of drugs, the way they are administered and dealt with in the body, as well as concepts about the nature of their actions. The last include their chemical interactions with components of cells and the manner in which these lead to therapeutically desirable as well as undesirable and even toxic effects. In addition, clinically related subjects, such as drug interactions, teratogenic and carcinogenic effects are discussed. The development and testing of new drugs are also described. For easy reference, at the back of the book there is a glossary of drugs named in the text.

Essential Pharmacokinetics

Essential Pharmacokinetics
Author: Thorsteinn Loftsson
Publsiher: Academic Press
Total Pages: 178
Release: 2015-03-25
ISBN 10: 0128014911
ISBN 13: 9780128014912
Language: EN, FR, DE, ES & NL

Essential Pharmacokinetics Book Review:

Essential Pharmacokinetics: A Primer for Pharmaceutical Scientists is an introduction to the concepts of pharmacokinetics intended for graduate students and new researchers working in the pharmaceutical sciences. This book describes the mathematics used in the mammillary model as well as the application of pharmacokinetics to pharmaceutical product development, and is useful as both a self-study and classroom resource. Content coverage includes detailed discussions of common models and important pharmacokinetic concepts such as biological half-life, clearance, excretion, multiple dosage regimens and more. Numerous equations, practical examples and figures are incorporated to clearly illustrate the theoretical background of pharmacokinetic behavior of drugs and excipients. Shows how to apply basic pharmacokinetic methods to evaluate drugs, excipients and drug products Uses guided practice questions, mathematical concepts and real-world examples for self-assessment and retention purposes Illustrates how to write and evaluate drug registration files

Pharmacogenomics A Primer for Clinicians

Pharmacogenomics  A Primer for Clinicians
Author: Jerika T. Lam,Mary A Gutierrez
Publsiher: McGraw Hill Professional
Total Pages: 512
Release: 2020-12-22
ISBN 10: 1260457117
ISBN 13: 9781260457117
Language: EN, FR, DE, ES & NL

Pharmacogenomics A Primer for Clinicians Book Review:

An invaluable resource to the rapidly emerging field of pharmacogenomics—complete with case studies, clinical pearls, and treatment recommendations The aim of pharmacogenomics is to improve personalized medicine by taking into account how genes affect an individual’s tolerability and response to drugs. Approaching pharmacogenomics from the current clinical, scientific, and implementation perspectives, this guide serves as an invaluable evidence-based resource to the subject. Reflecting the shift from genetics to genomics in the pharmaceutical sphere, the book covers pharmacogenomics fundamentals; genotyping tests and evidence; clinical implementation; ethical, legal, and social issues; and more. You’ll also find illuminating case scenarios, clinical pearls, and evidence-based recommendations for treatments and alternatives based on CPIC, PharmGKB, and FDA guidelines.

Regenerative Pharmacology

Regenerative Pharmacology
Author: George J. Christ,Karl-Erik Andersson
Publsiher: Cambridge University Press
Total Pages: 329
Release: 2013-04-15
ISBN 10: 1107354730
ISBN 13: 9781107354739
Language: EN, FR, DE, ES & NL

Regenerative Pharmacology Book Review:

Regenerative medicine is broadly defined as the repair or replacement of damaged cells, tissues and organs. It is a multidisciplinary effort in which technologies derive from the fields of cell, developmental and molecular biology; chemical and material sciences (i.e. nanotechnology); engineering; surgery; transplantation; immunology; molecular genetics; physiology; and pharmacology. As regenerative medicine technologies continue to evolve and expand across the boundaries of numerous scientific disciplines, they remain at the forefront of the translational research frontier with the potential to radically alter the treatment of a wide variety of disease and dysfunction. This book will draw attention to the critical role that pharmacological sciences will undeniably play in the advancement of these treatments. This book is invaluable for advanced students, postdoctoral fellows, researchers new to the field of regenerative medicine/tissue engineering, and experienced investigators looking for new research avenues. The first state-of-the-art book in this rapidly evolving field of research.

Drug Discovery and Development E Book

Drug Discovery and Development   E Book
Author: Raymond G Hill
Publsiher: Elsevier Health Sciences
Total Pages: 368
Release: 2012-07-20
ISBN 10: 0702053163
ISBN 13: 9780702053160
Language: EN, FR, DE, ES & NL

Drug Discovery and Development E Book Book Review:

The modern pharmacopeia has enormous power to alleviate disease, and owes its existence almost entirely to the work of the pharmaceutical industry. This book provides an introduction to the way the industry goes about the discovery and development of new drugs. The first part gives a brief historical account from its origins in the mediaeval apothecaries’ trade, and discusses the changing understanding of what we mean by disease, and what therapy aims to achieve, as well as summarising case histories of the discovery and development of some important drugs. The second part focuses on the science and technology involved in the discovery process: the stages by which a promising new chemical entity is identified, from the starting point of a medical need and an idea for addressing it. A chapter on biopharmaceuticals, whose discovery and development tend to follow routes somewhat different from synthetic compounds, is included here, as well as accounts of patent issues that arise in the discovery phase, and a chapter on research management in this environment. The third section of the book deals with drug development: the work that has to be undertaken to turn the drug candidate that emerges from the discovery process into a product on the market. The definitive introduction to how a pharmaceutical company goes about its business of discovering and developing drugs. The second edition has a new editor: Professor Raymond Hill ● non-executive director of Addex Pharmaceuticals, Covagen and of Orexo AB ● Visiting Industrial Professor of Pharmacology in the University of Bristol ● Visiting Professor in the School of Medical and Health Sciences at the University of Surrey ● Visiting Professor in Physiology and Pharmacology at the University of Strathclyde ● President and Chair of the Council of the British Pharmacological Society ● member of the Nuffield Council on Bioethics and the Advisory Council on Misuse of Drugs. New to this edition: Completely rewritten chapter on The Role of Medicinal Chemistry in the Drug Discovery Process. New topic - DMPK Optimization Strategy in drug discovery. New chapter on Scaffolds: Small globular proteins as antibody substitutes. Totally updated chapters on Intellectual Property and Marketing 50 new illustrations in full colour Features Accessible, general guide to pharmaceutical research and development. Examines the interfaces between cost and social benefit, quality control and mass production, regulatory bodies, patent management, and all interdisciplinary intersections essential to effective drug development. Written by a strong team of scientists with long experience in the pharmaceutical industry. Solid overview of all the steps from lab bench to market in an easy-to-understand way which will be accessible to non-specialists. From customer reviews of the previous edition: ‘... it will have everything you need to know on this module. Deeply referenced and, thus, deeply reliable. Highly Commended in the medicine category of the BMA 2006 medical book competition Winner of the Royal Society of Medicine Library Prize for Medical Book of the Year

The Cult of Pharmacology

The Cult of Pharmacology
Author: Richard DeGrandpre
Publsiher: Duke University Press
Total Pages: 312
Release: 2006-11-06
ISBN 10: 0822388197
ISBN 13: 9780822388197
Language: EN, FR, DE, ES & NL

The Cult of Pharmacology Book Review:

America had a radically different relationship with drugs a century ago. Drug prohibitions were few, and while alcohol was considered a menace, the public regularly consumed substances that are widely demonized today. Heroin was marketed by Bayer Pharmaceuticals, and marijuana was available as a tincture of cannabis sold by Parke Davis and Company. Exploring how this rather benign relationship with psychoactive drugs was transformed into one of confusion and chaos, The Cult of Pharmacology tells the dramatic story of how, as one legal drug after another fell from grace, new pharmaceutical substances took their place. Whether Valium or OxyContin at the pharmacy, cocaine or meth purchased on the street, or alcohol and tobacco from the corner store, drugs and drug use proliferated in twentieth-century America despite an escalating war on “drugs.” Richard DeGrandpre, a past fellow of the National Institute on Drug Abuse and author of the best-selling book Ritalin Nation, delivers a remarkably original interpretation of drugs by examining the seductive but ill-fated belief that they are chemically predestined to be either good or evil. He argues that the determination to treat the medically sanctioned use of drugs such as Miltown or Seconal separately from the illicit use of substances like heroin or ecstasy has blinded America to how drugs are transformed by the manner in which a culture deals with them. Bringing forth a wealth of scientific research showing the powerful influence of social and psychological factors on how the brain is affected by drugs, DeGrandpre demonstrates that psychoactive substances are not angels or demons irrespective of why, how, or by whom they are used. The Cult of Pharmacology is a bold and necessary new account of America’s complex relationship with drugs.

Primer on Transplantation

Primer on Transplantation
Author: American Society of Transplantation
Publsiher: John Wiley & Sons
Total Pages: 368
Release: 2010-12-15
ISBN 10: 1444391763
ISBN 13: 9781444391763
Language: EN, FR, DE, ES & NL

Primer on Transplantation Book Review:

Produced in association with the American Society of Transplantation, this new edition is full of practical advice for the next generation of transplant professionals. In addition to 5 organ-specific chapters: kidney, pancreas, heart, lung and liver, the book includes essential information on: immunobiology pharmacology donor management infectious complications pediatric transplantation general principles of patient management Fully updated and redesigned to make it even more user-friendly, the book now contains clinical vignettes, key point boxes, and self-assessment multiple choice questions in each chapter. Primer on Transplantation, Third Edition is an invaluable resource for all health professionals in the transplant team including trainees, residents, fellows, physicians, surgeons, nurses and transplant co-ordinators. Purchasing this book entitles you to access to the companion website: www.astprimer.com The website includes: Interactive Multiple-Choice Questions for each chapter Figures from the book as Powerpoints for downloading All chapters online

Julien s Primer of Drug Action

Julien s Primer of Drug Action
Author: Claire D. Advokat,Robert Julien,Joseph Comaty
Publsiher: Worth
Total Pages: 672
Release: 2019-01-17
ISBN 10: 9781319248949
ISBN 13: 1319248942
Language: EN, FR, DE, ES & NL

Julien s Primer of Drug Action Book Review:

Julien’s Primer of Drug Action continues to evolve side by side with the field it covers providing a thoroughly up to date look at psychotherapeutic and recreational drugs, including the latest research and the newest formulations. The thoroughly updated 14th edition features: New coverage of opioids of abuse, and drugs used to treat of opioid dependence and opioid overdose New research on the use of marijuana to treat Alzheimers, PTSD, and Epilepsy New coverage of pharmacological, physiological, and psychoactive effects of synthetic marijuana including its toxicity New research on Cannabidiol (CBD) and its therapeutic uses New research of the efficacy of antipsychotics to treat dementia, Parkinson’s, bipolar, OCD, and PTSD The use of genetic testing to predict effectiveness of antidepressant treatment New research on the use of ketamine for the treatment of depression

Rowan s Primer of EEG E Book

Rowan s Primer of EEG E Book
Author: Lara V. Marcuse,Madeline C. Fields,Jiyeoun Jenna Yoo
Publsiher: Elsevier Health Sciences
Total Pages: 208
Release: 2015-09-22
ISBN 10: 0323358675
ISBN 13: 9780323358675
Language: EN, FR, DE, ES & NL

Rowan s Primer of EEG E Book Book Review:

The new edition of Rowan’s Primer of EEG continues to provide clear, concise guidance on the difficult technical aspects of how to perform and interpret EEGs. Practical yet brief, it is perfectly suited for students, residents, and neurologists alike, while included reference material will be continually useful, even to the experienced doctor. Features brief, to-the-point text with easily understandable language for quick reference. Portable design makes it simple to carry anywhere. Concise, reader-friendly format features improved 4-color design and online quiz-format assessment questions within each chapter. Includes the new nomenclature for EEGs put forth by the American Clinical Neurophysiology Society. Features a greater focus on pediatrics content and includes online videos detailing clinical descriptions of seizures and EEG interpretation. Delivers a concise chart of the EEG changes through the neonatal period. Offers enhanced coverage of epilepsy syndromes with a quick-access chart highlighting age of onset, prognosis, clinical characteristics, and EEG characteristics.

Good Research Practice in Non Clinical Pharmacology and Biomedicine

Good Research Practice in Non Clinical Pharmacology and Biomedicine
Author: Anton Bespalov,Martin C. Michel,Thomas Steckler
Publsiher: Springer Nature
Total Pages: 424
Release: 2020-01-01
ISBN 10: 3030336565
ISBN 13: 9783030336561
Language: EN, FR, DE, ES & NL

Good Research Practice in Non Clinical Pharmacology and Biomedicine Book Review:

This open access book, published under a CC BY 4.0 license in the Pubmed indexed book series Handbook of Experimental Pharmacology, provides up-to-date information on best practice to improve experimental design and quality of research in non-clinical pharmacology and biomedicine.

The Pharmacology Primer

The Pharmacology Primer
Author: Deluca
Publsiher: Unknown
Total Pages: 329
Release: 2012-11-01
ISBN 10: 9780763758202
ISBN 13: 0763758205
Language: EN, FR, DE, ES & NL

The Pharmacology Primer Book Review:

Fundamentals Of Experimental Pharmacology

Fundamentals Of Experimental Pharmacology
Author: Ghosh Mn
Publsiher: Unknown
Total Pages: 329
Release: 2021
ISBN 10: 9788190296502
ISBN 13: 8190296507
Language: EN, FR, DE, ES & NL

Fundamentals Of Experimental Pharmacology Book Review:

Essentials of Cardiac Anesthesia for Noncardiac Surgery E Book

Essentials of Cardiac Anesthesia for Noncardiac Surgery E Book
Author: Joel A. Kaplan
Publsiher: Elsevier Health Sciences
Total Pages: 796
Release: 2018-07-21
ISBN 10: 0323567126
ISBN 13: 9780323567121
Language: EN, FR, DE, ES & NL

Essentials of Cardiac Anesthesia for Noncardiac Surgery E Book Book Review:

Provides guidance on the anesthetic diagnosis and management of the full range of cardiac lesions, helping minimize adverse outcomes and reduce complications for patients with common, complex, or uncommon cardiac conditions. Includes complete coverage of echocardiography and current monitoring techniques needed for thorough perioperative assessment – all from the anesthesiologist’s perspective. Discusses safe and effective perioperative anesthetic management of patients presenting with advanced levels of cardiac care such as drug-eluting stents, multiple antiplatelet drugs, ventricular assist devices, multiple drugs for end-stage heart failure, and implanted electrical devices that produce cardiac resynchronization therapy, as well as patients with complicated obstetric problems or other significant cardiovascular issues. Features a concise, easy-to-navigate format and Key Points boxes in each chapter that help you find answers quickly. Provides guidance on the anesthetic diagnosis and management of the full range of cardiac lesions, helping minimize adverse outcomes and reduce complications for patients with common, complex, or uncommon cardiac conditions. Includes complete coverage of echocardiography and current monitoring techniques needed for thorough perioperative assessment – all from the anesthesiologist’s perspective. Discusses safe and effective perioperative anesthetic management of patients presenting with advanced levels of cardiac care such as drug-eluting stents, multiple antiplatelet drugs, ventricular assist devices, multiple drugs for end-stage heart failure, and implanted electrical devices that produce cardiac resynchronization therapy, as well as patients with complicated obstetric problems or other significant cardiovascular issues. Features a concise, easy-to-navigate format and Key Points boxes in each chapter that help you find answers quickly.

The Complete Recovery Room Book

The Complete Recovery Room Book
Author: Anne Craig,Anthea Hatfield
Publsiher: Oxford University Press, USA
Total Pages: 608
Release: 2021-01-10
ISBN 10: 0198846843
ISBN 13: 9780198846840
Language: EN, FR, DE, ES & NL

The Complete Recovery Room Book Book Review:

The Complete Recovery Room Book, Sixth edition is an essential resource for health care professionals involved in post-operative care.