100 Years of Human Chorionic Gonadotropin

100 Years of Human Chorionic Gonadotropin
Author: Laurence A. Cole,Stephen A. Butler
Publsiher: Unknown
Total Pages: 358
Release: 2020-02-17
ISBN 10: 0128200502
ISBN 13: 9780128200506
Language: EN, FR, DE, ES & NL

100 Years of Human Chorionic Gonadotropin Book Review:

100 years of Human Chorionic Gonadotropin: Reviews and New Perspectives is a collection of articles written by some of the world's leading experts on the pregnancy hormone and cancer marker hCG. In 2019 it is difficult to ignore the effect that our understanding of hCG has had on the lives of millions of people worldwide. The hCG immunoassay, in one form or another, is now one of the most common medical tests conducted and is often the first indication that a mother-to-be is pregnant. Not only a marker of pregnancy, hCG is utilized in the diagnosis and monitoring in oncology and presents a potential target for novel cancer therapeutics. 100 years ago, in 1919, Hirose was demonstrating gonadotropic functions which resulted from a chorionic factor. Over the last century this factor has become defined as hCG and more recently explored as not one molecule but a group of molecules with variable structure and variable functions in both pregnancy and cancer. hCG is a multi-faceted molecule that has clinical and therapeutic implications but can be a challenging topic for researchers and physicians alike. This text covers the different structures and functions of hCG exploring the genes and evolution of the molecule, the different protein and glycosylation structures which can exist and their effect on structure, detection and quantification. 100 Years of hCG is not an attempt to recount the history of every publication on hCG, but rather a collection of reviews and new perspectives by "hCG-ologists", the term used by Hussa to describe biochemists working on HCG in the first book written on the topic over 30 years ago. Some of the authors have been around a while, some not so long, but others are just beginning their journey with a most beguiling molecule. Provides updated information on a complex and changing subject in five sections Reviews historical perspectives and developments over the last 100 years Includes novel insights into the structure, function and detection of hCG in pregnancy and cancer Includes chapters on the use of mass spectrometry to detect and quantify hCG as well as traditional immunoassays and over the counter pregnancy tests Describes the role of hCG in pregnancy, endometrial receptivity and embryo implantation and the use in fertility treatment Addresses the specific hyperglycosylated hCG test that can distinguish a normal term from a failing pregnancy and also screen for preeclampsia and gestational hypertension in pregnancy as well as its use as a marker and treatment target in cancer. Includes chapters on the development and use of hCG vaccines Includes a section on hCG and in subunits in cancer

100 Years of Human Chorionic Gonadotropin

100 Years of Human Chorionic Gonadotropin
Author: Laurence A. Cole,Stephen A. Butler
Publsiher: Elsevier
Total Pages: 358
Release: 2020-02-07
ISBN 10: 0128216093
ISBN 13: 9780128216095
Language: EN, FR, DE, ES & NL

100 Years of Human Chorionic Gonadotropin Book Review:

100 years of Human Chorionic Gonadotropin: Reviews and New Perspectives is a collection of articles written by some of the world’s leading experts on the pregnancy hormone and cancer marker hCG. In 2019 it is difficult to ignore the effect that our understanding of hCG has had on the lives of millions of people worldwide. The hCG immunoassay, in one form or another, is now one of the most common medical tests conducted and is often the first indication that a mother-to-be is pregnant. Not only a marker of pregnancy, hCG is utilized in the diagnosis and monitoring in oncology and presents a potential target for novel cancer therapeutics. 100 years ago, in 1919, Hirose was demonstrating gonadotropic functions which resulted from a chorionic factor. Over the last century this factor has become defined as hCG and more recently explored as not one molecule but a group of molecules with variable structure and variable functions in both pregnancy and cancer. hCG is a multi-faceted molecule that has clinical and therapeutic implications but can be a challenging topic for researchers and physicians alike. This text covers the different structures and functions of hCG exploring the genes and evolution of the molecule, the different protein and glycosylation structures which can exist and their effect on structure, detection and quantification. 100 Years of hCG is not an attempt to recount the history of every publication on hCG, but rather a collection of reviews and new perspectives by "hCG-ologists", the term used by Hussa to describe biochemists working on HCG in the first book written on the topic over 30 years ago. Some of the authors have been around a while, some not so long, but others are just beginning their journey with a most beguiling molecule. Provides updated information on a complex and changing subject in five sections Reviews historical perspectives and developments over the last 100 years Includes novel insights into the structure, function and detection of hCG in pregnancy and cancer Includes chapters on the use of mass spectrometry to detect and quantify hCG as well as traditional immunoassays and over the counter pregnancy tests Describes the role of hCG in pregnancy, endometrial receptivity and embryo implantation and the use in fertility treatment Addresses the specific hyperglycosylated hCG test that can distinguish a normal term from a failing pregnancy and also screen for preeclampsia and gestational hypertension in pregnancy as well as its use as a marker and treatment target in cancer. Includes chapters on the development and use of hCG vaccines Includes a section on hCG and in subunits in cancer

Human Chorionic Gonadotropin hCG

Human Chorionic Gonadotropin  hCG
Author: Laurence A. Cole
Publsiher: Elsevier
Total Pages: 446
Release: 2014-12-11
ISBN 10: 0128008210
ISBN 13: 9780128008218
Language: EN, FR, DE, ES & NL

Human Chorionic Gonadotropin hCG Book Review:

Human chorionic gonadotropin (hCG) is produced during pregnancy by the embryo. It promotes progesterone production by corpus luteal cells. It also functions in pregnancy to promote angiogenesis in uterine vasculature, it immuno-blands the invading placental tissue so it is not rejected by the maternal uterine tissues, promotes the growth of the uterus in line with the growth of the fetus, promotes the differentiation of growing cytotrophoblast cells, promotes the quiescence of contractions in the uterine myometrium during the course of pregnancy, and also has function in growth and development of fetal organs. The first edition described the detailed biology, clinical chemistry, and clinical perspectives of hCG and associated molecules, and examines hCG, hyperglycosylated hCG and hCG free ß-subunit, 3 separate and independent molecules with totally sovereign physiological functions. The second edition will include coverage of the many new discoveries that have been made in the last five years: hCG analogues may be the actual driving signal of all human cancers. The editor estimates that 40% of the out of date material will be excluded and replaced with 40% of the exciting new findings. The book will also have a much clearer pregnancy and cancer focus. It provides comprehensive information on hCG from basic science to clinical medicine The second edition will include coverage of the many new discoveries that have been made in the last five years Updated material with new findings in the field

Chorionic Gonadotropin

Chorionic Gonadotropin
Author: Sheldon J. Segal
Publsiher: Springer Science & Business Media
Total Pages: 508
Release: 2012-12-06
ISBN 10: 1468410628
ISBN 13: 9781468410624
Language: EN, FR, DE, ES & NL

Chorionic Gonadotropin Book Review:

This volume is devoted to the chemistry, immunology, molecular biology, and physiology of the human chorionic gonadotropin, heG. For this glycoprotein molecule the course from discovery to chemical deciphering covered about fifty years. It was in 1928 that Ascheim and Zondek reported that urine from pregnant women contains something that stimulates the ovaries of mice or rats. This provided the basis for the famous A-Z test for pregnancy and for the "rabbit test" modification introduced by Friedman. As researchers sought to find more sensitive responses to heG, they used a wide variety of species including the South African aquatic toad, Xenopus Zaevis, the terrestrial toad of South America, Bufo arinarus, and the African weaver finch, EupZeetes afra. The weaver finch feather reaction was particularly noteworthy, for it disclosed a non-gonadal response to heG/LH. In retrospect, this may have been an important evolutionary clue to the realization that the designation of the hormone as a "gonadotropin" may have been only partially descriptive of the molecule's physiological function--a concept that is gaining attention, as the papers in this 1980 volume divulge.

Human Chorionic Gonadotropin hCG

Human Chorionic Gonadotropin  hCG
Author: Laurence A. Cole
Publsiher: Elsevier
Total Pages: 400
Release: 2010-09-21
ISBN 10: 012384908X
ISBN 13: 9780123849083
Language: EN, FR, DE, ES & NL

Human Chorionic Gonadotropin hCG Book Review:

Human chorionic gonadotropin (hCG) is produced during pregnancy by the embryo. It promotes progesterone production by corpus luteal cells. It also functions in pregnancy to promote angiogenesis in uterine vasculature, it immuno-blands the invading placental tissue so it is not rejected by the maternal uterine tissues, promotes the growth of the uterus in line with the growth of the fetus, promotes the differentiation of growing cytotrophoblast cells, promotes the quiescence of contractions in the uterine myometrium during the course of pregnancy, and also has function in growth and development of fetal organs. The book describes the detailed biology, clinical chemistry, and clinical perspectives of hCG and associated molecules, and examines hCG, hyperglycosylated hCG and hCG free ß-subunit, 3 separate and independent molecules with totally sovereign physiological functions. It provides comprehensive information on hCG from basic science to clinical medicine Written by specialists in the field

Human Chorionic Gonadotropin and Gonadotropin releasing Hormone Influence Pregnancy Survival and Resynchronized Ovulation Before Timed Artificial Insemination in Holstein Cattle

Human Chorionic Gonadotropin and Gonadotropin releasing Hormone Influence Pregnancy Survival and Resynchronized Ovulation Before Timed Artificial Insemination in Holstein Cattle
Author: Anonim
Publsiher: Unknown
Total Pages: 135
Release: 2008
ISBN 10: 1928374650XXX
ISBN 13: OCLC:191071113
Language: EN, FR, DE, ES & NL

Human Chorionic Gonadotropin and Gonadotropin releasing Hormone Influence Pregnancy Survival and Resynchronized Ovulation Before Timed Artificial Insemination in Holstein Cattle Book Review:

A study was performed to determine the minimum effective dose of human chorionic gonadotropin (hCG) needed to induce ovulation of follicles in cattle (Exp. 1). Another study determined the effects of replacing the first injection of GnRH (d -7) with hCG or saline in a Resynch-Ovsynch protocol [injection of GnRH 7 d before and 48 h after PGF[subscript2alpha] before a resynchronized fixed-timed AI (TAI)] on pregnancy rates in cows diagnosed not pregnant and pregnancy survival in cows diagnosed pregnant (d 0; Exp. 2). A final study determined the ovulation potential of hCG compared with GnRH and saline (Exp. 3). In Exp. 1, ovaries of Holstein cows were mapped by using transrectal ultrasonography 7 d before pregnancy diagnosis. Cows were assigned to treatments of saline, 100 [Mu]g of GnRH, or 500, 1,000, 2,000, or 3,000 IU of hCG. Ovarian structures were monitored 7 d later and proportion of cows and follicles that ovulated were recorded. In Exp. 2, cows in 4 herds were assigned to treatments of 1,000 IU of hCG, 100 [Mu]g of GnRH, or left as untreated controls 7 d before pregnancy diagnosis. Nonpregnant cows were given PGF[subscript2alpha] (d 0), then inseminated 72 h later, concurrent with a GnRH injection. Pregnancy rates tended (P = 0.08) to be increased by GnRH (17.9%; n = 703) compared with control (12.9%; n = 505), but not hCG (16.5%; n = 541). Incidences of ovulation in nonpregnant cows (Exp. 3) were: hCG (51.6%; n = 126), GnRH (46.1%; n = 102), and control (28.1%; n = 96), whereas those in pregnant cows were: hCG (59.3%; n = 59), GnRH (24.5%; n = 49), and control (6.9%; n = 58). We concluded that: 1) a minimum dose of 1,000 IU of hCG resulted in a greater ovulatory response than saline, GnRH, or 500 IU of hCG (Exp. 1); 2) initiating a Resynch-Ovsynch protocol 7 d before pregnancy diagnosis with saline reduced timed AI pregnancy rates (Exp. 2); and 3) incidence of new CL was greater after hCG than GnRH in pregnant cows, but not in nonpregnant cows (Exp. 3).

100 Years of Research

100 Years of Research
Author: Anonim
Publsiher: Unknown
Total Pages: 182
Release: 1983
ISBN 10: 1928374650XXX
ISBN 13: WISC:89037109469
Language: EN, FR, DE, ES & NL

100 Years of Research Book Review:

In Vitro Fertilization

In Vitro Fertilization
Author: Gabor Kovacs,Peter Brinsden,Alan DeCherney
Publsiher: Unknown
Total Pages: 256
Release: 2018-06-14
ISBN 10: 1108427855
ISBN 13: 9781108427852
Language: EN, FR, DE, ES & NL

In Vitro Fertilization Book Review:

A stimulating record chartering the history and pioneers of in-vitro fertilization, forty years after the birth of the first baby.

Animal Models in Eye Research

Animal Models in Eye Research
Author: Anonim
Publsiher: Academic Press
Total Pages: 232
Release: 2011-04-28
ISBN 10: 9780080921037
ISBN 13: 0080921035
Language: EN, FR, DE, ES & NL

Animal Models in Eye Research Book Review:

The eye is a complex sensory organ, which enables visual perception of the world. Thus the eye has several tissues that do different tasks. One of the most basic aspects of eye function is the sensitivity of cells to light and its transduction though the optic nerve to the brain. Different organisms use different ways to achieve these tasks. In this sense, eye function becomes a very important evolutionary aspect as well. This book presents the different animal models that are commonly used for eye research and their uniqueness in evaluating different aspects of eye development, evolution, physiology and disease. * Presents information on the major animal models used in eye research including invertebrates and vertebrates * Provides researchers with information needed to choose between model organisms * Includes an introductory chapter on the different types of eyes, stressing possible common molecular machinery

Weight Loss Advertising An Analysis of Current Trends A Federal Trade Commission staff report

Weight Loss Advertising  An Analysis of Current Trends A Federal Trade Commission staff report
Author: Anonim
Publsiher: DIANE Publishing
Total Pages: 135
Release: 2022
ISBN 10: 1428952810
ISBN 13: 9781428952812
Language: EN, FR, DE, ES & NL

Weight Loss Advertising An Analysis of Current Trends A Federal Trade Commission staff report Book Review:

Collected Reprints

Collected Reprints
Author: Anonim
Publsiher: Unknown
Total Pages: 135
Release: 1984
ISBN 10: 1928374650XXX
ISBN 13: STANFORD:36105210362344
Language: EN, FR, DE, ES & NL

Collected Reprints Book Review:

Veterinary Notes for Horse Owners

Veterinary Notes for Horse Owners
Author: Captain M. Horace Hayes,Roy Knightbridge
Publsiher: Simon and Schuster
Total Pages: 880
Release: 2002-06-18
ISBN 10: 0743234197
ISBN 13: 9780743234191
Language: EN, FR, DE, ES & NL

Veterinary Notes for Horse Owners Book Review:

A revised edition of the guide to equine health care provides comprehensive coverage of such topics as infectious diseases and health management, and provides new chapters on performance and artificial insemination. 15,000 first printing.

Immunological Methods in Microbiology

Immunological Methods in Microbiology
Author: Anonim
Publsiher: Academic Press
Total Pages: 410
Release: 2020-04-29
ISBN 10: 0128208120
ISBN 13: 9780128208120
Language: EN, FR, DE, ES & NL

Immunological Methods in Microbiology Book Review:

Immunological Methods in Microbiology, Volume 47 in the Methods in Microbiology series, highlights new advances in the field, with this new volume presenting interesting chapters on Immunological Techniques in the Clinical laboratory, Immunologic Diagnosis of HIV and Opportunistic Infections, Combining Antigen Detection and Serology for the Diagnosis of Selected Infectious Diseases, Immunologic Detection of Lyme Disease and Related Borrelioses, Immunodetection of Bacteria Causing Brucellosis, Immunological Diagnostic Techniques Used to Identify and Type Pasteurella, Immunological Tests for Diarrhea caused by Diarrheagenic Escherichia coli Targeting Their Main Virulence Factors, and much more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Methods in Microbiology series Includes the latest information on Immunological Methods in Microbiology

Human Gonadotropins

Human Gonadotropins
Author: Laurence A. Cole
Publsiher: Elsevier
Total Pages: 400
Release: 2020-07-01
ISBN 10: 0128226323
ISBN 13: 9780128226322
Language: EN, FR, DE, ES & NL

Human Gonadotropins Book Review:

Human Gonadotropins is a must-have reference for basic science researchers looking to maximize their knowledge in this specific field of study. Luteinizing hormone, follicle-stimulating hormone, and human chorionic gonadotropin are essential for reproduction and outlined in detail in this work, covering topics ranging from antibodies and immunoassays, to commercial products and standards, genetics, and receptors and intermediaries for gonadotropins. Dr. Laurence Cole has been recognized for his outstanding research throughout his illustrious career. He has received awards from the Institute for Anticancer Research, Biannual Prize for best research; American Association for Clinical Chemistry, Most Outstanding Research Contributor to Clinical Chemistry Prize; Gynecology Oncology, Outstanding Speaker Award; and International Society for Study of Trophoblastic Disease, Gold Medal for most outstanding research. This detailed resource compiles all the recent research together into one volume, with one consistent voice. Covers the evolution, structure, synthesis, and functions of gonadotropins in meticulous detail Includes sections on Degradation, Antibodies and Immunoassays, Commercial Products and Standards, and Receptors and Intermediaries Details a section on Reproduction and Cancer, covering gestational trophoblastic diseases, ovarian cystic disorders, and hCG and cancer

Target NTA NEET UG 2022 6 Solved Papers 2021 2017 10 Mock Papers 10th Edition

Target NTA NEET  UG  2022   6 Solved Papers  2021   2017    10 Mock Papers 10th Edition
Author: Disha Experts
Publsiher: Disha Publications
Total Pages: 460
Release: 2021-12-14
ISBN 10: 9355640412
ISBN 13: 9789355640413
Language: EN, FR, DE, ES & NL

Target NTA NEET UG 2022 6 Solved Papers 2021 2017 10 Mock Papers 10th Edition Book Review:

Target NEET 2022 - 6 Solved Papers (2021 - 2017) & 10 Mock Papers contains the detailed solutions of past 5 years of NEET exam solved question papers along with 10 Mock tests designed exactly as per the latest pattern. Each of the 10 Mock Tests provides 200 questions divided into 4 sections of 50 MCQs each - Physics, Chemistry, Zoology & Botany. Each section has 2 Parts - Part I of 35 compulsory MCQs; Part II of 15 MCQs where only 10 needs top be attempted. The book also contains the 2020 Retest paper held due to Covid. Thus in all, the book contains 6 Past Papers. The detailed solutions are self explanatory and provided for all the past papers & Mock Tests.

The Scandinavian Journal of Clinical Laboratory Investigation

The Scandinavian Journal of Clinical   Laboratory Investigation
Author: Anonim
Publsiher: Unknown
Total Pages: 135
Release: 1977
ISBN 10: 1928374650XXX
ISBN 13: UCLA:31158004951629
Language: EN, FR, DE, ES & NL

The Scandinavian Journal of Clinical Laboratory Investigation Book Review:

Marine Fish Culture

Marine Fish Culture
Author: John W. Tucker Jr.
Publsiher: Springer Science & Business Media
Total Pages: 750
Release: 1998-12-31
ISBN 10: 9780412071515
ISBN 13: 0412071517
Language: EN, FR, DE, ES & NL

Marine Fish Culture Book Review:

4 Water Sources ........................................ 149 Criteria ............................................. 149 Major types .. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 150 . . . . . . . . . . . . Summary ............................................ 152 5 Water Treatment ...................................... 155 Requirements . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 155 . . . . . . . . . . . . Materials ............................................ 155 Treatment options . . . . . . . . . . . . . . . . . . . . . . . . . . . 156 . . . . . . . . . . . System design ........................................ 169 System monitoring and control . . . . . . . . . . . . . . . . . . . . . 172 . . . . . . . . Environmental considerations .............................. 174 Summary ............................................ 174 6 Culture Units ......................................... 175 Considerations in choosing culture units ...................... 175 Characteristics of culture units . . . . . . . . . . . . . . . . . . . . . 175 . . . . . . . . Applications of culture units .............................. 191 Hatchery design " . . . . . . . . . . . . . . . . . . . . . . . . . . 208 . . . . . . . . . . . Summary ............................................ 210 7 Obtaining Fish for Stocking . ............................. 211 Stock from the wild .................................... 211 Stock from the hatchery ................................. 211 Spermatogenesis (sperm formation) ....................... 232 Oogenesis (egg formation) ............................. 232 Oocyte maturation ................................... 233 Endocrine control of oocyte maturation and ovulation .......... 237 fuduced ovulation . . . . . . . . . . . . . . . . . . . . . . . . . . 238 . . . . . . . . . . Timing and egg quality . . . . . . . . . . . . . . . . . . . . . . . 257 . . . . . . . . . Artificial fertilization ................................. 265 Care of eggs ....................................... 267 Storage of gametes ................. ' .................. 269 Natural ovulation . . . . . . . . . . . . . . . . . . . . . . . . . . 270 . . . . . . . . . . Care of broodfish . . . . . . . . . . . . . . . . . . . . . . . . . . 289 . . . . . . . . . . Egg collection .. . . . . . . . . . . . . . . . . . . . . . . . . . . 290 . . . . . . . . . . fuduced vs natural ovulation ............................ 290 Broodfish adaptability . . . . . . . . . . . . . . . . . . . . . . . . . 291 . . . . . . . . . . Examples ............................................ 291 Genetic considerations . . . . . . . . . . . . . . . . . . . . . . . . . 295 . . . . . . . . . . Hybridization . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 296 . . . . . . . . . . . . Sex control .......................................... 296 Summary . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 298 . . . . . . . . . . . . . vi 8 Nutrition of Larval Fish . . . . . . . . . . . . . . . . . . . . . . . 299 . . . . . . . . . . Feeding criteria ....................................... 299 Choice and culture of foods . . . . . . . . . . . . . . . . . . . . . . 307 . . . . . . . . . General feeding practices . . . . . . . . . . . . . . . . . . . . . . . 336 . . . . . . . . . . Specific feeding practices ................................ 352 General methods used in our hatchery . . . . . . . . . . . . . . . . . 372 . . . . . . . Industrial-scale larval food processing in Italian hatcheries ......... 373 Summary ............................................ 374 9 Nutrition of Juvenile and Adult Fish ...................... 375 ............................. 375 Requirements and components Broodstock nutrition .................................... 407 Nutritional disorders .................................... 408 Environmental considerations . . . . . . . . . . . . . . . . . . . . . 411 . . . . . . . . . Feed studies . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 411 . . . . . . . . . . . . Suggested feed formulas ................................. 460 Making and storing feeds ................................ 461 Feeding methods ...................................... 464 Summary ............................................ 467 10 Energetics ............................................ 469 Energy budget components and influencing factors . . . . . . . . . . . 469 . . . .

Immunology of Pregnancy 2013

Immunology of Pregnancy 2013
Author: Gérard Chaouat, Olivier Sandra and Nathalie Lédée
Publsiher: Bentham Science Publishers
Total Pages: 975
Release: 2013-11-08
ISBN 10: 160805733X
ISBN 13: 9781608057337
Language: EN, FR, DE, ES & NL

Immunology of Pregnancy 2013 Book Review:

Since a September, 1992, Nature article which read: “Can there be life without LIF?”, researchers now realize that the maternal immune system is both a foe (it can reject the conception) and a friend (immune cells and molecules are also necessary for successful pregnancy). Leukemia Inhibitory Factor (LIF) when absent, prevents embryo implantation in rodents. From fecundation to parturition, immunity acts as a Janus, required but potentially dangerous. However, the complexity and the diversity of immunity in pregnancy deters many from entering the field. This book will try to give a complete overview of immunity from gametes till parturition, in brief, but with complete chapters and subsections, each written by specialists in the field. The importance of the topic relies not only on “the riddle of the fetal allograft”, which is per se fascinating, but on its consequences, linked to the development of IVF and in general, Assisted Reproductive Technologies (ART) / Medicine. Since the discovery that there would not be (mammalian) life without LIF, it has become clear that Immune Molecules, and in general, transient post mating inflammatory reactions are required for successful implantation. Disruptions of this process can lead to implantation failure / sterility. In later stages of pregnancy immunological cells, mostly of the innate immune system, control formation of local spiral arteries. Finally, a state of tolerance establishes itself, whose “break’ leads to immune abortion and the vascular bed is further transformed and enlarged, till delivery, and here again “immunological cytokines” do play a major role and can eventually cause immune mediated abortion. Failure of, not just, the cytokine and cell recognition mediated dialogue, but also the pre and peri-implantation “preparation of the uterus”, as stated, leads to sterility, early pregnancy loss and recurrent abortions. There is also an increasingly stronger argument to implicate immunology in pre-eclampsia. Further still, immunology is also implicated in the control of local infection, mother to child transmission of pathogens (notably, but not limited to, HIV). Finally, pregnancy is the only known physiological phenomenon where the once named “suppressor T cells,” re-emerge as “regulatory T cells”, and play a cardinal role. This E-book provides a complete compendium of gynecological immunology, spanning from fecundation to delivery. Topics also include the role of various cell types (such as T regs ad NK cells) in implantation and uterine changes as well as the genetic regulation of immunological processes. As such it will be of interest not only to fundamental and reproductive immunologists, but more importantly, clinicians in obstetrics and gynecology.

Biology of Trophoblast

Biology of Trophoblast
Author: Y. W. Loke,A. Whyte
Publsiher: Elsevier Science Limited
Total Pages: 706
Release: 1983
ISBN 10: 1928374650XXX
ISBN 13: UOM:39015013589893
Language: EN, FR, DE, ES & NL

Biology of Trophoblast Book Review:

Advances in Cancer Biomarkers

Advances in Cancer Biomarkers
Author: Roberto Scatena
Publsiher: Springer
Total Pages: 372
Release: 2015-11-03
ISBN 10: 9401772150
ISBN 13: 9789401772150
Language: EN, FR, DE, ES & NL

Advances in Cancer Biomarkers Book Review:

At present there are a growing number of biomolecules under investigation to understand their potential role as cancer biomarker for diagnostic, prognostic and therapeutic purposes. Intriguingly, the state of art on cancer biomarkers research shows interesting and promising results together to clamorous failures. Also from a clinical point of view, there are contradictory results on routine clinical use of the present cancer biomarkers. Some patients may be simply monitored in their course by a periodic blood sample, but sometimes this monitoring shows dramatic limits. A lot of patients show serious and extensive relapses without significant change in serum concentrations of biomarkers tested. Often the physician who should utilize these biomarker does not entirely know their limits and the total potential applications as well and sometimes this knowledge is influenced by economical and marketing strategies. This limited and “polluted” knowledge may have dramatic consequences for patient. The aim of this book is to diffuse all aspects of cancer biomarkers, from their biochemical peculiarities to all clinical implications by passing through their physiology and pathophysiology. This critical approach towards old and new cancer biomarkers should foster a deepened and useful understanding of the diagnostic and prognostic index of these fundamental parameters of laboratory medicine and in the same time facilitating the research of new and more sensitive-specific signals of the cancer cell proliferation.